TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T51426	Farnesoid X-activated receptor	D0G3SH	Ursodeoxycholic acid	Approved	31401	C24H40O4	392.6	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 ~ 50000 nM	Poor binder
T51426	Farnesoid X-activated receptor	D0OR2L	Cholic Acid	Approved	221493	C24H40O5	408.6	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	D02PQB	ATX-101	Phase 3	222528	C24H40O4	392.6	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 = 50000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B09XOU	7-(4-Acetyl-2-ethyl-5-hydroxyphenoxy)-2,2-dimethylheptanoic acid	Investigative	14820108	C19H28O5	336.4	CCC1=CC(=C(C=C1OCCCCCC(C)(C)C(=O)O)O)C(=O)C	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B0I2OE	2-[(1S)-1-[4,4-Dimethyl-2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-3-methylbutyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137651721	C31H32N4O5	540.6	CC(C)C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)C(N(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5)(C)C	IC50 = 104600 nM	Poor binder
T51426	Farnesoid X-activated receptor	B0IVU3	(4R)-4-[(3R,6R,7R,8S,9S,10S,13R,14S)-3,7-Dihydroxy-6-(2-hydroxyethyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid	Investigative	76311393	C26H44O5	436.6	C[C@H](CCC(=O)O)C1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H]([C@@H](C4[C@@]3(CC[C@H](C4)O)C)CCO)O)C	EC50 = 61150 nM	Poor binder
T51426	Farnesoid X-activated receptor	B0TF3A	12-O-Deacetyl-12-epi-scalarin	Investigative	10960421	C25H38O4	402.6	C[C@]12CCCC([C@@H]1CC[C@@]3([C@@H]2C[C@H]([C@]4([C@H]3CC=C5[C@@H]4[C@@H](OC5=O)O)C)O)C)(C)C	IC50 = 75000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B10GSL	3-Tert-butyl-4-hydroxyphenyl phenylacetate	Investigative	836845	C18H20O3	284.3	CC(C)(C)C1=C(C=CC(=C1)OC(=O)CC2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B1ABU9	2-[(1S)-1-[3-(4-Cyclohexyloxyphenyl)-2,5-dioxoimidazolidin-1-yl]-3-methylbutyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137643657	C29H34N4O5	518.6	CC(C)C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5CCCCC5	IC50 = 125500 nM	Poor binder
T51426	Farnesoid X-activated receptor	B1OUA5	Guggulsterone	Investigative	6450278	C21H28O2	312.4	C/C=C/1\\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C	IC50 = 89360 nM	Poor binder
T51426	Farnesoid X-activated receptor	B1Q4BR	16-Epi-Avicholic Acid Sodium Salt	Investigative	70684311	C24H39NaO5	430.6	C[C@H](CCC(=O)[O-])[C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C)O.[Na+]	EC50 = 55000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B1SJN7	(4R,6S)-3-Methyl-1-(2-methylphenyl)-4-(4-phenoxyphenyl)-6-propyl-4,8-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one	Investigative	136226163	C29H29N3O2S	483.6	CCC[C@H]1C(=O)NC2=C([C@H](S1)C3=CC=C(C=C3)OC4=CC=CC=C4)C(=NN2C5=CC=CC=C5C)C	EC50 ~ 150000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B21CDS	2-[(1R)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137632414	C28H26N4O5	498.5	CC(C)[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 118500 nM	Poor binder
T51426	Farnesoid X-activated receptor	B3GEY6	2-[(1R)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-phenylethyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137653039	C32H26N4O5	546.6	CN1C2=C(C=CC(=C2)C(=O)O)N=C1[C@@H](CC3=CC=CC=C3)N4C(=O)CN(C4=O)C5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 87500 nM	Poor binder
T51426	Farnesoid X-activated receptor	B4KB3P	N-(3-Tert-Butyl-4-hydroxyphenyl)-2,6-dichloro-4-piperazinobenzamide	Investigative	122189005	C21H25Cl2N3O2	422.3	CC(C)(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2Cl)N3CCNCC3)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B5OHR7	2-[3-[(4-Methylphenyl)carbamoyl]-4-piperidin-1-ylphenyl]indazole-6-carboxylic acid	Investigative	102004339	C27H26N4O3	454.5	CC1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)N3C=C4C=CC(=CC4=N3)C(=O)O)N5CCCCC5	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B6A3SD	INT-777 R-enantiomer	Investigative	44605418	C27H46O5	450.7	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3C[C@@H]([C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)C[C@@H](C)C(=O)O)C)O)C)O	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B6D5RK	2-[(1S,2S)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylbutyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137659284	C29H28N4O5	512.6	CC[C@H](C)[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 102200 nM	Poor binder
