TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T47094	Substance-P receptor	D0K5HI	Talnetant	Phase 2	5311424	C25H22N2O2	382.5	CC[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	D00VPT	SB222200	Preclinical	6604009	C26H24N2O	380.5	CC[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B06TUA	Methyl 6-acetamido-3-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate	Investigative	57394644	C34H33F6N5O6	721.6	CC(=O)NC1CC(=C2CCC(N2C1=O)C(=O)N[C@@H](CCC3=CNC4=CC=CC=C43)C(=O)NCC5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C(=O)OC	Ki = 79000 nM	Poor binder
T47094	Substance-P receptor	B08AVW	Methyl 3-[[(2S)-1-[benzyl(methyl)amino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-6-(phenylmethoxycarbonylamino)-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate	Investigative	57391133	C39H41N5O7	691.8	CN(CC1=CC=CC=C1)C(=O)[C@H](CCC2=CNC3=CC=CC=C32)NC(=O)C4CCC5=C(CC(C(=O)N45)NC(=O)OCC6=CC=CC=C6)C(=O)OC	Ki = 100000 nM	Poor binder
T47094	Substance-P receptor	B12QJG	N-Benzhydryl-1-[(2-methoxybenzyl)carbamoyl]-L-prolinamide	Investigative	10599370	C27H29N3O3	443.5	COC1=CC=CC=C1CNC(=O)N2CCC[C@H]2C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	B1G0HE	(2S)-N-(2-Morpholin-4-ylethyl)-2-phenyl-2-[(2-phenylacetyl)amino]acetamide	Investigative	73212591	C22H27N3O3	381.5	C1COCCN1CCNC(=O)[C@H](C2=CC=CC=C2)NC(=O)CC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B20HCD	(1R,4S,7S,9R)-4-Benzyl-5,9-bis[(2-hydroxy-5-nitrophenyl)methyl]-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349349	C34H29N5O8	635.6	C1[C@H]2C(=O)N([C@H](C(=O)N2[C@@H]3[C@]1(C4=CC=CC=C4N3)CC5=C(C=CC(=C5)[N+](=O)[O-])O)CC6=CC=CC=C6)CC7=C(C=CC(=C7)[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B21JUD	(2R)-N-[(2R)-1-[Benzyl(methyl)amino]-1-oxo-3-phenylpropan-2-yl]-1-[(2-nitrophenyl)carbamothioyl]pyrrolidine-2-carboxamide	Investigative	44337578; 74999748	C29H31N5O4S	545.7	CN(CC1=CC=CC=C1)C(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H]3CCCN3C(=S)NC4=CC=CC=C4[N+](=O)[O-]	IC50 = 100000 nM	Poor binder
T47094	Substance-P receptor	B23NOP	3-(2-Hydroxyethoxy)-2-phenyl-N-[(1R)-1-phenylpropyl]quinoline-4-carboxamide	Investigative	44266493	C27H26N2O3	426.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)OCCO	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B26CVM	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	Investigative	743974	C16H19NO3S	305.4	CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C	IC50 ~ 50118.72 nM	Poor binder
T47094	Substance-P receptor	B27SAC	3-Methyl-2-phenyl-N-[(1R)-1-phenylpropyl]quinoline-4-carboxamide	Investigative	10619783	C26H24N2O	380.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B2K5DM	(1S,4S,7S,9R)-4-Benzyl-9-hydroxy-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	11325534	C20H19N3O3	349.4	C1[C@H]2C(=O)N[C@H](C(=O)N2[C@H]3[C@@]1(C4=CC=CC=C4N3)O)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B3MLP4	(1S,4S,7S,9S)-4-Benzyl-9-[(2-methoxy-5-nitrophenyl)methyl]-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349375	C28H26N4O5	498.5	COC1=C(C=C(C=C1)[N+](=O)[O-])C[C@@]23C[C@H]4C(=O)N[C@H](C(=O)N4[C@@H]2NC5=CC=CC=C35)CC6=CC=CC=C6	IC50 = 88000 nM	Poor binder
T47094	Substance-P receptor	B3NGU0	(1S,4S,7S,9S)-4-Benzyl-9-[(2-hydroxy-5-nitrophenyl)methyl]-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349369	C27H24N4O5	484.5	C1[C@H]2C(=O)N[C@H](C(=O)N2[C@H]3[C@@]1(C4=CC=CC=C4N3)CC5=C(C=CC(=C5)[N+](=O)[O-])O)CC6=CC=CC=C6	IC50 = 98000 nM	Poor binder
T47094	Substance-P receptor	B40RPO	Cyclo(L-Pro-Gly-L-Val-Gly-O-tert-butyl-L-Tyr-Gly-L-Trp-)	Investigative	10350241	C40H52N8O8	772.9	CC(C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)OC(C)(C)C	Ki = 93000 nM	Poor binder
T47094	Substance-P receptor	B4F5BL	(2R)-N-[(2R)-1-[Benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1-[N'-(2-nitrophenyl)carbamimidoyl]pyrrolidine-2-carboxamide	Investigative	44337704; 74999804	C33H34N6O4	578.7	CN(CC1=CC=CC=C1)C(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@H]4CCCN4C(=NC5=CC=CC=C5[N+](=O)[O-])N	IC50 = 60600 nM	Poor binder
T47094	Substance-P receptor	B4SQ0G	(2S)-N-Benzhydryl-1-[N-cyano-N'-[(2-methoxyphenyl)methyl]carbamimidoyl]pyrrolidine-2-carboxamide	Investigative	10837983	C28H29N5O2	467.6	COC1=CC=CC=C1CN=C(NC#N)N2CCC[C@H]2C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	B4TL2S	(2R)-N-Benzyl-1-[2-[2-nitro-4-[2-(methylthio)ethylsulfamoyl]phenyl]hydrazinocarbonothioyl]pyrrolidine-2-carboxamide	Investigative	44375712; 75004493	C22H28N6O5S3	552.7	CSCCNS(=O)(=O)C1=CC(=C(C=C1)NNC(=S)N2CCC[C@@H]2C(=O)NCC3=CC=CC=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B5WE8S	(2R)-N-Benzhydryl-1-[[4-(2-methylsulfanylethylsulfamoyl)-2-nitroanilino]carbamothioyl]pyrrolidine-2-carboxamide	Investigative	44375286	C28H32N6O5S3	628.8	CSCCNS(=O)(=O)C1=CC(=C(C=C1)NNC(=S)N2CCC[C@@H]2C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	B67ESK	Methyl 6-acetamido-3-[[(2S)-1-[benzyl(methyl)amino]-4-(1H-indol-3-yl)-1-oxobutan-2-yl]carbamoyl]-5-oxo-2,3,6,7-tetrahydro-1H-indolizine-8-carboxylate	Investigative	57391132	C33H37N5O6	599.7	CC(=O)NC1CC(=C2CCC(N2C1=O)C(=O)N[C@@H](CCC3=CNC4=CC=CC=C43)C(=O)N(C)CC5=CC=CC=C5)C(=O)OC	Ki = 158000 nM	Poor binder
T47094	Substance-P receptor	B67YHI	6-Chloro-3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline	Investigative	24894134	C22H17Cl2FN4O	443.3	C1CN(CCC1C2=NC(=NO2)C3=C(C=C(C=C3)F)Cl)C4=CN=C5C=CC(=CC5=C4)Cl	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	B83RSH	Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester	Investigative	4529080	C25H20N2O3	396.4	COC(=O)C(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	B8V2JP	(S)-2-(Benzhydryl-carbamoyl)-pyrrolidine-1-carboxylic acid 2-methoxy-benzyl ester	Investigative	10623161	C27H28N2O4	444.5	COC1=CC=CC=C1COC(=O)N2CCC[C@H]2C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	B93ERY	Chembl4214013	Investigative	145964453	C23H16N4O5S	460.5	C1=CC=C(C=C1)S(=O)(=O)C2=C(OC(=C(C2C3=CC=C(C=C3)[N+](=O)[O-])C#N)N)C4=CC=CC=N4	IC50 = 200000 nM	Poor binder
T47094	Substance-P receptor	B94LJS	[2-Phenyl-4-((R)-1-phenyl-propylcarbamoyl)-quinolin-3-yloxy]-acetic acid	Investigative	44266599	C27H24N2O4	440.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)OCC(=O)O	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BA1BT6	3-Dimethylaminomethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide	Investigative	44266422	C28H29N3O	423.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)CN(C)C	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BA1D4J	Methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate	Investigative	6604858	C25H20N2O3	396.4	COC(=O)[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BB8UM2	(2S,3S)-2-Benzhydryl-3-benzyloxy-1-aza-bicyclo[2.2.2]octane	Investigative	10407632	C27H29NO	383.5	C1CN2CCC1[C@@H]([C@@H]2C(C3=CC=CC=C3)C4=CC=CC=C4)OCC5=CC=CC=C5	IC50 = 110000 nM	Poor binder
T47094	Substance-P receptor	BBU8K4	3-Methoxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide	Investigative	10668461	C26H24N2O2	396.5	CC[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)OC	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BC3OM0	(3R,9S,15S,21S)-9-[(4-Hydroxyphenyl)methyl]-3-(1H-indol-3-ylmethyl)-15-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone	Investigative	73353048	C36H44N8O8	716.8	CC(C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BDTY94	(2S)-N-(1,3-Diphenylpropan-2-yl)-1-[(2-methoxyphenyl)methylcarbamothioyl]pyrrolidine-2-carboxamide	Investigative	10601035	C29H33N3O2S	487.7	COC1=CC=CC=C1CNC(=S)N2CCC[C@H]2C(=O)NC(CC3=CC=CC=C3)CC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	BDW30Z	(2R,10R,12S)-3-Acetyl-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4,6,8,15,17,19-hexaene-13,21-dione	Investigative	44575660	C25H25N3O3	415.5	CC(=O)N1[C@@H]2[C@@](C[C@@H]3N2C(=O)C4=CC=CC=C4NC3=O)(C5=CC=CC=C51)C(C)(C)C=C	Ki = 170000 nM	Poor binder
T47094	Substance-P receptor	BE2B1L	N-Benzhydryl-1-[(2-aminobenzyl)thiocarbamoyl]-L-prolinamide	Investigative	10503457	C26H28N4OS	444.6	C1C[C@H](N(C1)C(=S)NCC2=CC=CC=C2N)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	BE76PQ	(2S)-N-Benzyl-1-[[4-(2-methylsulfanylethylsulfamoyl)-2-nitroanilino]carbamothioyl]pyrrolidine-2-carboxamide	Investigative	44375692	C22H28N6O5S3	552.7	CSCCNS(=O)(=O)C1=CC(=C(C=C1)NNC(=S)N2CCC[C@H]2C(=O)NCC3=CC=CC=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BF5J7A	(1R,4S,7S,9S)-4-Benzyl-9-hydroxy-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349310	C20H19N3O3	349.4	C1[C@H]2C(=O)N[C@H](C(=O)N2[C@@H]3[C@]1(C4=CC=CC=C4N3)O)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BFB93D	(1R,4S,7S,9R)-4-Benzyl-9-[(2-methoxy-5-nitrophenyl)methyl]-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349303	C28H26N4O5	498.5	COC1=C(C=C(C=C1)[N+](=O)[O-])C[C@]23C[C@H]4C(=O)N[C@H](C(=O)N4[C@H]2NC5=CC=CC=C35)CC6=CC=CC=C6	IC50 = 54000 nM	Poor binder
T47094	Substance-P receptor	BFD7J4	(3R,15S,21S)-3-(1H-Indol-3-ylmethyl)-9-[(4-methoxyphenyl)methyl]-15-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone	Investigative	73347011	C37H46N8O8	730.8	CC(C)[C@H]1C(=O)NCC(=O)NC(C(=O)NCC(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)OC	Ki = 72000 nM	Poor binder
T47094	Substance-P receptor	BFQ24U	5-{3,4,5-Tris-benzyloxy-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine	Investigative	9852911	C42H50N2O6	678.9	C1=CC=C(C=C1)CO[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCCC5=CNC6=CC=CC=C65)COCCCCCN	IC50 = 120000 nM	Poor binder
T47094	Substance-P receptor	BHD12S	Spiroquinazoline	Investigative	10409484	C23H19N5O3	413.4	C[C@]12C3=NC4=CC=CC=C4C(=O)N3[C@H](C[C@]15[C@H]6NCC(=O)N6C7=CC=CC=C57)C(=O)N2	Ki = 95000 nM	Poor binder
T47094	Substance-P receptor	BIK7Y0	2-Phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide	Investigative	1760285	C25H22N2O	366.5	CC[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BJ0YR7	N-[(R)-1-Phenylpropyl]-2-phenyl-3-hydroxyquinoline-4-carboxamide	Investigative	10691318	C25H22N2O2	382.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BJO13M	(S)-1-(2-Methoxy-benzylthiocarbamoyl)-pyrrolidine-2-carboxylic acid dibenzylamide	Investigative	10624321	C28H31N3O2S	473.6	COC1=CC=CC=C1CNC(=S)N2CCC[C@H]2C(=O)N(CC3=CC=CC=C3)CC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	BKTC92	(3R,9S,15S,21S)-3-(1H-Indol-3-ylmethyl)-9-(1H-indol-5-ylmethyl)-15-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone	Investigative	73354569	C38H45N9O7	739.8	CC(C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)CC3=CNC4=CC=CC=C43)CC5=CC6=C(C=C5)NC=C6	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BLWK13	(3R,15S,21S)-9-[Hydroxy-(4-hydroxyphenyl)methyl]-3-(1H-indol-3-ylmethyl)-15-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone	Investigative	73350088	C36H44N8O9	732.8	CC(C)[C@H]1C(=O)NCC(=O)NC(C(=O)NCC(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)CC3=CNC4=CC=CC=C43)C(C5=CC=C(C=C5)O)O	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BMD7X2	(1S,4S,7S,9S)-4-Benzyl-5,9-bis[(2-hydroxy-5-nitrophenyl)methyl]-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione	Investigative	44349376	C34H29N5O8	635.6	C1[C@H]2C(=O)N([C@H](C(=O)N2[C@H]3[C@@]1(C4=CC=CC=C4N3)CC5=C(C=CC(=C5)[N+](=O)[O-])O)CC6=CC=CC=C6)CC7=C(C=CC(=C7)[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BO8D3K	(2S)-1-[(2-Chlorophenyl)methylcarbamothioyl]-N-[(2S)-1-(N-methylanilino)-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide	Investigative	10744888	C29H31ClN4O2S	535.1	CN(C1=CC=CC=C1)C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCCN3C(=S)NCC4=CC=CC=C4Cl	IC50 = 100000 nM	Poor binder
T47094	Substance-P receptor	BP3BJ6	(2R)-N-Benzhydryl-1-[(2-nitroanilino)carbamothioyl]pyrrolidine-2-carboxamide	Investigative	44375297	C25H25N5O3S	475.6	C1C[C@@H](N(C1)C(=S)NNC2=CC=CC=C2[N+](=O)[O-])C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T47094	Substance-P receptor	BR2Y5F	Methyl (2S)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate	Investigative	6604014	C25H20N2O3	396.4	COC(=O)[C@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BSQ50Y	3-Amino-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide	Investigative	44266459	C25H23N3O	381.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)N	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BUE4N3	(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine	Investigative	14986135	C28H32N2O	412.6	COC1=CC=CC=C1CN[C@@H]2[C@H](N3CCC2CC3)C(C4=CC=CC=C4)C5=CC=CC=C5	IC50 = 81000 nM	Poor binder
T47094	Substance-P receptor	BUJQ40	3-Ethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide	Investigative	44266551	C27H26N2O	394.5	CCC1=C(C2=CC=CC=C2N=C1C3=CC=CC=C3)C(=O)N[C@H](CC)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T47094	Substance-P receptor	BX7I5B	2-Phenyl-N-[(1R)-1-phenylpropyl]quinoline-4-carboxamide	Investigative	1760287	C25H22N2O	366.5	CC[C@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	Ki ~ 100000 nM	Poor binder