TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48703	Toll-like receptor 8	B0P7ZI	Chembl4284645	Investigative	137515383	C21H21N5OS	391.5	CCN1C(=NC2=C1C3=C(C=C(C=C3)C4=CC=CS4)N=C2N)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	B1CV4Q	Chembl4288029	Investigative	137516341	C24H21N7O	423.5	C1[C@H](CN(C1=O)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)N5C=CC=N5)N)C6=CC=CC=C6	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	B35QVN	Chembl4278564	Investigative	137515794	C21H21N5O	359.4	CCN(CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CC=CC=C4)N)C(=O)C	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	B4X1ZB	Chembl4290288	Investigative	137515213	C22H21N5O	371.4	CC1=CC(=CC=C1)C2=CC3=C(C=C2)C4=C(C(=N3)N)NC(=N4)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	B5JBP6	6-Amino-2-butoxy-9-(5-piperidin-4-ylpentyl)-7H-purin-8-one;hydrochloride	Investigative	118727491	C19H33ClN6O2	413	CCCCOC1=NC(=C2C(=N1)N(C(=O)N2)CCCCCC3CCNCC3)N.Cl	EC50 = 57000 nM	Poor binder
T48703	Toll-like receptor 8	B7SXK8	Chembl4286476	Investigative	137515846	C20H23N5O	349.4	CCN(CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CCCC4)N)C(=O)C	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	B8EV1F	Chembl4277080	Investigative	137516041	C19H17N5OS	363.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CS5)N	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BCE2O7	Chembl4293700	Investigative	137515546	C21H19N5O	357.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CC=C5)N	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BK69FJ	Chembl4283103	Investigative	137516054	C21H18FN5O	375.4	C1CC(=O)N(C1)CC2=NC3=C(N2)C(=NC4=C3C=CC(=C4)C5=CC=CC=C5F)N	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BMN71L	Chembl4279629	Investigative	137515935	C22H21N5O	371.4	CC1=CC=C(C=C1)C2=CC3=C(C=C2)C4=C(C(=N3)N)NC(=N4)CN5CCCC5=O	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BPGY79	Chembl4276704	Investigative	137515571	C21H25N7O	391.5	CCC(=O)N(CC)CC1=NC2=C(N1CC)C3=C(C=C(C=C3)C4=CC=NN4)N=C2N	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BR0VI3	Chembl4280136	Investigative	137515466	C22H27N7O2	421.5	CCN(CC1=NC2=C(N1C)C3=C(C=C(C=C3)C4=CC=NN4)N=C2N)C(=O)OC(C)(C)C	EC50 ~ 100000 nM	Poor binder
T48703	Toll-like receptor 8	BRI1N5	6-Amino-2-butoxy-9-(4-piperidin-4-ylbutyl)-7H-purin-8-one;hydrochloride	Investigative	118727490	C18H31ClN6O2	398.9	CCCCOC1=NC(=C2C(=N1)N(C(=O)N2)CCCCC3CCNCC3)N.Cl	EC50 = 131000 nM	Poor binder
T48703	Toll-like receptor 8	BV4NH0	Chembl4285025	Investigative	137515380	C17H19N7	321.4	CCN(C)CC1=NC2=C(N1)C(=NC3=C2C=CC(=C3)C4=CC=NN4)N	EC50 ~ 100000 nM	Poor binder