TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48069	Insulin-like growth factor I receptor	D01PZD	Romiplostim	Approved	5329098	C15H14N2O	238.28	CC1=CC(=C(N1)/C=C\\2/C3=CC=CC=C3NC2=O)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D0E6XR	Dasatinib	Approved	3062316	C22H26ClN7O2S	488	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B0IQ9N	3-[(Z)-(4-Bromo-2-thienyl)methylidene]-1H-indol-2-one	Investigative	6036100	C13H8BrNOS	306.18	C1=CC=C2C(=C1)/C(=C/C3=CC(=CS3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B0SHG1	(Z)-1-Methyl-3-(4-dimethylaminobenzylidene)indoline-2-one	Investigative	5293755	C18H18N2O	278.3	CN1C2=CC=CC=C2/C(=C/C3=CC=C(C=C3)N(C)C)/C1=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B1A4EI	(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-one	Investigative	9547398	C27H42O3	414.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3C[C@@H]([C@@H]([C@]3(CCC2=O)C)[C@H](C)CCCC(C)C)O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B1BD8S	2-Fluoro-N'-[2-(1H-indol-3-yl)-2-oxoacetyl]benzohydrazide	Investigative	53328318	C17H12FN3O3	325.29	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NNC(=O)C3=CC=CC=C3F	IC50 = 91000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B1IH8M	N'-Phenyl-2-(1H-indole-3-yl)-2-oxoacetohydrazide	Investigative	2716301	C16H13N3O2	279.29	C1=CC=C(C=C1)NNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B1IR3H	4-[4-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenyl]-piperazine-1-carbaldehyde	Investigative	44321734	C20H18BrN3O2	412.3	C1CN(CCN1C=O)C2=CC=C(C=C2)/C=C\\3/C4=C(C=CC(=C4)Br)NC3=O	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B3B8SM	5-[2-(2,4-Dichloro-benzyloxy)-benzylidene]-thiazolidine-2,4-dione	Investigative	1232669	C17H11Cl2NO3S	380.2	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=O)S2)OCC3=C(C=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B3QYM6	3-(3-Tert-Butyl-4-methoxy-benzylidene)-5-chloro-1,3-dihydro-indol-2-one	Investigative	10783444	C20H20ClNO2	341.8	CC(C)(C)C1=C(C=CC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B45EMH	2-(3,4-Dihydroxybenzylidene)benzofuran-3(2H)-one	Investigative	21100709	C15H10O4	254.24	C1=CC=C2C(=C1)C(=O)/C(=C\\C3=CC(=C(C=C3)O)O)/O2	IC50 = 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B49VLE	3-(4-(Dimethylamino)benzylidene)-1,3-dihydro-2H-indol-2-one	Investigative	6450842	C17H16N2O	264.32	CN(C)C1=CC=C(C=C1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B4RF3H	(Z)-3-(4-Hydroxyphenyl)-2-pyridin-2-ylprop-2-enenitrile	Investigative	135410197	C14H10N2O	222.24	C1=CC=NC(=C1)/C(=C/C2=CC=C(C=C2)O)/C#N	IC50 = 72800 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B4U7AY	3-[1-(3-Tert-Butyl-4-methoxy-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	9995374	C20H21NO2	307.4	CC(C)(C)C1=C(C=CC(=C1)/C=C\\2/C3=CC=CC=C3NC2=O)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B57BWQ	4-(2-Methoxyethyl)phenol	Investigative	92516	C9H12O2	152.19	COCCC1=CC=C(C=C1)O	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B60CAW	(R)-3-(6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide	Investigative	46232555	C20H15Cl2FN2O2	405.