T51426	Farnesoid X-activated receptor	B74XEQ	2-[(1S)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-3-methylbutyl]-1-methylbenzimidazole-5-carboxylic acid	Investigative	137632309	C29H28N4O5	512.6	CC(C)C[C@@H](C1=NC2=C(N1C)C=CC(=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 112900 nM	Poor binder
T51426	Farnesoid X-activated receptor	B7H5OM	(1R,5Bs,11aS,13R,13aS,13bS)-5b-(hydroxymethyl)-8,8,11a,13a-tetramethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-1,13-diol	Investigative	21778741	C25H40O4	404.6	C[C@]12CCCC(C1CC[C@@]3(C2C[C@H]([C@]4(C3CC=C5[C@@H]4[C@@H](OC5)O)C)O)CO)(C)C	IC50 = 64500 nM	Poor binder
T51426	Farnesoid X-activated receptor	B84WRZ	3-[(1S)-1-(1,6-Dimethylbenzimidazol-2-yl)-3-methylbutyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione	Investigative	137657016	C29H30N4O3	482.6	CC1=CC2=C(C=C1)N=C(N2C)[C@H](CC(C)C)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 65600 nM	Poor binder
T51426	Farnesoid X-activated receptor	B85XBG	(3-Tert-butyl-4-hydroxyphenyl) 2-methoxybenzoate	Investigative	122188980	C18H20O4	300.3	CC(C)(C)C1=C(C=CC(=C1)OC(=O)C2=CC=CC=C2OC)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B8GI4R	2-[(1S)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2,2-dimethylpropyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137661482	C29H28N4O5	512.6	CC(C)(C)[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 77100 nM	Poor binder
T51426	Farnesoid X-activated receptor	B8N3BQ	(E)-3-(3-{Cyclohexanecarbonyl-[4-((E)-3-ethoxy-propenyl)-benzyl]-amino}-phenyl)-acrylic acid methyl ester	Investigative	10885046	C29H35NO4	461.6	CCOC/C=C/C1=CC=C(C=C1)CN(C2=CC=CC(=C2)/C=C/C(=O)OC)C(=O)C3CCCCC3	EC50 = 198000 nM	Poor binder
T51426	Farnesoid X-activated receptor	B8PH4C	N-(3-Tert-butyl-4-prop-2-enoxyphenyl)-2,4-dichlorobenzamide	Investigative	122188992	C20H21Cl2NO2	378.3	CC(C)(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)OCC=C	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BA53DZ	(3-Tert-butyl-4-hydroxyphenyl) (E)-3-phenylprop-2-enoate	Investigative	122188872	C19H20O3	296.4	CC(C)(C)C1=C(C=CC(=C1)OC(=O)/C=C/C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BA68UM	N-(3-Tert-Butyl-4-hydroxyphenyl)-2,6-dichloro-4-piperidinobenzamide	Investigative	122189004	C22H26Cl2N2O2	421.4	CC(C)(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2Cl)N3CCCCC3)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BAE89C	Chembl4202981	Investigative	71599441	C36H42Cl2N4O8S	761.7	C1CC1N2CCN(C3=CC=CC=C32)C(=O)[C@@H]4CSCN4CC5=CC(=C(C=C5Cl)OCC6=CC=C(C=C6)C(=O)NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)Cl	EC50 ~ 50118.72 nM	Poor binder
T51426	Farnesoid X-activated receptor	BBI48M	(3-Tert-butyl-4-hydroxyphenyl) benzoate	Investigative	836814	C17H18O3	270.32	CC(C)(C)C1=C(C=CC(=C1)OC(=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BBQ51V	3alpha,7alpha,12alpha-Trihydroxy-6alpha-ethyl-5beta-cholan-24-oic acid	Investigative	9910920	C26H44O5	436.6	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3C[C@@H]([C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)O)C)O	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BC3SO2	12-O-Deacetyl-12-epi-19-deoxy-22-hydroxyscalarin	Investigative	24178657	C25H38O4	402.6	C[C@@]1(CCC[C@]2([C@H]1CC[C@@]3([C@@H]2C[C@H]([C@]4([C@H]3CC=C5[C@@H]4COC5=O)C)O)C)C)CO	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BCZI32	(2S,4R)-4-[(3R,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid	Investigative	44427760	C25H42O4	406.6	C[C@H](C[C@H](C)C(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](CC4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BD93FS	Chembl4170402	Investigative	101680021	C30H50O10	570.7	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)O)C	EC50 = 91500 nM	Poor binder
