TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T40016	Glucocorticoid receptor	D0V9BD	Bicalutamide	Approved	2375	C18H14F4N2O4S	430.4	CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T40016	Glucocorticoid receptor	B0LD7O	24-Phenethyl-3alpha,7beta-dihydroxy-5beta-cholanamide	Investigative	49652409	C32H49NO3	495.7	C[C@H](CCC(=O)NCCC1=CC=CC=C1)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H](C[C@H]5[C@@]4(CC[C@H](C5)O)C)O)C	EC50 = 109000 nM	Poor binder
T40016	Glucocorticoid receptor	B0SB6C	3alpha,7beta-Dihydroxy-5-beta-cholan-24-nitrile	Investigative	50993355	C24H39NO2	373.6	C[C@H](CCC#N)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 = 101000 nM	Poor binder
T40016	Glucocorticoid receptor	B7KSU8	3alpha,7beta-Dihydroxy-24-bisnor-5beta-cholane-22-nitrile	Investigative	52943487	C22H35NO2	345.5	C[C@H](C#N)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 = 130000 nM	Poor binder
T40016	Glucocorticoid receptor	B82PVM	1-(2-Phenoxyethyl)-3-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-imine	Investigative	1043068	C22H28N4O	364.5	C1CCN(CC1)CCN2C3=CC=CC=C3N(C2=N)CCOC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T40016	Glucocorticoid receptor	BAIL56	24-alpha-Methylbenzyl-3alpha,7beta-dihydroxy-5beta-cholanamide	Investigative	50993282	C32H49NO3	495.7	C[C@H](CCC(=O)NC(C)C1=CC=CC=C1)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H](C[C@H]5[C@@]4(CC[C@H](C5)O)C)O)C	EC50 = 123500 nM	Poor binder
T40016	Glucocorticoid receptor	BD06KA	(5s)-2-{[(1s)-1-(2-Fluorophenyl)ethyl]amino}-5-Methyl-5-(Trifluoromethyl)-1,3-Thiazol-4(5h)-One	Investigative	135513268	C13H12F4N2OS	320.31	C[C@@H](C1=CC=CC=C1F)N=C2NC(=O)[C@@](S2)(C)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T40016	Glucocorticoid receptor	BD35TU	N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide	Investigative	135459005	C18H13BrN2O3	385.2	C1=CC=C2C=C(C(=CC2=C1)C(=O)N/N=C/C3=C(C=CC(=C3)Br)O)O	IC50 ~ 100000 nM	Poor binder
T40016	Glucocorticoid receptor	BH0KO4	24-Piperazine-3alpha,7beta-dihydroxy-5beta-cholanamide	Investigative	50993208	C28H48N2O3	460.7	C[C@H](CCC(=O)N1CCNCC1)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H](C[C@H]5[C@@]4(CC[C@H](C5)O)C)O)C	EC50 = 50800 nM	Poor binder
T40016	Glucocorticoid receptor	BJ90IG	24-Benzyl-3alpha,7beta-hydroxy-5beta-cholanamide	Investigative	49652111	C31H47NO3	481.7	C[C@H](CCC(=O)NCC1=CC=CC=C1)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H](C[C@H]5[C@@]4(CC[C@H](C5)O)C)O)C	EC50 = 109500 nM	Poor binder
T40016	Glucocorticoid receptor	BKH2C9	(2R,5S)-4-[4-Cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(trifluoromethyl)pyridin-3-yl]piperazine-1-carboxamide	Investigative	11155655	C21H19F6N5O	471.4	C[C@@H]1CN([C@H](CN1C(=O)NC2=CN=C(C=C2)C(F)(F)F)C)C3=CC(=C(C=C3)C#N)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T40016	Glucocorticoid receptor	BLCW02	Norursodeoxycholic Acid	Investigative	192254	C23H38O4	378.5	C[C@H](CC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 = 105300 nM	Poor binder
T40016	Glucocorticoid receptor	BO8F2X	Sundaicumone A	Investigative	11585049	C32H50O9	578.7	CCCC(CC(=O)O)C1=C2[C@]3(C[C@@H](C([C@@](C1=O)(C3=O)C(=O)C(C)CC)(C)C)CC(C(C)(C)O)O)C[C@H](O2)C(C)(C)O	EC50 = 173000 nM	Poor binder
T40016	Glucocorticoid receptor	BR4B3J	Dinorursodeoxycholic acid	Investigative	11143041	C22H36O4	364.5	C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C)C(=O)O	EC50 = 99700 nM	Poor binder
T40016	Glucocorticoid receptor	BZ82YS	Sundaicumone B	Investigative	11504875	C32H48O7	544.7	CCCC(CC(=O)O)C1=C2[C@]3(C[C@@H](C([C@@](C1=O)(C3=O)C(=O)C(C)CC)(C)C)CC=C(C)C)C[C@H](O2)C(C)(C)O	EC50 = 75000 nM	Poor binder
T40016	Glucocorticoid receptor	BZ8FY4	N'-[(E)-(4-Hydroxy-3,5-dimethoxyphenyl)methylidene]naphtho[2,1-b]furan-2-carbohydrazide	Investigative	135571931	C22H18N2O5	390.4	COC1=CC(=CC(=C1O)OC)/C=N/NC(=O)C2=CC3=C(O2)C=CC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T40016	Glucocorticoid receptor	D00DNY	Ellipticine	Investigative	3213	C17H14N2	246.31	CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C	IC50 = 90000 nM	Poor binder
T40016	Glucocorticoid receptor	D0T4SL	9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole	Investigative	72512	C18H16N2O	276.3	CC1=C2C=CN=CC2=C(C3=C1NC4=C3C=C(C=C4)OC)C	IC50 = 90000 nM	Poor binder