TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T48040 DNA repair protein complementing XP-A cells B2ZSA9 3-[(4Z)-4-[[5-[4-[(4-Fluorophenyl)methylcarbamoyl]phenyl]furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid Investigative 132169645 C30H22FN3O5 523.5 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC=C(C=C3)C(=O)NCC4=CC=C(C=C4)F)C5=CC=CC(=C5)C(=O)O IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells B8KEA6 3-((4Z)-4-{[5-(3-Carboxyphenyl)-2-furyl]methylene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid Investigative 24893997 C23H16N2O6 416.4 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC(=CC=C3)C(=O)O)C4=CC=CC(=C4)C(=O)O IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells B9HDN1 2-(5-{(Z)-[1-(3-Carboxyphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}-2-furyl)benzoic acid Investigative 30135276 C23H16N2O6 416.4 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC=CC=C3C(=O)O)C4=CC=CC(=C4)C(=O)O IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells BA28JP 3-((4Z)-4-{[5-(4-Carboxyphenyl)-2-furyl]methylene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid Investigative 24893998 C23H16N2O6 416.4 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC=C(C=C3)C(=O)O)C4=CC=CC(=C4)C(=O)O IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells BH38EZ Schembl20840316 Investigative 5346781 C23H15ClN2O6 450.8 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC(=C(C=C3)Cl)C(=O)O)C4=CC=CC(=C4)C(=O)O IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells BJ16EZ 2-Chloro-N-(cyclopropylmethyl)-5-[5-[(Z)-[1-[3-(cyclopropylmethylcarbamoyl)phenyl]-3-methyl-5-oxopyrazol-4-ylidene]methyl]furan-2-yl]benzamide Investigative 132169746 C31H29ClN4O4 557 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC(=C(C=C3)Cl)C(=O)NCC4CC4)C5=CC=CC(=C5)C(=O)NCC6CC6 IC50 ~ 50000 nM Poor binder T48040 DNA repair protein complementing XP-A cells BU5IZ0 3-[(4Z)-4-[[5-[4-(Cyclopropylmethylcarbamoyl)phenyl]furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid Investigative 132169827 C27H23N3O5 469.5 CC\\1=NN(C(=O)/C1=C\\C2=CC=C(O2)C3=CC=C(C=C3)C(=O)NCC4CC4)C5=CC=CC(=C5)C(=O)O IC50 ~ 50000 nM Poor binder