TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T35734	Soluble epoxide hydrolase	D0T5PO	ROLIPRAM	Phase 2	5092	C16H21NO3	275.34	COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B0AKO1	[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-acetic acid	Investigative	44418620	C19H31N3O4	365.5	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)NCC(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B0J1PU	4-Benzyl-1,3-dihydroquinoxalin-2-one	Investigative	759495	C15H14N2O	238.28	C1C(=O)NC2=CC=CC=C2N1CC3=CC=CC=C3	IC50 = 61000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B0Q1ZX	Dibenzyl sulfoxide	Investigative	12116	C14H14OS	230.33	C1=CC=C(C=C1)CS(=O)CC2=CC=CC=C2	IC50 = 70000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B0S9VW	(S)-2-(2-(3-Cyclohexylureido)acetamido)-3-(1H-imidazol-5-yl)propanoic acid	Investigative	44418618	C15H23N5O4	337.37	C1CCC(CC1)NC(=O)NCC(=O)N[C@@H](CC2=CN=CN2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B14HZO	6-{[(Butylamino)carbonyl]amino}nicotinamide	Investigative	16654086	C11H16N4O2	236.27	CCCCNC(=O)NC1=NC=C(C=C1)C(=O)N	IC50 = 57000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B1AU8W	N-Cycloheptyl-1-(4-nitrophenyl)sulfonylpiperidine-4-carboxamide	Investigative	57396878	C19H27N3O5S	409.5	C1CCCC(CC1)NC(=O)C2CCN(CC2)S(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 = 50000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B2B5EL	(S)-2-(2-(3-Cyclohexylureido)acetamido)-3-methylbutanoic acid	Investigative	44418624	C14H25N3O4	299.37	CC(C)[C@@H](C(=O)O)NC(=O)CNC(=O)NC1CCCCC1	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B2H7YP	Chembl4128031	Investigative	145962586	C29H40N2S	448.7	CC(C12CC3CC(C1)CC(C3)C2)NC(=S)NC4=CC=C(C=C4)C56CC7CC(C5)CC(C7)C6	IC50 = 57393 nM	Poor binder
T35734	Soluble epoxide hydrolase	B2PN7X	(S)-2-(2-(3-Cyclohexylureido)acetamido)pentanedioic acid	Investigative	44418617	C14H23N3O6	329.35	C1CCC(CC1)NC(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B35IDB	Chembl4130292	Investigative	145961401	C21H30N2S	342.5	CCC(CC12CC3CC(C1)CC(C3)C2)NC(=S)NC4=CC=CC=C4	IC50 = 50248 nM	Poor binder
T35734	Soluble epoxide hydrolase	B3E1JI	9-Heptadecanone	Investigative	10887	C17H34O	254.5	CCCCCCCCC(=O)CCCCCCCC	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B3I7PL	4-(3-Chloro-phenoxycarbonyloxy)-butyric acid pentyl ester	Investigative	11427448	C16H21ClO5	328.79	CCCCCOC(=O)CCCOC(=O)OC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B3O2FB	N-[2-(Morpholin-4-yl)phenyl]thiophene-3-carboxamide	Investigative	2813415	C15H16N2O2S	288.4	C1COCCN1C2=CC=CC=C2NC(=O)C3=CSC=C3	IC50 = 171000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B4LN7I	Pentyl N-[2-[(3-chlorophenyl)carbamoylamino]ethyl]carbamate	Investigative	11472902	C15H22ClN3O3	327.8	CCCCCOC(=O)NCCNC(=O)NC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B56RJT	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-(4-hydroxy-phenyl)-propionic acid	Investigative	44418706	C26H37N3O5	471.6	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O	IC50 = 80000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B5B8QX	7-Methoxy-2-(trifluoromethyl)-4H-chromen-4-one	Investigative	871502	C11H7F3O3	244.17	COC1=CC2=C(C=C1)C(=O)C=C(O2)C(F)(F)F	IC50 = 91000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B5JOL9	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-hydroxy-propionic