TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T41702 Casein kinase I gamma-1 B2T0RU CID 46179972 Investigative 46179972 C28H31N6O3 499.6 CC1(CC(CC(N1[O])(C)C)NC(=O)C2=CC=CC(=C2)C3=NN4C(=CC=NC4=C3)NC5=CC(=CC=C5)O)C IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 B3T9QN Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate Investigative 44219749 C24H29N7O5 495.5 COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5 IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 B5NSE7 4-(4-Methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile Investigative 45375865 C28H28N6O2S 512.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C)C#N IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 BA62QX 4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile Investigative 24766030 C24H21N5OS 427.5 CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5 IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 BIKV80 3-[[2-(2-Fluorophenyl)pyridin-4-yl]amino]-4-[[(1R)-1-phenylethyl]amino]cyclobut-3-ene-1,2-dione Investigative 44575073 C23H18FN3O2 387.4 C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CC=C4F IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 BMP0C7 Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate Investigative 44605037 C25H33N7O3 479.6 CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5 IC50 ~ 50000 nM Poor binder T41702 Casein kinase I gamma-1 BMTS94 6-Methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile Investigative 45375866 C29H30N6O2S 526.7 CC1=C(C=CC2=C1C=CN2)NC3=C(C(=NC=C3C#N)C)/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C IC50 ~ 50000 nM Poor binder