TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T53904	HIF-prolyl hydroxylase 1	D09NCT	PMID25468267-Compound-46	Patented	53392492	C27H29N3O6	491.5	C1=CC=C2C(=C1)C=CC=C2NC(=O)OCC3=CC=C(C=C3)CNCCCCN(C(=O)/C=C/C(=O)O)O	IC50 = 54000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B1XOP0	4-[8-(Dimethylamino)octyl-hydroxyamino]-4-oxobutanoic acid;hydrochloride	Investigative	46899762	C14H29ClN2O4	324.84	CN(C)CCCCCCCCN(C(=O)CCC(=O)O)O.Cl	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B3LY5A	N-[(3-Hydroxypyridin-2-Yl)carbonyl]glycine	Investigative	9837038	C8H8N2O4	196.16	C1=CC(=C(N=C1)C(=O)NCC(=O)O)O	IC50 = 91090 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B4XIA3	5-(3-Methylphenyl)-[1,2,4]triazolo[1,5-a]pyridine	Investigative	137642369	C13H11N3	209.25	CC1=CC(=CC=C1)C2=CC=CC3=NC=NN32	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B5ACQ1	4-(8-Methyl-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile	Investigative	137641310	C14H10N4	234.26	CC1=CC=C(N2C1=NC=N2)C3=CC=C(C=C3)C#N	IC50 = 80000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B6MT2O	3-[9-(Dimethylamino)nonanoyl-hydroxyamino]propanoic acid	Investigative	46899607	C14H28N2O4	288.38	CN(C)CCCCCCCCC(=O)N(CCC(=O)O)O	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B7E2SD	3-([1,2,4]Triazolo[1,5-a]pyridin-5-yl)benzonitrile	Investigative	137661677	C13H8N4	220.23	C1=CC(=CC(=C1)C2=CC=CC3=NC=NN32)C#N	IC50 = 61000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B8GH4U	5-(2-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridine	Investigative	137637795	C13H11N3O	225.25	COC1=CC=CC=C1C2=CC=CC3=NC=NN32	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	B96KDG	3-({9-[Butyl(Methyl)]Amino}Nonanoyl(Hydroxy)Amino)Propanoicacid HCl	Investigative	46899764	C17H35ClN2O4	366.9	CCCCN(C)CCCCCCCCC(=O)N(CCC(=O)O)O.Cl	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BB0DO4	5-(3-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridine	Investigative	137636671	C13H11N3O	225.25	COC1=CC=CC(=C1)C2=CC=CC3=NC=NN32	IC50 = 55000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BHS25Q	3-[9-(Dimethylamino)nonanoyl-hydroxyamino]propanoic acid;hydrochloride	Investigative	46899606	C14H29ClN2O4	324.84	CN(C)CCCCCCCCC(=O)N(CCC(=O)O)O.Cl	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BNA94M	3-[10-(Dimethylamino)decanoyl-hydroxyamino]propanoic acid;hydrochloride	Investigative	46899608	C15H31ClN2O4	338.87	CN(C)CCCCCCCCCC(=O)N(CCC(=O)O)O.Cl	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BOG9T4	7-(2,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidine	Investigative	137633446	C12H7Cl2N3	264.11	C1=CC(=C(C=C1Cl)Cl)C2=CC=NC3=CC=NN23	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BQBO01	3-[8-(Dimethylamino)octanoyl-hydroxyamino]propanoic acid;hydrochloride	Investigative	46899604	C13H27ClN2O4	310.82	CN(C)CCCCCCCC(=O)N(CCC(=O)O)O.Cl	IC50 ~ 100000 nM	Poor binder
T53904	HIF-prolyl hydroxylase 1	BRWX50	3-[Acetyl(hydroxy)amino]propanoic acid	Investigative	22959876	C5H9NO4	147.13	CC(=O)N(CCC(=O)O)O	IC50 ~ 100000 nM	Poor binder