acid	Investigative	44418703	C20H33N3O5	395.5	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CO)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B6ANC5	1-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-4-ol	Investigative	2783031	C10H7F3N2O	228.17	C1=CC(=CC(=C1)N2C=C(C=N2)O)C(F)(F)F	IC50 = 52000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B71JVR	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-4-methylsulfanyl-butyric acid	Investigative	44418656	C22H37N3O4S	439.6	CSCC[C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B74KNQ	5-(4-Bromobenzyl)-1,3-thiazol-2-amine	Investigative	727750	C10H9BrN2S	269.16	C1=CC(=CC=C1CC2=CN=C(S2)N)Br	IC50 = 70000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B7IN8J	10-beta-D-Glucopyranosyl-1,8-dihydroxy-3-hydroxymethyl-9(10H)-anthrone	Investigative	9866696	C21H22O9	418.4	C1=CC2=C(C(=C1)O)C(=O)C3=C(C2[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C=C(C=C3O)CO	Ki = 57300 nM	Poor binder
T35734	Soluble epoxide hydrolase	B7T5AH	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-methyl-pentanoic acid	Investigative	44418640	C23H39N3O4	421.6	CCC(C)[C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B7X2AK	(S)-2-[6-(3-Cyclohexyl-ureido)-hexanoylamino]-5-guanidino-pentanoic acid	Investigative	44418646	C19H36N6O4	412.5	C1CCC(CC1)NC(=O)NCCCCCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B8A2XE	4-[2-(3-Chloro-phenyl)-acetoxy]-butyric acid pentyl ester	Investigative	11427381	C17H23ClO4	326.8	CCCCCOC(=O)CCCOC(=O)CC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B8IWY3	(S)-2-(6-(3-Cyclohexylureido)hexanamido)pentanedioic acid	Investigative	44418647	C18H31N3O6	385.5	C1CCC(CC1)NC(=O)NCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	B9E2IR	1-Adamantan-1-yl-3-(2-(3-(piperazin-1-yl)propoxy)phenyl)urea	Investigative	49851180	C24H36N4O2	412.6	C1CN(CCN1)CCCOC2=CC=CC=C2NC(=O)NC34CC5CC(C3)CC(C5)C4	IC50 = 97460 nM	Poor binder
T35734	Soluble epoxide hydrolase	BB2MO3	(4-Bromo-3-cyclopropyl-1H-pyrazol-1-yl)acetic acid	Investigative	19576771	C8H9BrN2O2	245.07	C1CC1C2=NN(C=C2Br)CC(=O)O	IC50 = 91000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BB73CL	N-(1-Adamantyl)piperazine-1-carboxamide	Investigative	28781778	C15H25N3O	263.38	C1CN(CCN1)C(=O)NC23CC4CC(C2)CC(C4)C3	IC50 = 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BCO85M	(S)-2-[2-(3-Cyclohexyl-ureido)-acetylamino]-5-guanidino-pentanoic acid	Investigative	44418616	C15H28N6O4	356.42	C1CCC(CC1)NC(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BD4IK9	1-{2-[3-(3-Chloro-phenyl)-ureido]-ethyl}-3-pentyl-urea	Investigative	11404645	C15H23ClN4O2	326.82	CCCCCNC(=O)NCCNC(=O)NC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BE96HW	(S)-2-((S)-2-(6-(3-Cyclohexylureido)hexanamido)-3-phenylpropanamido)succinic acid	Investigative	44418690	C26H38N4O7	518.6	C1CCC(CC1)NC(=O)NCCCCCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BFZ3Q5	1-Cyclohexyl-3-(2-hydroxymethyl-phenyl)-urea	Investigative	4550519	C14H20N2O2	248.32	C1CCC(CC1)NC(=O)NC2=CC=CC=C2CO	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BGSC94	1-Adamantan-1-yl-3-[2-(4-piperazin-1-yl-butoxy)-phenyl]-urea	Investigative	49851275	C25H38N4O2	426.6	C1CN(CCN1)CCCCOC2=CC=CC=C2NC(=O)NC34CC5CC(C3)CC(C5)C4	IC50 = 72770 nM	Poor binder
T35734	Soluble epoxide hydrolase	BH4K8X	2-Cyclohexyl-N-(2-hydroxymethyl-phenyl)-acetamide	Investigative	11448009	C15H21NO2	247.33	C1CCC(CC1)CC(=O)NC2=CC=CC=C2CO	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BI3H4R	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-propionic acid	Investigative	44418634	C20H33N3O4	379.5	C[C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BIN08Q	1-(2,6-Diisopropyl-phenyl)-3-[4-(4-fluoro-phenoxy)-cyclohexyl]-urea	Investigative	44419715	C25H33FN2O2	412.5	CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NC2CCC(CC2)OC3=CC=C(C=C3)F	IC50 = 50500 nM	Poor binder
T35734	Soluble epoxide hydrolase	BJ4FI2	(S)-2-(2-(3-Cyclohexylureido)acetamido)-3-phenylpropanoic acid	Investigative	44418623	C18H25N3O4	347.4	C1CCC(CC1)NC(=O)NCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BJ5AN4	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-4-methyl-pentanoic acid	Investigative	44418655	C23H39N3O4	421.6	CC(C)C[C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BK4D0H	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-(3H-imidazol-4-yl)-propionic acid	Investigative	44418639	C23H35N5O4	445.6	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CC4=CN=CN4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BKQ65Z	13-(2-(n-Butylamino)-2-oxoacetamido)tridec-8(Z)-enoic acid	Investigative	44234918	C19H34N2O4	354.5	CCCCNC(=O)C(=O)NCCCC/C=C\\CCCCCCC(=O)O	IC50 = 58712 nM	Poor binder
T35734	Soluble epoxide hydrolase	BLE56G	Methyl 2-(3-cyclohexylureido)acetate	Investigative	11053022	C10H18N2O3	214.26	COC(=O)CNC(=O)NC1CCCCC1	IC50 = 70000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BMIG86	(S)-2-((S)-2-(6-(3-Cyclohexylureido)hexanamido)-3-phenylpropanamido)pentanedioic acid	Investigative	44418691	C27H40N4O7	532.6	C1CCC(CC1)NC(=O)NCCCCCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BN36QF	Chembl4203677	Investigative	145978702	C37H56O10	660.8	C[C@@H]1C[C@@H]2[C@@H](O[C@]3([C@H]1[C@]4(CC[C@@]56C[C@@]57CC[C@@H](C([C@@H]7CC=C6[C@@]4([C@H]3O)C)(C)C)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)OC(=O)C)C)O2)C(C)(C)O	IC50 = 60900 nM	Poor binder
T35734	Soluble epoxide hydrolase	BN62OX	Methyl (1S)-7,8,9-trihydroxy-3,5-dioxo-1,2-dihydrocyclopenta[c]isochromene-1-carboxylate	Investigative	90654762	C14H10O8	306.22	COC(=O)[C@H]1CC(=O)C2=C1C3=C(C(=C(C=C3C(=O)O2)O)O)O	IC50 ~ 50000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BN8AW1	N-[2-[(3-Chlorophenyl)carbamoylamino]ethyl]heptanamide	Investigative	11484196	C16H24ClN3O2	325.83	CCCCCCC(=O)NCCNC(=O)NC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BN9Q4U	2-(Pyridin-3-yl)-1H-benzo[d]imidazole	Investigative	247635	C12H9N3	195.22	C1=CC=C2C(=C1)NC(=N2)C3=CN=CC=C3	IC50 = 91000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BNQC06	3-(4-(Benzyloxy)phenyl)propan-1-ol	Investigative	2764076	C16H18O2	242.31	C1=CC=C(C=C1)COC2=CC=C(C=C2)CCCO	IC50 = 150000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BO2I3L	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-5-guanidino-pentanoic acid	Investigative	44418648	C23H40N6O4	464.6	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BOA78G	1-(2,6-Dichlorophenyl)-3-(1-propionylpiperidin-4-yl)urea	Investigative	49783425	C15H19Cl2N3O2	344.2	CCC(=O)N1CCC(CC1)NC(=O)NC2=C(C=CC=C2Cl)Cl	IC50 ~ 50000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BP6X2U	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-methyl-butyric acid	Investigative	44418707	C22H37N3O4	407.5	CC(C)[C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2	IC50 = 55000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BQ7BI5	6-[(Adamantan-1-ylcarbamoyl)amino]hexanoic acid	Investigative	25093349	C17H28N2O3	308.4	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BR13TU	2-(4-Methoxyphenyl)imidazo[1,2-a]pyridine	Investigative	694963	C14H12N2O	224.26	COC1=CC=C(C=C1)C2=CN3C=CC=CC3=N2	IC50 = 75000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BR75DF	4-(3-Chloro-phenoxycarbonylamino)-butyric acid pentyl ester	Investigative	11186477	C16H22ClNO4	327.8	CCCCCOC(=O)CCCNC(=O)OC1=CC(=CC=C1)Cl	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BS30QW	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-3-hydroxy-butyric acid	Investigative	44418704	C21H35N3O5	409.5	CC([C@@H](C(=O)O)NC(=O)CCCCCNC(=O)NC12CC3CC(C1)CC(C3)C2)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BS4JB1	(S)-2-(6-(3-Cyclohexylureido)hexanamido)-3-(1H-imidazol-5-yl)propanoic acid	Investigative	44418653	C19H31N5O4	393.5	C1CCC(CC1)NC(=O)NCCCCCC(=O)N[C@@H](CC2=CN=CN2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BS73VB	2-(Furan-2-yl)benzo[d]oxazole	Investigative	938024	C11H7NO2	185.18	C1=CC=C2C(=C1)N=C(O2)C3=CC=CO3	IC50 = 133000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BS95OZ	(S)-1-[6-(3-Adamantan-1-yl-ureido)-hexanoyl]-pyrrolidine-2-carboxylic acid	Investigative	44418605	C22H35N3O4	405.5	C1C[C@H](N(C1)C(=O)CCCCCNC(=O)NC23CC4CC(C2)CC(C4)C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BSN96Y	Di-n-octyl Sulfone	Investigative	3798558	C16H34O2S	290.5	CCCCCCCCS(=O)(=O)CCCCCCCC	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BV8D3L	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-succinic acid	Investigative	44418649	C21H33N3O6	423.5	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BWL03N	Dioctyl sulfide	Investigative	75901	C16H34S	258.5	CCCCCCCCSCCCCCCCC	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BWT0P3	2-(1-Methyl-1H-pyrazol-4-yl)-1H-benzimidazole	Investigative	16227558	C11H10N4	198.22	CN1C=C(C=N1)C2=NC3=CC=CC=C3N2	IC50 = 127000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BWU51T	4-[2,5-Dimethyl-1-(tetrahydrofuran-2-ylmethyl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine	Investigative	4463317	C14H19N3OS	277.39	CC1=CC(=C(N1CC2CCCO2)C)C3=CSC(=N3)N	IC50 = 195000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BXWM21	(S)-2-[6-(3-Adamantan-1-yl-ureido)-hexanoylamino]-pentanedioic acid	Investigative	44418619	C22H35N3O6	437.5	C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BZK24Y	N-Cyclohexyl-2-(2-hydroxymethyl-phenyl)-acetamide	Investigative	11265133	C15H21NO2	247.33	C1CCC(CC1)NC(=O)CC2=CC=CC=C2CO	IC50 ~ 100000 nM	Poor binder
T35734	Soluble epoxide hydrolase	BZKX43	Methyl 3-[(cyclohexylcarbamoyl)amino]propanoate	Investigative	11020645	C11H20N2O3	228.29	COC(=O)CCNC(=O)NC1CCCCC1	IC50 = 78000 nM	Poor binder
T35734	Soluble epoxide hydrolase	D08BFU	ASTRAGALIN	Investigative	5282102	C21H20O11	448.4	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O	IC50 ~ 50000 nM	Poor binder
T35734	Soluble epoxide hydrolase	D09BUG	Aloe-emodin	Investigative	10207	C15H10O5	270.24	C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO	Ki = 52200 nM	Poor binder