TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T44991	Vascular cell adhesion protein 1	D0H2DQ	Probucol	Approved	4912	C31H48O2S2	516.799	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	B0FNI5	Hexafluoropentanedioic acid 1-[2,6-di-tert-butyl-4-[1-methyl-1-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylthio]phenyl] ester	Investigative	44319200	C36H48F6O5S2	738.9	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OC(=O)C(C(C(C(=O)O)(F)F)(F)F)(F)F)C(C)(C)C	IC50 = 100000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	B0SE2P	N-(4-Chlorophenyl)-4-(4-methylphenyl)sulfanylthieno[2,3-c]pyridine-2-carboxamide	Investigative	9953413	C21H15ClN2OS2	410.9	CC1=CC=C(C=C1)SC2=C3C=C(SC3=CN=C2)C(=O)NC4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	B30NWJ	Probucol Disuccinate	Investigative	9961854	C39H56O8S2	717	CC(C)(C)C1=CC(=CC(=C1OC(=O)CCC(=O)O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OC(=O)CCC(=O)O)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	B3MEX5	4-(2-Pyridinylthio)thieno[2,3-c]pyridine-2-carboxamide	Investigative	9882382	C13H9N3OS2	287.4	C1=CC=NC(=C1)SC2=C3C=C(SC3=CN=C2)C(=O)N	IC50 = 65000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	B4OYG8	6-Ethylthieno[2,3-d]pyrimidin-4(3H)-one	Investigative	645569	C8H8N2OS	180.23	CCC1=CC2=C(S1)N=CNC2=O	IC50 ~ 100000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	BHLK68	5-Hydroxyvaleric acid 2,6-di-tert-butyl-4-[1-methyl-1-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylthio]phenyl ester	Investigative	44319652	C36H56O4S2	617	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OC(=O)CCCCO)C(C)(C)C	IC50 = 55000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	BT5K0A	Oxalic acid 1-[2,6-di-tert-butyl-4-[1-methyl-1-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylthio]phenyl] ester	Investigative	44319255	C33H48O5S2	588.9	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OC(=O)C(=O)O)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	BU69HG	3,3-Dimethyl-4-hydroxybutyric acid 2,6-di-tert-butyl-4-[1-methyl-1-(3,5-di-tert-butyl-4-hydroxyphenylthio)ethylthio]phenyl ester	Investigative	44319601	C37H58O4S2	631	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OC(=O)CC(C)(C)CO)C(C)(C)C	IC50 = 110000 nM	Poor binder
T44991	Vascular cell adhesion protein 1	BV2K9A	N-Benzyl-6-ethylthieno[2,3-d]pyrimidin-4-amine	Investigative	745480	C15H15N3S	269.4	CCC1=CC2=C(N=CN=C2S1)NCC3=CC=CC=C3	IC50 = 59000 nM	Poor binder