TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T51191	Histone deacetylase 2	D0Y3KG	Valproate	Approved	3121	C8H16O2	144.21	CCCC(CCC)C(=O)O	IC50 = 62000 nM	Poor binder
T51191	Histone deacetylase 2	D0B7CH	Phenylbutyrate	Phase 2	4775	C10H12O2	164.2	C1=CC=C(C=C1)CCCC(=O)O	IC50 = 65000 nM	Poor binder
T51191	Histone deacetylase 2	D0L1NO	PMID29671355-Compound-47a	Patented	72722126	C20H15F2N3O2	367.3	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@]2(C(=O)NO)F)C3=CC=C(C=C3)C4=NC=C(C=N4)F	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	B03PZD	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide	Investigative	136025984	C19H25N3O2S	359.5	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B07EKA	Chembl4283418	Investigative	134283796	C21H26N2O3	354.4	C1=CC=C(C=C1)C[C@@H](CCCC(=O)NC2=CC=CC=C2)CCC(=O)NO	IC50 = 51000 nM	Poor binder
T51191	Histone deacetylase 2	B0E3XF	N-Hydroxy-2-pentyl-N'-phenyloctanediamide	Investigative	134143927	C19H30N2O3	334.5	CCCCCC(CCCCCC(=O)NC1=CC=CC=C1)C(=O)NO	IC50 = 58000 nM	Poor binder
T51191	Histone deacetylase 2	B0HXB5	N-(2-Amino-5-azidophenyl)-4-(3-azidopropanoylamino)benzamide	Investigative	62706169	C16H15N9O2	365.35	C1=CC(=CC=C1C(=O)NC2=C(C=CC(=C2)N=[N+]=[N-])N)NC(=O)CCN=[N+]=[N-]	IC50 = 77000 nM	Poor binder
T51191	Histone deacetylase 2	B0OYP1	(1R,2R,3R)-N-Hydroxy-2-(1-methylpyrazol-4-yl)-3-phenylcyclopropane-1-carboxamide	Investigative	60148646	C14H15N3O2	257.29	CN1C=C(C=N1)[C@@H]2[C@H]([C@H]2C(=O)NO)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	B0R4TM	2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one	Investigative	135497781	C17H20N2O2S	316.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B1HBJ8	N-(4-Amino-3''-nitrobiphenyl-3-yl)benzamide	Investigative	46887435	C19H15N3O3	333.3	C1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC(=CC=C3)[N+](=O)[O-])N	IC50 = 200000 nM	Poor binder
T51191	Histone deacetylase 2	B1J8GQ	3-(Benzylamino)propionohydroxamic acid monohydrochloride	Investigative	211808	C10H14N2O2	194.23	C1=CC=C(C=C1)CNCCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B1SXO5	N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56659403	C15H15N3O2S	301.4	CC1=NC(=NC=C1)SCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B24FWP	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(sulfamoylamino)propyl]benzamide	Investigative	134153768	C23H22F4N6O4S2	586.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCNS(=O)(=O)N)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B2CQD1	Chembl4218901	Investigative	145970091	C18H21N3O5S	391.4	CC(C)[C@@H](C(=O)NC1=CC=CC=C1)NS(=O)(=O)C2=CC=CC(=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B2HF4T	Chembl4214401	Investigative	145973656	C24H22N4O5S	478.5	C1=CC=C(C=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NS(=O)(=O)C4=CC=CC(=C4)C(=O)NO	IC50 = 70400 nM	Poor binder
T51191	Histone deacetylase 2	B2VLJ6	N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide	Investigative	136025842	C14H15N3O2S	289.35	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B3WQR6	Chembl4214404	Investigative	145973876	C19H19F3N2O2	364.4	C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B47AQS	7-[3-[[(5S,5As,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenoxy]-N-(2-aminophenyl)heptanamide	Investigative	72696206	C40H43N3O9	709.8	COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)NC6=CC(=CC=C6)OCCCCCCC(=O)NC7=CC=CC=C7N	IC50 = 53520 nM	Poor binder
