TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T28893	Muscarinic acetylcholine receptor M1	D0Q9HF	Acetylcholine	Approved	187	C7H16NO2+	146.21	CC(=O)OCC[N+](C)(C)C	EC50 = 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	D0U7BW	Carbachol	Approved	2551	C6H15N2O2+	147.2	C[N+](C)(C)CCOC(=O)N	Ki = 63000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B01URL	N-Cyclohexyl-2-(4-propanoylpiperazin-1-yl)acetamide	Investigative	49853778	C15H27N3O2	281.39	CCC(=O)N1CCN(CC1)CC(=O)NC2CCCCC2	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B1ELB7	Pyrrolidine, 2-(2-furanyl)-1-methyl-, (2R)-	Investigative	24894515	C9H13NO	151.21	CN1CCC[C@@H]1C2=CC=CO2	Ki = 77624.71 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B1Z0TB	N,N,N-Trimethyl-alpha-(2-oxooxazolidine-5beta-yl)methaneaminium	Investigative	73349591	C7H15N2O2+	159.21	C[N+](C)(C)C[C@@H]1CNC(=O)O1	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B2DOR6	6,7,8,9-Tetrahydro-[1,2,5]thiadiazolo[3,4-h]isoquinoline	Investigative	14660293	C9H9N3S	191.26	C1CNCC2=C1C=CC3=NSN=C23	IC50 = 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B2NL1J	5-(4-Butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydropyridine	Investigative	15033741	C12H19N3OS	253.37	CCCCOC1=NSN=C1C2=CCCN(C2)C	IC50 = 77624.71 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B32CXR	(2R,3R,5R)-5-[(2S)-1,1-Dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide	Investigative	11523050	C10H20INO2S	345.24	C[C@@H]1O[C@@H](C[S@]1=O)[C@@H]2CCC[N+]2(C)C.[I-]	Ki = 93325.43 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B3OJ9Q	Ethyl 1-[2-(4-methoxyphenyl)ethyl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574179	C23H27NO3	365.5	CCOC(=O)C1=C(CCN(C1)CCC2=CC=C(C=C2)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B40KXW	Trimethyl-[[(2R,3R)-3-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	118706052	C9H20INO2	301.17	C[C@@H]1[C@H](OCCO1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B40WHA	(4R)-4-[(2S)-1-Methylpyrrolidin-2-yl]-1,3-oxazolidin-2-one	Investigative	72545091	C8H14N2O2	170.21	CN1CCC[C@H]1[C@@H]2COC(=O)N2	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B4BM5X	N-Pentan-3-yl-2-(4-propanoylpiperazin-1-yl)acetamide	Investigative	49853777	C14H27N3O2	269.38	CCC(CC)NC(=O)CN1CCN(CC1)C(=O)CC	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B4L6GV	(2R)-1,1-Dimethyl-2-[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]pyrrolidin-1-ium	Investigative	11819782	C10H20NO2+	186.27	C[C@H]1OC[C@H](O1)[C@H]2CCC[N+]2(C)C	Ki = 52480.75 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B4QAO5	3-(4-Imidazol-1-ylbutoxy)-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole	Investigative	44456863	C15H21N5OS	319.4	CN1CCC=C(C1)C2=NSN=C2OCCCCN3C=CN=C3	IC50 = 52480.75 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B4YCF2	[(2S)-1-(4-Methoxyphenyl)propan-2-yl] 1-ethyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575028	C24H29NO3	379.5	CCN1CCC(=C(C1)C(=O)O[C@@H](C)CC2=CC=C(C=C2)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5BZO0	2-(4-Methoxyphenyl)ethyl 1-[(4-methoxyphenyl)methyl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575336	C29H31NO4	457.6	COC1=CC=C(C=C1)CCOC(=O)C2=C(CCN(C2)CC3=CC=C(C=C3)OC)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5ER0C	(5S)-5-[(Dimethylamino)methyl]-3-methyl-1,3-oxazolidin-2-one	Investigative	58653718	C7H14N2O2	158.2	CN1C[C@@H](OC1=O)CN(C)C	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5EZF0	(2S)-2-(Furan-2-yl)pyrrolidine	Investigative	7022778	C8H11NO	137.18	C1C[C@H](NC1)C2=CC=CO2	Ki = 63095.73 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5J4WP	N,N,N-Trimethyl-alpha-(2-oxooxazolidine-5alpha-yl)methaneaminium	