TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T46482	Toll-like receptor 7	B0HCK7	CU-CPT17e	Investigative	132585194	C27H24N2O8	504.5	C1COCCC12C=CC3=CC(=C(C=C3O2)OCC4=CC=C(C=C4)[N+](=O)[O-])OCC5=CC=C(C=C5)[N+](=O)[O-]	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B0JKO7	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)occcccn	Investigative	122510278	C28H38N6O3	506.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CN=C3)OCCCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B0P7ZI	Chembl4284645	Investigative	137515383	C21H21N5OS	391.5	CCN1C(=NC2=C1C3=C(C=C(C=C3)C4=CC=CS4)N=C2N)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B0PO5D	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)cccn	Investigative	122510309	C26H34N6O2	462.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B1CV4Q	Chembl4288029	Investigative	137516341	C24H21N7O	423.5	C1[C@H](CN(C1=O)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)N5C=CC=N5)N)C6=CC=CC=C6	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B1JNL2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)cccn	Investigative	122510283	C27H35N5O2	461.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)CCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B1KQ4C	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccco)C=CC(=C2)C(=O)NC=1C=NC=CC=1	Investigative	122510326	C23H27N5O3	421.5	CCCN(CCCO)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC=C3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B1WRQ7	2-Amino-N8-[3-(5-aminopentyl)phenyl]-N4,N4-dipropyl-3H-1-benzazepine-4,8-dicarboxamide	Investigative	122510263	C29H39N5O2	489.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CCCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B1ZX8K	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccccccn	Investigative	122510239	C29H40N6O2	504.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCCCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B21KJI	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)OC	Investigative	122510307	C25H30N4O3	434.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC=C3)OC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B28ESU	Chembl4282327	Investigative	130454467	C24H32N6O4S	500.6	CN(C)C1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)S(=O)(=O)N(C)C)OC)OCC4=CC=CC=C4	IC50 = 52000 nM	Poor binder
T46482	Toll-like receptor 7	B2B8HQ	4-Amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol	Investigative	130714	C14H16N4O	256.3	CC(C)(CN1C=NC2=C1C3=CC=CC=C3N=C2N)O	EC50 = 95000 nM	Poor binder
T46482	Toll-like receptor 7	B2BGO7	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)cccccn	Investigative	122510343	C29H39N5O2	489.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)CCCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B2K7FE	1-[2-(Ethylaminomethyl)imidazo[4,5-c]quinolin-3-yl]-2-methylpropan-2-ol	Investigative	44138041	C17H22N4O	298.4	CCNCC1=NC2=C(N1CC(C)(C)O)C=NC3=CC=CC=C32	IC50 = 56310 nM	Poor binder
T46482	Toll-like receptor 7	B2OYN1	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1SC=CN=1	Investigative	122510242	C21H25N5O2S	411.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=NC=CS3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B2U3KZ	NC1=NC2=C(C=C(C1)C(=O)N(CC#C)Ccc)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510375	C25H26N4O2	414.5	CCCN(CC#C)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B2W5RQ	NC1=NC2=C(C=C(C1)C(=O)N(Cco)cccc)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510261	C25H30N4O3	434.5	CCCCN(CCO)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B35QVN	Chembl4278564	Investigative	137515794	C21H21N5O	359.4	CCN(CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CC=CC=C4)N)C(=O)C	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B37YUL	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)C	Investigative	122510329	C25H30N4O2	418.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B39KHR	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccc1=CC=C(C=C1)OC	Investigative	122510264	C32H37N5O3	539.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCC4=CC=C(C=C4)OC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B3IXJ4	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)F	Investigative	122510370	C24H27FN4O2	422.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)F)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B3VR8Z	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)cccccn	Investigative	122510232	C28H38N6O2	490.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B3W5BE	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccccn	Investigative	122510247	C27H36N6O2	476.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B43XLI	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)cccoccoccn)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510376	C29H39N5O4	521.7	CCCN(CCCOCCOCCN)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B45BSK	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)CN	Investigative	122510277	C24H30N6O2	434.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B4QZV6	C(C1=CC=CC=C1)OC(Ncc=1C=NC=C(C=1)NC(=O)C1=CC2=C(C=C(CC(=N2)N)C(N(ccc)ccc)=O)C=C1)=O	Investigative	122510354	C32H36N6O4	568.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CNC(=O)OCC4=CC=CC=C4)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B4X1ZB	Chembl4290288	Investigative	137515213	C22H21N5O	371.4	CC1=CC(=CC=C1)C2=CC3=C(C=C2)C4=C(C(=N3)N)NC(=N4)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B5XI0D	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=NC=C1	Investigative	122510273	C23H27N5O2	405.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=NC=C3)N=C(C1)N	EC50 = 70100 nM	Poor binder
T46482	Toll-like receptor 7	B6R8SZ	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccco)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510334	C25H30N4O3	434.5	CCCN(CCCO)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B6T3BU	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=C(C=C1)F)ccn	Investigative	122510369	C26H32FN5O2	465.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)F)CCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B6TJZ1	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccc1=CC=CC=C1	Investigative	122510302	C31H35N5O2	509.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCC4=CC=CC=C4)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B74ASK	NC1=NC2=C(C=C(C1)C(=O)N(CCC)CCC)C=CC(=C2)C(=O)NC1=CC=C(C=C1)Cl	Investigative	122510362	C24H27ClN4O2	438.9	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)Cl)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B7LO8H	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)C#ccn	Investigative	122510238	C26H30N6O2	458.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)C#CCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B7NYR0	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)F	Investigative	122510313	C24H27FN4O2	422.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC=C3)F)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B7SXK8	Chembl4286476	Investigative	137515846	C20H23N5O	349.4	CCN(CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CCCC4)N)C(=O)C	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B8EV1F	Chembl4277080	Investigative	137516041	C19H17N5OS	363.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CS5)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B8MTU2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)occoccn	Investigative	122510272	C28H37N5O4	507.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC=C3)OCCOCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B8VA9Y	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccc1=CC(=CC=C1)OC	Investigative	122510255	C32H37N5O3	539.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCC4=CC(=CC=C4)OC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	B9WT0C	2-Methyl-1-(2-nonylimidazo[4,5-c]quinolin-3-yl)propan-2-ol	Investigative	56666485	C23H33N3O	367.5	CCCCCCCCCC1=NC2=C(N1CC(C)(C)O)C=NC3=CC=CC=C32	IC50 = 52940 nM	Poor binder
T46482	Toll-like receptor 7	B9YA5I	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC(=C1)C)CN	Investigative	122510269	C26H33N5O2	447.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC(=C3)CN)C)N=C(C1)N	EC50 = 61000 nM	Poor binder
T46482	Toll-like receptor 7	B9ZM4Y	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)ccn	Investigative	122510317	C26H33N5O2	447.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)CCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BA5O0B	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)CO	Investigative	122510333	C24H29N5O3	435.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CO)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BAJY26	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)CN	Investigative	122510290	C25H31N5O2	433.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BBA1H2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)CO	Investigative	122510321	C24H29N5O3	435.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)CO)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BBJS03	3-Methyl-2-nonyl-imidazo[4,5-c]quinoline	Investigative	56659558	C20H27N3	309.4	CCCCCCCCCC1=NC2=C(N1C)C=NC3=CC=CC=C32	IC50 = 68800 nM	Poor binder
T46482	Toll-like receptor 7	BC80XR	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=CC=C1	Investigative	122510230	C24H28N4O2	404.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC=C3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BCE2O7	Chembl4293700	Investigative	137515546	C21H19N5O	357.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CC=C5)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BCI3O2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)CC(C)C)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510270	C26H32N4O2	432.6	CCCN(CC(C)C)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BCSQ20	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)occn	Investigative	122510248	C25H32N6O3	464.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CN=C3)OCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BCXS43	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CN=CS1	Investigative	122510345	C21H25N5O2S	411.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CS3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BE2DK0	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510240	C25H30N4O2	418.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BF12RQ	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC(=C1)C)C	Investigative	122510297	C26H32N4O2	432.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC(=C3)C)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BF1RS2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccc1=CC=C(C=C1)CN	Investigative	122510295	C32H38N6O2	538.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCC4=CC=C(C=C4)CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BFL7S9	NC1=NC2=C(C=C(C1)C(=O)N(CCC)CCC)C=CC(=C2)C(=O)NC1=CC(=CC=C1)Cl	Investigative	122510267	C24H27ClN4O2	438.9	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC=C3)Cl)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BFZX23	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1N(C=NC=1)C	Investigative	122510259	C22H28N6O2	408.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CN3C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BG6HD9	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC=C(C=C1)CN	Investigative	122510340	C25H31N5O2	433.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BGU1L0	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)CN(C)C	Investigative	122510360	C26H34N6O2	462.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CN(C)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BH17VO	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)ccccn	Investigative	122510282	C27H36N6O2	476.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)CCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BH6VF3	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)C(=O)N1cccc1	Investigative	122510382	C29H35N5O3	501.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C(=O)N4CCCC4)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BHP47W	Chembl4207057	Investigative	145975440	C12H10ClN3O2S	295.75	CC1=NC(=CS1)C(=O)NNC(=O)C2=CC(=CC=C2)Cl	IC50 = 60000 nM	Poor binder
T46482	Toll-like receptor 7	BI2T5K	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C(=NC=CC=1)C	Investigative	122510280	C24H29N5O2	419.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=C(N=CC=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BIC5J4	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)\\C=C/CN	Investigative	122510359	C26H32N6O2	460.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)/C=C\\CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BIJ63M	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)CN	Investigative	122510365	C24H30N6O2	434.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BJ5B2W	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)CC	Investigative	122510276	C26H32N4O2	432.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BK5J4L	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)coccoccn	Investigative	122510254	C29H39N5O4	521.7	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)COCCOCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BK69FJ	Chembl4283103	Investigative	137516054	C21H18FN5O	375.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CC=C5F)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BM21LW	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)CC1=CC=C(C=C1)CN)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510237	C30H33N5O2	495.6	CCCN(CC1=CC=C(C=C1)CN)C(=O)C2=CC3=C(C=C(C=C3)C(=O)NC4=CC=CC(=C4)C)N=C(C2)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BMN71L	Chembl4279629	Investigative	137515935	C22H21N5O	371.4	CC1=CC=C(C=C1)C2=CC3=C(C=C2)C4=C(C(=N3)N)NC(=N4)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BNLH28	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)cccn	Investigative	122510350	C27H35N5O2	461.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BO0XE3	Chembl4287549	Investigative	130454445	C27H35N5O4	493.6	CC(C)(C)OC(=O)N1CCN(CC1)C2=NC(=NC3=CC(=C(C=C32)OC)OCC4=CC=CC=C4)N(C)C	IC50 = 53000 nM	Poor binder
T46482	Toll-like receptor 7	BO1E7T	4-(Aminomethyl)-N-[3-[6-(3-pyrrolidin-1-ylpropoxy)-1,3-benzoxazol-2-yl]phenyl]benzamide	Investigative	137645168	C28H30N4O3	470.6	C1CCN(C1)CCCOC2=CC3=C(C=C2)N=C(O3)C4=CC(=CC=C4)NC(=O)C5=CC=C(C=C5)CN	IC50 = 66170 nM	Poor binder
T46482	Toll-like receptor 7	BP52MF	NC1=NC2=C(C=C(C1)C(=O)N(Cccc)cccc)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510275	C27H34N4O2	446.6	CCCCN(CCCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BP81ZO	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)C(F)(F)F	Investigative	122510331	C25H27F3N4O2	472.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BPGY79	Chembl4276704	Investigative	137515571	C21H25N7O	391.5	CCC(=O)N(CC)CC1=NC2=C(N1CC)C3=C(C=C(C=C3)C4=CC=NN4)N=C2N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BQ2S8U	2-Amino-N4,N4-dipropyl-N8-(3-pyridyl)-3H-1-benzazepine-4,8-dicarboxamide	Investigative	122510241	C23H27N5O2	405.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC=C3)N=C(C1)N	EC50 = 80800 nM	Poor binder
T46482	Toll-like receptor 7	BQ87OY	N-[[3-[(4-Methoxyphenyl)methyl]imidazo[4,5-c]quinolin-2-yl]methyl]ethanamine	Investigative	56673358	C21H22N4O	346.4	CCNCC1=NC2=C(N1CC3=CC=C(C=C3)OC)C=NC4=CC=CC=C42	IC50 = 59640 nM	Poor binder
T46482	Toll-like receptor 7	BR0VI3	Chembl4280136	Investigative	137515466	C22H27N7O2	421.5	CCN(CC1=NC2=C(N1C)C3=C(C=C(C=C3)C4=CC=NN4)N=C2N)C(=O)OC(C)(C)C	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BR5NP6	NC1=NC2=C(C=C(C1)C(=O)N(CCC)CCC)C=CC(=C2)C(=O)NC1=CC(=CC(=C1)Cl)CCN	Investigative	122510315	C26H32ClN5O2	482	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CC(=C3)CCN)Cl)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BR68TQ	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)\\C=C\\CN	Investigative	122510296	C26H32N6O2	460.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)/C=C/CN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BR72YX	2-Amino-8-N-[3-(4-aminobutyl)phenyl]-4-N,4-N-dipropyl-3H-1-benzazepine-4,8-dicarboxamide	Investigative	122523748	C28H37N5O2	475.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CCCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BRTL57	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CN=NC=C1	Investigative	122510311	C22H26N6O2	406.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=NC=C3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BSFD78	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC1=CC(=CC=C1)ccn	Investigative	122510367	C26H33N5O2	447.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)CCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BT9CL3	Chembl4166427	Investigative	130289680	C24H24N4O4	432.5	CCCCC1=NC2=C(N1CC3=CC=C(C=C3)C(=O)O)C4=C(C=C(C=C4)C(=O)OC)N=C2N	EC50 = 190000 nM	Poor binder
T46482	Toll-like receptor 7	BU4JI2	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)occ	Investigative	122510301	C25H31N5O3	449.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)OCC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BUB0G6	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=NC=1	Investigative	122510305	C22H26N6O2	406.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CN=C3)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BUO86B	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)C	Investigative	122510304	C24H29N5O2	419.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BUY93J	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)C(=O)N1cccc1	Investigative	122510266	C28H34N6O3	502.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)C(=O)N4CCCC4)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BUYV49	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)ccn	Investigative	122510268	C25H32N6O2	448.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=CC(=C3)CCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BV07UL	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)cccocccn)C=CC(=C2)C(=O)NC=1C=C(C=CC=1)C	Investigative	122510357	C28H37N5O3	491.6	CCCN(CCCOCCCN)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC=CC(=C3)C)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BV4NH0	Chembl4285025	Investigative	137515380	C17H19N7	321.4	CCN(C)CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CC=NN4)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BVHQ70	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC(=CC=1)cccn	Investigative	122510298	C26H34N6O2	462.6	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CN=C(C=C3)CCCN)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BW9IJ5	NC1=NC2=C(C=C(C1)C(=O)N(Ccc)ccc)C=CC(=C2)C(=O)NC=1C=NC=C(C=1)OC	Investigative	122510250	C24H29N5O3	435.5	CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C(=O)NC3=CC(=CN=C3)OC)N=C(C1)N	EC50 ~ 100000 nM	Poor binder
T46482	Toll-like receptor 7	BZP51R	1-[2-(2-Aminoethoxy)ethyl]-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine	Investigative	10359216	C17H23N5O2	329.4	CCOCC1=NC2=C(N1CCOCCN)C3=CC=CC=C3N=C2N	EC50 ~ 100000 nM	Poor binder