TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T26617	Lactase-phlorizin hydrolase	D0D0ZD	Miglitol	Approved	441314	C8H17NO5	207.22	C1[C@@H]([C@H]([C@@H]([C@H](N1CCO)CO)O)O)O	IC50 = 50000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	D0HR8Z	Miglustat	Approved	51634	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	D0MU9L	Migalastat	Approved	176077	C6H13NO4	163.17	C1[C@@H]([C@H]([C@H]([C@H](N1)CO)O)O)O	IC50 = 50000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	D0S5LT	Deoxynojirimycin	Phase 3	29435	C6H13NO4	163.17	C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O	IC50 = 62000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B2HKB1	(2R,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118411077	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@H](N1CC(CCCOCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B2O6HK	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411070	C24H33NO5	415.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC=C(C=C2)C3=CC=CC=C3)CO)O)O)O	IC50 = 80000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B4NZ6J	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720306	C24H33NO5	415.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=CC=C2)C3=CC=CC=C3)CO)O)O)O	IC50 = 60000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B54YTP	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720304	C25H35NO5	429.5	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2)OCCCCCN3C[C@@H]([C@H]([C@@H]([C@@H]3CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B58IZE	N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deoxynojirimycin	Investigative	11258014	C22H39NO5	397.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC23CC4CC(C2)CC(C4)C3)CO)O)O)O	IC50 = 200000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	B7N5OH	(2S,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118411069	C24H32FNO5	433.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=C(C=C(C=C2)C3=CC=CC=C3)F)CO)O)O)O	IC50 = 60000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BDZ60T	(2S,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118720307	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CC(CCCOCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BM60EO	(2S)-1-[5-(2-Fluoro-1,1'-biphenyl-4-ylmethoxy)pentyl]-2beta-(hydroxymethyl)piperidine-3beta,4alpha,5beta-triol	Investigative	101882900	C24H32FNO5	433.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=C(C=C2)C3=CC=CC=C3)F)CO)O)O)O	IC50 = 50000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BNFR84	(2S,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118720308	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCC(COCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 = 80000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BU4R8D	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411149	C25H32F3NO5	483.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CO)O)O)O	IC50 = 100000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BXU1E0	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411108	C25H32F3NO5	483.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=C(C=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CO)O)O)O	IC50 = 125000 nM	Poor binder
T26617	Lactase-phlorizin hydrolase	BY13BK	(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411071	C25H32F3NO5	483.5	C1[C@@H]([C@H]([C@@H]([C@H](N1CCCCCOCC2=C(C=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CO)O)O)O	IC50 = 50000 nM	Poor binder