Investigative	73349592	C7H15N2O2+	159.21	C[N+](C)(C)C[C@H]1CNC(=O)O1	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5ONL2	Trimethyl-[[(5S)-3-methyl-2-oxo-1,3-oxazolidin-5-yl]methyl]azanium	Investigative	72545329	C8H17N2O2+	173.23	CN1C[C@H](OC1=O)C[N+](C)(C)C	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5V6JQ	2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl 1-butyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575449	C26H31NO3	405.5	CCCCN1CCC(=C(C1)C(=O)OCCC2=CC3=C(C=C2)OCC3)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B5XTH8	5-[[(E)-1-Azabicyclo[2.2.2]octan-3-ylmethylideneamino]oxymethyl]-1,2-oxazole-3-carbonitrile;hydrochloride	Investigative	49796412	C13H17ClN4O2	296.75	C1CN2CCC1C(C2)/C=N/OCC3=CC(=NO3)C#N.Cl	IC50 = 132700 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B67YHI	6-Chloro-3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline	Investigative	24894134	C22H17Cl2FN4O	443.3	C1CN(CCC1C2=NC(=NO2)C3=C(C=C(C=C3)F)Cl)C4=CN=C5C=CC(=CC5=C4)Cl	IC50 ~ 50000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B75HGX	1-[3-[4-[9-[[4-(1-Methyl-1,2,5,6-tetrahydropyridine-3-yl)-1,2,5-thiadiazole-3-yl]oxy]nonyl]piperidino]propyl]-3,4-dihydro-2(1H)-quinolinone	Investigative	101882890	C34H51N5O2S	593.9	CN1CCC=C(C1)C2=NSN=C2OCCCCCCCCCC3CCN(CC3)CCCN4C(=O)CCC5=CC=CC=C54	EC50 = 61659.5 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B7GRA8	2-(3,4,5-Trimethoxyphenyl)ethyl 1-ethyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575221	C25H31NO5	425.5	CCN1CCC(=C(C1)C(=O)OCCC2=CC(=C(C(=C2)OC)OC)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B7H4JI	4-[[4-(1-Methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]butan-1-amine	Investigative	44456577	C12H20N4OS	268.38	CN1CCC=C(C1)C2=NSN=C2OCCCCN	IC50 = 77624.71 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B8ACZ5	(5R)-5-[(Dimethylamino)methyl]-3-methyl-1,3-oxazolidin-2-one	Investigative	72545094	C7H14N2O2	158.2	CN1C[C@H](OC1=O)CN(C)C	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B8CRU7	(5S,2''S)-5-(1-Methyl-2-pyrrolidinyl)oxazolidinone	Investigative	44571572	C8H14N2O2	170.21	CN1CCC[C@H]1[C@@H]2CNC(=O)O2	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B8F7GE	5-[[(E)-1-Azabicyclo[2.2.1]heptan-3-ylmethylideneamino]oxymethyl]-1,2-oxazole-3-carbonitrile;hydrochloride	Investigative	49796407	C12H15ClN4O2	282.72	C1CN2CC1C(C2)/C=N/OCC3=CC(=NO3)C#N.Cl	IC50 = 189500 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B8FM1A	Trimethyl-[[(2R)-2-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	118706050	C9H20INO2	301.17	C[C@]1(COCCO1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B8GY1Q	[(2R,5S,6R)-5,6-Dimethyl-1,4-dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	46227416	C10H22INO2	315.19	C[C@H]1[C@H](O[C@@H](CO1)C[N+](C)(C)C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B91SJZ	2-[[4-(1-Methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]ethanamine	Investigative	44456598	C10H16N4OS	240.33	CN1CCC=C(C1)C2=NSN=C2OCCN	IC50 = 109647.82 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B95YCK	2-(3,4-Dimethoxyphenyl)ethyl 4-(3-methoxyphenyl)-1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574176	C24H29NO5	411.5	CN1CCC(=C(C1)C(=O)OCCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OC	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	B9LTS0	Pyrrolidine, 2-(5-methyl-2-furanyl)-, (2S)-	Investigative	7141654	C9H13NO	151.21	CC1=CC=C(O1)[C@@H]2CCCN2	Ki = 154881.66 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BAF32L	2-(3-Methoxyphenyl)ethyl-trimethylazanium;formate	Investigative	137655796	C13H21NO3	239.31	C[N+](C)(C)CCC1=CC(=CC=C1)OC.C(=O)[O-]	Ki = 