TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T54128	Glutamate receptor AMPA	B16SZR	7,8-Dichlorotetrazolo[1,5-a]quinoxalin-4(5H)-one	Investigative	10244106	C8H3Cl2N5O	256.05	C1=C2C(=CC(=C1Cl)Cl)N3C(=NN=N3)C(=O)N2	IC50 ~ 100000 nM	Poor binder
T54128	Glutamate receptor AMPA	B3T4OA	2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	Investigative	10658567	C8H10N6O4	254.2	CN1C(=NN=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 = 54000 nM	Poor binder
T54128	Glutamate receptor AMPA	B78CPE	(3S,4Ar,6S,8aR)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3,6-dicarboxylic acid	Investigative	10656900	C11H17NO4	227.26	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T54128	Glutamate receptor AMPA	B7S9JZ	(3s,4Ar,6r,8ar)-6-(2h-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	10538709	C11H17N5O2	251.29	C1C[C@H]2CN[C@@H](C[C@H]2C[C@@H]1C3=NNN=N3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T54128	Glutamate receptor AMPA	B9F7YG	(3s,4Ar,6s,8ar)-6-(2h-tetrazol-5-ylmethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	10084218	C12H19N5O2	265.31	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CC3=NNN=N3)C(=O)O	IC50 = 84500 nM	Poor binder
T54128	Glutamate receptor AMPA	BGN92D	(3s,4Ar,6s,8ar)-6-(2h-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	9837860	C11H17N5O2	251.29	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1C3=NNN=N3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T54128	Glutamate receptor AMPA	BMH0S9	2-Amino-3-[3-oxo-5-(2H-tetrazol-5-yl)-1,2-oxazol-4-yl]propanoic Acid	Investigative	10800053	C7H8N6O4	240.18	C(C1=C(ONC1=O)C2=NNN=N2)C(C(=O)O)N	IC50 = 72000 nM	Poor binder
T54128	Glutamate receptor AMPA	BSBI56	alpha-Amino-3-carboxymethoxy-5-methyl-4-isoxazolepropionic acid	Investigative	125406	C9H12N2O6	244.2	CC1=C(C(=NO1)OCC(=O)O)CC(C(=O)O)N	IC50 = 88000 nM	Poor binder
T54128	Glutamate receptor AMPA	BU27PT	2-Amino-3-[5-(1-methylimidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10610792	C10H12N4O4	252.23	CN1C=CN=C1C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T54128	Glutamate receptor AMPA	D04DHB	5,7-Dichlorokynurenic Acid	Investigative	1779	C10H5Cl2NO3	258.05	C1=C(C=C(C2=C1NC(=CC2=O)C(=O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder