TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T55948	Organic cation transporter 3	D03SKR	Clonidine	Approved	2803	C9H9Cl2N3	230.09	C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl	IC50 = 79300 nM	Poor binder
T55948	Organic cation transporter 3	D04USC	Ergotidine	Approved	774	C5H9N3	111.15	C1=C(NC=N1)CCN	Ki = 140000 nM	Poor binder
T55948	Organic cation transporter 3	D07HOB	Irinotecan	Approved	60838	C33H38N4O6	586.7	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7	IC50 = 74600 nM	Poor binder
T55948	Organic cation transporter 3	D0R3JB	Mitoxantrone	Approved	4212	C22H28N4O6	444.5	C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO	IC50 = 60500 nM	Poor binder
T55948	Organic cation transporter 3	D0T6XX	Pantoprazole	Approved	4679	C16H15F2N3O4S	383.4	COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC	IC50 = 137000 nM	Poor binder
T55948	Organic cation transporter 3	B5O3JK	1-Phenylguanidine	Investigative	16157	C7H9N3	135.17	C1=CC=C(C=C1)N=C(N)N	IC50 = 99800 nM	Poor binder
T55948	Organic cation transporter 3	B6VDN2	Nifekalant	Investigative	4486	C19H27N5O5	405.4	CN1C(=CC(=O)N(C1=O)C)NCCN(CCCC2=CC=C(C=C2)[N+](=O)[O-])CCO	IC50 = 146000 nM	Poor binder
T55948	Organic cation transporter 3	D09HLX	MPP+	Investigative	39484	C12H12N+	170.23	C[N+]1=CC=C(C=C1)C2=CC=CC=C2	Ki = 54000 nM	Poor binder