52000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BAP06W	Flaxedil	Investigative	3450	C30H60N3O3+3	510.8	CC[N+](CC)(CC)CCOC1=C(C(=CC=C1)OCC[N+](CC)(CC)CC)OCC[N+](CC)(CC)CC	EC50 = 170000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BB30RM	Esaprazole	Investigative	68835	C12H23N3O	225.33	C1CCC(CC1)NC(=O)CN2CCNCC2	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BB9YX3	N-Isopropyl-1-piperazineacetamide	Investigative	100826	C9H19N3O	185.27	CC(C)NC(=O)CN1CCNCC1	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BC5Y0W	(S)-5beta-[(Dimethylamino)methyl]oxazolidine-2-one	Investigative	73351145	C6H12N2O2	144.17	CN(C)C[C@@H]1CNC(=O)O1	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BCJ98E	Trimethyl-[[(2R,5R)-5-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	46227554	C9H20INO2	301.17	C[C@@H]1CO[C@@H](CO1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BD7H1A	1-Aza-bicyclo[2.2.1]heptan-3-one O-methyl-oxime	Investigative	10240891	C7H12N2O	140.18	CO/N=C/1\\CN2CCC1C2	IC50 = 85050 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BDA42Y	2,3-Dihydro-1-benzofuran-5-ylmethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575451	C22H23NO3	349.4	CN1CCC(=C(C1)C(=O)OCC2=CC3=C(C=C2)OCC3)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BDPT63	[(2S)-1-Methylpyrrolidin-2-yl]methyl carbamate	Investigative	72545089	C7H14N2O2	158.2	CN1CCC[C@H]1COC(=O)N	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BEKD26	Trimethyl-[[(2S,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	44422696	C9H20INO2	301.17	C[C@H]1COC[C@@H](O1)C[N+](C)(C)C.[I-]	Ki = 74131.02 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BG5E7Y	1,4-Dimethyl-3-(4-methylthio-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydropyridine	Investigative	10354348	C10H15N3S2	241.4	CC1=C(CN(CC1)C)C2=NSN=C2SC	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BGAU76	2-(3,4-Dimethoxyphenyl)ethyl 4-(2-fluorophenyl)-1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574175	C23H26FNO4	399.5	CN1CCC(=C(C1)C(=O)OCCC2=CC(=C(C=C2)OC)OC)C3=CC=CC=C3F	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BGH14T	Ethyl 1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574180	C24H27NO3	377.5	CCOC(=O)C1=C(CCN(C1)CCC2=CC3=C(C=C2)OCC3)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BGM1F0	2-[(8Ar)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-cyclohexylacetamide	Investigative	49853883	C15H27N3O	265.39	C1CCC(CC1)NC(=O)CN2CCN3CCC[C@@H]3C2	IC50 = 56000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BH7I2B	N-[2-(Dimethylamino)ethyl]-3-(pyridin-4-ylmethyl)-1H-indene-2-carboxamide	Investigative	11110049	C20H23N3O	321.4	CN(C)CCNC(=O)C1=C(C2=CC=CC=C2C1)CC3=CC=NC=C3	Ki = 53703.18 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BI25BD	5-(1-Azabicyclo[2.2.1]heptan-3-yl)-1,2,4-oxadiazol-3-amine	Investigative	163938	C8H12N4O	180.21	C1CN2CC1C(C2)C3=NC(=NO3)N	EC50 = 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BI85JF	[(2R,6R)-6-Ethyl-1,4-dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	57326141	C10H22INO2	315.19	CC[C@@H]1COC[C@H](O1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BID3M1	2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl 4-(3-fluorophenyl)-1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575651	C23H24FNO3	381.4	CN1CCC(=C(C1)C(=O)OCCC2=CC3=C(C=C2)OCC3)C4=CC(=CC=C4)F	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BIO5L9	N-Cyclohexyl-2-(4-cyclopentylpiperazin-1-yl)-2-methylpropanamide	Investigative	49853987	C19H35N3O	321.5	CC(C)(C(=O)NC1CCCCC1)N2CCN(CC2)C3CCCC3	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BJDS46	2-(2,4,6-Trimethylphenyl)ethyl 1-ethyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575222	C25H31NO2	377.5	CCN1CCC(=C(C1)C(=O)OCCC2=C(C=C(C=C2C)C)C)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BJEV61	Trimethyl-[[(2R)-5,5,6,6-tetramethyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	46227486	C12H26INO2	343.24	CC1(C(O[C@@H](CO1)C[N+](C)(C)C)(C)C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BK4Q9G	2-(3,4-Dimethoxyphenyl)ethyl 4-(2-methoxyphenyl)-1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574177	C24H29NO5	411.5	CN1CCC(=C(C1)C(=O)OCCC2=CC(=C(C=C2)OC)OC)C3=CC=CC=C3OC	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BKR16E	Trimethyl-[[(2R,6R)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	44446840	C9H20INO2	301.17	C[C@@H]1COC[C@H](O1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BL86PX	[(2R,5R,6S)-5,6-Dimethyl-1,4-dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	46227454	C10H22INO2	315.19	C[C@@H]1[C@@H](O[C@@H](CO1)C[N+](C)(C)C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BM5FV4	2-(4-Cyclohexylpiperazin-1-yl)-2-methyl-N-propan-2-ylpropanamide	Investigative	49853885	C17H33N3O	295.5	CC(C)NC(=O)C(C)(C)N1CCN(CC1)C2CCCCC2	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BMP27U	[(2R)-1,4-Dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	118706054	C8H18INO2	287.14	C[N+](C)(C)C[C@@H]1COCCO1.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BMVB24	Ethyl 1-[1-(2,6-dimethylbenzoyl)piperidin-4-yl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574269	C28H34N2O3	446.6	CCOC(=O)C1=C(CCN(C1)C2CCN(CC2)C(=O)C3=C(C=CC=C3C)C)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BNL89F	Trimethyl-[[(2R,6R)-5,5,6-trimethyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	46227480	C11H24INO2	329.22	C[C@@H]1C(OC[C@H](O1)C[N+](C)(C)C)(C)C.[I-]	Ki = 95499.26 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BNT2J0	Ethyl 1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574268	C23H25NO4	379.4	CCOC(=O)C1=C(CCN(C1)CCC2=CC3=C(C=C2)OCO3)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BO46KV	8-Hydroxy-2-(dimethylamino)-1,2,3,4-tetrahydronaphthalene	Investigative	15629515	C12H17NO	191.27	CN(C)C1CCC2=C(C1)C(=CC=C2)O	Ki ~ 50000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BO61QD	Trimethyl-[[(2R,5S)-5-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	46227410	C9H20INO2	301.17	C[C@H]1CO[C@@H](CO1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BPJR69	Ethyl 1-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574271	C26H32N2O4S	468.6	CCOC(=O)C1=C(CCN(C1)C2CCN(CC2)S(=O)(=O)C3=CC=C(C=C3)C)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BS1D3A	2-(4-Methoxyphenyl)ethyl 1-butyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575339	C25H31NO3	393.5	CCCCN1CCC(=C(C1)C(=O)OCCC2=CC=C(C=C2)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BS9AF4	Trimethyl-[[(2R,6S)-5,5,6-trimethyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	46227460	C11H24INO2	329.22	C[C@H]1C(OC[C@H](O1)C[N+](C)(C)C)(C)C.[I-]	Ki = 67608.3 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BSZ0N4	2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl 2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)benzoate	Investigative	71574367	C23H25NO3	363.4	CN1CCC(=CC1)C2=CC=CC=C2C(=O)OCCC3=CC4=C(C=C3)OCC4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BT0EO7	2-[(8As)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-cyclohexylacetamide	Investigative	49853884	C15H27N3O	265.39	C1CCC(CC1)NC(=O)CN2CCN3CCC[C@H]3C2	IC50 = 50000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BT17YZ	2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl 4-phenyl-1-propyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575448	C25H29NO3	391.5	CCCN1CCC(=C(C1)C(=O)OCCC2=CC3=C(C=C2)OCC3)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BT83FB	(2-Methoxy-2-phenylethyl) 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575554	C22H25NO3	351.4	CN1CCC(=C(C1)C(=O)OCC(C2=CC=CC=C2)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BTF8M9	(5R,2''S)-5-(1-Methyl-2-pyrrolidinyl)oxazolidinone	Investigative	44419370	C8H14N2O2	170.21	CN1CCC[C@H]1[C@H]2CNC(=O)O2	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BTH09U	Trimethyl-[[(2R,3S)-3-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	118723724	C9H20INO2	301.17	C[C@H]1[C@H](OCCO1)C[N+](C)(C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BTHE57	Trimethyl-[[(5R)-3-methyl-2-oxo-1,3-oxazolidin-5-yl]methyl]azanium	Investigative	72545096	C8H17N2O2+	173.23	CN1C[C@@H](OC1=O)C[N+](C)(C)C	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BU57IB	(2R)-2-(Furan-2-yl)-1,1-dimethylpyrrolidin-1-ium;iodide	Investigative	24894634	C10H16INO	293.14	C[N+]1(CCC[C@@H]1C2=CC=CO2)C.[I-]	Ki = 51286.14 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BV0B7Z	Ethyl 4-phenyl-1-(2-phenylethyl)-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71574178	C22H25NO2	335.4	CCOC(=O)C1=C(CCN(C1)CCC2=CC=CC=C2)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BW3N6H	2-(4-Methoxyphenyl)ethyl 4-phenyl-1-propyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575338	C24H29NO3	379.5	CCCN1CCC(=C(C1)C(=O)OCCC2=CC=C(C=C2)OC)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BWBH45	[(2S)-1,1-Dimethylpyrrolidin-1-ium-2-yl]methyl carbamate	Investigative	72545098	C8H17N2O2+	173.23	C[N+]1(CCC[C@H]1COC(=O)N)C	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BWF9Y6	[(2R)-5,5-Dimethyl-1,4-dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	46227458	C10H22INO2	315.19	CC1(CO[C@@H](CO1)C[N+](C)(C)C)C.[I-]	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BX9L7C	2-(Furan-2-yl)pyrrolidine	Investigative	3675988	C8H11NO	137.18	C1CC(NC1)C2=CC=CO2	Ki = 177827.94 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BYF2O7	(2R,5R)-5-[(2S)-1,1-Dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide	Investigative	45266386	C10H20NO2S+	218.34	C[C@@H]1O[C@@H](CS1=O)[C@@H]2CCC[N+]2(C)C	Ki = 93325.43 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BYJ7E6	2-(4-Methylsulfonylphenyl)ethyl 1-ethyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71575121	C23H27NO4S	413.5	CCN1CCC(=C(C1)C(=O)OCCC2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BYTO08	N-Cyclohexyl-2-(4-cyclopentylpiperazin-1-yl)acetamide	Investigative	49853881	C17H31N3O	293.4	C1CCC(CC1)NC(=O)CN2CCN(CC2)C3CCCC3	IC50 ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BYX70W	N-Cyclohexyl-2-(4-methyl-1,4-diazepan-1-yl)acetamide	Investigative	49855131	C14H27N3O	253.38	CN1CCCN(CC1)CC(=O)NC2CCCCC2	IC50 = 102000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BYXU78	(R)-5alpha-[(Dimethylamino)methyl]oxazolidine-2-one	Investigative	57558000	C6H12N2O2	144.17	CN(C)C[C@H]1CNC(=O)O1	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BZ27OF	Ethyl 1-[1-(2,6-dichlorobenzoyl)piperidin-4-yl]-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	Investigative	71717914	C26H28Cl2N2O3	487.4	CCOC(=O)C1=C(CCN(C1)C2CCN(CC2)C(=O)C3=C(C=CC=C3Cl)Cl)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BZ4I0N	(4S)-4-[(2S)-1-Methylpyrrolidin-2-yl]-1,3-oxazolidin-2-one	Investigative	72545326	C8H14N2O2	170.21	CN1CCC[C@H]1[C@H]2COC(=O)N2	Ki ~ 100000 nM	Poor binder
T28893	Muscarinic acetylcholine receptor M1	BZP0V3	[(2R,5R,6R)-5,6-Dimethyl-1,4-dioxan-2-yl]methyl-trimethylazanium;iodide	Investigative	46227414	C10H22INO2	315.19	C[C@@H]1[C@H](O[C@@H](CO1)C[N+](C)(C)C)C.[I-]	Ki ~ 100000 nM	Poor binder