TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39977	Macrophage migration inhibitory factor	B02VAF	3-[3-[3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanoic acid	Investigative	45268613	C15H14FN3O5	335.29	COC1=C(C=C(C=C1)C2=NOC(C2)C3=NOC(=N3)CCC(=O)O)F	IC50 = 60000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B12EWT	2-[[2-Chloro-5-[(4-fluorophenyl)sulfamoyl]benzoyl]amino]benzoic acid	Investigative	1105140	C20H14ClFN2O5S	448.9	C1=CC=C(C(=C1)C(=O)O)NC(=O)C2=C(C=CC(=C2)S(=O)(=O)NC3=CC=C(C=C3)F)Cl	IC50 = 74490 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B15JTN	N-((3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)methyl)-3-methylbutanamide	Investigative	136123462	C15H19FN2O3	294.32	CC(C)CC(=O)NCC1CC(=NO1)C2=CC(=C(C=C2)O)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B2GS3D	(3R)-3-(Furan-2-yl)-4-phenylbutanoic acid	Investigative	807516	C14H14O3	230.26	C1=CC=C(C=C1)C[C@H](CC(=O)O)C2=CC=CO2	IC50 = 85560 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B39XSH	2-[(4-Hydroxy-benzylidene)-amino]-3-(1H-indol-3-yl)-propionic acid methyl ester	Investigative	136110959	C19H18N2O3	322.4	COC(=O)[C@@H](CC1=CNC2=CC=CC=C21)N=CC3=CC=C(C=C3)O	IC50 ~ 50000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B3WK6N	2-[(4-Hydroxy-benzylidene)-amino]-4-methyl-pentanoic acid methyl ester	Investigative	135512729	C14H19NO3	249.3	CC(C)C[C@@H](C(=O)OC)N=CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B41HQM	4-(1-Isothiocyanatopropyl)phenol	Investigative	16007100	C10H11NOS	193.27	CCC(C1=CC=C(C=C1)O)N=C=S	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B45NAS	3-Nitroso-2-phenylindolizine	Investigative	3748059	C14H10N2O	222.24	C1=CC=C(C=C1)C2=C(N3C=CC=CC3=C2)N=O	IC50 = 120800 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B47EGW	4-(4-(3,4-Dimethoxybenzyl)-1H-1,2,3-triazol-1-yl)phenol	Investigative	52942373	C17H17N3O3	311.33	COC1=C(C=C(C=C1)CC2=CN(N=N2)C3=CC=C(C=C3)O)OC	IC50 = 70000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B4KU7Z	N-((3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)methyl)pivalamide	Investigative	135965914	C15H19FN2O3	294.32	CC(C)(C)C(=O)NCC1CC(=NO1)C2=CC(=C(C=C2)O)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B51UGF	3-(3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydroisoxazol-5-yl)-5-(trifluoromethyl)-1,2,4-oxadiazole	Investigative	45273787	C13H9F4N3O3	331.22	COC1=C(C=C(C=C1)C2=NOC(C2)C3=NOC(=N3)C(F)(F)F)F	IC50 = 95000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B5AS3T	3-(1H-Pyrazol-4-yl)benzoic Acid	Investigative	7174253	C10H8N2O2	188.18	C1=CC(=CC(=C1)C(=O)O)C2=CNN=C2	Ki = 113000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B5H1YX	Benzyl thiocyanate	Investigative	18170	C8H7NS	149.21	C1=CC=C(C=C1)CSC#N	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B5QTA0	3-[(2-Methyl-6-Phenylpyridin-4-Yl)oxy]phenol	Investigative	71462587	C18H15NO2	277.3	CC1=CC(=CC(=N1)C2=CC=CC=C2)OC3=CC=CC(=C3)O	Ki = 101000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B6PZR2	3-((3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)methyl)-1,1-dimethylurea	Investigative	135965945	C13H16FN3O3	281.28	CN(C)C(=O)NCC1CC(=NO1)C2=CC(=C(C=C2)O)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B7Z5MI	[(E)-(4-Hydroxyphenyl)methylideneamino] 2,2-dimethylpropanoate	Investigative	136036592	C12H15NO3	221.25	CC(C)(C)C(=O)O/N=C/C1=CC=C(C=C1)O	IC50 = 113000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	