TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T44861	Protein kinase C delta	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	D0E6XR	Dasatinib	Approved	3062316	C22H26ClN7O2S	488	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	D0WS1V	L-751250	Preclinical	448991	C20H25ClN6O3	432.9	CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=C(C=C3)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	B19FWG	(3E)-5-(2,2-Dimethylpropoxymethyl)-5-(hydroxymethyl)-3-[5-methyl-3-(2-methylpropyl)hexylidene]oxolan-2-one	Investigative	11624847	C22H40O4	368.5	CC(C)CC(C/C=C/1\\CC(OC1=O)(CO)COCC(C)(C)C)CC(C)C	Ki = 101000 nM	Poor binder
T44861	Protein kinase C delta	B2U1HJ	1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	4877	C19H19N5	317.4	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=CC4=CC=CC=C43)N	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	B3RAE6	3-(5-Chloro-2-{[1-(dimethylamino)propan-2-yl]oxy}phenyl)-1-(5-cyanopyrazin-2-yl)urea	Investigative	11417488	C17H19ClN6O2	374.8	CC(CN(C)C)OC1=C(C=C(C=C1)Cl)NC(=O)NC2=NC=C(N=C2)C#N	IC50 = 50000 nM	Poor binder
T44861	Protein kinase C delta	B5S3GE	N-Benzoyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273619	C30H23N5O2	485.5	CC1=C(C=C(C=C1)N(C(=O)C2=CC=CC=C2)C(=O)C3=CC=CC=C3)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	B6J9NQ	4-Pyridin-4-yl-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine	Investigative	9799152	C17H12F4N4O	364.3	C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	B7X8DU	N-[4-Chloro-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273476	C22H16ClN5O	401.8	C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	B90MKA	(+)-(1R,3R)-1-(3-Hydroxy-cyclopentyl)-3-(4-methoxy-phenyl)-7-phenylamino-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one	Investigative	9910609	C24H25N5O3	431.5	COC1=CC=C(C=C1)N2CC3=CN=C(N=C3N(C2=O)[C@@H]4CC[C@H](C4)O)NC5=CC=CC=C5	IC50 ~ 125000 nM	Poor binder
T44861	Protein kinase C delta	B9IKV3	4-(2-(5-Cyano-4-(4-methyl-1H-indol-5-ylamino)pyridin-3-yl)vinyl)-N,N-dipropylbenzenesulfonamide	Investigative	46879558	C29H31N5O2S	513.7	CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)/C=C/C2=CN=CC(=C2NC3=C(C4=C(C=C3)NC=C4)C)C#N	IC50 = 51000 nM	Poor binder
T44861	Protein kinase C delta	BAX6F9	3-{5-Chloro-2-[(3-methyloxetan-3-yl)methoxy]phenyl}-1-(5-cyanopyrazin-2-yl)urea	Investigative	11406175	C17H16ClN5O3	373.8	CC1(COC1)COC2=C(C=C(C=C2)Cl)NC(=O)NC3=NC=C(N=C3)C#N	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	BC8XV0	[4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine	Investigative	19966997	C18H12ClF4N3O	397.8	C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BE63UG	4,N*1*-Dimethyl-N*3*-(4-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine	Investigative	44273595	C17H17N5	291.35	CC1=C(C=C(C=C1)NC)NC2=NC=CC(=N2)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BGR68O	N-[4-Methoxy-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273659	C23H19N5O2	397.4	COC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BI0J6M	4-Chloro-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	9953676	C23H18ClN5O	415.9	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)Cl)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BI2VA4	3-[4-(4-Hydroxyphenyl)phenyl]-N-(pyridin-4-ylmethyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide	Investigative	136060555	C29H22N4O2	458.5	C1C2=C(C=CC(=C2)C(=O)NCC3=CC=NC=C3)C4=C1C(=NN4)C5=CC=C(C=C5)C6=CC=C(C=C6)O	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	BIR3H1	3-(4'-Hydroxybiphenyl-4-Yl)-N-(4-Hydroxycyclohexyl)-1,4-Dihydroindeno[1,2-C]pyrazole-6-Carboxamide	Investigative	135589980	C29H27N3O3	465.5	C1CC(CCC1NC(=O)C2=CC3=C(C=C2)C4=C(C3)C(=NN4)C5=CC=C(C=C5)C6=CC=C(C=C6)O)O	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	BLY8I6	8-Decyl-5-hydroxymethyl-2-isopropyl-1-methyl-1,2,5,6-tetrahydro-benzo[e][1,4]oxazocin-3-one	Investigative	10894726	C25H41NO3	403.6	CCCCCCCCCCC1=CC2=C(C=C1)N([C@H](C(=O)O[C@@H](C2)CO)C(C)C)C	Ki = 70600 nM	Poor binder
T44861	Protein kinase C delta	BO6AK2	4-(1-Methyl-1H-indol-5-ylamino)-5-styrylnicotinonitrile	Investigative	45485046	C23H18N4	350.4	CN1C=CC2=C1C=CC(=C2)NC3=C(C=NC=C3/C=C/C4=CC=CC=C4)C#N	IC50 = 64000 nM	Poor binder
T44861	Protein kinase C delta	BQ15CD	N-{4-Methyl-3-[4-(1-oxy-pyridin-3-yl)-pyrimidin-2-ylamino]-phenyl}-benzamide	Investigative	44273555	C23H19N5O2	397.4	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=C[N+](=CC=C4)[O-]	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BQ9Y5W	2-[9-(4-Amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)acetamide	Investigative	44427518	C32H31N5O4	549.6	COC1=C(C=CC(=C1)C2=CC3=C(C=C2)C(=O)NC4=C(N3)C=CC(=C4)CC(=O)NC5=CC=C(C=C5)N6CCOCC6)N	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	BSR32G	(3Z)-6-(4-Hydroxy-3-methoxyphenyl)-3-(1H-imidazol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one	Investigative	135678111	C19H15N3O3	333.3	COC1=C(C=CC(=C1)C2=CC3=C(C=C2)/C(=C/C4=NC=CN4)/C(=O)N3)O	IC50 ~ 50000 nM	Poor binder
T44861	Protein kinase C delta	BUD4J7	N-[4-Methyl-3-(4-thiophen-2-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273554	C22H18N4OS	386.5	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BUY1S6	Purvalanol A	Investigative	456214	C19H25ClN6O	388.9	CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BX9B7G	N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273559	C24H21N5O	395.5	CC1=C(C=C(C=C1)N(C)C(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BZAD41	3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid	Investigative	10039959	C16H12N4O2	292.29	C1=CC(=CC(=C1)NC2=NC=CC(=N2)C3=CN=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	BZNF82	2-Methoxy-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	10136330	C24H21N5O2	411.5	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2OC)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	D02XHC	aloisine A	Investigative	448912	C16H17N3O	267.33	CCCCC1=C(NC2=NC=CN=C12)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T44861	Protein kinase C delta	D09XIL	Ro-4396686	Investigative	11396738	C24H24FN5O3	449.5	COC1=CC=C(C=C1)N2CC3=CN=C(N=C3N(C2=O)[C@@H]4CC[C@H](C4)O)NC5=CC=C(C=C5)F	IC50 ~ 125000 nM	Poor binder
T44861	Protein kinase C delta	D0D6DH	A-432411	Investigative	10125830	C20H16N2O3	332.4	COC1=C(C=CC(=C1)C2=CC3=C(C=C2)/C(=C/C4=CC=CN4)/C(=O)N3)O	IC50 ~ 50000 nM	Poor binder