T51191	Histone deacetylase 2	B4JO8K	(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-carbonylamino)heptylboronic acid	Investigative	42637373	C23H26BN3O4S	451.4	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CN=CS3)(O)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B4NL8Q	N-Hydroxy-3-[1-(2-phenylethyl)triazol-4-yl]benzamide	Investigative	136030780	C17H16N4O2	308.33	C1=CC=C(C=C1)CCN2C=C(N=N2)C3=CC(=CC=C3)C(=O)NO	IC50 = 76000 nM	Poor binder
T51191	Histone deacetylase 2	B4PR2D	Chembl4210091	Investigative	145966861	C21H19N3O5S	425.5	C1=CC=C(C=C1)[C@@H](C(=O)NC2=CC=CC=C2)NS(=O)(=O)C3=CC=CC(=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B4YZ2S	6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide	Investigative	44359800	C14H20N2O3	264.32	CC(=O)N(CCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B5H4IM	(R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)heptanamide	Investigative	25207860	C31H46N2O3	494.7	C[C@H](CCCCC(=O)NC1=CC=CC=C1N)[C@H]2CC[C@@H]\\3[C@@]2(CCC/C3=C\\C=C4C[C@H](C[C@@H](C4)O)O)C	IC50 = 189000 nM	Poor binder
T51191	Histone deacetylase 2	B5HIZ3	N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	56673261	C16H16N2O4	300.31	CC1=CC(=O)NC(=C1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B61DOE	Chembl4206571	Investigative	145975913	C19H22N2O3	326.4	COC1=CC=CC(=C1)C2C3=CC=CC=C3CCN2CCC(=O)NO	IC50 = 69000 nM	Poor binder
T51191	Histone deacetylase 2	B6GT3E	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(sulfamoylamino)hexyl]benzamide	Investigative	134135812	C26H28F4N6O4S2	628.7	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCCCCNS(=O)(=O)N)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B6I1JR	Schembl21996151	Investigative	134141877	C31H23F4N5O3S	621.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)CN3C=CC4=C3C=CC(=C4)/C=C/C(=O)NO)F)C5=CC(=C(C=C5)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B6SGQ3	Chembl4213891	Investigative	145966543	C19H19F3N2O2	364.4	C1CN(C(C2=CC=CC=C21)C3=CC(=CC=C3)C(F)(F)F)CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B76NHE	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide	Investigative	136086923	C17H21N3O2S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B7JEZ8	1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one	Investigative	135462117	C8H10N2O2S	198.24	CC1=CC(=O)NC(=N1)SCC(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B7MV0J	(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acid	Investigative	86294747	C14H12N2O4S	304.32	C1=CC=C(C=C1)[C@H](C(=O)O)NC(=O)C2=CC=CC(=S)N2O	IC50 = 95000 nM	Poor binder
T51191	Histone deacetylase 2	B81YTQ	N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide	Investigative	56666337	C16H15NO3S	301.4	CC(=O)NC1=CC=C(C=C1)C(=O)CSC2=CC=CC(=C2)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B85BKY	2-Benzyl-N-hydroxy-N'-phenyloctanediamide	Investigative	44431499	C21H26N2O3	354.4	C1=CC=C(C=C1)CC(CCCCCC(=O)NC2=CC=CC=C2)C(=O)NO	IC50 = 110000 nM	Poor binder
T51191	Histone deacetylase 2	B86FDG	3-(1-Benzyltriazol-4-yl)-N-hydroxybenzamide	Investigative	136030779	C16H14N4O2	294.31	C1=CC=C(C=C1)CN2C=C(N=N2)C3=CC(=CC=C3)C(=O)NO	IC50 = 65000 nM	Poor binder
T51191	Histone deacetylase 2	B93MKY	N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide	Investigative	136025843	C15H17N3O3S	319.4	CC1=CC(=O)NC(=N1)SCC(C2=CC=C(C=C2)NC(=O)C)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B9B8NI	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(3-hydroxy-2-oxopyridin-1-yl)propyl]benzamide	Investigative	134157355	C28H23F4N5O4S	601.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCN3C=CC=C(C3=O)O)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	B9IN4F	Chembl4204967	Investigative	145977336	C12H16N2O2	220.27	C1CN(CC2=CC=CC=C21)CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BABT97	2-Azidoethyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate	Investigative	71449818	C24H29N7O5	495.5	COC1=CC(=CC(=C1)N=[N+]=[N-])COC2=CC=C(C=C2)NC(=O)CCCCCCC(=O)OCCN=[N+]=[N-]	IC50 = 72000 nM	Poor binder
T51191	Histone deacetylase 2	BBQ7H4	Chembl4218825	Investigative	145970309	C20H24N2O3	340.4	CCOC1=CC=C(C=C1)C2C3=CC=CC=C3CCN2CCC(=O)NO	IC50 = 99000 nM	Poor binder
T51191	Histone deacetylase 2	BC52UT	2-Hexyl-N-hydroxy-N'-phenyloctanediamide	Investigative	134156853	C20H32N2O3	348.5	CCCCCCC(CCCCCC(=O)NC1=CC=CC=C1)C(=O)NO	IC50 = 180000 nM	Poor binder
T51191	Histone deacetylase 2	BC54SO	2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	136086920	C15H14N2O4S	318.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(C=C2)OCCO3	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BD5V4P	(1R,2R,3R)-N-Hydroxy-2-phenyl-3-quinoxalin-6-ylcyclopropane-1-carboxamide	Investigative	76324878	C18H15N3O2	305.3	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2C(=O)NO)C3=CC4=NC=CN=C4C=C3	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BD8NR5	(R)-6-(Benzenecarbonylamino)-7-(biphenyl-3-ylamino)-7-oxoheptylboronic acid	Investigative	42637300	C26H29BN2O4	444.3	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CC=CC=C3)(O)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BDCZ86	2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide	Investigative	135441620	C15H17N3O2S	303.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BDR0H9	8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide	Investigative	44359673	C16H24N2O3	292.37	CC(=O)N(CCCCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BE5WH2	N-Hydroxy-3-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide	Investigative	136030781	C15H14N4O2S	314.4	C1=CC(=CC(=C1)C(=O)NO)C2=CN(N=N2)CCC3=CSC=C3	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BE5WU6	N-Hydroxy-3-[2-(phenylsulfanylmethyl)-1,3-thiazol-4-yl]benzamide	Investigative	76853289	C17H14N2O2S2	342.4	C1=CC=C(C=C1)SCC2=NC(=CS2)C3=CC(=CC=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BF5DK4	2-(4-Hydroxybenzylidene)-1-benzofuran-3(2H)-one	Investigative	1798422	C15H10O3	238.24	C1=CC=C2C(=C1)C(=O)/C(=C/C3=CC=C(C=C3)O)/O2	IC50 = 100500 nM	Poor binder
T51191	Histone deacetylase 2	BFC08Z	2-[2-(4-Hydroxyphenyl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	135928628	C13H12N2O3S	276.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BFH13S	N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide	Investigative	135567459	C16H14N4O2S	326.4	C1=CC=C(C=C1)SCN2C=C(N=N2)C3=CC(=CC=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BFWZ34	Chembl4211116	Investigative	145965019	C25H24N4O5S	492.5	C1=CC=C(C=C1)CNC(=O)[C@H](CC2=CNC3=CC=CC=C32)NS(=O)(=O)C4=CC=CC(=C4)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BG09QH	N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide	Investigative	1108280	C16H17N3O2S	315.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BHB09K	2-(2,2-Dimethylpropanoyl)-N-hydroxy-1,3-dihydroisoindole-5-carboxamide	Investigative	58147224	C14H18N2O3	262.3	CC(C)(C)C(=O)N1CC2=C(C1)C=C(C=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BHGX52	6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-one	Investigative	135412194	C13H12N2O2S	260.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BI6ZB1	N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide	Investigative	136025986	C16H17N3O3S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)N(C)C(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BI97WY	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3,4,5-tetrahydro-2-benzazepine-7-carboxamide	Investigative	58147302	C17H19N3O3	313.35	CN1C=CC=C1C(=O)N2CCCC3=C(C2)C=CC(=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BJ1OD3	2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135473106	C11H16N2O2S	240.32	CC1=CC(=O)NC(=N1)SCC(=O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BJ2Y3N	2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135437514	C13H11ClN2O2S	294.76	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)Cl	IC50 = 67000 nM	Poor binder
