TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T28052	Lysine-specific demethylase 5A	D0L5WM	Amiodarone	Approved	2157	C25H29I2NO3	645.3	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I	IC50 = 99000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B1L5ZS	Chembl4299285	Investigative	145949030	C101H171N37O29	2367.7	CC(C)C[C@H](C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CO)C(=O)N[C@H](CC(=O)O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](CC(=O)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N3CCC[C@@H]3C(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](CC4=CC=C(C=C4)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(=O)N)C(=O)N)NC(=O)[C@@H](CCCNN)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5	IC50 ~ 50000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B1X3WP	2-(Methylamino)-7-[3-(3-phenoxyphenyl)acryloyl]-2,4,6-cycloheptatrien-1-one	Investigative	5852401	C23H19NO3	357.4	CNC1=CC=CC=C(C1=O)C(=O)/C=C/C2=CC(=CC=C2)OC3=CC=CC=C3	IC50 = 64000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B5B8UQ	3-[3-[Butyl(methyl)amino]propanoyl-hydroxyamino]propanoic acid	Investigative	122181578	C11H22N2O4	246.3	CCCCN(C)CCC(=O)N(CCC(=O)O)O	IC50 = 53000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B6FJO5	Chembl4129830	Investigative	145960532	C25H30F2INO3	557.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)F)OCCC[N+](C)(C)C)F.[I-]	IC50 = 198000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B6UZ0B	3-(9-Cycloheptylnonanoylhydroxyamino)propionic acid	Investigative	71735842	C19H35NO4	341.5	C1CCCC(CC1)CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 55000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	B9ES5B	3-(10-Methylundecanoylhydroxyamino)propionic acid	Investigative	73352277	C15H29NO4	287.39	CC(C)CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 110000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BA28NV	Chembl4130224	Investigative	145962269	C25H32INO3	521.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCC[N+](C)(C)C.[I-]	Ki = 74000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BB4I2V	3-(9-Phenylnonanoylhydroxyamino)propionic acid	Investigative	71735840	C18H27NO4	321.4	C1=CC=C(C=C1)CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 93000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BBZ6H0	Chembl4126135	Investigative	145963156	C22H25NO3	351.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCCN	IC50 = 198000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BCG7Z1	3-(9-Cyclohexylnonanoylhydroxyamino)propionic acid	Investigative	71735687	C18H33NO4	327.5	C1CCC(CC1)CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 100000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BCYX23	Chembl4126951	Investigative	145962553	C24H29NO3	379.5	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCCN(C)C	IC50 = 166000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BDB1F6	Chembl4299338	Investigative	145948690	C102H173N37O29	2381.7	CC(C)C[C@H](C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CO)C(=O)N[C@H](CC(=O)O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](CC(=O)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N3CCC[C@@H]3C(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](CC4=CC=C(C=C4)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(=O)N)C(=O)N)NC(=O)[C@@H](CCCNNC)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5	IC50 ~ 50000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BGB3C6	N-{(3S)-1-[5-(Propan-2-yl)-1H-pyrazole-3-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide	Investigative	129606887	C15H22N4O2	290.36	CC(C)C1=CC(=NN1)C(=O)N2CC[C@@H](C2)NC(=O)C3CC3	IC50 = 140000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BKUM37	2-[5-[2-(3-Methoxyphenyl)ethanoylamino]-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	Investigative	135567042	C21H18N2O5	378.4	COC1=CC=CC(=C1)CC(=O)NC2=CC(=C(C=C2)O)C3=NC=CC(=C3)C(=O)O	IC50 = 52000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BL60AE	Chembl4129540	Investigative	70702121	C25H30I3NO3	773.2	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCC[N+](C)(C)C)I.[I-]	IC50 = 82000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BO0H6J	3-(Decanoylhydroxyamino)propionic acid	Investigative	71735839	C13H25NO4	259.339	CCCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 64000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BOEX72	Chembl4276959	Investigative	145985174	C22H25N3O3S	411.5	C1CCN(CC1)CCOC(C2=CC(=CC=C2)N)C3=CC4=NC=CC(=C4S3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BQ6MP1	Chembl4294426	Investigative	137349487	C19H24N6O4S	432.5	C=CS(=O)(=O)N1CCCN(CC1)C2=NC(=NC(=C2)NCCC(=O)O)C3=CC=CC=N3	IC50 = 83000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BSY1E4	N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-beta-alanine	Investigative	71735843	C15H27NO4	285.38	C1CC1CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 = 55000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BY36HT	2-[5-(2-Methoxyethanoylamino)-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	Investigative	135567037	C15H14N2O5	302.28	COCC(=O)NC1=CC(=C(C=C1)O)C2=NC=CC(=C2)C(=O)O	IC50 = 180000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BY4L8W	3-Chloro-1-(2,3-dimethylphenyl)-4-(ethylanilino)-1H-pyrrole-2,5-dione	Investigative	992337	C20H19ClN2O2	354.8	CCN(C1=CC=CC=C1)C2=C(C(=O)N(C2=O)C3=CC=CC(=C3C)C)Cl	IC50 = 83000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BZ3M9W	Methyl 3-[hydroxy-[5-[methyl(pentyl)amino]pentanoyl]amino]propanoate	Investigative	122181589	C15H30N2O4	302.41	CCCCCN(C)CCCCC(=O)N(CCC(=O)OC)O	IC50 = 63000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	BZL36S	Chembl4283844	Investigative	133053816	C20H24N6O3	396.4	C=CC(=O)N1CCCN(CC1)C2=NC(=NC(=C2)NCCC(=O)O)C3=CC=CC=N3	IC50 = 71000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	D07IOY	Pyridine-2,4-dicarboxylic acid	Investigative	10365	C7H5NO4	167.12	C1=CN=C(C=C1C(=O)O)C(=O)O	IC50 = 100000 nM	Poor binder
T28052	Lysine-specific demethylase 5A	D0S3DD	GSK-J1	Investigative	56963315	C22H23N5O2	389.4	C1CN(CCC2=CC=CC=C21)C3=NC(=NC(=C3)NCCC(=O)O)C4=CC=CC=N4	IC50 = 110000 nM	Poor binder