B96CGW	2-[(4-Hydroxy-benzylidene)-amino]-butyric acid methyl ester	Investigative	135442230	C12H15NO3	221.25	CC[C@@H](C(=O)OC)N=CC1=CC=C(C=C1)O	IC50 = 70000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BA6Q4C	N-(Furan-2-ylmethyl)-7-nitro-2,1,3-benzoxadiazol-4-amine	Investigative	2821653	C11H8N4O4	260.209	C1=COC(=C1)CNC2=CC=C(C3=NON=C23)[N+](=O)[O-]	IC50 = 60400 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BC6EF7	4-Hydroxy-2-[(4-hydroxy-benzylidene)-amino]-butyric acid methyl ester	Investigative	135544543	C12H15NO4	237.25	COC(=O)[C@H](CCO)N=CC1=CC=C(C=C1)O	IC50 = 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BD49NY	2-Fluoro-4-(5-(5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl)-4,5-dihydroisoxazole-3-yl)phenol	Investigative	135966018	C12H7F4N3O3	317.2	C1C(ON=C1C2=CC(=C(C=C2)O)F)C3=NOC(=N3)C(F)(F)F	IC50 = 60000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BDB58W	4-Oxo-4-((4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)amino)butanoic acid	Investigative	866325	C16H12N2O5S	344.3	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CSC(=N3)NC(=O)CCC(=O)O	IC50 = 102120 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BE9AF2	3-((3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydroisoxazol-5-yl)methyl)-5-(trifluoromethyl)-1,2,4-oxadiazole	Investigative	45268606	C14H11F4N3O3	345.25	COC1=C(C=C(C=C1)C2=NOC(C2)CC3=NOC(=N3)C(F)(F)F)F	IC50 = 55000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BEB92W	Methyl 3-[3-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]propanoate	Investigative	136123460	C15H14FN3O5	335.29	COC(=O)CCC1=NC(=NO1)C2CC(=NO2)C3=CC(=C(C=C3)O)F	IC50 = 50000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BEI28R	3-(2-Isothiocyanatoethyl)phenol	Investigative	84105925	C9H9NOS	179.24	C1=CC(=CC(=C1)O)CCN=C=S	IC50 = 62000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BFQ01W	4-(4-(4-Methoxybenzyl)-1H-1,2,3-triazol-1-yl)phenol	Investigative	52948461	C16H15N3O2	281.31	COC1=CC=C(C=C1)CC2=CN(N=N2)C3=CC=C(C=C3)O	IC50 = 65000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BH1Y2T	3-Benzoyl-7-hydroxy-2H-chromen-2-one	Investigative	5413038	C16H10O4	266.25	C1=CC=C(C=C1)C(=O)C2=CC3=C(C=C(C=C3)O)OC2=O	IC50 = 64200 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BHRK68	Phenethyl isocyanate	Investigative	160602	C9H9NO	147.17	C1=CC=C(C=C1)CCN=C=O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BIYT48	2-(3-(3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydroisoxazol-5-yl)-1,2,4-oxadiazol-5-yl)phenyl(methyl)carbamic acid	Investigative	45270304	C20H17FN4O5	412.4	CN(C1=CC=CC=C1C2=NC(=NO2)C3CC(=NO3)C4=CC(=C(C=C4)OC)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BJW9C3	Methyl-2-(4-hydroxybenzylidene)hydrazinecarboxylate	Investigative	135581769	C9H10N2O3	194.19	COC(=O)N/N=C/C1=CC=C(C=C1)O	IC50 = 55000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BMA54R	N-Cyclohexyl-3-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazole-5-yl)-1,2,4-oxadiazol-5-yl)propanamide	Investigative	136123459	C20H23FN4O4	402.4	C1CCC(CC1)NC(=O)CCC2=NC(=NO2)C3CC(=NO3)C4=CC(=C(C=C4)O)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BMHZ48	Ethyl 2-cyano-3-(2,4-dihydroxyphenyl)acrylate	Investigative	794467	C12H11NO4	233.22	CCOC(=O)/C(=C/C1=C(C=C(C=C1)O)O)/C#N	IC50 = 62100 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BNCV34	2-[(4-Hydroxy-benzylidene)-amino]-3-phenyl-propionic