TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T40097	Stress-activated protein kinase JNK1	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B0BQ9J	3-(Pyridin-4-yl)-4-(quinolin-6-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	942437	C16H11N5S	305.4	C1=CC2=C(C=CC(=C2)N3C(=NNC3=S)C4=CC=NC=C4)N=C1	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B0REW7	4-(Naphthalen-2-yl)-3-(2-(thiazol-2-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317414	C20H14N6OS	386.4	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC(=NC=C4)NC5=NC=CS5	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B19QVJ	4-(5-(Naphthalen-2-yl)-1H-tetrazol-1-yl)pyridine	Investigative	54581363	C16H11N5	273.29	C1=CC=C2C=C(C=CC2=C1)C3=NN=NN3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B1RS9X	4-(Naphthalen-2-yl)-3-(pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317412	C17H12N4O	288.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B2KUP5	4-Amino-2-ethoxy-6-(2-phenylethylamino)pyridine-3-carbonitrile	Investigative	70687106	C16H18N4O	282.34	CCOC1=C(C(=CC(=N1)NCCC2=CC=CC=C2)N)C#N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B2MZA8	2-(2-(Naphthalen-1-yl)acetamido)thiophene-3-carboxylic acid	Investigative	54580142	C17H13NO3S	311.4	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=C(C=CS3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B2QYF7	Methyl 5-(2-(naphthalen-1-yl)acetamido)-1,2,3-thiadiazole-4-carboxylate	Investigative	52947399	C16H13N3O3S	327.4	COC(=O)C1=C(SN=N1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B3D7GA	2-(2-(Pyren-1-yl)acetamido)thiophene-3-carboxamide	Investigative	54587045	C23H16N2O2S	384.5	C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CC(=O)NC5=C(C=CS5)C(=O)N	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B49TDI	4-(Pyrrolo[1,2-a]quinoxalin-4-ylamino)cyclohexan-1-ol	Investigative	72163958	C17H19N3O	281.35	C1CC(CCC1NC2=NC3=CC=CC=C3N4C2=CC=C4)O	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B4TK6V	N-(4-Methylpyridin-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52944962	C18H16N2O	276.3	CC1=C(C=NC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B4ZA2H	3-(2-Methylpyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585286	C17H13N5S	319.4	CC1=NC=CC(=C1)C2=NNC(=S)N2C3=CC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B56ZJM	3-(2-Methylpyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585285	C18H14N4S	318.4	CC1=NC=CC(=C1)C2=NNC(=S)N2C3=CC4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B5IKG2	Ac-RPTTLNL-OH	Investigative	44585591	C37H65N11O12	856	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)C)O	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B69XRH	Methyl 4-(2-(naphthalen-1-yl)acetamido)thiazole-5-carboxylate	Investigative	52947421	C17H14N2O3S	326.4	COC(=O)C1=C(N=CS1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B6HLJ3	2-(2-Morpholinoacetamido)thiophene-3-carboxamide	Investigative	8903993	C11H15N3O3S	269.32	C1COCCN1CC(=O)NC2=C(C=CS2)C(=O)N	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B73GAO	2-(3-Phenylpropanamido)thiophene-3-carboxamide	Investigative	2970548	C14H14N2O2S	274.34	C1=CC=C(C=C1)CCC(=O)NC2=C(C=CS2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B7O8WI	Ethyl 3-methyl-5-(2-(naphthalen-1-yl)acetamido)isothiazole-4-carboxylate	Investigative	52946172	C19H18N2O3S	354.4	CCOC(=O)C1=C(SN=C1C)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B7TBU2	3-(2-(Cyclohexylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54581360	C23H23N5S	401.5	C1CCC(CC1)NC2=NC=CC(=C2)C3=NNC(=S)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B80VYD	4-(4-(Naphthalen-2-yl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54581361	C17H12N4	272.3	C1=CC=C2C=C(C=CC2=C1)N3C=NN=C3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B8C2IQ	4-(Naphthalen-2-yl)-5-(pyridin-4-yl)pyrimidine	Investigative	54585292	C19H13N3	283.3	C1=CC=C2C=C(C=CC2=C1)C3=NC=NC=C3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B8N4TK	7-Chloro-1-(3,4-dichlorophenyl)-6-methoxy-3,4-dihydroisoquinoline	Investigative	44138048	