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)/C=C/C(=O)N	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B6C9FG	(3Z)-3-[(4-Bromophenyl)methylidene]-1H-indol-2-one	Investigative	964113	C15H10BrNO	300.15	C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B6JQ1V	3-[1-(4-Piperidin-1-yl-phenyl)-ethylidene]-1,3-dihydro-indol-2-one	Investigative	10663368	C21H22N2O	318.4	C/C(=C\\1/C2=CC=CC=C2NC1=O)/C3=CC=C(C=C3)N4CCCCC4	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B6LXB4	N-[2-(3-Chlorophenyl)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide	Investigative	53330630	C18H15ClN2O2	326.8	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCCC3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B6LZ5N	3-(4-Dimethylamino-benzylidene)-4-methyl-1,3-dihydro-indol-2-one	Investigative	10755069	C18H18N2O	278.3	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(C=C3)N(C)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B6SP0Y	N'-(4-Chlorophenyl)-2-(1H-indole-3-yl)-2-oxoacetohydrazide	Investigative	10805173	C16H12ClN3O2	313.74	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NNC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B74OWN	3-[1-(4-Piperidin-1-yl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	9948410	C20H20N2O	304.4	C1CCN(CC1)C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B78RHA	(3Z)-3-[4-(Morpholin-4-yl)benzylidene]-1,3-dihydro-2H-indol-2-one	Investigative	2379240	C19H18N2O2	306.4	C1COCCN1C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B7TOG3	5-Nitro-3-(1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10658651	C13H9N3O3	255.23	C1=CNC(=C1)/C=C\\2/C3=C(C=CC(=C3)[N+](=O)[O-])NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8G6DZ	AZ-Dyrk1B-33	Investigative	118735338	C19H16N4	300.4	CC1=NC=CC(=N1)C2=CN(C3=C2C=CN=C3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8LJS5	3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	2358462	C14H11NO2	225.24	CC1=CC=C(O1)/C=C/2\\C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8N9VS	(3Z)-4-Methyl-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one	Investigative	10489322	C14H12N2O	224.26	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=CN3	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8RV9Z	CID 60154336	Investigative	60154336	C15H16BrN7	374.24	CC1=C(N=CC=C1)CNC2=NC=C(C(=N2)NC3=NNC(=C3)C)Br	IC50 = 50118.72 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8USO3	3-[(Z)-(3-Bromo-2-thienyl)methylidene]-1H-indol-2-one	Investigative	5707304	C13H8BrNOS	306.18	C1=CC=C2C(=C1)/C(=C/C3=C(C=CS3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B8YTQ3	CID 49806721	Investigative	49806721	C28H30N4O2	454.6	CCC1=CC2=C(C=C1N3CCN(CC3)C4COC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B97RPS	Serotonin hydrochloride	Investigative	160436	C10H13ClN2O	212.67	C1=CC2=C(C=C1O)C(=CN2)CCN.Cl	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B9E1VS	5-Chloro-3-(4-hydroxy-3,5-diisopropyl-benzylidene)-1,3-dihydro-indol-2-one	Investigative	44321317	C21H22ClNO2	355.9	CC(C)C1=CC(=CC(=C1O)C(C)C)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B9GWJ2	N'-[2-(1H-Indol-3-yl)-2-oxoacetyl]benzohydrazide	Investigative	2716309	C17H13N3O3	307.3	C1=CC=C(C=C1)C(=O)NNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B9PAC6	(E)-5-(3-Fluoro-4-(pyrrolidin-1-yl)benzylidene)thiazolidine-2,4-dione	Investigative	1210312	C14H13FN2O2S	292.33	C1CCN(C1)C2=C(C=C(C=C2)/C=C/3\\C(=O)NC(=O)S3)F	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	B9ZHM4	5-(4-Benzyloxy-3-methoxy-benzylidene)-thiazolidine-2,4-dione	Investigative	1922265	C18H15NO4S	341.4	COC1=C(C=CC(=C1)/C=C/2\\C(=O)NC(=O)S2)OCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BA9JN1	(5Z)-5-(3-Bromo-5-ethoxy-4-propoxybenzylidene)-1,3-thiazolidine-2,4-dione	Investigative	1810702	C15H16BrNO4S	386.3	CCCOC1=C(C=C(C=C1Br)/C=C\\2/C(=O)NC(=O)S2)OCC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BACL08	N-[2-(4-Chlorophenyl)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide	Investigative	2226536	C18H15ClN2O2	326.8	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BACY73	(3Z)-3-(4-Hydroxybenzylidene)-1,3-dihydro-2H-indol-2-one	Investigative	5874584	C15H11NO2	237.25	C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)O)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BB0Q7T	N'-(4-Bromophenyl)-2-(1H-indol-3-yl)-2-oxoacetohydrazide	Investigative	53330628	C16H12BrN3O2	358.19	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NNC3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BBE6T2	2-(1H-Indol-3-yl)-N'-(4-iodophenyl)-2-oxoacetohydrazide	Investigative	53330629	C16H12IN3O2	405.19	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NNC3=CC=C(C=C3)I	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BC87JM	(Z)-4-Methyl-3-(4-morpholinobenzylidene)indolin-2-one	Investigative	10663503	C20H20N2O2	320.4	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(C=C3)N4CCOCC4	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BC9U7X	(3Z)-3-[(4-Methoxyphenyl)methylidene]-1H-indol-2-one	Investigative	727518	C16H13NO2	251.28	COC1=CC=C(C=C1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BCK69E	CID 42602949	Investigative	42602949	C23H25N7O2	431.5	COC1=CC(=CC(=C1)CCC2=CC(=NN2)NC3=NC(=NC=C3)NCC4=CC=CC=N4)OC	IC50 = 79432.82 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BD01AP	4-Methyl-3-(5-methylsulfanyl-thiophen-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10779668	C15H13NOS2	287.4	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(S3)SC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BD05ME	(Z)-4-(4-((4-Methyl-2-oxoindolin-3-ylidene)methyl)phenyl)piperazine-1-carbaldehyde	Investigative	10593765	C21H21N3O2	347.4	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(C=C3)N4CCN(CC4)C=O	IC50 = 67600 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BD17KR	(3Z)-3-[(4-Chloro-1-methylpyrazol-3-yl)methylidene]-1H-indol-2-one	Investigative	136026516	C13H10ClN3O	259.69	CN1C=C(C(=N1)/C=C\\2/C3=CC=CC=C3NC2=O)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BD9KT1	1-[4-[3-Methoxy-4-[[6-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-4-yl]amino]phenyl]piperazin-1-yl]ethanone	Investigative	118735325	C25H27N7O2	457.5	CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=NC(=C3)C4=CN(C5=C4C=CN=C5)C)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BDB2U4	3-[1-(5-Ethyl-thiophen-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	10682457	C15H13NOS	255.3	CCC1=CC=C(S1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BDK9R0	Calicoferol C	Investigative	10024683	C28H44O2	412.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CC[C@H]2O)C)[C@H](C)CCC(=C)C(C)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BDTC35	N-(3-Isoquinolin-4-yl-phenyl)-2-[(pyridin-4-ylmethyl)-amino]-benzamide	Investigative	44368815	C28H22N4O	430.5	C1=CC=C2C(=C1)C=NC=C2C3=CC(=CC=C3)NC(=O)C4=CC=CC=C4NCC5=CC=NC=C5	IC50 = 64000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BE1XL7	N-(4-Chlorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide	Investigative	5304328	C17H13ClN2O2	312.7	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BF2YG3	N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(1H-indol-3-yl)-2-oxoacetamide	Investigative	342168	C20H20N2O4	352.4	COC1=C(C=C(C=C1)CCNC(=O)C(=O)C2=CNC3=CC=CC=C32)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BF32AR	Calicoferol B	Investigative	10047545	C27H44O3	416.6	CC1=C(C=C(C=C1)O)CC[C@@H]2[C@@H](CC[C@]3([C@H]2C[C@@H]([C@@H]3[C@H](C)CCCC(C)C)O)C)O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BFK2W1	(3E)-3-(Furan-2-ylmethylidene)-1H-indol-2-one	Investigative	5713379	C13H9NO2	211.22	C1=CC=C2C(=C1)/C(=C\\C3=CC=CO3)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BFQR96	3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-4-methyl-1,3-dihydro-indol-2-one	Investigative	10264222	C16H16N2O	252.31	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=C(C=C(N3)C)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BFZN15	(5E)-5-{4-[(2-Chlorobenzyl)oxy]benzylidene}-1,3-thiazolidine-2,4-dione	Investigative	1227456	C17H12ClNO3S	345.8	C1=CC=C(C(=C1)COC2=CC=C(C=C2)/C=C/3\\C(=O)NC(=O)S3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BG0N6H	N'-[1H-Indol-3-yl(oxo)acetyl]-4-nitrobenzohydrazide	Investigative	4269048	C17H12N4O5	352.3	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NNC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BGE9L7	2,3-[Ethyliminobis[ethyleneoxyethylene(1H-indole-1,3-diyl)]]maleimide	Investigative	10207821	C30H32N4O4	512.6	CCN1CCOCCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCOCC1)C6=CC=CC=C65)C(=O)NC4=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BGQE67	N'-[2-(1H-Indol-3-yl)-2-oxoacetyl]-4-methylbenzohydrazide	Investigative	53328118	C18H15N3O3	321.3	CC1=CC=C(C=C1)C(=O)NNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 = 82000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BI4JU2	6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	10728035	C13H9FN2O	228.22	C1=CNC(=C1)/C=C\\2/C3=C(C=C(C=C3)F)NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BKQ9H7	N-(2-{2-Dimethylaminoethyl-methylamino}-4-methoxy-5-{[5-methyl-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide	Investigative	86677253	C29H35N7O2	513.6	CC1=CN=C(N=C1C2=CN(C3=CC=CC=C32)C)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC	IC50 = 196000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BKZ0M7	3-(5-(1H-Imidazol-1-yl)-7-methyl-1H-benzo[d]imidazol-2-yl)-4-(2-(2-chlorophenyl)-2-hydroxyethylamino)pyridin-2(1H)-one	Investigative	135553383	C24H21ClN6O2	460.9	CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC=CC=C4Cl)O)N5C=CN=C5	IC50 = 180000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BL3J7V	3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-5-methyl-1,3-dihydro-indol-2-one	Investigative	10562777	C16H16N2O	252.31	CC1=CC\\2=C(C=C1)NC(=O)/C2=C\\C3=C(C=C(N3)C)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BLB38M	3-[1-(4-Bromo-phenyl)-meth-(Z)-ylidene]-1-methyl-1,3-dihydro-indol-2-one	Investigative	5427224	C16H12BrNO	314.18	CN1C2=CC=CC=C2/C(=C/C3=CC=C(C=C3)Br)/C1=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BM59RL	3-[1-(4-Chloro-1H-pyrazol-3-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	135536640	C12H8ClN3O	245.66	C1=CC=C2C(=C1)/C(=C/C3=C(C=NN3)Cl)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BM9V6U	N-Cyclopentyl-4-[4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-yl]benzamide	Investigative	118735332	C23H21N5O	383.4	C1CCC(C1)NC(=O)C2=CC=C(C=C2)C3=NC=CC(=N3)C4=CNC5=C4C=CN=C5	IC50 = 67727 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BMBP07	4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-benzoic acid	Investigative	2365265	C16H11NO3	265.26	C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)C(=O)O)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BN3Y0E	3-[[5-Cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino]-4-methyl-N-(1,2-oxazol-3-yl)benzamide	Investigative	11235063	C21H21N7O2	403.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C(C(=NC=N3)NC4CCCC4)C#N	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BN47UZ	3-[1-(3,4-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	10236164	C15H14N2O	238.28	CC1=CNC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BN7CE8	(Z)-5-(2-Bromo-5-ethoxy-4-methoxybenzylidene)thiazolidine-2,4-dione	Investigative	46229187	C13H12BrNO4S	358.21	CCOC1=C(C=C(C(=C1)/C=C\\2/C(=O)NC(=O)S2)Br)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BNIV50	(Z)-5-(4-Butoxybenzylidene)thiazolidine-2,4-dione	Investigative	1810679	C14H15NO3S	277.34	CCCCOC1=CC=C(C=C1)/C=C\\2/C(=O)NC(=O)S2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BO03RH	CID 60154345	Investigative	60154345	C16H20N8O3	372.38	COCCCC1=CC(=NN1)NC2=NC(=NC=C2)NCC3=CC(=NO3)C(=O)N	IC50 = 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BO5R7P	3-(5-Ethyl-furan-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10537949	C15H13NO2	239.27	CCC1=CC=C(O1)/C=C/2\\C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BPLJ98	(3Z)-3-[[4-(Dimethylamino)phenyl]methylidene]-6-fluoro-1H-indol-2-one	Investigative	44321717	C17H15FN2O	282.31	CN(C)C1=CC=C(C=C1)/C=C\\2/C3=C(C=C(C=C3)F)NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BPV0N8	N'-[2-(1H-Indol-3-yl)-2-oxoacetyl]-4-methoxybenzohydrazide	Investigative	53328119	C18H15N3O4	337.3	COC1=CC=C(C=C1)C(=O)NNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 = 54000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BQ4YP0	Methyl 3-[4-methyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoate	Investigative	10215023	C18H18N2O3	310.3	CC1=C(NC=C1CCC(=O)OC)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BQW0B2	(3Z)-3-[(5-Methylsulfanylthiophen-2-yl)methylidene]-1H-indol-2-one	Investigative	10636005	C14H11NOS2	273.4	CSC1=CC=C(S1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BQW81G	(3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylidene]-6-fluoro-1H-indol-2-one	Investigative	10753550	C15H13FN2O	256.269	CC1=CC(=C(N1)/C=C\\2/C3=C(C=C(C=C3)F)NC2=O)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BRL56D	5-Amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl)-1H-pyrazole-4-carboxamide	Investigative	49838879	C21H17FN6O3	420.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC(=O)C3=C(N(N=C3)C4=CC=CC=C4F)N	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BS5IC7	2-(1H-Indol-3-yl)-N-(4-methylbenzyl)-2-oxoacetamide	Investigative	7117329	C18H16N2O2	292.3	CC1=CC=C(C=C1)CNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 = 63000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BSC9A5	5-Chloro-3-(1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10562306	C13H9ClN2O	244.67	C1=CNC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BSG8O3	N-(3-Chloro-benzyl)-2-(1H-indol-3-yl)-2-oxo-acetamide	Investigative	10686611	C17H13ClN2O2	312.7	C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCC3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BTQK89	3-[1-(4-Pyrrolidin-1-yl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	5427216	C19H18N2O	290.4	C1CCN(C1)C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BU3CK2	Tert-Butyl-2-{5-(4-hydroxyphenethoxy)-1-{5-[4-(methylthio)phenyl]pentyl}-1H-indole-3-yl}ethyl carbamate	Investigative	46888666	C35H44N2O4S	588.8	CC(C)(C)OC(=O)NCCC1=CN(C2=C1C=C(C=C2)OCCC3=CC=C(C=C3)O)CCCCCC4=CC=C(C=C4)SC	IC50 ~ 50000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BU5E9W	(3Z)-3-[(1-Methylpyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	6536705	C14H12N2O	224.26	CN1C=CC=C1/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BU6O8Q	2-(1H-Indol-3-yl)-N-[2-(4-methylphenyl)ethyl]-2-oxoacetamide	Investigative	12758175	C19H18N2O2	306.4	CC1=CC=C(C=C1)CCNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 = 52000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BU9ME0	N-[4-(4-Methylpiperazin-1-yl)phenyl]-6-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-4-amine	Investigative	118735322	C22H23N7	385.5	CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=NC(=C3)C4=CNC5=C4C=CN=C5	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BUX9D5	(Z)-5-(4-(2,4-Dichlorobenzyloxy)-3-methoxybenzylidene)thiazolidine-2,4-dione	Investigative	1214096	C18H13Cl2NO4S	410.3	COC1=C(C=CC(=C1)/C=C\\2/C(=O)NC(=O)S2)OCC3=C(C=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BV95PD	(3Z)-3-[(3-Ethyl-4,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	10635478	C17H18N2O	266.34	CCC1=C(NC(=C1C)C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BW8S6G	3-[2-(4-Methylsulfonylphenyl)pyrimidin-4-yl]-1H-pyrrolo[2,3-c]pyridine	Investigative	118735333	C18H14N4O2S	350.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC=CC(=N2)C3=CNC4=C3C=CN=C4	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BWET45	3-(2-Methylpyrimidin-4-yl)-1H-pyrrolo[2,3-c]pyridine	Investigative	118735337	C12H10N4	210.23	CC1=NC=CC(=N1)C2=CNC3=C2C=CN=C3	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BWI8R7	(5Z)-5-[3,4-Dimethoxy-5-(prop-2-en-1-yl)benzylidene]-1,3-thiazolidine-2,4-dione	Investigative	1232267	C15H15NO4S	305.4	COC1=CC(=CC(=C1OC)CC=C)/C=C\\2/C(=O)NC(=O)S2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BWUP40	(Z)-5-(4-Ethoxy-3-isobutoxybenzylidene)thiazolidine-2,4-dione	Investigative	46229173	C16H19NO4S	321.4	CCOC1=C(C=C(C=C1)/C=C\\2/C(=O)NC(=O)S2)OCC(C)C	IC50 = 63900 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BXT54C	(3Z)-3-[(4-Ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	10587839	C17H18N2O	266.34	CCC1=C(NC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BY04XF	3-(3-Bromo-5-tert-butyl-4-methoxy-benzylidene)-5-chloro-1,3-dihydro-indol-2-one	Investigative	44321395	C20H19BrClNO2	420.7	CC(C)(C)C1=C(C(=CC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O)Br)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BY7MP5	5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723185	C21H19N3O4	377.4	COC1=CC(=CC(=C1OC)OC)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BZ2O8P	(3Z)-3-[(3-Bromo-5-tert-butyl-4-methoxyphenyl)methylidene]-1H-indol-2-one	Investigative	44321301	C20H20BrNO2	386.3	CC(C)(C)C1=C(C(=CC(=C1)/C=C\\2/C3=CC=CC=C3NC2=O)Br)OC	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	BZ8WM4	4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrole-3-carboxylic acid ethyl ester	Investigative	10613858	C17H16N2O3	296.32	CCOC(=O)C1=CNC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D00ATA	(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one	Investigative	5908088	C13H10N2O	210.23	C1=CC=C2C(=C1)/C(=C/C3=CC=CN3)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D07OSK	VEGF receptor 2 kinase inhibitor I	Investigative	6419834	C18H18N2O3	310.3	CCOC(=O)C1=C(NC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O)C	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D08HGK	N-Benzyl-2-(1H-indol-3-yl)-2-oxo-acetamide	Investigative	3149447	C17H14N2O2	278.3	C1=CC=C(C=C1)CNC(=O)C(=O)C2=CNC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D0A4XJ	SU5402	Investigative	5289418	C17H16N2O3	296.32	CC1=CNC(=C1CCC(=O)O)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T48069	Insulin-like growth factor I receptor	D0HE0E	SU4984	Investigative	5941540	C20H19N3O2	333.4	C1CN(CCN1C=O)C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder