TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39677	Bile-salt-activated lipase	B29LPH	2-(2,3,4,5,6-Pentafluorophenyl)-4,5,6,7-tetrahydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide	Investigative	44561932	C13H8F5NO3S	353.27	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=C(C(=C(C(=C3F)F)F)F)F	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	B36ZIR	2-(6-Bromopyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide	Investigative	44561892	C12H11BrN2O3S	343.2	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=NC(=CC=C3)Br	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	B3KYM0	4,5-Dimethyl-2-(2,3,5,6-tetrafluoropyridin-4-yl)-isothiazol-3(2H)-one 1,1-dioxide	Investigative	44561930	C10H6F4N2O3S	310.23	CC1=C(S(=O)(=O)N(C1=O)C2=C(C(=NC(=C2F)F)F)F)C	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	B4ADZ2	2-(2,3,5,6-Tetrafluoropyridin-4-yl)-4,5,6,7-tetrahydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide	Investigative	25141405	C12H8F4N2O3S	336.26	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=C(C(=NC(=C3F)F)F)F	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	B7PMG1	2-(6-Chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide	Investigative	44561891	C12H11ClN2O3S	298.75	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=NC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	B8RS5T	1,1-Dioxo-2-pyridin-4-yl-4,5,6,7-tetrahydro-1,2-benzothiazol-3-one;perchloric acid	Investigative	49797481	C12H13ClN2O7S	364.76	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=CC=NC=C3.OCl(=O)(=O)=O	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	BEB9O5	5-Methyl-4-phenyl-2-(2,3,5,6-tetrafluoropyridin-4-yl)-isothiazol-3(2H)-one 1,1-dioxide	Investigative	44561931	C15H8F4N2O3S	372.3	CC1=C(C(=O)N(S1(=O)=O)C2=C(C(=NC(=C2F)F)F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T39677	Bile-salt-activated lipase	BX0G5F	2-(3,5-Difluoropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide	Investigative	44561893	C12H10F2N2O3S	300.28	C1CCC2=C(C1)C(=O)N(S2(=O)=O)C3=C(C=C(C=N3)F)F	IC50 ~ 100000 nM	Poor binder