C16H12Cl3NO	340.6	COC1=C(C=C2C(=C1)CCN=C2C3=CC(=C(C=C3)Cl)Cl)Cl	IC50 = 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B8OU7F	Chembl4290513	Investigative	145988888	C24H20BrN3O2S	494.4	C1COC2=C(O1)C=CC(=C2)C3CC(=NN3C(=S)NC4=CC=CC=C4)C5=CC=C(C=C5)Br	IC50 = 93600 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B8P7TM	2-(2-(Perfluorophenyl)acetamido)thiophene-3-carboxamide	Investigative	17496132	C13H7F5N2O2S	350.27	C1=CSC(=C1C(=O)N)NC(=O)CC2=C(C(=C(C(=C2F)F)F)F)F	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B91ICA	4-(4-Chloro-5-(naphthalen-2-yl)-1H-1,2,3-triazol-1-yl)pyridine	Investigative	54583368	C17H11ClN4	306.7	C1=CC=C2C=C(C=CC2=C1)C3=C(N=NN3C4=CC=NC=C4)Cl	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B91WLR	N-(3-Cyanothiophen-2-yl)-2-(naphthalen-1-yl)acetamide	Investigative	2137680	C17H12N2OS	292.4	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=C(C=CS3)C#N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B92DQV	4-(5-(Naphthalen-2-yl)-1H-1,2,3-triazol-1-yl)pyridine	Investigative	54585290	C17H12N4	272.3	C1=CC=C2C=C(C=CC2=C1)C3=CN=NN3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B93WOZ	2-{[2-(Diethylamino)pyrimidin-4-yl]amino}benzoic acid	Investigative	23647249	C15H18N4O2	286.33	CCN(CC)C1=NC=CC(=N1)NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	B9KAJ3	N-Ethyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232313	C7H7N5O2S3	289.4	CCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 = 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BA4H0M	2-(2-(4-(2-(Trifluoromethyl)phenylsulfonyl)piperazin-1-yl)acetamido)thiophene-3-carboxamide	Investigative	16231644	C18H19F3N4O4S2	476.5	C1CN(CCN1CC(=O)NC2=C(C=CS2)C(=O)N)S(=O)(=O)C3=CC=CC=C3C(F)(F)F	IC50 = 75100 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BBA31U	N-[4-(4-Naphthalen-2-yl-5-oxo-1H-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide	Investigative	53317415	C24H17N5O2	407.4	C1=CC=C(C=C1)C(=O)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BCZ2E3	3-(Pyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54581359	C16H11N5S	305.4	C1=CC=C2C(=C1)C=C(C=N2)N3C(=NNC3=S)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BDH69C	3-(3-Fluoropyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54587258	C17H11FN4S	322.4	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=S)C4=C(C=NC=C4)F	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BF3T7C	4-(5-Chloro-4-(naphthalen-2-yl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54584316	C17H11ClN4	306.7	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3Cl)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BG05CP	N-(3-Aminopropyl)-4-(1H-indazol-3-yl)benzamide	Investigative	56658172	C17H18N4O	294.35	C1=CC=C2C(=C1)C(=NN2)C3=CC=C(C=C3)C(=O)NCCCN	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BG7J3V	4-(5-Hydrazono-4-(naphthalen-2-yl)-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyridine	Investigative	54587260	C17H14N6	302.33	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3NN)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BGK7I9	4-(2,5-Dihydro-1H-imidazo[1,2-a]quinoxalin-4-ylideneamino)cyclohexan-1-ol	Investigative	136252684	C16H20N4O	284.36	C1CC(CCC1N=C2C3=NCCN3C4=CC=CC=C4N2)O	IC50 = 73000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BH0V2B	4-(1-(Naphthalen-2-yl)-1H-1,2,3-triazol-5-yl)pyridine	Investigative	54587261	C17H12N4	272.3	C1=CC=C2C=C(C=CC2=C1)N3C(=CN=N3)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BI91UH	4-(4-(Naphthalen-2-yl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54585289	C18H11F3N4	340.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3C(F)(F)F)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BIO97D	2-Cinnamamidothiophene-3-carboxamide	Investigative	6104220	C14H12N2O2S	272.32	C1=CC=C(C=C1)/C=C/C(=O)NC2=C(C=CS2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BK01JP	2-(2-(4-(Cyclopropanecarbonyl)piperazin-1-yl)acetamido)thiophene-3-carboxamide	Investigative	17551446	C15H20N4O3S	336.4	C1CC1C(=O)N2CCN(CC2)CC(=O)NC3=C(C=CS3)C(=O)N	IC50 = 83500 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BMDO73	4-(1-(Naphthalen-2-yl)-1H-tetrazol-5-yl)pyridine	Investigative	54586233	C16H11N5	273.29	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=N3)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BME3S2	5-(2-(Naphthalen-1-yl)acetamido)thiophene-2-carboxamide	Investigative	54585083	C17H14N2O2S	310.4	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=CC=C(S3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BNLC90	2-(2-(Biphenyl-4-yl)acetamido)thiophene-3-carboxamide	Investigative	2128371	C19H16N2O2S	336.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CC(=O)NC3=C(C=CS3)C(=O)N	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BNM0W7	3-(2-(Cyclopropylmethylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54584315	C21H19N5S	373.5	C1CC1CNC2=NC=CC(=C2)C3=NNC(=S)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BP3CX9	Methyl 2-(2-(naphthalen-1-yl)acetamido)nicotinate	Investigative	52947422	C19H16N2O3	320.3	COC(=O)C1=C(N=CC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BQ03TJ	2-(2-(2,6-Dimethylmorpholino)acetamido)thiophene-3-carboxamide	Investigative	16230198	C13H19N3O3S	297.38	CC1CN(CC(O1)C)CC(=O)NC2=C(C=CS2)C(=O)N	IC50 = 65300 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BQY6Z2	7-Chloro-1-(3-chlorophenyl)-6-methoxy-3,4-dihydroisoquinoline	Investigative	44138049	C16H13Cl2NO	306.2	COC1=C(C=C2C(=C1)CCN=C2C3=CC(=CC=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BRDF65	Methyl 4-(2-(naphthalen-1-yl)acetamido)-1,2,5-oxadiazole-3-carboxylate	Investigative	52942532	C16H13N3O4	311.29	COC(=O)C1=NON=C1NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BU4G7R	4-(4-(4-Fluorophenyl)-2-(4-methylcyclohexyl)-1H-imidazol-5-yl)pyridine	Investigative	44576212	C21H22FN3	335.4	CC1CCC(CC1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F	IC50 = 175000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BUEM67	Chembl4294787	Investigative	145993502	C31H27N3O3S	521.6	C1COC2=C(O1)C=CC(=C2)C3CC(=NN3C(=S)NC4=CC=CC=C4)C5=CC=C(C=C5)OCC6=CC=CC=C6	IC50 = 88900 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BV42JX	4-(1-(Naphthalen-2-yl)-1H-imidazol-2-yl)pyridine	Investigative	54583369	C18H13N3	271.3	C1=CC=C2C=C(C=CC2=C1)N3C=CN=C3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BV56IY	4-(5-Methyl-4-(naphthalen-2-yl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54587259	C18H14N4	286.3	CC1=NN=C(N1C2=CC3=CC=CC=C3C=C2)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BVUN20	4-(1-(Naphthalen-2-yl)-1H-pyrazol-5-yl)pyridine	Investigative	54581362	C18H13N3	271.3	C1=CC=C2C=C(C=CC2=C1)N3C(=CC=N3)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BWM8U7	2-(2-Naphthylacetylamino)benzamide	Investigative	905354	C19H16N2O2	304.3	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=CC=CC=C3C(=O)N	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BWXT95	2-(4-Methoxyphenyl)-N-(2-(2-oxooxazolidin-3-yl)thiophen-3-yl)acetamide	Investigative	52942482	C16H16N2O4S	332.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)N3CCOC3=O	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BWY8V1	2-{[2-(Hexyloxy)pyrimidin-4-yl]amino}benzoic acid	Investigative	23647242	C17H21N3O3	315.37	CCCCCCOC1=NC=CC(=N1)NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BXUQ08	3-(2-(Cyclopentylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53322644	C22H21N5O	371.4	C1CCC(C1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BZ21PQ	3-(2-Bromopyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585287	C17H11BrN4S	383.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=S)C4=CC(=NC=C4)Br	IC50 ~ 50000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	BZ8KY0	Methyl 2-(2-(naphthalen-1-yl)acetamido)thiophene-3-carboxylate	Investigative	7164065	C18H15NO3S	325.4	COC(=O)C1=C(SC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T40097	Stress-activated protein kinase JNK1	D06LJL	PMID16451062C46	Investigative	9916282	C29H33FN6O4S	580.7	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=NC=C(S3)CC(=O)NC4=CC(=CC=C4)F)OCCCN5CCC(CC5)CO	IC50 ~ 100000 nM	Poor binder