TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31721	Excitatory amino acid transporter 3	D00ENY	L-Glutamic Acid	Approved	33032	C5H9NO4	147.13	C(CC(=O)O)[C@@H](C(=O)O)N	Ki = 50118.72 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B0IB8U	(1R,2S)-2-[(S)-Amino(carboxy)methyl]-2-methylcyclobutane-1-carboxylic acid	Investigative	73348758	C8H13NO4	187.19	C[C@@]1(CC[C@H]1C(=O)O)[C@@H](C(=O)O)N	Ki = 50118.72 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B1J0VM	2-Amino-4-(4-methoxyphenyl)-5-oxo-7-phenyl-4,6,7,8-tetrahydrochromene-3-carbonitrile	Investigative	2737891	C23H20N2O3	372.4	COC1=CC=C(C=C1)C2C(=C(OC3=C2C(=O)CC(C3)C4=CC=CC=C4)N)C#N	IC50 ~ 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B3ADQ6	L-Serine O-sulfate	Investigative	164701	C3H7NO6S	185.16	C([C@@H](C(=O)O)N)OS(=O)(=O)O	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B5F4OI	(2S,4R)-4-Isopentylglutamic acid	Investigative	11629898	C10H19NO4	217.26	CC(C)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 66069.34 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B6Q5TV	(2S,4S)-4-Isopropylglutamic acid	Investigative	44405320	C8H15NO4	189.21	CC(C)[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 50118.72 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B7HY2T	(2S,4R)-2-Amino-4-[2-(phenylmethoxycarbonylamino)ethyl]pentanedioic acid	Investigative	71574836	C15H20N2O6	324.33	C1=CC=C(C=C1)COC(=O)NCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	B85MTV	(2S)-2-Amino-3-(naphthalen-1-ylsulfonylamino)butanedioic acid	Investigative	134149841	C14H14N2O6S	338.34	C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 63000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BA0T9H	(2S,4R)-4-Butylglutamic acid	Investigative	11651356	C9H17NO4	203.24	CCCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 70794.58 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BAOV94	(2S,4R)-4-Benzylglutamic acid	Investigative	7016554	C12H15NO4	237.25	C1=CC=C(C=C1)C[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 61659.5 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BAV8T1	(1R,2R,5S,6S)-2-Acetyl-2-aminobicyclo[3.1.0]hexane-6-carboxylic acid	Investigative	70682198	C9H13NO3	183.2	CC(=O)[C@]1(CC[C@H]2[C@@H]1[C@H]2C(=O)O)N	IC50 = 53000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BDC30V	(2S)-2-Amino-3-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]butanedioic acid	Investigative	134144947	C10H7F5N2O6S	378.23	C1(=C(C(=C(C(=C1F)F)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)F)F)F	IC50 = 150000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BDK38S	(2S)-2-Amino-3-(benzylsulfonylamino)butanedioic acid	Investigative	134135682	C11H14N2O6S	302.31	C1=CC=C(C=C1)CS(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 75857.76 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BF7AK0	Chembl4161764	Investigative	145958688	C8H13NO5	203.19	C1CC1CO[C@@H]([C@H](C(=O)O)N)C(=O)O	IC50 = 97000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BL38EA	(2S)-2-Amino-3-[[3-(trifluoromethyl)phenyl]sulfonylamino]butanedioic acid	Investigative	134136786	C11H11F3N2O6S	356.28	C1=CC(=CC(=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)C(F)(F)F	IC50 = 150000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BP25UK	(3S)-2-[(4-Acetylphenyl)sulfonylamino]-3-aminobutanedioic acid	Investigative	134140412	C12H14N2O7S	330.32	CC(=O)C1=CC=C(C=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BQHT49	(2S)-2-Amino-3-[[4-(trifluoromethyl)phenyl]sulfonylamino]butanedioic acid	Investigative	134131748	C11H11F3N2O6S	356.28	C1=CC(=CC=C1C(F)(F)F)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BS31QN	2-Amino-4-(4-nitrophenyl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromen-3-yl cyanide	Investigative	2838960	C22H17N3O4	387.4	C1C(CC(=O)C2=C1OC(=C(C2C3=CC=C(C=C3)[N+](=O)[O-])C#N)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BSCD25	(2S)-2-Amino-3-[(4-nitrophenyl)sulfonylamino]butanedioic acid	Investigative	134137403	C10H11N3O8S	333.28	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BSRH61	(2S,4R)-4-Pentylglutamic acid	Investigative	10680281	C10H19NO4	217.26	CCCCC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 87096.36 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BT4Z1N	(2S)-2-Amino-3-[(3,5-dimethylphenyl)sulfonylamino]butanedioic acid	Investigative	134140490	C12H16N2O6S	316.33	CC1=CC(=CC(=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)C	IC50 = 100000 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BU91NF	(2S)-2-Amino-3-(pyridin-3-ylsulfonylamino)butanedioic acid	Investigative	134149576	C9H11N3O6S	289.27	C1=CC(=CN=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 75857.76 nM	Poor binder
T31721	Excitatory amino acid transporter 3	BYV6W8	Cyclobutaneacetic acid, alpha-amino-2-carboxy-, (alphaS,1R,2R)-	Investigative	44417413	C7H11NO4	173.17	C1C[C@H]([C@@H]1[C@@H](C(=O)O)N)C(=O)O	Ki = 50118.72 nM	Poor binder