TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T34296	Matrix metalloproteinase-13	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B0BI8G	N-Methyl-4-(4-methylphenoxy)-N-(pyridin-4-ylmethyl)benzamide	Investigative	56676871	C21H20N2O2	332.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)N(C)CC3=CC=NC=C3	IC50 = 50118.72 nM	Poor binder
T34296	Matrix metalloproteinase-13	B0HYB2	N-(Cyclohexylmethyl)-4-(4-methylphenoxy)benzamide	Investigative	56666624	C21H25NO2	323.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3CCCCC3	IC50 = 50118.72 nM	Poor binder
T34296	Matrix metalloproteinase-13	B0N7VD	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036770	C17H10ClN3OS2	371.9	C1=CC=C(C(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)Cl	IC50 = 89430 nM	Poor binder
T34296	Matrix metalloproteinase-13	B2UFY3	5-[5-[(4-Carboxyphenyl)methylcarbamoyl]-2-methylpyrazol-3-yl]-1H-indole-2-carboxylic acid	Investigative	45377567	C22H18N4O5	418.4	CN1C(=CC(=N1)C(=O)NCC2=CC=C(C=C2)C(=O)O)C3=CC4=C(C=C3)NC(=C4)C(=O)O	IC50 = 56000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B39ANH	Ethyl 5-(methanesulfonamido)-1H-indole-2-carboxylate	Investigative	53957122	C12H14N2O4S	282.32	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)NS(=O)(=O)C	IC50 = 97000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B3Z5RU	(5Z)-5-(3-Phenoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one	Investigative	6005649	C16H11NO2S2	313.4	C1=CC=C(C=C1)OC2=CC=CC(=C2)/C=C\\3/C(=O)NC(=S)S3	IC50 = 55270 nM	Poor binder
T34296	Matrix metalloproteinase-13	B46STP	4-Phenoxy-N-[(1R,2S)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682766	C17H19NO3S2	349.5	C1C[C@H]([C@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B48YSV	US9187406, Curcumin	Investigative	58963267	C21H20O6	368.4	COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)CO)O	IC50 = 110000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B4MG9X	2-(N-Methyl-N-phenylamino)-N-((5-chloro-8-hydroxyquinolin-7-yl)(3-nitrophenyl)methyl)acetamide	Investigative	24958549	C25H21ClN4O4	476.9	CN(CC(=O)NC(C1=CC(=CC=C1)[N+](=O)[O-])C2=CC(=C3C=CC=NC3=C2O)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B4ZP8S	1-[[2-(4-Chlorophenoxy)acetyl]amino]-3-(4-cyclohexylbutyl)thiourea	Investigative	73349535	C19H28ClN3O2S	398	C1CCC(CC1)CCCCNC(=S)NNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B59SNT	Thiadiazole derivative, 34	Investigative	24754251	C24H21N3O2S	415.5	CC1=CC2=C(C=C1)N(C(=O)C23NN=C(S3)C4=CC=C(C=C4)OC)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B5INQ8	3-(1-Phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-2H-chromen-2-one	Investigative	3380837	C18H12N2O2S	320.4	C1=CC=C(C=C1)N2C=C(NC2=S)C3=CC4=CC=CC=C4OC3=O	IC50 = 177000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B5ZP7Q	3-Acetoxy-5-(biphenyl-4-yl)pentanoic acid	Investigative	45482999	C19H20O4	312.4	CC(=O)OC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B62HUJ	(E)-2-(5-((5-(4-Methoxyphenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid	Investigative	2140735	C17H13NO5S2	375.4	COC1=CC=C(C=C1)C2=CC=C(O2)/C=C/3\\C(=O)N(C(=S)S3)CC(=O)O	IC50 = 120000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B8I0RK	Thiadiazole derivative, 35	Investigative	24754252	C24H21N3O2S	415.5	CC1=CC2=C(C=C1)N(C(=O)C23NN=C(S3)C4=CC=C(C=C4)OC)C5=CC=CC=C5C	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B8QGP0	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036769	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)[N+](=O)[O-])/S3	IC50 = 55880 nM	Poor binder
T34296	Matrix metalloproteinase-13	B9FEA2	Furan-2-carboxamide deriv., 18	Investigative	44236904	C26H28N2O4	432.5	CNC(=O)[C@H](C1CCCCC1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)OC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T34296	Matrix metalloproteinase-13	B9JL6Z	4-[[6-(3-Morpholin-4-ylprop-1-ynyl)-4-oxoquinazolin-3-yl]methyl]benzoic acid	Investigative	22712799	C23H21N3O4	403.4	C1COCCN1CC#CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 65000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BC4Q3O	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036783	C18H13N3O3S2	383.4	COC1=C(C=CC(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 67000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 140000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BD2V9Y	N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide	Investigative	54589400	C20H27N5O4	401.5	CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BD3KM6	4-[[4-Oxo-6-(3-phenylpropa-1,2-dienyl)quinazolin-3-yl]methyl]benzoic acid	Investigative	22482219	C25H18N2O3	394.4	C1=CC=C(C=C1)C=C=CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BDW32Q	4-(Benzyloxy)-N-(4-pyridinylmethyl)benzamide	Investigative	2994402	C20H18N2O2	318.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BF6JZ9	CID 66559934	Investigative	66559934	C27H29F3N8O2S3	650.8	C=CCCNC1=NC(=NC(=N1)N2CCC[C@@H]2CNS(=O)(=O)C3=CC=C(C=C3)C(F)(F)F)NCC4=CSC(=N4)C5=CC=CS5	IC50 ~ 50000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BGC4A9	(2S)-2-(Dibenzothiophen-2-ylsulfonylamino)-3-methylbutanoic acid	Investigative	45269911	C17H17NO4S2	363.5	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)SC3=CC=CC=C32	IC50 = 60000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BGN26Y	5-(4-(Benzofuran-2-yl)phenyl)-3-hydroxypentanoic acid	Investigative	45482997	C19H18O4	310.3	C1=CC=C2C(=C1)C=C(O2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 = 50200 nM	Poor binder
T34296	Matrix metalloproteinase-13	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 55000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BIV63S	5-(4''-(Benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483036	C24H24O4	376.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BK5G4F	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814723	C17H11N3O2S2	353.4	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 = 55000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BO81HC	Thiadiazole derivative, 33	Investigative	24754176	C23H19N3O2S	401.5	COC1=CC=C(C=C1)C2=NNC3(S2)C4=CC=CC=C4N(C3=O)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BP6ED9	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036777	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)[N+](=O)[O-])/S3	IC50 = 55880 nM	Poor binder
T34296	Matrix metalloproteinase-13	BRC53V	N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide	Investigative	71682917	C17H19NO4S	333.4	C1C[C@@H]([C@H](C1)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BRLS26	(R)-2-(N-Benzyl-4-(2-fluoroethoxy)phenylsulphonamido)-3-methylbutanoic acid	Investigative	23655717	C20H24FNO5S	409.5	CC(C)[C@H](C(=O)O)N(CC1=CC=CC=C1)S(=O)(=O)C2=CC=C(C=C2)OCCF	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BV84GE	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(2-chlorophenyl)methyl]-2-phenoxyacetamide	Investigative	3671894	C24H18Cl2N2O3	453.3	C1=CC=C(C=C1)OCC(=O)NC(C2=CC=CC=C2Cl)C3=CC(=C4C=CC=NC4=C3O)Cl	IC50 ~ 67000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BVK7H3	4-(2-Phenylethoxy)-N-(pyridin-4-ylmethyl)benzamide	Investigative	56673549	C21H20N2O2	332.4	C1=CC=C(C=C1)CCOC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BWUH98	5-Pyridin-4-yl-1H-indole-2-carboxylic acid ethyl ester	Investigative	56850272	C16H14N2O2	266.29	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CC=NC=C3	IC50 = 82000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BXI61R	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036779	C17H10N4O3S2	382.4	C1=CC=C(C(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)[N+](=O)[O-]	IC50 = 64000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki = 91000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BY4F7G	4-[[4-Oxo-6-(3-piperidin-1-ylprop-1-ynyl)quinazolin-3-yl]methyl]benzoic acid	Investigative	22712801	C24H23N3O3	401.5	C1CCN(CC1)CC#CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 75000 nM	Poor binder
T34296	Matrix metalloproteinase-13	BYMV71	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036767	C17H10ClN3OS2	371.9	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)Cl)/S3	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	D04UBY	5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483018	C18H17NO3	295.3	C1=CC(=CC(=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O)C#N	IC50 = 52000 nM	Poor binder
T34296	Matrix metalloproteinase-13	D0C1EQ	2-(2-(biphenyl-4-yl)ethylthio)acetic acid	Investigative	20348772	C16H16O2S	272.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCSCC(=O)O	IC50 = 95200 nM	Poor binder
T34296	Matrix metalloproteinase-13	D0F4UT	2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid	Investigative	21496278	C16H16O3S	288.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCS(=O)CC(=O)O	IC50 = 95900 nM	Poor binder
T34296	Matrix metalloproteinase-13	D0LB0N	5-(biphenyl-4-yl)-3-oxopentanoic acid	Investigative	45483008	C17H16O3	268.31	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(=O)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T34296	Matrix metalloproteinase-13	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T34296	Matrix metalloproteinase-13	D0TL3N	5-(biphenyl-4-yl)-3-methoxypentanoic acid	Investigative	45482998	C18H20O3	284.3	COC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder