TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T28925	Inosine-5'-monophosphate dehydrogenase	B69MJI	5-Cyanoindole	Investigative	27513	C9H6N2	142.16	C1=CC2=C(C=CN2)C=C1C#N	IC50 = 99000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	B7QW6R	[(2S,3R,4S)-5-(2-Chloro-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Investigative	135976440	C10H12ClN4O8P	382.65	C1=NC2=C(N1C3[C@H]([C@H]([C@@H](O3)COP(=O)(O)O)O)O)N=C(NC2=O)Cl	Ki = 120000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	B8VJ5Z	4-Hydroxycarbazole	Investigative	104251	C12H9NO	183.21	C1=CC=C2C(=C1)C3=C(N2)C=CC=C3O	IC50 = 54000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	BA7TZ8	4-Amino-7-chloroquinoline	Investigative	94711	C9H7ClN2	178.62	C1=CC2=C(C=CN=C2C=C1Cl)N	IC50 = 168000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	BB96LS	[(2S,3R,4S)-3,4-Dihydroxy-5-(6-oxo-2-propyl-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Investigative	135976442	C13H19N4O8P	390.29	CCCC1=NC2=C(C(=O)N1)N=CN2C3[C@H]([C@H]([C@@H](O3)COP(=O)(O)O)O)O	Ki = 190000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	BWA56H	6,7-Dimethyl-4-oxo-2,3-dihydrochromene-3-carbonitrile	Investigative	44291630	C12H11NO2	201.22	CC1=CC2=C(C=C1C)OCC(C2=O)C#N	IC50 = 88000 nM	Poor binder
T28925	Inosine-5'-monophosphate dehydrogenase	D0VD5N	6-Chloropurine Riboside, 5'-Monophosphate	Investigative	188321	C10H12ClN4O7P	366.65	C1=NC2=C(C(=N1)Cl)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	Ki = 62000 nM	Poor binder