TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T30420	SET domain containing 8	B0GHR7	6,7-Dimethoxy-2-piperidin-1-yl-N-(5-pyrrolidin-1-ylpentyl)quinazolin-4-amine	Investigative	118708800	C24H37N5O2	427.6	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCCC3)NCCCCCN4CCCC4)OC	IC50 = 94000 nM	Poor binder
T30420	SET domain containing 8	B1HB3G	2-(3,3-Difluoroazetidin-1-yl)-6,7-dimethoxy-N-(5-pyrrolidin-1-ylpentyl)quinazolin-4-amine	Investigative	122191700	C22H31F2N5O2	435.5	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CC(C3)(F)F)NCCCCCN4CCCC4)OC	IC50 = 110000 nM	Poor binder
T30420	SET domain containing 8	B1LF7K	N-(5-Pyrrolizinopentyl)-2-pyrrolizino-6-methoxy-7-(benzyloxy)quinazoline-4-amine	Investigative	101882837	C29H39N5O2	489.7	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OCC5=CC=CC=C5	IC50 = 130000 nM	Poor binder
T30420	SET domain containing 8	B4N3IO	N-[2-[(6,7-Dimethoxy-2-pyrrolidin-1-ylquinazolin-4-yl)amino]ethyl]-2-pyrrolidin-1-ylacetamide	Investigative	122191697	C22H32N6O3	428.5	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCNC(=O)CN4CCCC4)OC	IC50 = 63000 nM	Poor binder
T30420	SET domain containing 8	B94DLH	5-[(6,7-Dimethoxy-2-pyrrolidin-1-ylquinazolin-4-yl)amino]-1-pyrrolidin-1-ylpentan-1-one	Investigative	118708798	C23H33N5O3	427.5	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCC(=O)N4CCCC4)OC	IC50 = 58000 nM	Poor binder
T30420	SET domain containing 8	BS79KT	N-(5-Pyrrolizinopentyl)-2-pyrrolizino-6-isopropoxy-7-methoxyquinazoline-4-amine	Investigative	101882831	C25H39N5O2	441.6	CC(C)OC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC	IC50 = 61000 nM	Poor binder
T30420	SET domain containing 8	BUJ05C	6,7-Dimethoxy-2-pyrrolidin-1-yl-N-(2-pyrrolidin-1-ylethyl)quinazolin-4-amine	Investigative	118708787	C20H29N5O2	371.5	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCN4CCCC4)OC	IC50 = 67000 nM	Poor binder
T30420	SET domain containing 8	BW9C6Z	N-(5-Pyrrolizinopentyl)-2-pyrrolizino-6-methoxyquinazoline-4-amine	Investigative	101882829	C22H33N5O	383.5	COC1=CC2=C(C=C1)N=C(N=C2NCCCCCN3CCCC3)N4CCCC4	IC50 = 52000 nM	Poor binder