TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T42247	Melanoma inhibitor of apoptosis protein	B2IPM7	(S)-N-((S)-2-((S)-2-(4-(Benzo[d]isoxazol-3-yl)thiazol-2-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46884477	C26H33N5O3S	495.6	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C4=NOC5=CC=CC=C54)NC	Ki = 130000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B2TP9F	(S)-N-((S)-2-((S)-2-(4-(Benzofuran-3-yl)thiazol-2-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46884476	C27H34N4O3S	494.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C4=COC5=CC=CC=C54)NC	Ki = 200000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B4IE5S	N-{(1s)-1-Cyclohexyl-2-Oxo-2-[(2s)-2-(4-Phenyl-1,3-Benzothiazol-2-Yl)pyrrolidin-1-Yl]ethyl}-N~2~-Methyl-L-Alaninamide	Investigative	44820627	C29H36N4O2S	504.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CC=CC=C5)NC	Ki = 53000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B5T1AS	(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluoronaphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46884436	C29H35FN4O2S	522.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C4=CC=C(C5=CC=CC=C54)F)NC	Ki = 68000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B6F3IG	(2S)-N-((1S)-2-((2S)-2-(5-Ethynyl-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide	Investigative	46883825	C30H34N4O3S	530.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=C(S3)C#C)C4=CC=CC5=CC=CC=C54)NC	Ki = 160000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B7JBN9	(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(3-fluorophenyl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46883994	C29H35FN4O2S	522.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CC(=CC=C5)F)NC	Ki = 130000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B7SUF8	(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((S)-2-(4-(pyridin-3-yl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)ethyl)-2-(methylamino)propanamide	Investigative	46883921	C28H35N5O2S	505.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CN=CC=C5)NC	Ki = 200000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B8USO4	(2S)-N-((1S)-2-((2S)-2-(5-(3-Hydroxyprop-1-ynyl)-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide	Investigative	46883828	C31H36N4O4S	560.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=C(S3)C#CCO)C4=CC=CC5=CC=CC=C54)NC	Ki = 140000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	B9RA7N	(S)-N-((S)-2-((S)-2-(4-(4-Chlorophenyl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46883992	C29H35ClN4O2S	539.1	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CC=C(C=C5)Cl)NC	Ki = 68000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BD72AJ	(S)-N-((S)-1-((S)-2-(4-(Benzo[b]thiophen-3-yl)thiazol-2-yl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2-(methylamino)propanamide	Investigative	46884520	C25H32N4O2S2	484.7	C[C@@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C2=NC(=CS2)C3=CSC4=CC=CC=C43)C(C)(C)C)NC	Ki = 120000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BF0YI8	(2S)-N-((1S)-1-Cyclohexyl-2-((2S)-2-(4-(2-fluorophenyl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46883993	C29H35FN4O2S	522.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CC=CC=C5F)NC	Ki = 130000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BF78XP	(2S)-N-((1S)-2-((2S)-2-(5-(3-Methoxyprop-1-ynyl)-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide	Investigative	46883827	C32H38N4O4S	574.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=C(S3)C#CCOC)C4=CC=CC5=CC=CC=C54)NC	Ki = 140000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BFU10L	(S)-N-((S)-2-((S)-2-(4-(3-Chlorophenyl)benzo[d]thiazol-2-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)-2-(methylamino)propanamide	Investigative	46883924	C29H35ClN4O2S	539.1	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(C=CC=C4S3)C5=CC(=CC=C5)Cl)NC	Ki = 140000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BI6X7Y	(S)-N-((S)-3,3-Dimethyl-1-oxo-1-((S)-2-(4-(quinolin-4-yl)thiazol-2-yl)pyrrolidin-1-yl)butan-2-yl)-2-(methylamino)propanamide	Investigative	46884475	C26H33N5O2S	479.6	C[C@@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C2=NC(=CS2)C3=CC=NC4=CC=CC=C34)C(C)(C)C)NC	Ki = 180000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BLH1J7	(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((S)-2-(7-phenylthiazolo[5,4-d]pyrimidin-2-yl)pyrrolidin-1-yl)ethyl)-2-(methylamino)propanamide	Investigative	46830176	C27H34N6O2S	506.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC4=C(N=CN=C4S3)C5=CC=CC=C5)NC	Ki = 130000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BNUX63	(2S)-2-(Methylamino)-N-((1S)-2-((2S)-2-(4-(naphthalen-1-yl)-5-(prop-1-ynyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)propanamide	Investigative	46883826	C31H36N4O3S	544.7	CC#CC1=C(N=C(S1)[C@@H]2CCCN2C(=O)[C@H](C3CCOCC3)NC(=O)[C@H](C)NC)C4=CC=CC5=CC=CC=C54	Ki = 160000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BP0JF3	(S)-2-(Methylamino)-N-((S)-2-((S)-2-(4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)propanamide	Investigative	46884435	C28H34N4O3S	506.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C4=CC=CC5=CC=CC=C54)NC	Ki = 100000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BR7HJ9	(2S)-N-((1S)-2-((2S)-2-(5-Cyano-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide	Investigative	46884523	C29H33N5O3S	531.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=C(S3)C#N)C4=CC=CC5=CC=CC=C54)NC	Ki = 69000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BV8S9A	(2S)-N-((1S)-2-((2S)-2-(5-Fluoro-4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide	Investigative	46884521	C28H33FN4O3S	524.7	C[C@@H](C(=O)N[C@@H](C1CCOCC1)C(=O)N2CCC[C@H]2C3=NC(=C(S3)F)C4=CC=CC5=CC=CC=C54)NC	Ki = 68000 nM	Poor binder
T42247	Melanoma inhibitor of apoptosis protein	BZWE03	N-{(1s)-1-Cyclohexyl-2-[(2s)-2-(4-Naphthalen-1-Yl-1,3-Thiazol-2-Yl)pyrrolidin-1-Yl]-2-Oxoethyl}-N~2~-Methyl-L-Alaninamide	Investigative	44820626	C29H36N4O2S	504.7	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C4=CC=CC5=CC=CC=C54)NC	Ki = 110000 nM	Poor binder