T51426	Farnesoid X-activated receptor	BE39AU	N-(3-Tert-Butyl-4-hydroxyphenyl)-2,6-dichloro-4-(methylcyclohexylamino)benzamide	Investigative	122189003	C24H30Cl2N2O2	449.4	CC(C)(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2Cl)N(C)C3CCCCC3)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BEP50Y	Chembl4160865	Investigative	145957191	C31H33N5O3	523.6	CC1=CC2=C(C=C1)N=C(N2C)[C@H](CC3CCNCC3)N4C(=O)CN(C4=O)C5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 64000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BF4AE5	2,4-Dichloro-N-(3-ethyl-4-hydroxyphenyl)benzamide	Investigative	122188990	C15H13Cl2NO2	310.2	CCC1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BF56BT	2-[(1S)-1-[3-[4-(4-Methoxyphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]-3-methylbutyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137634692	C30H30N4O6	542.6	CC(C)C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=C(C=C5)OC	IC50 = 75300 nM	Poor binder
T51426	Farnesoid X-activated receptor	BGAR17	3-Tert-butyl-4-hydroxyphenyl 4-methylbenzoate	Investigative	836804	C18H20O3	284.3	CC1=CC=C(C=C1)C(=O)OC2=CC(=C(C=C2)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BHC49B	2,4-Dichloro-N-(3,5-ditert-butyl-4-hydroxyphenyl)benzamide	Investigative	122188988	C21H25Cl2NO2	394.3	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BHW49B	N-(3-Tert-butyl-4-methoxyphenyl)-2,4-dichlorobenzamide	Investigative	122188991	C18H19Cl2NO2	352.3	CC(C)(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BHZ6C4	(4S,6R)-3,6-Dimethyl-1-(2-methylphenyl)-4-(4-phenoxyphenyl)-4,8-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one	Investigative	136226158	C27H25N3O2S	455.6	C[C@@H]1C(=O)NC2=C([C@@H](S1)C3=CC=C(C=C3)OC4=CC=CC=C4)C(=NN2C5=CC=CC=C5C)C	EC50 ~ 150000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BIL5W6	2,4-Dichloro-N-(4-hydroxy-3-propan-2-ylphenyl)benzamide	Investigative	122188989	C16H15Cl2NO2	324.2	CC(C)C1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BN37EZ	(4R,6S)-6-Methyl-1-(2-methylphenyl)-4-(4-phenoxyphenyl)-4,8-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one	Investigative	136226161	C26H23N3O2S	441.5	C[C@H]1C(=O)NC2=C(C=NN2C3=CC=CC=C3C)[C@H](S1)C4=CC=C(C=C4)OC5=CC=CC=C5	EC50 ~ 150000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BO17TX	Chembl4205214	Investigative	71660821	C22H23Cl2N3OS	448.4	C1CC1N2CCN(C3=CC=CC=C32)C(=O)[C@@H]4CSCN4CC5=C(C=CC(=C5)Cl)Cl	EC50 ~ 50118.72 nM	Poor binder
T51426	Farnesoid X-activated receptor	BR2M7U	N-(3-Tert-butyl-4-hydroxyphenyl)-2,6-dichloro-N-cyclohexyl-4-(dimethylamino)benzamide	Investigative	122189009	C25H32Cl2N2O2	463.4	CC(C)(C)C1=C(C=CC(=C1)N(C2CCCCC2)C(=O)C3=C(C=C(C=C3Cl)N(C)C)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BR7LK9	Chembl4160181	Investigative	101680020	C30H50O9	554.7	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)C	EC50 = 76000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BRK79D	(3-Tert-butyl-4-hydroxyphenyl) 4-chlorobenzoate	Investigative	836818	C17H17ClO3	304.8	CC(C)(C)C1=C(C=CC(=C1)OC(=O)C2=CC=C(C=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BROV48	N-(3-Tert-butyl-4-hydroxyphenyl)-2,6-dichloro-N-(cyclohexylmethyl)-4-(dimethylamino)benzamide	Investigative	122189008	C26H34Cl2N2O2	477.5	CC(C)(C)C1=C(C=CC(=C1)N(CC2CCCCC2)C(=O)C3=C(C=C(C=C3Cl)N(C)C)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BT1EO4	3-Tert-butyl-4-hydroxyphenyl 2-methylbenzoate	Investigative	836830	C18H20O3	284.3	CC1=CC=CC=C1C(=O)OC2=CC(=C(C=C2)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BTF5E1	(4R)-4-[(5S,7S,8R,9S,10S,13R,14S,17R)-7-Ethyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid	Investigative	44457504	C26H44O2	388.6	CC[C@H]1C[C@@H]2CCCC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@@H]([C@]4(CC3)C)[C@H](C)CCC(=O)O)C	EC50 ~ 50000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BU09QA	(4S,6S)-3,6-Dimethyl-1-(2-methylphenyl)-4-(4-phenoxyphenyl)-4,8-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one	Investigative	136226153	C27H25N3O2S	455.6	C[C@H]1C(=O)NC2=C([C@@H](S1)C3=CC=C(C=C3)OC4=CC=CC=C4)C(=NN2C5=CC=CC=C5C)C	EC50 ~ 150000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BU5J4A	2-[(1S)-1-[2,5-Dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxylic acid	Investigative	137653377	C28H26N4O5	498.5	CC(C)[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)O)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 174500 nM	Poor binder
T51426	Farnesoid X-activated receptor	BU70BN	3-Tert-butyl-4-hydroxyphenyl 2-furoate	Investigative	836832	C15H16O4	260.279	CC(C)(C)C1=C(C=CC(=C1)OC(=O)C2=CC=CO2)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BUCN36	3 alpha-Hydroxy-7 alpha-fluoro-5 beta-cholan-24-oic a	Investigative	44457471	C24H39FO3	394.6	C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)F)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BUQJ93	3-[(1S)-2-Cyclohexyl-1-(1,6-dimethylbenzimidazol-2-yl)ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione	Investigative	132938263	C32H34N4O3	522.6	CC1=CC2=C(C=C1)N=C(N2C)[C@H](CC3CCCCC3)N4C(=O)CN(C4=O)C5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 126100 nM	Poor binder
T51426	Farnesoid X-activated receptor	BVT9G5	Chembl4217797	Investigative	145974037	C33H45Cl2N5O7S	726.7	C1CC1N2CCN(C3=CC=CC=C32)C(=O)[C@@H]4CSCN4CC5=C(C=C(C(=C5)Cl)CCCCNC(=O)NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)Cl	EC50 ~ 50118.72 nM	Poor binder
T51426	Farnesoid X-activated receptor	BW4QI1	(2S,4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-Dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2-methylpentanoic acid	Investigative	17755103	C25H42O4	406.6	C[C@H](C[C@H](C)C(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BX07ER	3alpha,7beta-Dihydroxy-5beta-cholane-24-sulfonic acid	Investigative	10479586	C24H42O5S	442.7	C[C@H](CCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BXL40C	Avicholic Acid Sodium Salt	Investigative	70682209	C24H39NaO5	430.6	C[C@H](CCC(=O)[O-])[C@H]1[C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C)O.[Na+]	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BXZ81C	2,4-Dichloro-N-(4-hydroxy-3-methylphenyl)benzamide	Investigative	81567254	C14H11Cl2NO2	296.1	CC1=C(C=CC(=C1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)O	IC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BY3P4R	(4R,6R)-3,6-Dimethyl-1-(2-methylphenyl)-4-(4-phenoxyphenyl)-4,8-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one	Investigative	136226157	C27H25N3O2S	455.6	C[C@@H]1C(=O)NC2=C([C@H](S1)C3=CC=C(C=C3)OC4=CC=CC=C4)C(=NN2C5=CC=CC=C5C)C	EC50 ~ 150000 nM	Poor binder
T51426	Farnesoid X-activated receptor	BY7M6Z	(1R,5Br,11aS,13R,13aS,13bS)-1-hydroxy-5b,8,8,11a,13a-pentamethyl-1,3,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrochryseno[2,1-c]furan-13-yl acetate	Investigative	25118391	C27H42O4	430.6	CC(=O)O[C@@H]1CC2[C@]3(CCCC(C3CC[C@]2(C4[C@]1([C@H]5[C@@H](OCC5=CC4)O)C)C)(C)C)C	IC50 = 81100 nM	Poor binder
T51426	Farnesoid X-activated receptor	BY8MD6	12-Epi-scalarin	Investigative	10343437	C27H40O5	444.6	CC(=O)O[C@@H]1C[C@@H]2[C@]3(CCCC([C@@H]3CC[C@]2([C@H]4[C@]1([C@H]5[C@@H](OC(=O)C5=CC4)O)C)C)(C)C)C	IC50 = 60400 nM	Poor binder
T51426	Farnesoid X-activated receptor	BZ62MI	3alpha,7alpha-Dihydroxy-5beta-cholane-24-sulfonic acid	Investigative	21121407	C24H42O5S	442.7	C[C@H](CCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C	EC50 ~ 100000 nM	Poor binder
T51426	Farnesoid X-activated receptor	D0B7AH	INT-777	Investigative	45483949	C27H46O5	450.7	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3C[C@@H]([C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)C[C@H](C)C(=O)O)C)O)C)O	EC50 ~ 100000 nM	Poor binder