TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T28484	Kinesin-like protein KIF11	D0X5SI	Carbocisteine	Approved	193653	C5H9NO4S	179.2	C([C@@H](C(=O)O)N)SCC(=O)O	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	D0L4VI	L-cysteine	Clinical trial	5862	C3H7NO2S	121.16	C([C@@H](C(=O)O)N)S	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B01VTU	3-N,3-N,6-Triethyl-2-N-(thiophene-2-)-4,5,6,7-tetrahydro-1-benzothiophene-2,3-diamido	Investigative	24901575	C20H26N2O2S2	390.6	CCC1CCC2=C(C1)SC(=C2C(=O)N(CC)CC)NC(=O)C3=CC=CS3	IC50 = 69000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B0E1DO	3-[5-(2-Chloro-phenyl)-2-methyl-3,4-dihydro-2H-pyrazol-3-yl]-phenol	Investigative	44401864	C16H15ClN2O	286.75	CN1C(CC(=N1)C2=CC=CC=C2Cl)C3=CC(=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B0LQF4	Chembl4244405	Investigative	145985512	C25H25N5O2S2	491.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C=C/C3=CC=C(C=C3)N(C)C)/S2)(C)C4=CC=CC=C4	IC50 = 128700 nM	Poor binder
T28484	Kinesin-like protein KIF11	B0Y3KQ	1-Acetyl-3-(2-methoxyphenyl)-5-phenyl-2-pyrazoline	Investigative	44401990	C18H18N2O2	294.3	CC(=O)N1C(CC(=N1)C2=CC=CC=C2OC)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B13FQV	Fmoc-Cys(Trt)-OH	Investigative	128239	C37H31NO4S	585.7	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)SC[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46	IC50 = 55000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B1QK6V	2-(2-Morpholinoethylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45271267	C22H23F3N4O3	448.4	C1COCCN1CCNC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B2FQ5H	(R)-2-(Tritylamino)-3-(tritylthio)propanoic acid	Investigative	14081820	C41H35NO2S	605.8	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N[C@@H](CSC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C(=O)O	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B2U8ML	Chembl4242214	Investigative	145982560	C23H22N4O4S2	482.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC(=C(C=C3)OC)OC)/S2)(C)C4=CC=CC=C4	IC50 = 60000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B2YN0U	(R)-2-Amino-3-(tert-butylthio)propanoic acid	Investigative	6951058	C7H15NO2S	177.27	CC(C)(C)SC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B3K6IN	S-Diphenylmethyl-L-cysteine	Investigative	21261	C16H17NO2S	287.4	C1=CC=C(C=C1)C(C2=CC=CC=C2)SC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B3ZS4Q	Chembl4249742	Investigative	145983379	C23H22N4O4S2	482.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=C(C(=CC=C3)OC)OC)/S2)(C)C4=CC=CC=C4	IC50 = 71900 nM	Poor binder
T28484	Kinesin-like protein KIF11	B4D7VH	3-N,3-N-Diethyl-2-N-(thiophene-2-)thiophene-2,3-diamido	Investigative	24901561	C14H16N2O2S2	308.4	CCN(CC)C(=O)C1=C(SC=C1)NC(=O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B53FPG	Chembl4246927	Investigative	145983831	C19H16N4O2S3	428.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=CS3)/S2)(C)C4=CC=CC=C4	IC50 = 133500 nM	Poor binder
T28484	Kinesin-like protein KIF11	B5SZ1H	Chembl4246993	Investigative	145984551	C23H23N5O2S2	465.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=C(C=C3)N(C)C)/S2)(C)C4=CC=CC=C4	IC50 = 90000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B6A4PQ	S-(2-Aminoethyl)-L-cysteine	Investigative	99558	C5H12N2O2S	164.23	C(CSC[C@@H](C(=O)O)N)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B6V8RW	Chembl4239372	Investigative	145985905	C24H22N4O3S2	478.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C=C/C3=CC=C(C=C3)OC)/S2)(C)C4=CC=CC=C4	IC50 = 90000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B81AOR	3-N,3-N-Diethyl-2-N-(thiophene-2-)-1-benzothiophene-2,3-diamido	Investigative	24901579	C18H18N2O2S2	358.5	CCN(CC)C(=O)C1=C(SC2=CC=CC=C21)NC(=O)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B8E1PY	2-(Thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid	Investigative	703864	C14H13NO3S2	307.4	C1CCC2=C(C1)C(=C(S2)NC(=O)C3=CC=CS3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B9B2UA	4-({[3-(Methoxycarbonyl)-2-methylnaphtho[1,2-b]furan-5-yl]amino}sulfonyl)benzoic acid	Investigative	9541651	C22H17NO7S	439.4	CC1=C(C2=C(O1)C3=CC=CC=C3C(=C2)NS(=O)(=O)C4=CC=C(C=C4)C(=O)O)C(=O)OC	IC50 = 79100 nM	Poor binder
T28484	Kinesin-like protein KIF11	B9HV4Z	Chembl4239414	Investigative	145982524	C19H16N4O3S2	412.5	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=CO3)/S2)(C)C4=CC=CC=C4	IC50 = 120000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B9OSM1	3-N,3-N-Diethyl-2-N-(thiophene-2-)-4H,5H,6H,7H-thieno[2,3-c]pyridine-2,3-diamido	Investigative	24901578	C17H21N3O2S2	363.5	CCN(CC)C(=O)C1=C(SC2=C1CCNC2)NC(=O)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	B9XLH6	(R)-Methyl 2-acetamido-3-((4-methoxyphenyl)diphenylmethylthio)propanoate	Investigative	25014751	C26H27NO4S	449.6	CC(=O)N[C@@H](CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC)C(=O)OC	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BAH96I	Ethyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate	Investigative	391237	C16H17NO3S2	335.4	CCOC(=O)C1=C(SC2=C1CCCC2)NC(=O)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BCRQ94	H-Cys(pMeOBzl)-OH	Investigative	7009563	C11H15NO3S	241.31	COC1=CC=C(C=C1)CSC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BEL05R	Boc-Cys(Trt)-OH	Investigative	11167161	C27H29NO4S	463.6	CC(C)(C)OC(=O)N[C@@H](CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BEW0Y6	Chembl4246224	Investigative	145985999	C22H20N4O2S2	436.6	CC1=CC=C(C=C1)/C=C\\2/C(=O)N/C(=N\\C3=NN(C(S3)(C)C4=CC=CC=C4)C(=O)C)/S2	IC50 = 63300 nM	Poor binder
T28484	Kinesin-like protein KIF11	BF1B9S	2-(2-Aminoethylsulfanyl)-1,2,2-triphenylethanone	Investigative	66572226	C22H21NOS	347.5	C1=CC=C(C=C1)C(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)SCCN	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BF3XA7	N-[3-(Diethylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,3-thiazole-5-carboxamide	Investigative	24901564	C17H21N3O2S2	363.5	CCN(CC)C(=O)C1=C(SC2=C1CCCC2)NC(=O)C3=CN=CS3	IC50 = 76000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BF7NS9	Chembl4241249	Investigative	145984469	C21H17ClN4O2S2	457	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=C(C=C3)Cl)/S2)(C)C4=CC=CC=C4	IC50 = 106200 nM	Poor binder
T28484	Kinesin-like protein KIF11	BFS36Z	1-[5-Phenyl-3-(2-trifluoromethyl-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	44401991	C18H15F3N2O	332.3	CC(=O)N1C(CC(=N1)C2=CC=CC=C2C(F)(F)F)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BG87RK	Chembl4288725	Investigative	145991640	C16H15N3O2S	313.4	CC(=O)NC1=NN(C(S1)C2=CC=CC3=CC=CC=C32)C(=O)C	IC50 = 53900 nM	Poor binder
T28484	Kinesin-like protein KIF11	BI16BF	Chembl4243138	Investigative	145983532	C22H20N4O3S2	452.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC(=CC=C3)OC)/S2)(C)C4=CC=CC=C4	IC50 = 51000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BIOS75	Chembl4293322	Investigative	145987224	C12H14N4O2S	278.33	CC(=O)NC1=NN(C(S1)(C)C2=CC=NC=C2)C(=O)C	IC50 = 59900 nM	Poor binder
T28484	Kinesin-like protein KIF11	BJC6R7	Chembl4251217	Investigative	145983171	C20H17N5O2S2	423.5	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=CC=N3)/S2)(C)C4=CC=CC=C4	IC50 = 120000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BKV12T	2-(Thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide	Investigative	675901	C14H14N2O2S2	306.4	C1CCC2=C(C1)C(=C(S2)NC(=O)C3=CC=CS3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BL81BS	Chembl4247167	Investigative	145983110	C21H17FN4O2S2	440.5	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=CC=C3F)/S2)(C)C4=CC=CC=C4	IC50 = 70000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BL9UE8	S-Methyl-L-cysteine	Investigative	24417	C4H9NO2S	135.19	CSC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BN1PK4	Chembl4243604	Investigative	145985964	C23H20N4O2S2	448.6	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C=C/C3=CC=CC=C3)/S2)(C)C4=CC=CC=C4	IC50 = 75000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BNE6Z1	1H-Pyrazole, 1-acetyl-3-(4-chlorophenyl)-4,5-dihydro-5-phenyl-	Investigative	14741508	C17H15ClN2O	298.8	CC(=O)N1C(CC(=N1)C2=CC=C(C=C2)Cl)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BO92BI	(R)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid	Investigative	7019695	C17H17NO2S	299.4	C1=CC=C2C(=C1)C(C3=CC=CC=C32)CSC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BQ1N8U	Ac-Cys(Trt)-OH	Investigative	7408363	C24H23NO3S	405.5	CC(=O)N[C@@H](CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BR3H1Y	Chembl4247682	Investigative	145985314	C21H18N4O2S2	422.5	CC(=O)N1C(SC(=N1)/N=C/2\\NC(=O)/C(=C/C3=CC=CC=C3)/S2)(C)C4=CC=CC=C4	IC50 = 62100 nM	Poor binder
T28484	Kinesin-like protein KIF11	BRN3I4	(R)-2-Amino-3-(diphenyl(thiophen-2-yl)methylthio)propanoic acid	Investigative	53326599	C20H19NO2S2	369.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CS3)SC[C@@H](C(=O)O)N	Ki = 58333 nM	Poor binder
T28484	Kinesin-like protein KIF11	BSG2Z9	1-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone	Investigative	207753	C17H16N2O	264.32	CC(=O)N1C(CC(=N1)C2=CC=CC=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BSU56E	(2R)-4-(2,5-Difluorophenyl)-N,N-dimethyl-2-phenyl-2,5-dihydropyrrole-1-carboxamide	Investigative	44409515	C19H18F2N2O	328.4	CN(C)C(=O)N1CC(=C[C@@H]1C2=CC=CC=C2)C3=C(C=CC(=C3)F)F	IC50 = 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BX3UI9	3-(2-Chloro-phenyl)-5-(3-hydroxy-phenyl)-4,5-dihydro-pyrazole-1-carboxylic acid methyl ester	Investigative	44401865	C17H15ClN2O3	330.8	COC(=O)N1C(CC(=N1)C2=CC=CC=C2Cl)C3=CC(=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T28484	Kinesin-like protein KIF11	BXF8E1	(2R)-2-Amino-3-(2-oxo-1,1,2-triphenylethyl)sulfanylpropanoic acid	Investigative	66572224	C23H21NO3S	391.5	C1=CC=C(C=C1)C(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)SC[C@@H](C(=O)O)N	IC50 ~ 150000 nM	Poor binder
T28484	Kinesin-like protein KIF11	D0S0JL	Benzylcysteine	Investigative	193613	C10H13NO2S	211.28	C1=CC=C(C=C1)CSC[C@@H](C(=O)O)N	IC50 ~ 63000 nM	Poor binder
T28484	Kinesin-like protein KIF11	D0S7AY	NSC-125034	Investigative	276707	C18H12N2O2S2	352.4	C1=CC2=C(C(=C1)O)N=C(C=C2)SSC3=NC4=C(C=CC=C4O)C=C3	IC50 = 145000 nM	Poor binder