acid methyl ester	Investigative	136110958	C17H17NO3	283.32	COC(=O)[C@@H](CC1=CC=CC=C1)N=CC2=CC=C(C=C2)O	IC50 = 50000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BNDY64	3-(3-(3-Fluoro-4-methoxyphenyl)-4,5-dihydroisoxazole-5-yl)-5-methyl-1,2,4-oxadiazole	Investigative	45270292	C13H12FN3O3	277.25	CC1=NC(=NO1)C2CC(=NO2)C3=CC(=C(C=C3)OC)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BR63AX	2-Fluoro-4-[5-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]methyl]-4,5-dihydro-1,2-oxazol-3-yl]phenol	Investigative	135965940	C13H9F4N3O3	331.22	C1C(ON=C1C2=CC(=C(C=C2)O)F)CC3=NOC(=N3)C(F)(F)F	IC50 = 60000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BRW2F4	N-(4-Aminobutyl)-2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetamide	Investigative	136043748	C15H21N3O3	291.35	C1C(ON=C1C2=CC=C(C=C2)O)CC(=O)NCCCCN	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BRZT63	4-[(4-Hydroxyphenyl)-isothiocyanatomethyl]phenol	Investigative	118731500	C14H11NO2S	257.31	C1=CC(=CC=C1C(C2=CC=C(C=C2)O)N=C=S)O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BSR3D5	2-Fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-dihydroisoxazol-3-yl)phenol	Investigative	135965910	C12H10FN3O3	263.22	CC1=NC(=NO1)C2CC(=NO2)C3=CC(=C(C=C3)O)F	IC50 = 60000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BT5RE2	Benzhydryl isothiocyanate	Investigative	520742	C14H11NS	225.31	C1=CC=C(C=C1)C(C2=CC=CC=C2)N=C=S	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BTL5O6	(5-Methyl-2-propan-2-ylphenyl) 2-[3-(4-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]acetate	Investigative	57392315	C22H25NO4	367.4	CC1=CC(=C(C=C1)C(C)C)OC(=O)CC2CC(=NO2)C3=CC=C(C=C3)OC	IC50 = 55300 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BU86YP	2-[(4-Hydroxy-benzylidene)-amino]-5-methylsulfanyl-pentanoic acid methyl ester	Investigative	135542501	C14H19NO3S	281.37	COC(=O)[C@H](CCCSC)N=CC1=CC=C(C=C1)O	IC50 = 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BVI9C0	[(E)-(4-Hydroxyphenyl)methylideneamino] acetate	Investigative	136036593	C9H9NO3	179.17	CC(=O)O/N=C/C1=CC=C(C=C1)O	IC50 = 147000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BW8T3D	2,2,2-Trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)ethyl)acetamide	Investigative	135966020	C13H12F4N2O3	320.24	C1C(ON=C1C2=CC(=C(C=C2)O)F)CCNC(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BY65LF	2-[(4-Hydroxy-benzylidene)-amino]-propionic acid methyl ester	Investigative	135501601	C11H13NO3	207.23	C[C@@H](C(=O)OC)N=CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BY72NH	1-(2-(3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)ethyl)pyrrolidine-2,5-dione	Investigative	135965913	C15H15FN2O4	306.29	C1CC(=O)N(C1=O)CCC2CC(=NO2)C3=CC(=C(C=C3)O)F	IC50 = 50000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BYR50N	3-[3-[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]-1,2,4-oxadiazol-5-yl]benzene-1,2-diol	Investigative	136123500	C17H12FN3O5	357.29	C1C(ON=C1C2=CC(=C(C=C2)O)F)C3=NOC(=N3)C4=C(C(=CC=C4)O)O	IC50 ~ 100000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	BZ07YE	3-Fluorobenzyl isothiocyanate	Investigative	2737275	C8H6FNS	167.21	C1=CC(=CC(=C1)F)CN=C=S	IC50 = 54000 nM	Poor binder
T39977	Macrophage migration inhibitory factor	D09BVA	3-acetyl-7-hydroxy-2H-chromen-2-one	Investigative	5392139	C11H8O4	204.18	CC(=O)C1=CC2=C(C=C(C=C2)O)OC1=O	IC50 = 103200 nM	Poor binder