TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T59190 Protein kinase C zeta D0E6XR Dasatinib Approved 3062316 C22H26ClN7O2S 488 CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta D0W3LI LY333531 Phase 2 153999 C28H28N4O3 468.5 CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta D0WS1V L-751250 Preclinical 448991 C20H25ClN6O3 432.9 CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=C(C=C3)C(=O)O)Cl IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B04BQN 3-[1-(1-Benzyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione Investigative 9958125 C33H30N4O2 514.6 CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=C7 IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B0WLH8 N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide Investigative 58056356 C17H12N4O2S 336.4 COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43 IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B0Y8JV 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-4-acetyl-2-(4-hydroxy-benzoylamino)-cyclopentyl ester Investigative 44315123 C29H25NO11 563.5 CC(=O)C1C[C@H]([C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta B0Z3SH 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methylcarbamoyl-cyclopentyl ester Investigative 44315423 C29H26N2O11 578.5 CNC(=O)C1C[C@H]([C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B18ZRL 2-[2,6-Dihydroxy-4-[(3R,4R)-3-[(4-hydroxybenzoyl)amino]thiepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid Investigative 44308467 C28H25NO10S 567.6 C1C[C@H]([C@H](CSC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 = 121000 nM Poor binder T59190 Protein kinase C zeta B1BZK4 2-(2,6-Dihydroxy-4-{[(1S,2R)-2-(4-hydroxy-benzoylamino)-cyclopentylmethyl]-carbamoyl}-benzoyl)-3-hydroxy-benzoic acid Investigative 15297224 C28H26N2O9 534.5 C1C[C@H]([C@@H](C1)NC(=O)C2=CC=C(C=C2)O)CNC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B3E1KR 2-[2,6-Dihydroxy-4-[[3-[(4-hydroxybenzoyl)amino]-1-azabicyclo[3.2.2]nonan-4-yl]oxycarbonyl]benzoyl]-3-hydroxybenzoic acid Investigative 23366085 C30H28N2O10 576.5 C1CN2CCC1C(C(C2)NC(=O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B4CSK5 4-(4-Methyl-1H-indole-5-ylamino)-5-[5-(4-methylpiperazinomethyl)benzofuran-2-yl]pyridine-3-carbonitrile Investigative 23627212 C29H28N6O 476.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3C#N)C4=CC5=C(O4)C=CC(=C5)CN6CCN(CC6)C IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B4EV7N 5-Vinyl-3-pyridinecarbonitrile, 14b Investigative 44473011 C24H28N6 400.5 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/CCN4CCC(CC4)N)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B4F1NE 2-[2,6-Dihydroxy-4-[[(3R,4S)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]-methylcarbamoyl]benzoyl]-3-hydroxybenzoic acid Investigative 71718528 C29H29N3O9 563.6 CN([C@H]1CCCNC[C@H]1NC(=O)C2=CC=C(C=C2)O)C(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B4ZO0T 5-Vinyl-3-pyridinecarbonitrile, 13b Investigative 44473009 C23H26N6 386.5 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/CCN4CCNCC4)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B58TMC [6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate Investigative 24753787 C21H22ClN3O6S 479.9 CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta B5J3GY 5-Vinyl-3-pyridinecarbonitrile, 19 Investigative 44160269 C24H28N6 400.5 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/CCN4CCC[C@H](C4)N)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B5NSE7 4-(4-Methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile Investigative 45375865 C28H28N6O2S 512.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B6MJU3 Balanol analog 3 Investigative 5327920 C27H24N2O10 536.5 C1CNC[C@H]([C@@H]1OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta B6N0XK 5-Vinyl-3-pyridinecarbonitrile, 24 Investigative 44473016 C25H30N6O2S 478.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/CCN4CCC(CC4)NS(=O)(=O)C)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B6XSK7 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-(2,2,2-trifluoro-acetyl)-cyclopentyl ester Investigative 44315122 C29H22F3NO11 617.5 C1[C@H]([C@@H](CC1C(=O)C(F)(F)F)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 = 56000 nM Poor binder T59190 Protein kinase C zeta B73OKA 1-((5-(3-Ethynyl-2-((4-methyl-1H-inden-5-yl)methyl)phenyl)furan-2-yl)methyl)-4-methylpiperazine Investigative 45487634 C29H30N2O 422.6 CC1=C(C=CC2=C1C=CC2)CC3=C(C=CC=C3C4=CC=C(O4)CN5CCN(CC5)C)C#C IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta B7XFG2 (18S)-18-(Pyrrolidin-1-ylmethyl)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione Investigative 11799388 C30H30N4O3 494.6 C1CCN(C1)C[C@@H]2CCN3C=C(C4=CC=CC=C43)C5=C(C6=CN(CCO2)C7=CC=CC=C76)C(=O)NC5=O IC50 = 55000 nM Poor binder T59190 Protein kinase C zeta B9PA0T 3-(1-Methyl-1H-indole-3-yl)-4-[1-(1-benzylpyrrolidine-3-yl)-1H-indole-3-yl]-1H-pyrrole-2,5-dione Investigative 10940039 C32H28N4O2 500.6 CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(C6)CC7=CC=CC=C7 IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BA62QX 4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile Investigative 24766030 C24H21N5OS 427.5 CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5 IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BAN67W 2-[2,6-Dihydroxy-4-[[(1R,2R)-2-[(4-hydroxybenzoyl)amino]cyclopentyl]methoxycarbonyl]benzoyl]-3-hydroxybenzoic acid Investigative 15297223 C28H25NO10 535.5 C1C[C@H]([C@@H](C1)NC(=O)C2=CC=C(C=C2)O)COC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BAVW57 4-(4-Methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile Investigative 24825721 C28H30N6O 466.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3C#N)C4=CC=C(C=C4)OCCN5CCN(CC5)C IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BBZ7W1 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methanesulfonyl-cyclopentyl ester Investigative 44315457 C28H25NO12S 599.6 CS(=O)(=O)C1C[C@H]([C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BDA6R9 3-(1-Methyl-1H-indole-3-yl)-4-[1-[1-(tert-butoxycarbonyl)piperidine-4-yl]-1H-indole-3-yl]-1H-pyrrole-2,5-dione Investigative 10864309 C31H32N4O4 524.6 CC(C)(C)OC(=O)N1CCC(CC1)N2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CN(C6=CC=CC=C65)C IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BF5D9C 3-Hydroxy-2-[2,6-dihydroxy-4-[[[[3beta-[(4-hydroxybenzoyl)amino]hexahydrothiepin]-4alpha-yl]oxy]carbonyl]benzoyl]benzoic acid Investigative 10099482 C28H25NO10S 567.6 C1C[C@H]([C@@H](CSC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 = 121000 nM Poor binder T59190 Protein kinase C zeta BF9OW5 2-[2,6-Dihydroxy-4-[(3S,4R)-3-[(4-hydroxybenzoyl)amino]-1,1-dioxothiepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid Investigative 10555532 C28H25NO12S 599.6 C1C[C@H]([C@@H](CS(=O)(=O)C1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BIK40W 2-[2,6-Dihydroxy-4-[[9-[(4-hydroxybenzoyl)amino]-8-tricyclo[5.2.1.02,6]decanyl]oxycarbonyl]benzoyl]-3-hydroxybenzoic acid Investigative 44310795 C32H29NO10 587.6 C1CC2C(C1)C3CC2C(C3OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O)NC(=O)C6=CC=C(C=C6)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BJ7M1X 5-(3,4-Dimethoxyphenyl)-4-(1H-indol-5-ylamino)pyridine-3-carbonitrile Investigative 24770517 C22H18N4O2 370.4 COC1=C(C=C(C=C1)C2=C(C(=CN=C2)C#N)NC3=CC4=C(C=C3)NC=C4)OC IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BKX51S 4-(4-Methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylpiperazin-1-yl)ethoxy)styryl)nicotinonitrile Investigative 45485083 C30H32N6O 492.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/C4=CC(=CC=C4)OCCN5CCN(CC5)C)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BL0IA1 (R)-2-{2,6-Dihydroxy-4-[3-(4-hydroxy-benzoylamino)-azepan-4-ylcarbamoyl]-benzoyl}-3-hydroxy-benzoic acid Investigative 44303745 C28H27N3O9 549.5 C1C[C@H]([C@@H](CNC1)NC(=O)C2=CC=C(C=C2)O)NC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BL4G8Z 2-[2,6-Dihydroxy-4-[(3R,4R)-3-[(4-hydroxybenzoyl)amino]-1,1-dioxothiepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid Investigative 44308468 C28H25NO12S 599.6 C1C[C@H]([C@H](CS(=O)(=O)C1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BMKW53 2-[2,6-Dihydroxy-4-[(3S,4R)-3-[(4-hydroxybenzoyl)amino]oxepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid Investigative 44308409 C28H25NO11 551.5 C1C[C@H]([C@H](COC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BMTS94 6-Methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile Investigative 45375866 C29H30N6O2S 526.7 CC1=C(C=CC2=C1C=CN2)NC3=C(C(=NC=C3C#N)C)/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BNC70Q 3-Hydroxy-2-[2,6-dihydroxy-4-[[[[3beta-[(4-hydroxybenzoyl)amino]hexahydrooxepin]-4alpha-yl]oxy]carbonyl]benzoyl]benzoic acid Investigative 10030483 C28H25NO11 551.5 C1C[C@H]([C@@H](COC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BP32RV 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2S)-2-(4-hydroxy-benzoylamino)-cycloheptyl ester Investigative 44308469 C29H27NO10 549.5 C1CC[C@@H]([C@@H](CC1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BQY8U1 2-[2,6-Dihydroxy-4-[[3-[(4-hydroxybenzoyl)amino]-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]oxycarbonyl]benzoyl]-3-hydroxybenzoic acid Investigative 11972484 C32H31NO10 589.6 CC1(C2CCC1(C(C2NC(=O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O)C)C IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BRBH81 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3S,4S)-3-(4-hydroxy-benzoylamino)-azepan-4-yl ester Investigative 10554684 C28H26N2O10 550.5 C1C[C@@H]([C@H](CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BRSZ96 2-[2,6-Dihydroxy-4-[(1R,2R)-2-[(4-hydroxybenzoyl)amino]cycloheptyl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid Investigative 5327919 C29H27NO10 549.5 C1CC[C@H]([C@@H](CC1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BS8N0G 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methoxycarbonyl-cyclopentyl ester Investigative 44315545 C29H25NO12 579.5 COC(=O)C1C[C@H]([C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 150000 nM Poor binder T59190 Protein kinase C zeta BSW7M0 2-[2,6-Dihydroxy-4-[[3-[(4-hydroxybenzoyl)amino]-2-bicyclo[2.2.1]heptanyl]oxycarbonyl]benzoyl]-3-hydroxybenzoic acid Investigative 5327923 C29H25NO10 547.5 C1CC2CC1C(C2OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O)NC(=O)C5=CC=C(C=C5)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BT9VH6 6-(2,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine Investigative 70789255 C14H20N6 272.35 C1CC2(CCN(CC2)C3=NC=NC4=C3NC=N4)CNC1 IC50 = 74000 nM Poor binder T59190 Protein kinase C zeta BUY1S6 Purvalanol A Investigative 456214 C19H25ClN6O 388.9 CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC=C3)Cl IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BV2L3R 4-(6-Chloro-4-methyl-1H-benzimidazol-2-yl)-3-(4-chlorophenyl)butanoic acid Investigative 45381093 C18H16Cl2N2O2 363.2 CC1=CC(=CC2=C1N=C(N2)CC(CC(=O)O)C3=CC=C(C=C3)Cl)Cl IC50 = 55000 nM Poor binder T59190 Protein kinase C zeta BVS35M (18S)-18-[(Benzylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione Investigative 10768554 C33H30N4O3 530.6 C1CN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO[C@@H]1CNCC6=CC=CC=C6)C7=CC=CC=C75)C(=O)NC4=O IC50 = 54000 nM Poor binder T59190 Protein kinase C zeta BVXM96 US8889672, Apogee B Investigative 71009778 C17H16ClNO4S 365.8 CCOC(=O)C1=C(SC(=C1C2=CC=C(C=C2)Cl)C(=O)C)NC(=O)C IC50 = 71000 nM Poor binder T59190 Protein kinase C zeta BW0IH8 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 2-(4-hydroxy-benzoylamino)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester Investigative 23366090 C30H28N2O10 576.5 CN1C2CCC1C(C(C2)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O)NC(=O)C5=CC=C(C=C5)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BWT35H 5-Vinyl-3-pyridinecarbonitrile, 13a Investigative 44251637 C22H24N6 372.5 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/CN4CCNCC4)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BY8UA9 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (2R,3R)-3-(4-hydroxy-benzoylamino)-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester Investigative 44315184 C32H31NO10 589.6 CC1(C2CCC1([C@H]([C@@H]2NC(=O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O)C)C IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta BZ70DC (E)-4-(4-Methyl-1H-indol-5-ylamino)-5-(2-(6-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)vinyl)nicotinonitrile Investigative 46846072 C28H29N7 463.6 CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/C4=CC=CC(=N4)CN5CCN(CC5)C)C#N IC50 ~ 100000 nM Poor binder T59190 Protein kinase C zeta BZA3F7 Modified Benzophenone Ring, Balanol Analog 20 Investigative 5327979 C27H25NO9 507.5 C1C[C@H]([C@@H](C1)OCC2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)NC(=O)C4=CC=C(C=C4)O IC50 ~ 50000 nM Poor binder T59190 Protein kinase C zeta D02XHC aloisine A Investigative 448912 C16H17N3O 267.33 CCCCC1=C(NC2=NC=CN=C12)C3=CC=C(C=C3)O IC50 ~ 100000 nM Poor binder