T51191	Histone deacetylase 2	BKWJ62	Chembl4206647	Investigative	145975187	C15H15N3O5S	349.4	C1=CC=C(C=C1)NC(=O)CNS(=O)(=O)C2=CC=CC(=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BL3W7B	Chembl4214502	Investigative	145974125	C25H20N2O6S	476.5	COC1=CC=C(C=C1)C(=O)C2=CC3=C(C=C2)N(C=C3)S(=O)(=O)C4=CC=C(C=C4)/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BL5RX8	2-[5-(3-Nitrophenyl)furfuryl]-1,2,3,4-tetrahydroisoquinoline-7-carbohydroximic acid	Investigative	101882265	C21H19N3O5	393.4	C1CN(CC2=C1C=CC(=C2)C(=O)NO)CC3=CC=C(O3)C4=CC(=CC=C4)[N+](=O)[O-]	IC50 = 109000 nM	Poor binder
T51191	Histone deacetylase 2	BLBA30	2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone	Investigative	135449197	C14H14N2O3S	290.34	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BLBE28	(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-carbonylamino)heptylboronic acid	Investigative	42638004	C25H28BN3O4	445.3	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CN=CC=C3)(O)O	IC50 = 99000 nM	Poor binder
T51191	Histone deacetylase 2	BM9I8K	Chembl4165684	Investigative	145953085	C25H23N3O5	445.5	C1COCCN1C2=C3C=CC=C4C3=C(C=C2)C(=O)N(C4=O)CCC5=CC=C(C=C5)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BNJI96	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	Investigative	92045024	C20H19N5O2	361.4	C1CC2=C(C[C@@H]1NC3=NC=CC(=N3)C4=CN=CC=C4)C=C(C=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BO3VI5	Chembl4209492	Investigative	145964043	C18H26N2O2	302.4	C1CCC(CC1)C2C3=CC=CC=C3CCN2CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BO5I0U	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	136086924	C15H15N3O4	301.3	CC1=CC(=O)NC(=N1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BO8TP2	N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)hexyl)-2-mercaptoacetamide	Investigative	46907160	C26H43NO3S	449.7	C[C@H](CCCCNC(=O)CS)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 96300 nM	Poor binder
T51191	Histone deacetylase 2	BP01JN	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[2-[3-(hydroxyamino)-3-oxopropoxy]ethyl]benzamide	Investigative	134150479	C25H23F4N5O5S	581.5	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCOCCC(=O)NO)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 = 86500 nM	Poor binder
T51191	Histone deacetylase 2	BP9E6M	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide	Investigative	49831258	C16H17N3O3	299.32	CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BPM4U3	Chembl4213975	Investigative	145966296	C16H17N3O5S	363.4	C[C@@H](C(=O)NC1=CC=CC=C1)NS(=O)(=O)C2=CC=CC(=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BPR61J	[4-(Azidomethyl)phenyl]methyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate	Investigative	71449819	C30H33N7O5	571.6	COC1=CC(=CC(=C1)N=[N+]=[N-])COC2=CC=C(C=C2)NC(=O)CCCCCCC(=O)OCC3=CC=C(C=C3)CN=[N+]=[N-]	IC50 = 79000 nM	Poor binder
T51191	Histone deacetylase 2	BPRY15	Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate	Investigative	135412048	C8H10N2O3S	214.24	CC1=CC(=O)NC(=N1)SCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BQF23U	Chembl4202721	Investigative	145976000	C22H21N3O5S	439.5	C1=CC=C(C=C1)CNC(=O)[C@H](C2=CC=CC=C2)NS(=O)(=O)C3=CC=CC(=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BR6BY4	N-Hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]isoindoline-5-carboxamide	Investigative	58147189	C15H15N3O3	285.3	CN1C=CC=C1C(=O)N2CC3=C(C2)C=C(C=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BRGV98	1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanone	Investigative	135444536	C13H12N2O4S	292.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BS8PG9	2-(2,2-Dimethylpropanoyl)-N-hydroxy-3,4-dihydro-1H-isoquinoline-6-carboxamide	Investigative	49855444	C15H20N2O3	276.33	CC(C)(C)C(=O)N1CCC2=C(C1)C=CC(=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BT68SN	Chembl4208365	Investigative	132022730	C17H20N2O2	284.35	C1=CC=C(C=C1)CN(CCC(=O)NO)CC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BU2T0V	Methyl 7-anilino-7-oxoheptyl(hydroxy)carbamate	Investigative	44359814	C15H22N2O4	294.35	COC(=O)N(CCCCCCC(=O)NC1=CC=CC=C1)O	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BU45MK	3beta-[1-Oxo-2-(2,2,2-trifluoroethyl)isoindoline-5-yl]-2alpha-phenylcyclopropane-1alpha-carbohydroxamic acid	Investigative	60148690	C20H17F3N2O3	390.4	C1C2=C(C=CC(=C2)[C@@H]3[C@H]([C@H]3C(=O)NO)C4=CC=CC=C4)C(=O)N1CC(F)(F)F	IC50 ~ 50000 nM	Poor binder
T51191	Histone deacetylase 2	BUD52R	Chembl4218293	Investigative	145970069	C19H22N2O3	326.4	COC1=CC=C(C=C1)C2C3=CC=CC=C3CCN2CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BVSP75	6-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]-1,3-dihydroindol-2-one	Investigative	136086921	C15H13N3O3S	315.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(CC(=O)N3)C=C2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BW53QM	N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56673234	C16H17N3O3S	331.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)OC	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BWG03J	(E)-N-(2-Aminophenyl)-3-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorophenyl]prop-2-enamide	Investigative	134147087	C28H21F4N5O2S	567.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)/C=C/C(=O)NC3=CC=CC=C3N)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BX18GK	Ethyl 4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-3-oxobutanoate	Investigative	136086922	C11H14N2O4S	270.31	CCOC(=O)CC(=O)CSC1=NC(=CC(=O)N1)C	IC50 = 69300 nM	Poor binder
T51191	Histone deacetylase 2	BX62ZD	6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-one	Investigative	135407493	C11H10N2O2S2	266.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BX7HL2	Chembl4216233	Investigative	145974667	C12H18N2O2	222.28	C1=CC=C(C=C1)CNCCCCC(=O)NO	IC50 = 58000 nM	Poor binder
T51191	Histone deacetylase 2	BX8AF0	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]benzamide	Investigative	136025837	C20H17N3O3S	379.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BXWV29	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(3-hydroxy-2-oxopyridin-1-yl)hexyl]benzamide	Investigative	134142119	C31H29F4N5O4S	643.7	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCCCCN3C=CC=C(C3=O)O)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	BZ59WF	(R)-7-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)-N-methyl-2-oxooctanamide	Investigative	46906643	C27H43NO4	445.6	C[C@H](CCCCC(=O)C(=O)NC)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C3C[C@H](C[C@@H](C3)O)O)C	IC50 = 90400 nM	Poor binder
T51191	Histone deacetylase 2	BZE9S5	Chembl4206055	Investigative	145978561	C17H18N2O2	282.34	C1CN(C(C2=CC=CC=C21)C3=CC=CC=C3)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T51191	Histone deacetylase 2	D0Q5MC	PCI-34051	Investigative	24753719	C17H16N2O3	296.32	COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder