TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31309	Apoptosis regulator Bcl-2	D05TPI	EPICATECHIN	Phase 2	72276	C15H14O6	290.27	C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	D03YSQ	SAR-405838	Phase 1	11512578	C29H35Cl2FN4O3	577.5	CC(C)(C)C[C@@H]1[C@]2([C@H]([C@@H](N1)C(=O)NCCN3CCOCC3)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O	IC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B09CEH	2-[5-(Diphenylmethylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylpentanoic acid	Investigative	44429176	C22H21NO3S2	411.5	CC(C)C[C@@H](C(=O)O)N1C(=O)C(=C(C2=CC=CC=C2)C3=CC=CC=C3)SC1=S	Ki = 57800 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B09XPZ	Apogossypol	Investigative	454878	C28H30O6	462.5	CC1=CC2=C(C(=C(C=C2C(=C1C3=C(C4=CC(=C(C(=C4C=C3C)C(C)C)O)O)O)O)O)O)C(C)C	IC50 = 80000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B10VXS	Antimycin A3	Investigative	245869	C26H36N2O9	520.6	CCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C	Ki = 124000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B26WHV	2-[5-(4-Bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]propanoic acid	Investigative	1555114	C13H10BrNO3S2	372.3	C[C@@H](C(=O)O)N1C(=O)/C(=C/C2=CC=C(C=C2)Br)/SC1=S	Ki = 115000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B29EFZ	(2S)-2-[(4S)-4-[(4-Bromophenyl)methyl]-2,5-dioxoimidazolidin-1-yl]-N-(4-chloro-3-nitrophenyl)sulfonyl-3-phenylpropanamide	Investigative	122194472	C25H20BrClN4O7S	635.9	C1=CC=C(C=C1)C[C@@H](C(=O)NS(=O)(=O)C2=CC(=C(C=C2)Cl)[N+](=O)[O-])N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)Br	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B2MSV9	1-(2-Ethoxyphenyl)-2-[3-methyl-5-oxo-1-(4-phenyl-1,3-thiazol-2-yl)-4H-pyrazol-4-yl]ethane-1,2-dione	Investigative	118734789	C23H19N3O4S	433.5	CCOC1=CC=CC=C1C(=O)C(=O)C2C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B3KE5R	4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitro-N-(4-piperazin-1-ylphenyl)benzenesulfonamide	Investigative	57523431	C28H36N6O4S2	584.8	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)N4CCNCC4)[N+](=O)[O-]	Ki = 138000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B3LXJ5	N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)benzamide	Investigative	16109084	C38H42N6O6S2	742.9	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCC5(CC4)CC(=NO5)C6=CC=CC=C6)[N+](=O)[O-]	EC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B4HW1S	(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-N-(4-methylphenyl)sulfonyl-3-phenylpropanamide	Investigative	122194474	C32H28ClN3O5S	602.1	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B5DX7R	4-[2-(2-Ethoxyphenyl)acetyl]-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)-4H-pyrazol-3-one	Investigative	118734788	C23H21N3O3S	419.5	CCOC1=CC=CC=C1CC(=O)C2C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B5K7LX	(2S)-2-[(4S)-4-[[4-(2-Fluoropyridin-4-yl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoic acid	Investigative	122194468	C24H20FN3O4	433.4	C1=CC=C(C=C1)C[C@@H](C(=O)O)N2C(=O)[C@@H](NC2=O)CC3=CC=C(C=C3)C4=CC(=NC=C4)F	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B7JY4N	4-[(2-Ethoxyphenyl)diazenyl]-2-(3-hydroxy-5-pyridin-4-ylphenyl)-5-methyl-1H-pyrazol-3-one	Investigative	136934825	C23H21N5O3	415.4	CCOC1=CC=CC=C1N=NC2=C(NN(C2=O)C3=CC(=CC(=C3)C4=CC=NC=C4)O)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B7LD0Y	Nvp-cgm097	Investigative	53240420	C38H47ClN4O4	659.3	CC(C)OC1=C(C=C2CC(=O)N([C@H](C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC	IC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B7RXN1	Methyl (2S)-2-[[(2S)-2-[(4S)-4-[[4-(4-chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoyl]amino]-3-phenylpropanoate	Investigative	122193510	C35H32ClN3O5	610.1	COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B7U5SN	(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoic acid	Investigative	122194466	C25H21ClN2O4	448.9	C1=CC=C(C=C1)C[C@@H](C(=O)O)N2C(=O)[C@@H](NC2=O)CC3=CC=C(C=C3)C4=CC=C(C=C4)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B7UND5	(S)-2-[(4S)-4-Benzyl-2,5-dioxoimidazolidin-1-yl]-3-phenylpropionic acid	Investigative	10616967	C19H18N2O4	338.4	C1=CC=C(C=C1)C[C@H]2C(=O)N(C(=O)N2)[C@@H](CC3=CC=CC=C3)C(=O)O	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B81MLE	[4-[[(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoyl]amino]phenyl] acetate	Investigative	122194486	C33H28ClN3O5	582	CC(=O)OC1=CC=C(C=C1)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B84HAK	Methyl (2S)-2-[[(2S)-2-[(4S)-4-[[4-(4-chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoyl]amino]-3-methylbutanoate	Investigative	122194484	C31H32ClN3O5	562.1	CC(C)[C@@H](C(=O)OC)NC(=O)[C@H](CC1=CC=CC=C1)N2C(=O)[C@@H](NC2=O)CC3=CC=C(C=C3)C4=CC=C(C=C4)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B8JDS2	(2S)-2-[(4S)-4-[[4-(3-Methylphenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoic acid	Investigative	122194467	C26H24N2O4	428.5	CC1=CC(=CC=C1)C2=CC=C(C=C2)C[C@H]3C(=O)N(C(=O)N3)[C@@H](CC4=CC=CC=C4)C(=O)O	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B90BWX	Epicatechin	Investigative	1203	C15H14O6	290.27	C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B95VWS	N-[(2-Tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trimethoxyl-5-(2-isopropyl-benzyl)-benzamide	Investigative	16090306	C36H41NO6S	615.8	CC(C)C1=CC=CC=C1CC2=CC(=C(C(=C2OC)OC)OC)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=CC=C4C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B9M2GB	2-[1-Hydroxy-4-(thiophen-2-ylsulfonylamino)naphthalen-2-yl]sulfanylacetic acid	Investigative	1582605	C16H13NO5S3	395.5	C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=CS3	Ki = 54650 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	B9O0ZS	2-[3-(3-Aminophenyl)-5-hydroxyphenyl]-4-[(2-ethoxyphenyl)diazenyl]-5-methyl-1H-pyrazol-3-one	Investigative	136934827	C24H23N5O3	429.5	CCOC1=CC=CC=C1N=NC2=C(NN(C2=O)C3=CC(=CC(=C3)C4=CC(=CC=C4)N)O)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BA1IT6	Chelerythrine chloride	Investigative	72311	C21H18ClNO4	383.8	C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-]	Ki = 171000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BA54QN	4-[(2-Ethoxyphenyl)diazenyl]-2-(3-hydroxy-5-thiophen-2-ylphenyl)-5-methyl-1H-pyrazol-3-one	Investigative	136934826	C22H20N4O3S	420.5	CCOC1=CC=CC=C1N=NC2=C(NN(C2=O)C3=CC(=CC(=C3)C4=CC=CS4)O)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BA5QK1	(2S)-N-(4-Chloro-3-nitrophenyl)sulfonyl-2-[(4S)-4-[[4-(2-fluoropyridin-4-yl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanamide	Investigative	122194483	C30H23ClFN5O7S	652	C1=CC=C(C=C1)C[C@@H](C(=O)NS(=O)(=O)C2=CC(=C(C=C2)Cl)[N+](=O)[O-])N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC(=NC=C5)F	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BE1XN0	(+)-Gallocatechin	Investigative	65084	C15H14O7	306.27	C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BEN90J	5-(4-Bromobenzylidene)-3-(1-morpholino-1-oxo-3-phenylpropan-2-yl)-4-oxo-2-thioxothiazolidine	Investigative	44429179	C17H17BrN2O3S2	441.4	C[C@@H](C(=O)N1CCOCC1)N2C(=O)/C(=C/C3=CC=C(C=C3)Br)/SC2=S	Ki = 70000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BG04EL	Theaflavin digallte	Investigative	44448535	C43H32O20	868.7	C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C(C(=O)C=C(C=C34)C5[C@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O)OC(=O)C8=CC(=C(C(=C8)O)O)O	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BG5FM9	2-[2-[2-[(2S)-2-[(5Z)-5-[(4-Bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoyl]oxyethoxy]ethoxy]ethyl (2S)-2-[(5Z)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoate	Investigative	44456175	C44H38Br2N2O8S4	1010.9	C1=CC=C(C=C1)C[C@H](N2C(=S)S/C(=C\\C3=CC=C(C=C3)Br)/C2=O)C(=O)OCCOCCOCCOC(=O)[C@@H](N4C(=S)S/C(=C\\C5=CC=C(C=C5)Br)/C4=O)CC6=CC=CC=C6	Ki = 161000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BGDX37	(2S)-N-(Benzenesulfonyl)-2-[(4S)-4-[[4-(2-fluoropyridin-4-yl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanamide	Investigative	122194481	C30H25FN4O5S	572.6	C1=CC=C(C=C1)C[C@@H](C(=O)NS(=O)(=O)C2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC(=NC=C5)F	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BGDY13	Spirocyclic Oxazolidin-4-one, 18	Investigative	16109115	C40H46N6O7S2	787	CC1C(=O)N(C2(O1)CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)N[C@H](CCN(C)C)CSC5=CC=CC=C5)[N+](=O)[O-])CC6=CC=CC=C6	EC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BGYO70	Piperazine analogue, 22	Investigative	16109117	C36H41N7O6S2	731.9	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)C(=O)NC5=CC=CC=C5)[N+](=O)[O-]	EC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BHR4B6	(2S)-2-[(4S)-4-[(4-Bromophenyl)methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoic acid	Investigative	122194465	C19H17BrN2O4	417.3	C1=CC=C(C=C1)C[C@@H](C(=O)O)N2C(=O)[C@@H](NC2=O)CC3=CC=C(C=C3)Br	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BIC23E	(2S)-2-[[(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoyl]amino]-3-methylbutanoic acid	Investigative	122194485	C30H30ClN3O5	548	CC(C)[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)N2C(=O)[C@@H](NC2=O)CC3=CC=C(C=C3)C4=CC=C(C=C4)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BKXI13	2-Propenyl 2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-propanoate	Investigative	44429178	C16H14BrNO3S2	412.3	C[C@@H](C(=O)OCC=C)N1C(=O)/C(=C/C2=CC=C(C=C2)Br)/SC1=S	Ki = 192000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BLGH82	Piperazine analogue, 20	Investigative	16109116	C36H40N6O6S2	716.9	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)C(=O)C5=CC=CC=C5)[N+](=O)[O-]	EC50 ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BN82ID	(2S)-2-[(4S)-4-Benzyl-2,5-dioxoimidazolidin-1-yl]-N-(4-chloro-3-nitrophenyl)sulfonyl-3-phenylpropanamide	Investigative	122194470	C25H21ClN4O7S	557	C1=CC=C(C=C1)C[C@H]2C(=O)N(C(=O)N2)[C@@H](CC3=CC=CC=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)Cl)[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BO2B8K	4-[8-Ethylsulfanyl-3-(4-hydroxyphenyl)-3-methyloctan-4-yl]phenol	Investigative	44286285	C23H32O2S	372.6	CCC(C)(C1=CC=C(C=C1)O)C(CCCCSCC)C2=CC=C(C=C2)O	Ki = 169000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BOP73X	(2S)-N-(Benzenesulfonyl)-2-[(4S)-4-[[4-(3-methylphenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanamide	Investigative	122194477	C32H29N3O5S	567.7	CC1=CC(=CC=C1)C2=CC=C(C=C2)C[C@H]3C(=O)N(C(=O)N3)[C@@H](CC4=CC=CC=C4)C(=O)NS(=O)(=O)C5=CC=CC=C5	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BOS5G0	(R)-4-(4-(Dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide	Investigative	11502754	C18H24N4O4S2	424.5	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)N)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BPBR38	4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitro-N-phenylbenzenesulfonamide	Investigative	57523430	C24H28N4O4S2	500.6	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC3=CC=CC=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BPY6T9	4-[4-[[4-[4-(Dimethylamino)-1-hydroxy-1-phenylbutyl]phenoxy]methyl]phenyl]benzoic acid	Investigative	52949336	C32H33NO4	495.6	CN(C)CCCC(C1=CC=CC=C1)(C2=CC=C(C=C2)OCC3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)O)O	Ki = 83000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BQ31WS	(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-N-(4-hydroxyphenyl)-3-phenylpropanamide	Investigative	122193509	C31H26ClN3O4	540	C1=CC=C(C=C1)C[C@@H](C(=O)NC2=CC=C(C=C2)O)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BR3OJ0	4-(4-Chlorophenyl)-1-[(3s)-3,4-Dihydroxybutyl]-N-[3-(4-Methylpiperazin-1-Yl)propyl]-3-Phenyl-1h-Pyrrole-2-Carboxamide	Investigative	57339126	C29H37ClN4O3	525.1	CN1CCN(CC1)CCCNC(=O)C2=C(C(=CN2CC[C@@H](CO)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4	Ki = 78000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BRI6N5	(2S)-N-(Benzenesulfonyl)-2-[(4S)-4-benzyl-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanamide	Investigative	122194469	C25H23N3O5S	477.5	C1=CC=C(C=C1)C[C@H]2C(=O)N(C(=O)N2)[C@@H](CC3=CC=CC=C3)C(=O)NS(=O)(=O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BRU2I4	(2S)-2-[(4S)-4-[[4-(2-Fluoropyridin-4-yl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-N-(4-methylphenyl)sulfonyl-3-phenylpropanamide	Investigative	122194482	C31H27FN4O5S	586.6	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC(=NC=C5)F	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BU1CM9	(2S)-N-(Benzenesulfonyl)-2-[(4S)-4-[(4-bromophenyl)methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanamide	Investigative	122194471	C25H22BrN3O5S	556.4	C1=CC=C(C=C1)C[C@@H](C(=O)NS(=O)(=O)C2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)Br	Ki ~ 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BU61RZ	Epigallocatechin	Investigative	72277	C15H14O7	306.27	C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BUE5J7	4-[(2-Ethoxyphenyl)diazenyl]-2-(3-hydroxy-5-phenylphenyl)-5-methyl-1H-pyrazol-3-one	Investigative	136934824	C24H22N4O3	414.5	CCOC1=CC=CC=C1N=NC2=C(NN(C2=O)C3=CC(=CC(=C3)C4=CC=CC=C4)O)C	Ki ~ 100000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BV07AT	2-[5-(4-Bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylthiobutanoic acid	Investigative	27433194	C15H14BrNO3S3	432.4	CSCC[C@@H](C(=O)O)N1C(=O)/C(=C/C2=CC=C(C=C2)Br)/SC1=S	Ki = 69600 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BV27UD	5-Methyl-N-phenyl-1-(2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide	Investigative	44570077	C27H24N4O2	436.5	CC1=CC(=NN1C2=CC=CC=C2C(=O)N3CCC4=CC=CC=C4C3)C(=O)NC5=CC=CC=C5	IC50 = 50000 nM	Poor binder
T31309	Apoptosis regulator Bcl-2	BZCU01	(2S)-2-[[(2S)-2-[(4S)-4-[[4-(4-Chlorophenyl)phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid	Investigative	122193511	C34H30ClN3O5	596.1	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)N3C(=O)[C@@H](NC3=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder