TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T60529	Prostaglandin G/H synthase 1	D05VLS	Rofecoxib	Approved	5090	C17H14O4S	314.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3	IC50 = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D09MGR	Etoricoxib	Approved	123619	C18H15ClN2O2S	358.8	CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 98800 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0GY5Z	Aspirin	Approved	2244	C9H8O4	180.16	CC(=O)OC1=CC=CC=C1C(=O)O	Ki = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0IT2X	Carprofen	Approved	2581	C15H12ClNO2	273.71	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O	IC50 = 59000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0L6DA	Valdecoxib	Approved	119607	C16H14N2O3S	314.4	CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0U5QK	Acetaminophen	Approved	1983	C8H9NO2	151.16	CC(=O)NC1=CC=C(C=C1)O	IC50 = 200000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D00QOF	ORG-13011	Phase 2	44473151	C38H43N3O4S	637.8	CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)O)SC(C)(C)C	IC50 = 58000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0L4FS	Genistein	Phase 2	5280961	C15H10O5	270.24	C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O	IC50 = 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0E2TY	Indomethacin analog 3	Patented	71523527	C21H21ClN2O5S	448.9	CC1=C(N(C2=C1C=C(C=C2)OC)C(=O)C3=CC=C(C=C3)Cl)CCC(=O)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0KP0U	PMID26394986-Compound-22	Patented	2662	C17H14F3N3O2S	381.4	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0M6LX	N-(naphthylamino)-benzoate derivative 1	Patented	56851703	C17H12N2O4	308.29	C1=CC=C2C(=C1)C(=CC=C2[N+](=O)[O-])NC3=CC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0SG9Q	US9388139, 12	Patented	60194756	C20H20Cl2N2O2	391.3	CC(C)(C)C1=NN(C(C1)C2=C(C=C(C=C2)Cl)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0C0JT	Nimesulide	Withdrawn from market	4495	C13H12N2O5S	308.31	CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2	IC50 = 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D00RSK	GW-406381	Discontinued in Phase 3	9832687	C21H19N3O3S	393.5	CCOC1=CC=C(C=C1)C2=NN3C(=C2C4=CC=C(C=C4)S(=O)(=O)C)C=CC=N3	IC50 ~ 84200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D07HBI	ZD-2138	Discontinued in Phase 2	132306	C23H24FNO4	397.4	CN1C2=C(C=CC1=O)C=C(C=C2)COC3=CC(=CC(=C3)C4(CCOCC4)OC)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0Z5LZ	Tilmacoxib	Discontinued in Phase 2	159271	C16H19FN2O3S	338.4	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)F)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D02OHR	SC-57666	Discontinued in Phase 1	443373	C18H17FO2S	316.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D05EYG	L-745337	Terminated	9799453	C16H13F2NO3S2	369.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=C(C=C(C=C3)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D05REH	Flosulide	Terminated	71246	C16H13F2NO4S	353.3	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)OC3=C(C=C(C=C3)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D07TZM	SC-58125	Terminated	115239	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D09BKE	NS398	Terminated	4553	C13H18N2O5S	314.36	CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B01ZYH	(1S,2R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-1-methyl-cyclopentanol	Investigative	44292887	C19H20F3NO4S	415.4	C[C@@]1(CCC[C@H]1OC2=C(C=C(C=N2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B02KMC	4-(4-Chloro-3-methylphenyl)-1,2-difluoro-5-[4-(methylsulfonyl)phenyl]benzene	Investigative	10572620	C20H15ClF2O2S	392.8	CC1=C(C=CC(=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B02SYO	(Z)-4-Amino-4-(5-chlorofuran-2-yl)-3-phenylbut-3-en-2-one	Investigative	71682135	C14H12ClNO2	261.7	CC(=O)/C(=C(/C1=CC=C(O1)Cl)\\N)/C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B07JIE	1-[4,4-Di(fluoromethyl)-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene	Investigative	10339727	C20H19F3O2S	380.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC(C2)(CF)CF)C3=CC=C(C=C3)F	IC50 = 58000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B08BNX	2-(Trifluoromethyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	10157862	C17H11F4NO2S2	401.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B08WRE	3-Amino-N-[3-(trifluoromethyl)phenyl]benzamide	Investigative	2317371	C14H11F3N2O	280.24	C1=CC(=CC(=C1)N)C(=O)NC2=CC=CC(=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B09SVN	3-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	20115449	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(F)(F)F)NC(=O)C2=CC(=CC=C2)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0C1YK	3-(3,5-Dimethoxyphenyl)-7-hydroxy-2H-1-benzopyran-2-one	Investigative	44406313	C17H14O5	298.29	COC1=CC(=CC(=C1)C2=CC3=C(C=C(C=C3)O)OC2=O)OC	IC50 = 105000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0DIA9	(2S)-6-Bromo-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	118720946; 118753648	C13H10BrF3O3	357.15	[2H]C([2H])([2H])C1=CC2=C(C=C([C@H](O2)C(F)(F)F)C(=O)O)C(=C1Br)C([2H])([2H])[2H]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0EOV6	6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole	Investigative	15388846	C18H13FN2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C=CS3)C4=CC=C(C=C4)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0H6QK	4-[3-(4-Methoxyphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732341	C23H21N3O4S	435.5	COC1=CC=C(C=C1)C2C3COC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 78100 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0HX8R	2-(6-Chloro-9H-carbazol-2-yl)-propionic acid 2-nitrooxy-ethyl ester	Investigative	44587411	C17H15ClN2O5	362.8	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)OCCO[N+](=O)[O-]	IC50 = 110000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0IFK5	(E)-N-Butyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71495784	C24H29NO4	395.5	CCCCNC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0JP2B	4-[(4-Trifluoromethyl-benzylidene)-amino]-benzenesulfonamide	Investigative	404325	C14H11F3N2O2S	328.31	C1=CC(=CC=C1C=NC2=CC=C(C=C2)S(=O)(=O)N)C(F)(F)F	IC50 = 182190 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0M2BU	4-[2-(3,4,5-Trifluorophenyl)-1-cyclopentenyl]benzenesulfonamide	Investigative	10570051	C17H14F3NO2S	353.4	C1CC(=C(C1)C2=CC(=C(C(=C2)F)F)F)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0MZ2Q	2-(Cyclohexylmethoxy)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine	Investigative	45272015	C19H21F3N2O3S	414.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)OCC3CCCCC3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0NK4F	4-(4-(Methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	23497471	C12H10F3N3O2S	317.29	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0OT4L	2-(2-Oxochromen-7-yl)oxyethyl 5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137649486	C28H23N3O7S	545.6	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC5=C(C=C4)C=CC(=O)O5	IC50 ~ 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0OTC8	3-(3-Fluoro-4-methoxy-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophene	Investigative	44330646	C18H15FO3S2	362.4	COC1=C(C=C(C=C1)C2=CSC=C2C3=CC=C(C=C3)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0PK3Z	Chembl4173747	Investigative	138542656	C30H36N2O11	600.6	COC1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(C=C3)OC)CC(=O)NCCCCC(=O)OC[C@@H]4[C@@H]([C@@H]([C@H](C(O4)O)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0QM7J	6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole	Investigative	10385715	C18H12F2N2O2S2	390.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C=CS3)C4=CC(=C(C=C4)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0QP8H	1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)pyrrole	Investigative	10829132	C17H14FNO2S	315.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CN2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0R7NV	3-[[4-(4-Methoxyphenyl)piperazin-1-yl]methyl]-6,6-dimethyl-4-phenyl-4,5-dihydrooxazine	Investigative	122182705	C24H31N3O2	393.5	CC1(CC(C(=NO1)CN2CCN(CC2)C3=CC=C(C=C3)OC)C4=CC=CC=C4)C	IC50 = 50600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0S3YR	2-(Cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxamide	Investigative	45272818	C18H22N4O3S	374.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCCCC3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0TJ4F	N-(Methylsulfonyl)-N-(3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)-phenyl)methanesulfonamide	Investigative	49805305	C20H26N2O6S2	454.6	CS(=O)(=O)N(C1=CC(=CC=C1)OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0UJI7	4,6-Dimethyl-2-[3-oxo-3-(4-phenylpiperazin-1-yl)propyl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134134738	C21H24N4O2S	396.5	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCN(CC3)C4=CC=CC=C4)C	IC50 = 169824.37 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0VL3J	2-[3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propan-2-ol	Investigative	44383610	C20H19FO3S2	390.5	CC(C)(C1=C(C(=CS1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0Y9DM	1-(2-(4-(2-Nitrophenoxy)-phenoxy)ethyl)pyrrolidine	Investigative	49804917	C18H20N2O4	328.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3[N+](=O)[O-]	IC50 = 61000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B0Z1RI	4-[8-Fluoro-7-methoxy-4-oxo-3-(trifluoromethyl)-5H-isothiochromeno[4,3-c]pyrazol-1-yl]benzenesulfonamide	Investigative	44327837	C18H13F4N3O4S2	475.4	COC1=C(C=C2C(=C1)CS(=O)C3=C2N(N=C3C(F)(F)F)C4=CC=C(C=C4)S(=O)(=O)N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B13IEP	Benzenesulfonamide,4-(4-cyclohexyl-2-methyl-5-oxazolyl)-n-methyl-	Investigative	15871001	C17H22N2O3S	334.4	CC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)NC)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B14FJB	3-Mesityl-4-phenyl-5-methylisoxazole	Investigative	11231244	C19H19NO	277.4	CC1=CC(=C(C(=C1)C)C2=NOC(=C2C3=CC=CC=C3)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B14LHY	4-[3-(2-Chloro-6-fluorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732348	C22H17ClFN3O3S	457.9	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=C(C=CC=C5Cl)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B15PUK	4-((4-(Dimethylamino)benzylidene)amino)benzenesulfonamide	Investigative	308411	C15H17N3O2S	303.4	CN(C)C1=CC=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 195740 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B16IUG	3-(3-Fluorophenyl)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one	Investigative	9906892	C19H17FO4S	360.4	CC1(C(=C(C(=O)O1)C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 70000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B17GID	4-[3-(2-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548447	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B17LIW	4-[5-Tert-butyl-3-(2-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548633	C20H21FN2O2	340.4	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2F)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B17WKM	3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile	Investigative	10109361	C16H10F2N2O2S2	364.4	CS(=O)(=O)C1=CC2=C(C=C1)C(=C(N2)C#N)SC3=C(C=C(C=C3)F)F	IC50 ~ 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B18AOS	2-(4-(Methylsulfonyl)phenyl)-3-phenylthiazolidin-4-one	Investigative	10359484	C16H15NO3S2	333.4	CS(=O)(=O)C1=CC=C(C=C1)C2N(C(=O)CS2)C3=CC=CC=C3	IC50 = 96100 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B19RNG	1-(3-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile	Investigative	71714209	C19H15FN2O2S	354.4	CC1=C(C=C(N1C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C#N	IC50 = 50500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B19ZWB	3-(3-Fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	21472746	C18H15FO5S	362.4	CC1(C(=C(C(=O)O1)C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1B7NM	4-[2-(4-Trifluoromethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide	Investigative	44395090	C19H13F3N4O3S	434.4	C1=CC2=C(C(=NN2N=C1)C3=CC=C(C=C3)OC(F)(F)F)C4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1BCO8	4-(2-(4-Fluorophenyl)-1H-pyrrol-1-yl)-N-methylbenzenesulfonamide	Investigative	10520447	C17H15FN2O2S	330.4	CNS(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1E4YZ	3-(1,3-Benzodioxol-5-yl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706109	C18H15F3N2O4S	412.4	CS(=O)(=O)C1=CC=C(C=C1)N2C(CC(=N2)C(F)(F)F)C3=CC4=C(C=C3)OCO4	IC50 = 57530 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1ESG9	3-[(4-Chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10504537	C25H21ClFNO3S	470	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)COC4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1F2RA	1-(3,4-Dimethoxyphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene	Investigative	10668927	C21H18F2O4S	404.4	COC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1G6LQ	1-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-3-nitrooxymethyl-1H-pyrazole	Investigative	9969968	C17H21N3O5S	379.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NN2C3CCCCC3)CO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1HNB6	1-[1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]ethanone	Investigative	10523255	C20H18FNO3S	371.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1I9HL	2-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}ethyl Nitrate	Investigative	16125488	C18H15ClFN3O6S	455.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCO[N+](=O)[O-])F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1ILA7	4-Thiazolidinone, 3,3'-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-	Investigative	2826057	C22H24N2O4S2	444.6	COC1=CC=C(C=C1)C2N(C(=O)CS2)CCN3C(SCC3=O)C4=CC=C(C=C4)OC	IC50 = 53700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1JL3E	2-(4-Chlorophenyl)-4-(methylsulfonylmethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10670044	C18H17ClN2O4S2	424.9	CS(=O)(=O)CC1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1L9XT	3,5-Diphenyl-1,2-oxazole-4-carboxylic acid	Investigative	13804275	C16H11NO3	265.26	C1=CC=C(C=C1)C2=C(C(=NO2)C3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1MQP4	2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10200861	C18H14F4N2O2S	398.4	CC1=CC(=CC(=C1)F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1QN3X	6-[4-(Methylsulfonyl)phenyl]-5-[4-(trifluoromethyl)phenyl]spiro[2.4]hept-5-ene	Investigative	10620528	C21H19F3O2S	392.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1QU6D	2-(3,5-Difluoro-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10741367	C18H13F5N2O3S	432.4	COC1=C(C=C(C=C1F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1TKH3	4-[(3E,6E,9E,12E)-Pentadeca-3,6,9,12-tetraenyl]sulfanylbutanoic acid	Investigative	44584307	C19H30O2S	322.5	CC/C=C/C/C=C/C/C=C/C/C=C/CCSCCCC(=O)O	IC50 = 81000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1UX9G	(E)-N-Butan-2-yl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71495989	C24H29NO4	395.5	CCC(C)NC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1W5SP	4-[5-Tert-butyl-3-(3-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68308827	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1WR0D	N-(4-Bromophenylsulfonyl)Picolinamide	Investigative	57401639	C12H9BrN2O3S	341.18	C1=CC=NC(=C1)C(=O)NS(=O)(=O)C2=CC=C(C=C2)Br	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1XMA7	2-Bromo-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene	Investigative	44330429	C17H12BrFO2S2	411.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2C3=CC=C(C=C3)F)Br	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B1Z2XK	N,N-Dimethyl-4-[1-(4-methylsulfonylphenyl)triazol-4-yl]aniline	Investigative	44581929	C17H18N4O2S	342.4	CN(C)C1=CC=C(C=C1)C2=CN(N=N2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B20DTU	2-Phenyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)thiazole	Investigative	15485017	C22H16FNO2S2	409.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=N2)C3=CC=CC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B20WNK	N-[6-(4,5-Dimethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286564	C15H16N2O3S3	368.5	CC1=C(SC(=N1)SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B21IWQ	4-(4-Difluoromethyl-2-pyridin-3-yl-imidazol-1-yl)-benzenesulfonamide	Investigative	10569839	C15H12F2N4O2S	350.3	C1=CC(=CN=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B25SPV	4-[(3,4,5-Trimethoxybenzylidene)amino]benzenesulfonamide	Investigative	404319	C16H18N2O5S	350.4	COC1=CC(=CC(=C1OC)OC)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 167090 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B26WTR	4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-benzenesulfonamide	Investigative	11002614	C17H22N2O4S	350.4	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)OC)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B27KEJ	2-[4-(2-Fluorophenyl)piperazin-1-ylmethyl]-4,6-dimethylisothiazolo[5,4-b]pyridin-3(2H)-one	Investigative	11717695	C19H21FN4OS	372.5	CC1=CC(=NC2=C1C(=O)N(S2)CN3CCN(CC3)C4=CC=CC=C4F)C	IC50 = 141253.75 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B28FJT	Methyl 5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	10738225	C17H14FN3O4S	375.4	COC(=O)C1=NN(C(=C1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B29BFS	2-Tert-butoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine	Investigative	45271997	C16H17F3N2O3S	374.4	CC(C)(C)OC1=NC(=CC(=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 = 52000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B29YUW	N-Butyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45270348	C16H18F3N3O2S	373.4	CCCCNC1=NC(=CC(=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 96150 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2B9TF	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-hydroxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	136094859	C26H18ClN5O6S	564	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC=C(C=C4)O)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2BC7E	3-[4-Methyl-1-(4-methylsulfonylphenyl)imidazol-2-yl]pyridine	Investigative	10663006	C16H15N3O2S	313.4	CC1=CN(C(=N1)C2=CN=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2EO1U	(4S,4Ar,8aR)-3-(carbazol-9-ylmethyl)-4-(4-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-4H-1,2-benzoxazine	Investigative	122182712	C28H28N2O2	424.5	COC1=CC=C(C=C1)[C@@H]2[C@H]3CCCC[C@H]3ON=C2CN4C5=CC=CC=C5C6=CC=CC=C64	IC50 = 50800 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2G5SZ	N-(2-(1-(4-Bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl)-4-chlorobenzamide	Investigative	9871042	C26H24BrClN2O2	511.8	CC1=C(C2=C(N1CC3=CC=C(C=C3)Br)C=CC(=C2)OC)CCNC(=O)C4=CC=C(C=C4)Cl	IC50 ~ 66000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2I5RH	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1-phenethyl-5-trifluoromethyl-1H-pyrazole	Investigative	9957131	C25H20F4N2O2S	488.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C(=C2C3=CC=C(C=C3)F)C(F)(F)F)CCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2IEA9	(R)-8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	11552163	C14H10F6O4	356.22	CCC1=CC(=CC2=C1O[C@H](C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2IO8D	3-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline	Investigative	49805302	C18H22N2O2	298.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2K0JR	4-[(4-Sulfamoyl-phenylimino)-methyl]-benzoic acid methyl ester	Investigative	404376	C15H14N2O4S	318.3	COC(=O)C1=CC=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 183500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2K1DI	8-(4-Carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53316515	C18H10ClF3O5	398.7	C1=CC(=CC=C1C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2KC9I	2-Methyl-4-cycloheptyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	15429222	C18H23NO3S	333.4	CC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3CCCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2LIF8	N-[6-(2-Fluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	10569949	C16H14FNO3S2	351.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=CC=CC=C3F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2LX8R	4-Chloro-5-(2-fluorophenyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10882658	C16H12ClFN2O2S	350.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC=CC=C3F)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2M7LF	1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrrole	Investigative	10809969	C18H13F4NO2S	383.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(N2C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2ND0Z	4-[3-(4-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732330	C23H20FN3O2S	421.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=C(C=C4)F)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2PUG6	6-Chloro-7-((2,6-dimethylpiperidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53319287	C19H21ClF3NO3	403.8	CC1CCCC(N1CC2=C(C=C3C=C(C(OC3=C2)C(F)(F)F)C(=O)O)Cl)C	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2QFK8	4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-phenylsulfanyl-5H-furan-2-one	Investigative	10199429	C19H18O4S2	374.5	CC1(C(=C(C(=O)O1)SC2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2QNL6	6-Chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	11464135	C19H14ClF3O3S	414.8	CCSC1=CC=C(C=C1)C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl	IC50 = 75900 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2SOY1	4-[5-(3-Chloro-4-methylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10765111	C17H14ClF3N4O2S	430.8	CNC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)Cl	IC50 = 77700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2UI8R	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole	Investigative	15380227	C16H13FN2O2S	316.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=NN2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2W4ZE	2-(3,5-Dibromo-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10506935	C18H13Br2F3N2O3S	554.2	COC1=C(C=C(C=C1Br)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2XQW4	2-(1-Hydroxycyclopentylmethoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine	Investigative	15887862	C19H20F3NO4S	415.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)C(F)(F)F)OCC3(CCCC3)O	IC50 = 83000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2XTY7	2-[[2-Amino-2-[1-(3-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]acetyl]amino]ethyl nitrate	Investigative	73333200	C22H23FN4O6S	490.5	CC1=C(C=C(N1C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(C(=O)NCCO[N+](=O)[O-])N	IC50 = 140000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2YMN1	3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran	Investigative	44316046	C21H15FO3S	366.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C3=CC=CC=C3O2)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B2ZI5J	2-(4-Chlorophenyl)-4-(methoxymethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	11793963	C18H17ClN2O3S	376.9	COCC1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B30LDC	4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-2-methyl-oxazole	Investigative	10642954	C15H12F3N3O3S	371.3	CC1=NC(=CO1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B30MNV	4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-(pyridin-4-yloxy)-5H-furan-2-one	Investigative	15461526	C18H17NO5S	359.4	CC1(C(=C(C(=O)O1)OC2=CC=NC=C2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B30OHU	5-[4,5-Difluoro-2-[4-(methylsulfonyl)phenyl]phenyl]-1,3-benzodioxole	Investigative	10500466	C20H14F2O4S	388.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC4=C(C=C3)OCO4)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B32OYQ	N-[(E)-[3-(4-Bromophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]amino]-2-(2,4-dichlorophenoxy)acetamide	Investigative	137661666	C17H12BrCl2N3O3S	489.2	C1C(=O)N(/C(=N\\NC(=O)COC2=C(C=C(C=C2)Cl)Cl)/S1)C3=CC=C(C=C3)Br	IC50 = 134780 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B34YCU	3-(3-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	9928728	C19H15FO4S	358.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC(=CC=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B38KHF	5-Chloro-3-(4-methanesulfonyl-phenyl)-4''-methyl-[2,3'']bipyridinyl	Investigative	10109075	C18H15ClN2O2S	358.8	CC1=C(C=NC=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B39LXM	5-((1R,4Ar,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-pentanoic acid	Investigative	9906813	C24H38O2	358.6	C[C@]1(CCC[C@@]2(C1CCC3C2=CC[C@](C3)(C)C=C)C)CCCCC(=O)O	IC50 = 52600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3AR2U	6-(3,4-Difluorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene	Investigative	10594681	C20H18F2O2S	360.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CC3)C4=CC(=C(C=C4)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3B6XW	4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10156048	C16H16F3N3O2S	371.4	C1CCC(=CC1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3CLD7	4-[5-(4-Hydroxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	135532444	C16H12F3N3O3S	383.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3CXD5	4-Amino-N-[3-(trifluoromethyl)phenyl]benzamide	Investigative	2756535	C14H11F3N2O	280.24	C1=CC(=CC(=C1)NC(=O)C2=CC=C(C=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3DAY0	6,8-Bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	71509612	C13H11F3O3	278.26	[2H]C([2H])([2H])C1=CC(=C2C(=C1)C=C(C(O2)C(F)(F)F)C(=O)O)C([2H])([2H])[2H]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3EUD2	2-Methyl-4-(4-fluorophenyl)-5-[4-(ethylsulfonyl)phenyl]oxazole	Investigative	44374212	C18H16FNO3S	345.4	CCS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(O2)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3GLW1	2-Methyl-3-(4-fluorobenzyl)-6-(methylsulfonyl)-1H-indole	Investigative	11404334	C17H16FNO2S	317.4	CC1=C(C2=C(N1)C=C(C=C2)S(=O)(=O)C)CC3=CC=C(C=C3)F	IC50 = 63900 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3GYX9	4-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzenemethanol	Investigative	10426661	C19H20O3S	328.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)CO	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3H6NO	4-(5-Tert-butyl-3-phenyl-3,4-dihydropyrazol-2-yl)benzoic acid	Investigative	68292820	C20H22N2O2	322.4	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3IJT5	2-[4-[5-Chloro-3-(4-sulfamoylphenyl)imidazol-4-yl]-2-fluorophenoxy]ethyl nitrate	Investigative	16125423	C17H14ClFN4O6S	456.8	C1=CC(=CC=C1N2C=NC(=C2C3=CC(=C(C=C3)OCCO[N+](=O)[O-])F)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3JNB9	4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-benzenesulfonamide	Investigative	11056746	C17H22N2O3S	334.4	CC1=C(C=CC(=C1)C2=C(N=C(O2)C)C3CCCCC3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3LT5J	4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805050	C17H20N2O2	284.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3MEY9	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine	Investigative	49805055	C16H19N3O2	285.34	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=NC=CN=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3NCX5	5-Amino-N-[4-(trifluoromethyl)phenyl]pyridine-2-carboxamide	Investigative	24854032	C13H10F3N3O	281.23	C1=CC(=CC=C1C(F)(F)F)NC(=O)C2=NC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3OWK1	N-Cyclohexyl-4-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine	Investigative	45272817	C17H21N3O2S	331.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=NC=C2)NC3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3QN4W	(7-Tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-(4,5-dihydro-pyrazol-1-yl)-amine	Investigative	44344893	C17H25N3O	287.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)NN3CCC=N3)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3RMB4	N-Benzyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	9931215	C19H16F3N3O2S	407.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NCC3=CC=CC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3SK0V	2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-4-phenyl-1H-imidazole	Investigative	10294921	C22H17ClN2O2S	408.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3SNU5	4-[(4-Hydroxyphenyl)iminomethyl]benzenesulfonamide	Investigative	44456631	C13H12N2O3S	276.31	C1=CC(=CC=C1C=NC2=CC=C(C=C2)O)S(=O)(=O)N	IC50 = 51830 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3STY4	5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-thiophen-3-yl-5H-furan-2-one	Investigative	44272274	C16H14O5S2	350.4	CC1(C(=C(C(=O)O1)C2=CSC=C2)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3U0YM	6-Cyano-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid	Investigative	21883613	C12H6F3NO3	269.18	C1=CC2=C(C=C1C#N)C=C(C(O2)C(F)(F)F)C(=O)O	IC50 = 115000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3U7YL	3-(3,4-Dichloro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one	Investigative	11154503	C19H14Cl2O5S	425.3	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3UE8I	3-[[1-(4-Bromophenyl)triazol-4-yl]methyl]-5-methyl-1,3-benzoxazol-2-one	Investigative	76320831	C17H13BrN4O2	385.2	CC1=CC2=C(C=C1)OC(=O)N2CC3=CN(N=N3)C4=CC=C(C=C4)Br	IC50 = 188200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3V2FS	6-(4-Methanesulfonyl-phenyl)-3-methyl-5-phenyl-imidazo[2,1-b]thiazole	Investigative	44365570	C19H16N2O2S2	368.5	CC1=CSC2=NC(=C(N12)C3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3VYE2	1-Chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene	Investigative	9927594	C18H17ClO2S	332.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3XC0M	2-[[1-(4-Ethoxyphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643684	C18H16N4O2S	352.4	CCOC1=CC=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 163240 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3XO5J	(2R,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-[4-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenoxy]oxane-2-carboxylic acid	Investigative	71716000	C23H22O11S	506.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=C(C=C3)O[C@H]4[C@H]([C@H]([C@@H]([C@@H](O4)C(=O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3Y1WO	6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	44395024	C21H18FN3O2S	395.5	CCC1=NN2C(=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)S(=O)(=O)C)C=C1	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B3Z2MD	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-phenylphenyl]propanoate	Investigative	56665210	C21H21NaO3	344.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=CC=C3)C(=O)[O-].[Na+]	IC50 = 54000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B40SUR	(S)-6-Chloro-7-isobutyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53325873	C15H14ClF3O3	334.72	CC(C)CC1=C(C=C2C=C([C@H](OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B41UVQ	5-(4-Methanesulfonyl-phenyl)-2,3-dimethyl-6-phenyl-imidazo[2,1-b]thiazole	Investigative	22148957	C20H18N2O2S2	382.5	CC1=C(SC2=NC(=C(N12)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B41WAJ	N-Cyclohexyl-5-methyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	10273161	C19H22F3N3O2S	413.5	CC1=C(N=C(N=C1C(F)(F)F)NC2CCCCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B42CWZ	{2-Chloro-4-[1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-methyl-amine	Investigative	10598702	C18H15ClF3N3O2S	429.8	CNC1=C(C=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B42DXU	3,3-Dimethyl-5-[pyrrolizino(imino)methyl]-7-tert-butyl-2,3-dihydrobenzofuran	Investigative	10637982	C19H28N2O	300.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)C(=N)N3CCCC3)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B43KXS	2-(3,5-Dichlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10741533	C17H11Cl2F3N2O2S	435.2	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B43SPG	Clematichinenoside C	Investigative	49799271	C70H114O34	1499.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B45HNP	US9271961, Bmt 4-90	Investigative	124222779	C14H12N2O5	288.25	COC1=CC(=C(C=C1)[N+](=O)[O-])NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B45WGA	2-(3-Methylsulfanylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10764155	C18H15F3N2O2S2	412.5	CSC1=CC=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B48OAC	1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-pyrazole	Investigative	10472597	C17H12F3N5	343.31	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)N=[N+]=[N-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B49AWL	1-(3,5-Difluorophenyl)-2-[4-(methylsulfonyl)phenyl]cyclopentene-5-one	Investigative	9798392	C18H14F2O3S	348.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)C3=CC(=CC(=C3)F)F	IC50 = 61000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B49RWU	5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester	Investigative	44365758	C21H18N2O4S2	426.5	CCOC(=O)C1=CSC2=NC(=C(N12)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B49SBI	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051124	C26H17ClFN5O5S	566	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC(=CC=C4)F)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 = 74300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4A8KI	4-(3-Methoxy-5-phenyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10853804	C16H15N3O3S	329.4	COC1=NN(C(=C1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4ASO1	4-(4-(Methylsulfonyl)phenyl)-N-((tetrahydro-2H-pyran-4-yl)methyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45267710	C18H20F3N3O3S	415.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NCC3CCOCC3)C(F)(F)F	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4BLU5	2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propan-2-ol	Investigative	44383560	C20H19FO3S2	390.5	CC(C)(C1=C(C(=CS1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4DU6X	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(2-ethylpiperidin-1-yl)prop-2-en-1-one	Investigative	71652532	C27H33NO4	435.6	CCC1CCCCN1C(=O)/C=C/C2=C(C=C(C=C2OC)OC)/C=C/C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4E2KY	N-[6-(5-Methyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286434	C14H14N2O3S3	354.5	CC1=CN=C(S1)SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4EF3O	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dihexylprop-2-enamide	Investigative	71652367	C32H45NO4	507.7	CCCCCCN(CCCCCC)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4EW3S	N-Methyl-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805307	C20H26N2O4S	390.5	CN(C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4FC8U	6-Chloro-7-((isopropyl(methyl)amino)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53325872	C16H17ClF3NO3	363.76	CC(C)N(C)CC1=C(C=C2C=C(C(OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4GB5P	4-{4-Chloro-5-[3-fluoro-4-(2-hydroxyethoxy)phenyl]-1H-imidazol-1-yl}benzenesulfonamide	Investigative	16125421	C17H15ClFN3O4S	411.8	C1=CC(=CC=C1N2C=NC(=C2C3=CC(=C(C=C3)OCCO)F)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4GJA0	4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(phenylthio)pyrimidine	Investigative	45269475	C23H17FN2O2S2	436.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)SC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4GW6Y	4-(4-Hydroxybenzylideneamino)benzenesulfonamide	Investigative	404202	C13H12N2O3S	276.31	C1=CC(=CC=C1C=NC2=CC=C(C=C2)S(=O)(=O)N)O	IC50 = 148200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4HB0K	4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N,N-dimethyl-benzenesulfonamide	Investigative	10688810	C18H17FN2O2S	344.4	CN(C)S(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4K9MD	N-(3-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide	Investigative	24853947	C13H10F3N3O	281.23	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=C(C=CC=N2)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4LJ5T	4-[5-(3,4-Dimethoxyphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10202758	C18H16F3N3O4S	427.4	COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4MCR6	3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272086	C18H14Cl2O5S	413.3	CC1(C(=C(C(=O)O1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 = 75000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4N1UE	1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole	Investigative	44307569	C19H17FN2O2S	356.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C=C2C3=CC=C(C=C3)F)CC=C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4OFC8	N-(4-Amino-2-pyridyl)-4-(trifluoromethyl)benzamide	Investigative	24854030	C13H10F3N3O	281.23	C1=CC(=CC=C1C(=O)NC2=NC=CC(=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4P3RG	2-(4-Pyridinyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912123	C21H15FN2O2S2	410.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=NC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4R7LQ	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dimethylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051923	C28H22ClN5O5S	576	CC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4S0BL	1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-4-cyclopropyl-butan-1-one	Investigative	10830016	C22H30O2	326.5	CC1(COC2=C(C=C(C=C21)C(=O)CCCC3CC3)C4CCCC4)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4SPG3	4-[2-Methyl-5-(4-bromophenyl)-4-thiazolyl]benzenesulfonamide	Investigative	44271257	C16H13BrN2O2S2	409.3	CC1=NC(=C(S1)C2=CC=C(C=C2)Br)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 115000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4SRD9	Furan L	Investigative	24871714	C17H22O3	274.35	CCCCCCC1=CC=C(O1)C2=CC(=C(C=C2)O)OC	IC50 = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4TGY8	1-(4-Methanesulfonylphenyl)-3-[(3,4-dimethoxy)phenoxymethyl]-5-phenyl-1H-pyrazole	Investigative	11374699	C25H24N2O5S	464.5	COC1=C(C=C(C=C1)OCC2=NN(C(=C2)C3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)C)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4TXG6	3-[4-(Trifluoromethyl)phenyl]-4-(4-sulfamoylphenyl)-4-oxazoline-2-one	Investigative	10643725	C16H11F3N2O4S	384.3	C1=CC(=CC=C1C2=COC(=O)N2C3=CC=C(C=C3)C(F)(F)F)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4UEA9	6-[4-(Methylsulfonyl)phenyl]-5-[3-fluoro-4-methoxyphenyl]spiro[2.4]hept-5-ene	Investigative	10571335	C21H21FO3S	372.5	COC1=C(C=C(C=C1)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4V8LP	5-Cycloheptylidenemethyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole	Investigative	10221647	C22H24O4S	384.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2C=C4CCCCCC4)OCO3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4VQ0G	(2S)-6-Chloro-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	118720945	C13H10ClF3O3	312.7	[2H]C([2H])([2H])C1=CC2=C(C=C([C@H](O2)C(F)(F)F)C(=O)O)C(=C1Cl)C([2H])([2H])[2H]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4WR2B	2-Hydroxy-5-[(4-sulfamoyl-phenylimino)-methyl]-benzoic acid	Investigative	405491	C14H12N2O5S	320.32	C1=CC(=CC=C1N=CC2=CC(=C(C=C2)O)C(=O)O)S(=O)(=O)N	IC50 = 85130 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4X1EZ	4-[2-(3,5-Dichloro-4-methoxyphenyl)-4,5-difluorophenyl]benzenesulfonamide	Investigative	11797537	C19H13Cl2F2NO3S	444.3	COC1=C(C=C(C=C1Cl)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)N)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4X1JT	2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)oxazole	Investigative	18701559	C17H14FNO3S	331.4	CC1=NC(=C(O1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4YZF8	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-trifluoromethoxy-phenoxy)-pyran-4-one	Investigative	11396529	C20H15F3O6S	440.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B4ZBX9	3-Morpholin-4-ylpropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate	Investigative	57780770	C21H21ClN2O5	416.9	C1COCCN1CCCOC(=O)C2=C(C(=NO2)C3=CC=C(O3)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B52OCV	Chembl4127794	Investigative	145963415	C16H15N3O3	297.31	C/C(=N\\N=C/1\\CCC(=O)N1C)/C2=CC3=CC=CC=C3OC2=O	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B53FJE	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-spiro[4.5]dec-2-ene	Investigative	10810080	C23H25FO2S	384.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CCCCC3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B53XGV	4-[3-(3-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732333	C23H20BrN3O2S	482.4	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC(=CC=C4)Br)C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 100200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B54FDW	Sodium;acetyl-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylazanide	Investigative	23717031	C18H15N2NaO4S	378.4	CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)[N-]C(=O)C.[Na+]	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B57GXV	2-(4-Methylphenyl)sulfonyl-3-naphthalen-1-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706118	C21H17F3N2O2S	418.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=CC=CC4=CC=CC=C43	IC50 = 152600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B59PIQ	4-[3-(2-Chlorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732331	C23H20ClN3O2S	437.9	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=CC=C4Cl)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5A9IW	Chembl4169347	Investigative	131801158	C20H16ClNO4S	401.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2C(=O)CCC3)C(=O)C4=CC=C(C=C4)Cl	IC50 = 104000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5AQ3F	1,2-Difluoro-4-(4-methoxy-3-methylphenyl)-5-(4-methylsulfonylphenyl)benzene	Investigative	10739009	C21H18F2O3S	388.4	CC1=C(C=CC(=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5ATN6	8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-trifluoromethyl-1,5-dihydro-isothiochromeno[4,3-c]pyrazole	Investigative	44327824	C19H14F4N2O3S2	458.5	COC1=C(C=C2C(=C1)CSC3=C2N(N=C3C(F)(F)F)C4=CC=C(C=C4)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5BD6U	1-[2-(4-Methylsulfonylphenyl)-1-cyclopentenyl]-4-trifluoromethylbenzene	Investigative	9947309	C19H17F3O2S	366.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5BUN2	Ethyl 2-[4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrazol-1-yl]acetate	Investigative	10227082	C21H18F4N2O4S	470.4	CCOC(=O)CN1C(=C(C(=N1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5DQG7	4-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]butanoic acid	Investigative	134141655	C12H14N2O3S	266.32	CC1=CC(=NC2=C1C(=NS2)OCCCC(=O)O)C	IC50 = 181970.09 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5DR6I	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-phenoxy-pyran-4-one	Investigative	11279733	C19H16O5S	356.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5FC1B	Unii-3G75T52B7D	Investigative	44266451	C18H13ClN2O4S	388.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CN=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5FCO7	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-m-tolyloxy-pyran-4-one	Investigative	10292572	C20H18O5S	370.4	CC1=CC(=CC=C1)OC2=C(OC(=CC2=O)C)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5FX1D	4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide	Investigative	2950007	C22H21N3O3S	407.5	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5G4CO	N-(2-Aminophenyl)-4-(trifluoromethyl)benzamide	Investigative	572427	C14H11F3N2O	280.24	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)C(F)(F)F	IC50 = 88000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5G9HE	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051109	C26H17Cl2N5O5S	582.4	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC=CC=C4Cl)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 = 86240 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5H7JY	5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-imidazo[2,1-b]thiazole	Investigative	10316962	C19H16N2O2S2	368.5	CC1=CN2C(=C(N=C2S1)C3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5LM3K	3-(4-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	9841715	C19H15FO4S	358.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5MJ8Q	4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68292588	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5N2DF	3-(4-Bromophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	11419147	C19H15BrO5S	435.3	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)Br	IC50 = 119000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5NHK0	2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(5-chloro-2-thienyl)oxazole	Investigative	15429226	C15H12ClNO3S2	353.8	CC1=NC(=C(O1)C2=CC=C(S2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 93000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5QK7R	4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-imidazole	Investigative	17828963	C16H13FN2O2S	316.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(NC=N2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5R3WM	2-(2-Hydroxy-2-methylpropoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine	Investigative	15887860	C17H18F3NO4S	389.4	CC(C)(COC1=C(C=C(C=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5SR3T	Chembl4127948	Investigative	145962585	C17H17N3O2	295.34	CC1=CC/C(=N/N=C(\\C)/C2=CC3=CC=CC=C3OC2=O)/N1C	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5SX3M	5-Methyl-4-phenyl-3-(2,4,6-trimethoxy-phenyl)-isoxazole	Investigative	11301795	C19H19NO4	325.4	CC1=C(C(=NO1)C2=C(C=C(C=C2OC)OC)OC)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5SYI4	[3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indol-2-yl]-methanol	Investigative	22034361	C16H14FNO3S2	351.4	CS(=O)(=O)C1=CC2=C(C=C1)C(=C(N2)CO)SC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5ULG6	5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272272	C21H22O5S	386.5	CC(C)C1=CC=C(C=C1)C2=C(C(OC2=O)(C)O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5VA1J	6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371399	C18H14FN3O2S2	387.5	CC1=NN2C(=C(SC2=N1)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC(=CC=C4)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5VNE2	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(2-methylpropyl)prop-2-enamide	Investigative	71652200	C24H29NO4	395.5	CC(C)CNC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5WKF8	2-Phenyl-3-[4-(methylsulfonyl)phenyl]imidazo[2,1-b]benzothiazole	Investigative	44365764	C22H16N2O2S2	404.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C4=CC=CC=C4S3)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5Y3TI	[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S,6S)-4-[(2S,3R,4S,5R)-5-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate	Investigative	49799273	C76H124O40	1677.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B5Z9BX	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051121	C26H17Cl2N5O5S	582.4	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC(=CC=C4)Cl)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B60SWZ	N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-3,4-dihydro-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	46880352	C21H16Cl2N2O4S	463.3	C1=CC=C2C(=C1)C(C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B61QSU	Chembl4129984	Investigative	145963101	C21H23N3O4	381.4	CCN\\1C(=C(C/C1=N/N=C(\\C)/C2=CC3=CC=CC=C3OC2=O)C(=O)OCC)C	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B63KRB	4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidin-4-ol	Investigative	44346053	C25H29FN4O2	436.5	C1CCC(CC1)NC2=NC=CC(=C2)C3=C(N=C(O3)C4(CCNCC4)O)C5=CC=C(C=C5)F	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B64JNE	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-bicyclo[2.2.1]hept-2-ene	Investigative	44383162	C20H19FO2S	342.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C3CCC2C3)C4=CC=C(C=C4)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B64JTA	4-[3-(3-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548631	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B67OPD	(2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thiazolidine-4-carboxamide	Investigative	50908401	C20H20N4OS	364.5	CC1=CC=C(C=C1)C2=NN(C=C2C3N[C@@H](CS3)C(=O)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B67VZI	N-(4-Methylphenyl)sulfonylpyridine-3-carboxamide	Investigative	1500232	C13H12N2O3S	276.31	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6AC2I	1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile	Investigative	11792433	C19H15FN2O2S	354.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6BPC0	N-(6-Cyclohexylsulfanyl-1-oxo-indan-5-yl)-methanesulfonamide	Investigative	10807025	C16H21NO3S2	339.5	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3CCCCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6CZ9K	N-(4-Fluorophenyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45267770	C18H13F4N3O2S	411.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 65800 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6DIK4	(5R)-3-Isopropoxy-4-[4-(methylsulfonyl)phenyl]-5beta-ethyl-5-methyl-2,5-dihydrofuran-2-one	Investigative	10088506	C17H22O5S	338.4	CC[C@@]1(C(=C(C(=O)O1)OC(C)C)C2=CC=C(C=C2)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6DQC2	Phenylmethyl 2-{4-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate	Investigative	11853318	C26H21Cl2NO4	482.4	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2Cl)OC)CC(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6EHI5	N-Cyclohexyl-5-methyl-4-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine	Investigative	45267717	C18H23N3O2S	345.5	CC1=CN=C(N=C1C2=CC=C(C=C2)S(=O)(=O)C)NC3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6FNR4	4-(6-Benzyl-benzo[1,3]dioxol-5-yl)-benzenesulfonamide	Investigative	11337592	C20H17NO4S	367.4	C1OC2=C(O1)C=C(C(=C2)CC3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)N	IC50 = 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6G4AH	6-[4-(Methylsulfonyl)phenyl]-5-[3-bromo-4-methoxyphenyl]spiro[2.4]hept-5-ene	Investigative	10812673	C21H21BrO3S	433.4	COC1=C(C=C(C=C1)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)S(=O)(=O)C)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6ISR3	4-[3-Difluoromethyl-5-(5-methyl-furan-2-yl)-pyrazol-1-yl]-benzenesulfonamide	Investigative	10618038	C15H13F2N3O3S	353.3	CC1=CC=C(O1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6J5XV	4-(5-Benzo[b]thiophen-3-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10622186	C18H12F3N3O2S2	423.4	C1=CC=C2C(=C1)C(=CS2)C3=CC(=NN3C4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 = 70700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6JF0K	6-Chloro-5-phenyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53325524	C17H10ClF3O3	354.7	C1=CC=C(C=C1)C2=C(C=CC3=C2C=C(C(O3)C(F)(F)F)C(=O)O)Cl	IC50 = 68400 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6M5EN	2-Methyl-3-(4-chlorobenzyl)-6-(methylsulfonyl)-1H-indole	Investigative	11279052	C17H16ClNO2S	333.8	CC1=C(C2=C(N1)C=C(C=C2)S(=O)(=O)C)CC3=CC=C(C=C3)Cl	IC50 = 71100 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6NWJ2	3-(2,4-Dichloro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272073	C18H14Cl2O5S	413.3	CC1(C(=C(C(=O)O1)C2=C(C=C(C=C2)Cl)Cl)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6OPT3	4-Chloro-5-(4-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid	Investigative	11795928	C16H11Cl2N3O4S	412.2	C1=CC(=CC=C1C2=C(C(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6OVL3	2-(3-Methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10810738	C18H15F3N2O3S	396.4	COC1=CC=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6PTH1	3-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-thiophene	Investigative	44307492	C18H15FO2S2	346.4	CCS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6Q5XN	(E)-N,N-Dibutyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71495993	C28H37NO4	451.6	CCCCN(CCCC)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6QAN3	1,2-Difluoro-4-(4-fluoro-3-methylphenyl)-5-[4-(methylsulfonyl)phenyl]benzene	Investigative	10809519	C20H15F3O2S	376.4	CC1=C(C=CC(=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6R5SP	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dichlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051122	C26H16Cl3N5O5S	616.9	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 = 96590 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6RB0D	4-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-[1,2,3]triazole	Investigative	44383772	C15H13N3O2S	299.3	CS(=O)(=O)C1=CC=C(C=C1)C2=NNN=C2C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6S5QU	N-(3-Phenylsulfonyl-4-pyridinyl)trifluoromethanesulfonamide	Investigative	11382984	C12H9F3N2O4S2	366.3	C1=CC=C(C=C1)S(=O)(=O)C2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6SKX7	4-(Trifluoromethyl)-13lambda6-thia-5,7,19-triazatricyclo[12.2.2.12,6]nonadeca-1(17),2,4,6(19),14(18),15-hexaene 13,13-dioxide	Investigative	45273765	C16H16F3N3O2S	371.4	C1CCNC2=NC(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)CC1	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6U7KM	1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-4-methyl-1H-imidazole	Investigative	10568417	C17H15FN2O2S	330.4	CC1=CN(C(=N1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6WMJ9	4-(4-Fluoro-phenyl)-5-(4-sulfamoyl-phenyl)-thiophene-2-carboxylic acid methyl ester	Investigative	44307599	C18H14FNO4S2	391.4	COC(=O)C1=CC(=C(S1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6WN7X	3-Benzoyl-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one	Investigative	10156006	C20H18O5S	370.4	CC1(C(=C(C(=O)O1)C(=O)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6WT4L	2-Methyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	10041271	C17H15NO3S	313.4	CC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6WX8C	N-(4-Aminophenyl)-3-(trifluoromethyl)benzamide	Investigative	18543182	C14H11F3N2O	280.24	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=CC=C(C=C2)N	IC50 = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6X4EG	Sodium;2-[3-(4-fluorophenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668668	C21H20FNaO3	362.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)F)C(=O)[O-].[Na+]	IC50 = 174000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6X7UH	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-pyrrolidin-1-ylprop-2-en-1-one	Investigative	71652687	C24H27NO4	393.5	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)N3CCCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B6Z0VW	5,7-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9861581	C11H5Cl2F3O3	313.05	C1=C(C=C(C2=C1OC(C(=C2)C(=O)O)C(F)(F)F)Cl)Cl	IC50 = 145000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B71LJO	2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134154144	C21H23ClN4O2S	431	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 181970.09 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B72FEU	1,2-Bis(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10670953	C18H15F3N2O4S2	444.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B72LPH	1-[1-[(2-Chlorophenyl)methyl]-2-oxopyridin-3-yl]-3-(3-ethylphenyl)urea	Investigative	52946883	C21H20ClN3O2	381.9	CCC1=CC(=CC=C1)NC(=O)NC2=CC=CN(C2=O)CC3=CC=CC=C3Cl	Ki ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B75WEK	Huzhangoside B	Investigative	49799269	C64H104O29	1337.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B79CFS	(2S)-6-Chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	11335338; 118720947	C12H8ClF3O3	292.64	CC1=CC(=CC2=C1O[C@@H](C(=C2)C(=O)O)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B79YHC	4-Methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine	Investigative	10571870	C17H14F3N3O2S	381.4	CC1=C(C=NC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7A1HG	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(2-methylpiperidin-1-yl)prop-2-en-1-one	Investigative	71652528	C26H31NO4	421.5	CC1CCCCN1C(=O)/C=C/C2=C(C=C(C=C2OC)OC)/C=C/C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7A9WO	Fangchinoline	Investigative	73481	C37H40N2O6	608.7	CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC	IC50 = 129000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7B4ZI	2-Chloro-6-(4-chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole	Investigative	11774557	C18H12Cl2N2O2S2	423.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C=C(S3)Cl)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7DFW6	2-(2-Oxochromen-4-yl)oxyethyl 5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137647326	C28H23N3O7S	545.6	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC(=O)OC5=CC=CC=C54	IC50 ~ 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7F1JN	3-(2,4-Difluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	11222615	C19H14F2O4S	376.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=C(C=C(C=C3)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7H9JQ	4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N-methyl-benzenesulfonamide	Investigative	10834744	C17H13F4N3O2S	399.4	CNS(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7HCP2	2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)thiazole	Investigative	10154719	C17H14FNO2S2	347.4	CC1=NC(=C(S1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7HJC0	Mulberrin	Investigative	5481958	C25H26O6	422.5	CC(=CCC1=C2C(=C(C=C1O)O)C(=O)C(=C(O2)C3=C(C=C(C=C3)O)O)CC=C(C)C)C	IC50 = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7HN1I	2-[[1-(4-Nitrophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643696	C16H11N5O3S	353.4	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC=C(C=C4)[N+](=O)[O-]	IC50 = 115230 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7IZD6	1-Methylsulfanyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene	Investigative	9924251	C19H20O2S2	344.5	CSC1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7JE4M	6-Chloro-7-((ethyl(methyl)amino)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53319059	C15H15ClF3NO3	349.73	CCN(C)CC1=C(C=C2C=C(C(OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7LEI3	3-(3-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one	Investigative	10044786	C19H16O6S	372.4	CC(=O)OC1=CC=CC(=C1)C2=C(COC2=O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7LFT8	Ethyl 2-(4-chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carboxylate	Investigative	11795549	C19H17ClN2O4S	404.9	CCOC(=O)C1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7LO6I	3-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548444	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7ML3F	N-(Methylsulfonyl)-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805304	C20H26N2O6S2	454.6	CS(=O)(=O)N(C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7MV3Q	[3-(5-Chlorofuran-2-yl)-4-phenylisoxazol-5-yl]carboxylic acid	Investigative	57780765	C14H8ClNO4	289.67	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7MZ1R	2-(3-Bromophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10765731	C17H12BrF3N2O2S	445.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC=C3)Br)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7N5IX	N'-[4-[4-[(Z)-[(Z)-[3-(4-Chlorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonyl-N,N-dimethylmethanimidamide	Investigative	24816406	C28H24ClN7O3S2	606.1	CN(C)/C=N/S(=O)(=O)C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=CC=C3)/C=N\\N=C/4\\N(C(=O)CS4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7NMA6	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)pyrazine	Investigative	10735037	C17H13FN2O2S	328.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC=CN=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7OA5F	4-[(3,5-Dimethoxy-benzylidene)-amino]-benzenesulfonamide	Investigative	404320	C15H16N2O4S	320.4	COC1=CC(=CC(=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N)OC	IC50 = 109690 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7OY2I	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dimethoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127049150	C28H22ClN5O7S	608	COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl)OC	IC50 = 69250 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7QKY5	5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371411	C18H15N3O3S2	385.5	COC1=CC=CC(=C1)C2=C(SC3=NC=NN23)C4=CC=C(C=C4)S(=O)(=O)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7U1MB	2-[[1-(4-Bromophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643691	C16H11BrN4OS	387.3	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC=C(C=C4)Br	IC50 = 186110 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7VS3C	4-[3-(3-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732324	C24H23N3O2S	417.5	CC1=CC(=CC=C1)C2C3CCC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 91520 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7WRH3	1-Methoxymethyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene	Investigative	10405126	C20H22O3S	342.5	COCC1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7XJ2T	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051924	C27H20ClN5O6S	578	COC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl	IC50 = 84270 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7XW3M	N-(4-Fluorophenylsulfonyl)Nicotinamide	Investigative	57399859	C12H9FN2O3S	280.28	C1=CC(=CN=C1)C(=O)NS(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7Y5QS	3-(4-Bromophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	9823368	C19H15BrO4S	419.3	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7Y6GI	3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile	Investigative	22034379	C16H11ClN2O2S2	362.9	CS(=O)(=O)C1=CC2=C(C=C1)C(=C(N2)C#N)SC3=CC=CC=C3Cl	IC50 ~ 67000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7YCV5	2-(2-Chlorophenyl)-4-(2-thienyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22911990	C20H14ClNO2S3	432	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B7ZR1T	5-Benzyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole	Investigative	9969153	C21H18O4S	366.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2CC4=CC=CC=C4)OCO3	IC50 = 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B82VWR	4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-oxazole	Investigative	17876325	C16H12FNO3S	317.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CO2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B84VKH	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051125	C26H17ClFN5O5S	566	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC=C(C=C4)F)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 = 53430 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B85GLS	N-[6-(3,5-Dichloro-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286210	C15H12Cl2N2O3S2	403.3	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=C(C=C(C=N3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B85WLY	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051123	C26H17ClFN5O5S	566	C1=CC=C2C(=C1)C(=C(C(=O)O2)/C=N/NC(=O)C3=NN(C(=C3)C4=CC=CC=C4F)C5=CC=C(C=C5)S(=O)(=O)N)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B85XHY	N-(1-Oxo-6-o-tolylsulfanyl-indan-5-yl)-methanesulfonamide	Investigative	10545620	C17H17NO3S2	347.5	CC1=CC=CC=C1SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B87RVJ	1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole	Investigative	9954100	C20H16F4N2O2S	424.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C(=C2C3=CC=C(C=C3)F)C(F)(F)F)CC=C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B87WOC	N-(2-Aminophenyl)-3-(trifluoromethyl)benzamide	Investigative	572426	C14H11F3N2O	280.24	C1=CC=C(C(=C1)N)NC(=O)C2=CC(=CC=C2)C(F)(F)F	IC50 = 72000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8A2NW	N-[6-(4-Methyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide	Investigative	21837604	C13H12N2O4S3	356.4	CC1=CSC(=N1)SC2=C(C=C3COC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8AC1J	4-[5-Tert-butyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548266	C21H24N2O3	352.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8D3MA	4-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	8566717	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(F)(F)F)NC(=O)C2=CC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8E2LX	4-[3-(2,4-Dichlorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732337	C23H19Cl2N3O2S	472.4	C1CC2=CC=CC=C2C3=NN(C(C31)C4=C(C=C(C=C4)Cl)Cl)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8G1HN	Imidazo[2,1-b]thiazole,5-[4-(methylsulfonyl)phenyl]-6-phenyl-	Investigative	9928539	C18H14N2O2S2	354.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C=CS3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8HS0B	6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[2,3-c][1,2,4]triazole	Investigative	44371320	C17H13N3O2S2	355.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N3C=NN=C3S2)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8I4QA	6-Chloro-8-(4-(methylsulfonamido)phenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53320474	C18H13ClF3NO5S	447.8	CS(=O)(=O)NC1=CC=C(C=C1)C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8I6ED	4-((3,4-Dihydroxyphenyl)diazenyl)benzenesulfonamide	Investigative	404196	C12H11N3O4S	293.3	C1=CC(=CC=C1N=NC2=CC(=C(C=C2)O)O)S(=O)(=O)N	IC50 = 59960 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8KE5B	2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	10433546	C22H15ClFNO2S2	443.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8LX1B	[5-(4-Methanesulfonyl-phenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl]-acetic acid	Investigative	44400364	C20H19NO4S	369.4	CC1=C(C=C(N1C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)CC(=O)O	IC50 = 132000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8M9TE	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(4-methylpiperidin-1-yl)prop-2-en-1-one	Investigative	71652530	C26H31NO4	421.5	CC1CCN(CC1)C(=O)/C=C/C2=C(C=C(C=C2OC)OC)/C=C/C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8MAB3	4-[2-(3-Fluoro-5-methoxy-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide	Investigative	10740567	C17H13F4N3O3S	415.4	COC1=CC(=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8MSW5	2-(4-Fluoro-phenyl)-1-(3-methanesulfonyl-phenyl)-1H-pyrrole	Investigative	10710438	C17H14FNO2S	315.4	CS(=O)(=O)C1=CC=CC(=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8NAC4	2-[3-(Methoxymethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10669268	C19H17F3N2O3S	410.4	COCC1=CC(=CC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8NJQ1	3-(3-Chloro-4-fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272281	C18H14ClFO5S	396.8	CC1(C(=C(C(=O)O1)C2=CC(=C(C=C2)F)Cl)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 = 81000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8OB0C	5-Cyclohexylidenemethyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole	Investigative	10133748	C21H22O4S	370.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2C=C4CCCCC4)OCO3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8P0FG	2-(3,7-Dimethylocta-2,6-dien-1-yl)-6-methylbenzo-1,4-quinone	Investigative	642530	C17H22O2	258.35	CC1=CC(=O)C=C(C1=O)C/C=C(\\C)/CCC=C(C)C	IC50 = 64300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8PD7R	4-[3-(5-Chloro-furan-2-yl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide	Investigative	11382191	C14H11ClN2O4S	338.8	CC1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8PLY0	2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid	Investigative	11777274	C16H15FO2	258.29	CC(C)(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8POB9	3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methoxy-5-methyl-5H-furan-2-one	Investigative	21472747	C19H17FO5S	376.4	CC1(C(=C(C(=O)O1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)OC	IC50 = 57000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8QBJ5	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-piperidin-1-ylprop-2-en-1-one	Investigative	71652369	C25H29NO4	407.5	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)N3CCCCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8QYV1	1-(3-Chloro-4-methanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10665504	C17H13ClFNO2S	349.8	CS(=O)(=O)C1=C(C=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8S6VI	N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286326	C15H16N2O3S3	368.5	CCC1=CSC(=N1)SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8SGL7	4-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzonitrile	Investigative	10448879	C19H17NO2S	323.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)C#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8USR6	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-naphthalen-2-yl-pyran-4-one	Investigative	11474778	C23H18O4S	390.5	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC4=CC=CC=C4C=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8V2LE	2-[3-Fluoro-5-(trifluoromethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10742264	C18H11F7N2O2S	452.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC(=C3)F)C(F)(F)F)C(F)(F)F	IC50 = 67000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8VN6L	2-Methyl-3-(2-chlorobenzyl)-6-(methylsulfonyl)-1H-indole	Investigative	9967467	C17H16ClNO2S	333.8	CC1=C(C2=C(N1)C=C(C=C2)S(=O)(=O)C)CC3=CC=CC=C3Cl	IC50 = 118000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8VQD6	(S)-6,8-Dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	10038859	C13H11F3O3	272.22	CC1=CC(=C2C(=C1)C=C([C@H](O2)C(F)(F)F)C(=O)O)C	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8VY2W	2-[[1-(3-Nitrophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643695	C16H11N5O3S	353.4	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC(=CC=C4)[N+](=O)[O-]	IC50 = 103520 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8Y5CG	(S)-8-Propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52943858	C15H12F6O4	370.24	CCCC1=CC(=CC2=C1O[C@@H](C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 = 71700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8YRG4	4-[2-[3-(Trifluoromethyl)-4-fluorophenyl]-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10786241	C19H16F4O2S	384.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B8YTV0	N-[6-(3-Chloro-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286540	C15H13ClN2O3S2	368.9	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=C(C=CC=N3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B90AYG	4-[(3,4-Dimethoxy-benzylidene)-amino]-benzenesulfonamide	Investigative	404323	C15H16N2O4S	320.4	COC1=C(C=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N)OC	IC50 = 110270 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B90AZM	1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805051	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B92EZH	N-[(2S)-2-(3,4-Dihydroxyphenyl)-2-[(2R)-2,3-dihydroxypropoxy]ethyl]acetamide	Investigative	118715217	C13H19NO6	285.29	CC(=O)NC[C@H](C1=CC(=C(C=C1)O)O)OC[C@@H](CO)O	IC50 = 117000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B92IOE	4-(4-(Methylsulfonyl)phenyl)-N-p-tolyl-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45267769	C19H16F3N3O2S	407.4	CC1=CC=C(C=C1)NC2=NC(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B93RBW	Sodium;2-[2-(4-methoxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56675535	C22H23NaO4	374.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC)C(=O)[O-].[Na+]	IC50 = 74000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B94PLI	Chembl4126559	Investigative	145960841	C18H19N3O2	309.4	CCN\\1C(=CC/C1=N/N=C(\\C)/C2=CC3=CC=CC=C3OC2=O)C	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B96XPI	8-Fluoro-2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-5-[(4-methylsulfonylphenyl)methyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;hydrochloride	Investigative	46906743	C34H39ClF2N2O5S	661.2	COC1(CCOCC1)C2=CC(=CC(=C2)F)OCCCN3CCC4=C(C3)C5=C(N4CC6=CC=C(C=C6)S(=O)(=O)C)C=CC(=C5)F.Cl	IC50 = 180300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B98GSH	1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazole-4-carbonitrile	Investigative	10853420	C16H12N4O2S	324.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CN=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B98PIR	4-[5-(3,5-Difluoro-4-methoxy-phenyl)-3-difluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10835645	C17H13F4N3O3S	415.4	COC1=C(C=C(C=C1F)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F	IC50 = 63600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9A6GH	N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide	Investigative	44286327	C13H12N2O4S4	388.5	CSC1=CSC(=N1)SC2=C(C=C3COC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9BSZ2	2-Chloro-1-fluoro-4-[2-(4-methylsulfonylphenyl)phenyl]benzene	Investigative	10832407	C19H14ClFO2S	360.8	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CC(=C(C=C3)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9CB4P	4-[5-Tert-butyl-3-(4-nitrophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548267	C20H21N3O4	367.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)[N+](=O)[O-])C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9DZ0Y	5-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzo[1,3]dioxole	Investigative	10712340	C19H18O4S	342.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC4=C(C=C3)OCO4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9E8BQ	1,2-Difluoro-4-(4-methylphenyl)-5-(4-methylsulfonylphenyl)benzene	Investigative	10832238	C20H16F2O2S	358.4	CC1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9EKJ4	1,2,3,4-Tetrafluoro-5-(4-fluorophenyl)-6-(4-methylsulfonylphenyl)benzene	Investigative	11795129	C19H11F5O2S	398.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=C(C(=C2F)F)F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9EW6L	4-[5-(2-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548445	C24H22N2O4	402.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9F6SW	1-(4-Methanesulfonylphenyl)-3-[(3-nitro)phenoxymethyl]-5-phenyl-1H-pyrazole	Investigative	11282341	C23H19N3O5S	449.5	CS(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)COC3=CC=CC(=C3)[N+](=O)[O-])C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9GTO2	(E)-N-Cyclohexyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71495781	C26H31NO4	421.5	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)NC3CCCCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9H4PV	N-Benzyl-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine	Investigative	45272855	C24H20FN3O2S	433.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)NCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9HYQ1	3-(4-Fluorophenyl)-2-[4-(methanesulfonyl)phenyl]thiophene	Investigative	18946587	C17H13FO2S2	332.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=CS2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9I8KU	4-[5-(3-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68293474	C24H22N2O4	402.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC(=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9I8WF	4-[3-(2,4-Dichlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732347	C22H17Cl2N3O3S	474.4	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=C(C=C(C=C5)Cl)Cl	IC50 = 96330 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9JEF1	1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole	Investigative	2765724	C18H16FNO2S	329.4	CC1=CC=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9M2PS	4-[[4-(Dimethylamino)phenyl]iminomethyl]benzenesulfonamide	Investigative	44456656	C15H17N3O2S	303.4	CN(C)C1=CC=C(C=C1)N=CC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 64420 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9M4DI	1-(4-Methylsulfonylphenyl)-2-thiophen-2-yl-4-(trifluoromethyl)imidazole	Investigative	11793632	C15H11F3N2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=CS3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9MAH7	2,3-Dimethyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline	Investigative	10020588	C18H18FNO3S	347.4	CC1C(=C(ON1C)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9MJ1F	1-(4-Fluoro-benzyl)-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10688742	C19H18FNO2S	343.4	CC1=CC=C(N1CC2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9NG5C	4-[5-Tert-butyl-3-(2-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548632	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9NGL4	1,2-Dichloro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)benzene	Investigative	10644380	C19H13Cl2FO2S	395.3	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)F)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9O2UP	4-(4-Methylsulfonylphenyl)-N-(oxan-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	9822357	C17H18F3N3O3S	401.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCOCC3)C(F)(F)F	IC50 ~ 91629 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9OTD8	3-Methoxy-5-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine	Investigative	10786970	C17H14F3N3O3S	397.4	COC1=CN=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9P6RA	4-[2-(3-Fluoro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	9902810	C19H19FO3S	346.4	COC1=C(C=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9PMX0	2,3-Dichloro-6-(4-chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole	Investigative	44365341	C18H11Cl3N2O2S2	457.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C(=C(S3)Cl)Cl)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9PQI4	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-spiro[4.4]non-2-ene	Investigative	10523190	C22H23FO2S	370.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CCCC3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9R3XB	3-[3-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid	Investigative	122192741	C13H10F5NO2S	339.28	C1=CC(=CC(=C1)NC2=CC(=CC=C2)S(F)(F)(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9RFE7	3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118705855	C19H17F3N2O4S	426.4	CS(=O)(=O)C1=CC=C(C=C1)N2C(CC(=N2)C(F)(F)F)C3=CC4=C(C=C3)OCCO4	IC50 = 64910 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9RO3C	2-(4-Chlorophenyl)-4-methyl-1-(4-(methylsulfonyl)phenyl)-1H-imidazole	Investigative	9946200	C17H15ClN2O2S	346.8	CC1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9TB5D	2-Benzyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912028	C23H18FNO2S2	423.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)CC3=CC=CC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9TN1H	2-Isopropoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine	Investigative	45270285	C15H15F3N2O3S	360.4	CC(C)OC1=NC(=CC(=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 = 52556 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9TSV8	4-[5-(3,5-Dichloro-4-methoxy-phenyl)-3-difluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10575436	C17H13Cl2F2N3O3S	448.3	COC1=C(C=C(C=C1Cl)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)Cl	IC50 = 77000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9TZ4H	11S,16R-Dihydroxyoctadeca-9Z,17-dien-12,14-diynoic-1-ylacetate	Investigative	44584247	C20H26O5	346.4	CC(=O)OC(=O)CCCCCCC/C=C/[C@@H](C#CC#C[C@@H](C=C)O)O	IC50 = 73000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9VF7W	2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-pyrazol-1-yl]-N-phenyl-acetamide	Investigative	10118686	C25H19F4N3O3S	517.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C(=C2C3=CC=C(C=C3)F)C(F)(F)F)CC(=O)NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9VRC8	2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfonamide	Investigative	11099739	C16H21N3O3S	335.4	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)N)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9XN7C	3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile	Investigative	9968075	C16H11FN2O2S2	346.4	CS(=O)(=O)C1=CC2=C(C=C1)C(=C(N2)C#N)SC3=CC=C(C=C3)F	IC50 ~ 125000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9Y6AQ	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-trifluoromethyl-phenoxy)-pyran-4-one	Investigative	11281693	C20H15F3O5S	424.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	B9YD2X	1-(4-Methanesulfonyl-phenyl)-2-(2-methoxy-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10596883	C18H15F3N2O3S	396.4	COC1=CC=CC=C1C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA05DF	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	44395210	C19H14FN3O2S	367.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C3C=CC=NN3N=C2C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA0Q7U	(1R,4Ar,7S)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid	Investigative	9861219	C20H30O2	302.5	C[C@@]12CCC[C@@](C1CCC3C2=CC[C@](C3)(C)C=C)(C)C(=O)O	IC50 = 116400 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA1N7Z	2-(2-Fluorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10810038	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=CC=C3F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA29MR	[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-acetic acid	Investigative	44383922	C19H15FO4S2	390.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2C3=CC=C(C=C3)F)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA2V5L	5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-phenyl-5H-furan-2-one	Investigative	21472753	C18H16O5S	344.4	CC1(C(=C(C(=O)O1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 90000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA37NI	2-{[2-Nitro-5-(trifluoromethyl)phenyl]amino}benzoic acid	Investigative	45117711	C14H9F3N2O4	326.23	C1=CC=C(C(=C1)C(=O)O)NC2=C(C=CC(=C2)C(F)(F)F)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA38RK	3-(3-Fluoro-4-methoxy-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran	Investigative	44316044	C22H17FO4S	396.4	COC1=C(C=C(C=C1)C2=C(OC3=CC=CC=C32)C4=CC=C(C=C4)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA3G9Y	Chembl4245581	Investigative	145985054	C33H23FN2O6	562.5	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OCC(=O)OCC4=NN(C(=C4)C5=CC=C(C=C5)F)C6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA5SR2	3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1H-indene	Investigative	44316126	C22H17FO2S	364.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C3=CC=CC=C3C2)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA9DF5	6-Bromo-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	58934890	C12H8BrF3O3	337.09	CC1=CC(=CC2=C1OC(C(=C2)C(=O)O)C(F)(F)F)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BA9MG4	1-[2-(3-Chloro-4-fluorophenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene	Investigative	10784091	C18H16ClFO2S	350.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BABX61	6-Methoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9965352	C12H9F3O4	274.19	COC1=CC2=C(C=C1)OC(C(=C2)C(=O)O)C(F)(F)F	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BABZ42	N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide	Investigative	10854191	C15H14N2O3S2	334.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAL2J3	4-[5-Tert-butyl-2-(4-carboxyphenyl)-3,4-dihydropyrazol-3-yl]-3-methoxybenzoic acid	Investigative	129012347	C22H24N2O5	396.4	CC(C)(C)C1=NN(C(C1)C2=C(C=C(C=C2)C(=O)O)OC)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAQ3W5	3-(2-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	9950666	C19H15FO4S	358.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAR9P4	4-[2-(3,4-Dichlorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10761459	C18H16Cl2O2S	367.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAS3F1	(1R,4Ar,7S)-7-(2,2-Difluoro-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid	Investigative	44368376	C20H30F2O2	340.4	C[C@@]12CCC[C@@](C1CCC3C2=CC[C@](C3)(C)CC(F)F)(C)C(=O)O	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAU1G4	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127049135	C27H20ClN5O5S	562	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl	IC50 = 89530 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAU64H	2-(4-Methanesulfonyl-phenyl)-3-phenyl-benzo[d]imidazo[2,1-b]thiazole	Investigative	44365569	C22H16N2O2S2	404.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N3C4=CC=CC=C4SC3=N2)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAUI65	4-(3-Fluoromethyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10520508	C16H14FN3O2S	331.4	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)CF	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAW53L	2-Methyl-3-(2,4-difluorobenzyl)-6-(methylsulfonyl)-1H-indole	Investigative	10449604	C17H15F2NO2S	335.4	CC1=C(C2=C(N1)C=C(C=C2)S(=O)(=O)C)CC3=C(C=C(C=C3)F)F	IC50 = 98000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BAZ69R	6-Chloro-5-ethoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53323225	C13H10ClF3O4	322.66	CCOC1=C(C=CC2=C1C=C(C(O2)C(F)(F)F)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB0M4S	4-[5-(2,5-Dichlorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10526904	C16H10Cl2F3N3O2S	436.2	C1=CC(=CC=C1N2C(=CC(=N2)C(F)(F)F)C3=C(C=CC(=C3)Cl)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB2X9W	6,8-Dibromo-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	71509614	C13H9Br2F3O3	436.05	[2H]C([2H])([2H])C1=C2C=C(C(OC2=C(C(=C1Br)C([2H])([2H])[2H])Br)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB2ZF7	2-(Benzenesulfonyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706114	C18H15F3N2O4S	412.4	C1COC2=C(O1)C=CC(=C2)C3CC(=NN3S(=O)(=O)C4=CC=CC=C4)C(F)(F)F	IC50 = 105600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB34NM	3-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-pyrrol-2-yl]-propionic acid	Investigative	10524261	C20H18FNO4S	387.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(N2C3=CC=C(C=C3)F)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB39MV	6-Ethynyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	21883501	C13H7F3O3	268.19	C#CC1=CC2=C(C=C1)OC(C(=C2)C(=O)O)C(F)(F)F	IC50 = 94200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB3C9A	N-[1-Oxo-6-(4-vinyl-thiazol-2-ylsulfanyl)-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide	Investigative	44286343	C14H12N2O4S3	368.5	CS(=O)(=O)NC1=C(C=C2C(=C1)COC2=O)SC3=NC(=CS3)C=C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB3F6A	6-Chloro-5-ethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53326920	C13H10ClF3O3	306.66	CCC1=C(C=CC2=C1C=C(C(O2)C(F)(F)F)C(=O)O)Cl	IC50 = 66700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB4I2P	(R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid	Investigative	13148390	C15H20O3	248.32	C[C@H](C1=CC=C(C=C1)C[C@@H]2CCC[C@H]2O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB8HN9	1-[4,4-Diethyl-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene	Investigative	10022177	C22H25FO2S	372.5	CCC1(CC(=C(C1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)CC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BB9H6Q	5-Chloro-3-[[1-(2-fluorophenyl)triazol-4-yl]methyl]-1,3-benzoxazol-2-one	Investigative	76328049	C16H10ClFN4O2	344.73	C1=CC=C(C(=C1)N2C=C(N=N2)CN3C4=C(C=CC(=C4)Cl)OC3=O)F	IC50 = 138250 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBEL65	1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]imidazole	Investigative	10646465	C18H12F6N2O2S	434.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC=C3)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBJ62V	1,2-Difluoro-4-(3-fluoro-4-methoxyphenyl)-5-[4-(methylsulfonyl)phenyl]benzene	Investigative	10548520	C20H15F3O3S	392.4	COC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBJL20	6-(4,5-Difluoro-4''-methanesulfonyl-biphenyl-2-yl)-2,3-dihydro-benzo[1,4]dioxine	Investigative	10597216	C21H16F2O4S	402.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC4=C(C=C3)OCCO4)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBKE12	3-(4-Methoxyphenyl)-2-(4-(methylsulfonyl)phenyl)thiazolidin-4-one	Investigative	44443330	C17H17NO4S2	363.5	COC1=CC=C(C=C1)N2C(SCC2=O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBL97Z	4-[5-(4-Nitrophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10201726	C16H11F3N4O4S	412.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBSZ27	Daphnetin	Investigative	5280569	C9H6O4	178.14	C1=CC(=C(C2=C1C=CC(=O)O2)O)O	IC50 = 140000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBT41M	1-[4-(Methylsulfonyl)phenyl]-2-[3-(dimethylamino)-4-chlorophenyl]-4-(trifluoromethyl)-1H-imidazole	Investigative	10623138	C19H17ClF3N3O2S	443.9	CN(C)C1=C(C=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBV62L	N-[6-(4-Fluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	10689279	C16H14FNO3S2	351.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBVW31	1-(3-Chloro-4-methoxyphenyl)-4,5-difluoro-2-[4-(methylsulfonyl)phenyl]benzene	Investigative	10716420	C20H15ClF2O3S	408.8	COC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBXT45	3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3'']bipyridinyl	Investigative	9967049	C18H16N2O2S	324.4	CC1=CC(=C(N=C1)C2=CN=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 59000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BBYP54	5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole-3-carboxylic acid	Investigative	44365531	C19H14N2O4S2	398.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C3N2C(=CS3)C(=O)O)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC09TV	2-(3,5-Dichloro-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10766586	C18H13Cl2F3N2O3S	465.3	COC1=C(C=C(C=C1Cl)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC0R9Z	2-(3-Fluoro-4-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10501037	C18H14F4N2O2S	398.4	CC1=C(C=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC0XF2	6-(4-Methanesulfonyl-phenyl)-2,3-dimethyl-5-phenyl-imidazo[2,1-b]thiazole	Investigative	44365508	C20H18N2O2S2	382.5	CC1=C(SC2=NC(=C(N12)C3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)C)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC19DU	6-[4-(Methylsulfonyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]spiro[2.4]hept-5-ene	Investigative	10597571	C21H19F3O3S	408.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC24YI	4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(pyridin-2-ylmethyl)pyrimidine	Investigative	45271129	C23H18FN3O2S	419.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)CC4=CC=CC=N4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC31BH	1-Methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene	Investigative	10403254	C19H20O2S	312.4	CC1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC5TE1	4-(2-Methyl-5-phenyl-4-thiazolyl)benzenesulfonamide	Investigative	17816357	C16H14N2O2S2	330.4	CC1=NC(=C(S1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 72500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC6UH3	1H-Pyrrole, 2-methyl-5-[4-(methylsulfonyl)phenyl]-	Investigative	10799759	C12H13NO2S	235.3	CC1=CC=C(N1)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC82MP	(R)-6-Chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52948912	C13H10ClF3O3	306.66	CC1=C(C=C2C=C([C@@H](OC2=C1C)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC84KO	3-(4-Iodo-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one	Investigative	11340629	C19H15IO5S	482.3	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)I	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC8WR5	2-[[1-(4-Methoxyphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643687	C17H14N4O2S	338.4	COC1=CC=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 89370 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC8Y5F	3-Phenyl-4-(4-azidophenyl)furan-2(5H)-one	Investigative	10084869	C16H11N3O2	277.28	C1C(=C(C(=O)O1)C2=CC=CC=C2)C3=CC=C(C=C3)N=[N+]=[N-]	IC50 = 159720 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC8YS0	2-Methyl-5-(4-methylsulfonylphenyl)-1-phenyl-3-(2-propoxyethyl)pyrrole	Investigative	24951013	C23H27NO3S	397.5	CCCOCCC1=C(N(C(=C1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3)C	IC50 = 86000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC98EZ	3-(4-Fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	21472741	C18H15FO5S	362.4	CC1(C(=C(C(=O)O1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BC9E1L	3-(3-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one	Investigative	9923656	C17H13FO4S	332.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC(=CC=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCB5S0	2-[6-Methoxy-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid	Investigative	18542252	C18H16N2O4	324.3	CC1=CC(=NC=C1)C(=O)C2=C(C3=C(N2)C=C(C=C3)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCKV64	4-[3-(2-Fluorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732342	C22H18FN3O3S	423.5	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=CC=CC=C5F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCR7J5	6-Hydroxymethyletoricoxib	Investigative	44266438	C18H15ClN2O3S	374.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CN=C(C=C3)CO	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCS4L6	Ciwujianoside C3	Investigative	21626481	C53H86O21	1059.2	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCS64T	2-Ethyl-1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10807315	C19H18FNO2S	343.4	CCC1=CC=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCX8P6	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-p-tolyl-pyran-4-one	Investigative	9863426	C20H18O4S	354.4	CC1=CC=C(C=C1)C2=C(OC(=CC2=O)C)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BCXK70	1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)benzene	Investigative	9905412	C19H15FO2S	326.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD0L6N	4-[3-Cyano-5-(4-fluorophenyl)pyrazol-1-yl]benzenesulfonamide	Investigative	9967867	C16H11FN4O2S	342.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C#N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD0M3X	1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-2,4-dichlorobenzene	Investigative	10292387	C18H16Cl2O2S	367.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=C(C=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD1T4O	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051925	C27H20ClN5O6S	578	COC1=CC=CC(=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD25RC	2-(4-Tert-Butylphenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	44271105	C26H24FNO2S2	465.6	CC(C)(C)C1=CC=C(C=C1)C2=NC(=C(S2)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD27MZ	1-(2-(4-(4-(Methylsulfonyl)-2-nitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805054	C19H22N2O6S	406.5	CS(=O)(=O)C1=CC(=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD3YA2	6-Bromo-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	78091888	C13H10BrF3O3	351.11	CC1=CC2=C(C=C(C(O2)C(F)(F)F)C(=O)O)C(=C1Br)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD4G2Z	6-Chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	51003556	C19H14ClF3O4	398.8	CC1=C(C=CC(=C1)C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD5IK2	1-Ethyl-4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrazole	Investigative	9844547	C19H16F4N2O2S	412.4	CCN1C(=C(C(=N1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD5Q3N	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole	Investigative	15380222	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)C2=NNC(=C2C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD6Z4S	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-ethoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127051106	C28H22ClN5O6S	592	CCOC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl	IC50 = 78540 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD79TN	5,5-Dimethyl-3-(1-methylethoxy)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone	Investigative	9840237	C16H20O5S	324.4	CC(C)OC1=C(C(OC1=O)(C)C)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD7Z3R	2-(4-Chloro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10812568	C18H14ClF3N2O3S	430.8	COC1=C(C=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD8I2Z	2-Phenyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	22624559	C22H23NO3S	381.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(O2)C3=CC=CC=C3)C4CCCCC4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD94ZN	4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-benzenesulfonamide	Investigative	10936619	C16H20N2O4S	336.4	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)O)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BD98WP	Sodium;2-[2-nitro-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668664	C15H16NNaO5	313.28	CC(C1=C(C=C(C=C1)CC2CCCC2=O)[N+](=O)[O-])C(=O)[O-].[Na+]	IC50 = 93000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDB47L	2-[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]acetonitrile	Investigative	10547228	C18H14ClN3O2S	371.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CC#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDE9W0	3-Nitrooxypropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate	Investigative	57780777	C17H13ClN2O7	392.7	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)C(=O)OCCCO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDFN79	(S)-3-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-2-methyl-butan-2-ol	Investigative	15887864	C18H20F3NO4S	403.4	C[C@@H](C(C)(C)O)OC1=C(C=C(C=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDJ0F2	4-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid	Investigative	10808453	C16H12N2O6S	360.3	C1=CC(=CC=C1C2=COC(=O)N2C3=CC=C(C=C3)C(=O)O)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDL67T	4-{2-[4-(1-Hydroxy-1-methyl-ethyl)-phenyl]-thiophen-3-yl}-benzenesulfonamide	Investigative	20658522	C19H19NO3S2	373.5	CC(C)(C1=CC=C(C=C1)C2=C(C=CS2)C3=CC=C(C=C3)S(=O)(=O)N)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDMO63	(E)-N-Tert-butyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71652199	C24H29NO4	395.5	CC(C)(C)NC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDN28B	4-(5-Benzofuran-2-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10835226	C18H12F3N3O3S	407.4	C1=CC=C2C(=C1)C=C(O2)C3=CC(=NN3C4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDN2B6	N-(4-Methylphenyl)sulfonylpyridine-2-carboxamide	Investigative	1500235	C13H12N2O3S	276.31	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CC=CC=N2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDP45T	1-[2-(4-Phenoxyphenoxy)ethyl]pyrrolidine	Investigative	9993978	C18H21NO2	283.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDP94B	4-[5-(4-Chlorophenyl)-3-(cyanomethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10833127	C17H13ClN4O2S	372.8	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)CC#N)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDU0J6	N,N-Dimethyl-N'-[4-[4-[(Z)-[(Z)-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonylmethanimidamide	Investigative	24816405	C29H27N7O3S2	585.7	CC1=CC=C(C=C1)N\\2C(=O)CS/C2=N\\N=C/C3=CN(N=C3C4=CC=CC=C4)C5=CC=C(C=C5)S(=O)(=O)/N=C/N(C)C	IC50 = 87120 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDXJ05	2-(2-Chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)thiazole	Investigative	9933112	C22H15ClFNO2S2	443.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BDZ94G	(E)-2-Methyl-5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazin-3(2H)-one	Investigative	44408022	C20H16N2O2	316.4	CN1C(=O)C=C(C(=N1)C2=CC=CC=C2)/C=C/C(=O)C3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE0GS8	2-[[1-(2-Chloropyridin-3-yl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643686	C15H10ClN5OS	343.8	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=C(N=CC=C4)Cl	IC50 = 102660 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE0XN9	5-[4,5-Difluoro-2-(4-methylsulfonylphenyl)phenyl]-2-methylpyridine	Investigative	10570444	C19H15F2NO2S	359.4	CC1=NC=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE0ZS5	2-[(1-Phenyltriazol-4-yl)methylsulfanyl]-1,3-benzoxazole	Investigative	90643697	C16H12N4OS	308.4	C1=CC=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 107250 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE1D7P	(1R,4Ar,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid amide	Investigative	9839351	C20H31NO	301.5	C[C@@]12CCC[C@@](C1CCC3C2=CC[C@](C3)(C)C=C)(C)C(=O)N	IC50 = 147500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE1NV2	4-[3-(3-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732329	C23H20FN3O2S	421.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC(=CC=C4)F)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE1XN0	(+)-Gallocatechin	Investigative	65084	C15H14O7	306.27	C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O	IC50 = 95000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE1ZS9	4-[3-(4-Chlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732344	C22H18ClN3O3S	439.9	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE41BL	4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N,N-dimethyl-benzenesulfonamide	Investigative	10549657	C18H15F4N3O2S	413.4	CN(C)S(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE4T8W	4-[3-[4-(Trifluoromethyl)phenyl]-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732336	C24H20F3N3O2S	471.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=C(C=C4)C(F)(F)F)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE4XR1	6,8-Dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	11500030	C13H11F3O3	272.22	CC1=CC(=C2C(=C1)C=C(C(O2)C(F)(F)F)C(=O)O)C	IC50 = 169000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE7AN2	2-(4-Chlorophenyl)-4-(fluoromethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	11793188	C17H14ClFN2O2S	364.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CF	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE7PD5	1-(2-(4-(2,4-Dinitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49804920	C18H19N3O6	373.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE7ZP8	4-[2-(3,4-Difluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10664448	C18H16F2O2S	334.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE92HX	3-Cyclopentyloxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one	Investigative	15521080	C18H22O5S	350.4	CC1(C(=C(C(=O)O1)OC2CCCC2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BE9TN6	4,6-Dimethyl-2-[1-oxo-1-(4-phenylpiperazin-1-yl)butan-2-yl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134152691	C22H26N4O2S	410.5	CCC(C(=O)N1CCN(CC1)C2=CC=CC=C2)N3C(=O)C4=C(S3)N=C(C=C4C)C	IC50 = 138038.43 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BEK17V	4-(4-(Methylsulfonyl)phenyl)-N-phenyl-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45268649	C18H14F3N3O2S	393.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3=CC=CC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BEMZ75	4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid	Investigative	66548636	C19H21ClN2O3S	392.9	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BEQI79	4-[2-(3,4-Dimethoxyphenyl)-4,5-difluorophenyl]benzenesulfonamide	Investigative	10621294	C20H17F2NO4S	405.4	COC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)N)F)F)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BERM13	4-[1-[2-(Cyclopentylamino)pyrimidin-4-yl]-2-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-1-methylpiperidin-4-ol	Investigative	10005638	C25H29F3N6O	486.5	CN1CCC(CC1)(C2=CN(C(=N2)C3=CC(=CC=C3)C(F)(F)F)C4=NC(=NC=C4)NC5CCCC5)O	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BEU8G6	N-[6-(5-Methyl-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286194	C16H16N2O3S2	348.4	CC1=CN=C(C=C1)SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF0UP3	7-Methoxy-3-(3'',5''-dimethoxyphenyl)coumarin	Investigative	44406315	C18H16O5	312.3	COC1=CC2=C(C=C1)C=C(C(=O)O2)C3=CC(=CC(=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF36UX	Chembl4129191	Investigative	145960726	C17H17N3O3	311.33	CC1C/C(=N/N=C(\\C)/C2=CC3=CC=CC=C3OC2=O)/N(C1=O)C	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF49WE	2-(4-Chlorobenzyloxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine	Investigative	44292819	C20H15ClF3NO3S	441.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)C(F)(F)F)OCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF4GR7	4-[3-Difluoromethyl-5-(2,5-dimethyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide	Investigative	10643308	C18H17F2N3O2S	377.4	CC1=CC(=C(C=C1)C)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF4Z9J	6,8-Dibromo-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	78091940	C13H9Br2F3O3	430.01	CC1=C2C=C(C(OC2=C(C(=C1Br)C)Br)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF56QS	4-(4-(Methylsulfonyl)phenyl)-N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45271980	C17H19F3N4O2S	400.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCNCC3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF6XM7	4-[3-(2-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732323	C24H23N3O2S	417.5	CC1=CC=CC=C1C2C3CCC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 99870 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF78TK	2-[[2-Anilinoethyl(methyl)amino]methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	11544686	C18H22N4OS	342.5	CC1=CC(=NC2=C1C(=O)N(S2)CN(C)CCNC3=CC=CC=C3)C	IC50 = 173780.08 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BF7EY0	3-[5-Chloro-3-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-4-methyl-pyridine	Investigative	44343879	C16H14ClN3O2S	347.8	CC1=C(C=NC=C1)C2=C(N=CN2C3=CC=C(C=C3)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFG5Z0	4-[5-Pyridin-2-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10690364	C15H11F3N4O2S	368.3	C1=CC=NC(=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 93300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFGO19	4-[3-(2-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732328	C23H20FN3O2S	421.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=CC=C4F)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFHB46	3-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)thiazolidin-4-one	Investigative	10405693	C16H14FNO3S2	351.4	CS(=O)(=O)C1=CC=C(C=C1)C2N(C(=O)CS2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFN15Y	2-(4-Chlorophenyl)-4-(difluoromethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10762494	C17H13ClF2N2O2S	382.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFP4V1	4-[3-(4-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732325	C24H23N3O2S	417.5	CC1=CC=C(C=C1)C2C3CCC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 88380 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFRB04	Chembl4241591	Investigative	145984992	C34H25ClN2O6	593	CC1=CC=C(C=C1)N2C(=CC(=N2)COC(=O)COC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=CC=C5)O)C6=CC=C(C=C6)Cl	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFSM34	2-(4-Fluoro-phenyl)-6-isopropoxy-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	44395250	C22H20FN3O3S	425.5	CC(C)OC1=NN2C(=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)S(=O)(=O)C)C=C1	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFU91R	2,4,6-Trimethyl-3-(5-methyl-4-phenyl-isoxazol-3-yl)-benzenesulfonamide	Investigative	11302745	C19H20N2O3S	356.4	CC1=CC(=C(C(=C1C2=NOC(=C2C3=CC=CC=C3)C)C)S(=O)(=O)N)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFUN84	[4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2-methyl-3H-benzoimidazol-5-yl)-methanone	Investigative	44346322	C22H17F2N3O2	393.4	CC1=NC2=C(N1)C=C(C(=C2)OC)C(=O)C3=CC=C(C=C3)NC4=C(C=C(C=C4)F)F	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BFX2Q4	N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide	Investigative	9884371	C13H12N2O3S3	340.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=NC=CS3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG0E8I	3-[4-(Difluoromethyl)-1-(4-methylsulfonylphenyl)imidazol-2-yl]pyridine	Investigative	10545724	C16H13F2N3O2S	349.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CN=CC=C3)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG2A9V	3-[1-(3-Chloro-phenoxy)-2,2,2-trifluoro-ethyl]-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole	Investigative	10816219	C26H20ClF4NO3S	538	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(C(F)(F)F)OC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG2F9T	5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-oxazole	Investigative	17876403	C16H12FNO3S	317.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(OC=N2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG37RA	3-(4-Chlorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	9842547	C19H15ClO4S	374.8	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG3UL5	Benzenesulfonamide, 4-[(4-hydroxy-3-methoxyphenyl)azo]-	Investigative	404197	C13H13N3O4S	307.33	COC1=C(C=CC(=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG4LE6	4-[2-(3,5-Dichloro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	11795080	C19H18Cl2O3S	397.3	COC1=C(C=C(C=C1Cl)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG4PR5	(S)-6-Chloro-7-(isobutyl(methyl)amino)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53321886	C16H17ClF3NO3	363.76	CC(C)CN(C)C1=C(C=C2C=C([C@H](OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG53ST	3-(4-Fluorophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	11234177	C19H15FO5S	374.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG8CK2	4-[2-(3,4,5-Trifluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10641720	C18H15F3O2S	352.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C(=C3)F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG8D0L	4-(4,6-Dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)butanoic acid	Investigative	134135733	C12H14N2O3S	266.32	CC1=CC(=NC2=C1C(=O)N(S2)CCCC(=O)O)C	IC50 = 194984.46 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG8DX5	(3S,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihydro-furan-2-one	Investigative	44323766	C17H16O4S	316.4	CS(=O)(=O)C1=CC=C(C=C1)[C@H]2COC(=O)[C@@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG8S0P	2-Methyl-5-(4-methylsulfonylphenyl)-1-[4-(trifluoromethyl)phenyl]pyrrole	Investigative	10619703	C19H16F3NO2S	379.4	CC1=CC=C(N1C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG8ZO2	2-(2-Chloro-6-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10645484	C18H14ClF3N2O2S	414.8	CC1=C(C(=CC=C1)Cl)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BG9K2L	3-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline	Investigative	11794212	C17H14F3N3O2S	381.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC=C3)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGHU48	1-Phenyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole	Investigative	10805003	C18H17NO2S	311.4	CC1=CC=C(N1C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGI7H3	6-Chloro-7-((2,5-dimethylpyrrolidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53323226	C18H19ClF3NO3	389.8	CC1CCC(N1CC2=C(C=C3C=C(C(OC3=C2)C(F)(F)F)C(=O)O)Cl)C	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGJ53O	4-[5-(Difluoromethyl)-2-(4-sulfamoylphenyl)pyrazol-3-yl]benzamide	Investigative	10715523	C17H14F2N4O3S	392.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)C(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGJP79	2-(2-Chlorophenyl)-4-(2,4-difluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912186	C22H14ClF2NO2S2	461.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=C(C=C(C=C4)F)F	IC50 = 70000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGP49B	1-(2-(4-(4-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805177	C19H20F3NO2	351.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BGQ3F1	6-Chloro-7-(diisopropylamino)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53320186	C17H19ClF3NO3	377.8	CC(C)N(C1=C(C=C2C=C(C(OC2=C1)C(F)(F)F)C(=O)O)Cl)C(C)C	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH01BU	2-(3-Fluoro-5-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10787918	C18H14F4N2O3S	414.4	COC1=CC(=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH0I4Z	2-(Cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxylic acid	Investigative	45270280	C18H21N3O4S	375.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCCCC3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH0U8L	3-Benzo[b]thiophen-2-yl-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272282	C20H16O5S2	400.5	CC1(C(=C(C(=O)O1)C2=CC3=CC=CC=C3S2)C4=CC=C(C=C4)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH1Q5J	3-(2-Methoxyoxolan-2-yl)-1-(4-methylphenyl)-5-(4-methylsulfonylphenyl)pyrazole	Investigative	11361946	C22H24N2O4S	412.5	CC1=CC=C(C=C1)N2C(=CC(=N2)C3(CCCO3)OC)C4=CC=C(C=C4)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH1S9R	6-(4-Methanesulfonyl-phenyl)-5-phenyl-imidazo[2,1-b]thiazole	Investigative	15388847	C18H14N2O2S2	354.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N3C=CSC3=N2)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH20TX	5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-isothiazole	Investigative	15390773	C16H12FNO2S2	333.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SN=C2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH2TX0	Chembl4165597	Investigative	145953074	C20H18ClNO3S	387.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2CCCC3)C(=O)C4=CC=C(C=C4)Cl	IC50 = 152000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH2ZX0	2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carbaldehyde	Investigative	11792902	C17H13ClN2O3S	360.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C=O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH32JZ	(2R)-2-[4-[[(1R,2S)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid	Investigative	13148391	C15H20O3	248.32	C[C@H](C1=CC=C(C=C1)C[C@H]2CCC[C@@H]2O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH45VI	Proanthocyanidin A	Investigative	9808627	C31H28O12	592.5	COC1=C(C=C(C=C1O)[C@@H]2[C@@H](CC3=C(O2)C(=C(C=C3O)O)[C@@H]4[C@H]([C@H](OC5=CC(=CC(=C45)O)O)C6=CC=C(C=C6)O)O)O)O	IC50 = 138000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH48EW	3-(4-Methylsulfonylphenyl)-2-pyridin-3-ylpyridine	Investigative	44326499	C17H14N2O2S	310.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC=C2)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH4JS7	4-[3-(2-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732332	C23H20BrN3O2S	482.4	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=CC=C4Br)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH53MB	4-[5-(4-Fluorophenyl)-4-propyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10717364	C19H17F4N3O2S	427.4	CCCC1=C(N(N=C1C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH5B8T	3-[(3-Ethoxy)phenoxymethyl]-1-(4-methanesulfonylphenyl)-5-phenyl-1H-pyrazole	Investigative	11213050	C25H24N2O4S	448.5	CCOC1=CC(=CC=C1)OCC2=NN(C(=C2)C3=CC=CC=C3)C4=CC=C(C=C4)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH93CK	N-Methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline	Investigative	10620694	C18H16F3N3O2S	395.4	CNC1=CC=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BH9C3M	2-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}ethanol	Investigative	16125427	C18H16ClFN2O4S	410.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCO)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHB71Y	[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-ylmethyl]-dimethyl-amine	Investigative	10738921	C21H23FN2O2S	386.5	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)CN(C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHC31I	1,4-Benzodioxan-6-ylacetic acid	Investigative	87020	C10H10O4	194.18	C1COC2=C(O1)C=CC(=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHD36C	1-(4-Methylsulfonylphenyl)-2-(3-nitrophenyl)-4-(trifluoromethyl)imidazole	Investigative	10549551	C17H12F3N3O4S	411.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC=C3)[N+](=O)[O-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHD5S4	4-[5-(2-Dimethylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10740301	C18H17F3N4O2S	410.4	CN(C)C1=CC=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHF2U1	4-[5-(Difluoromethyl)-2-(4-sulfamoylphenyl)pyrazol-3-yl]benzoic Acid	Investigative	10668272	C17H13F2N3O4S	393.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHI91L	Chembl4173526	Investigative	145950583	C20H20ClNO2S	373.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2CCCC3)CC4=CC=C(C=C4)Cl	IC50 = 118000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHR90D	2-[1-(Trifluoromethyl)-2,2,2-trifluoroethoxy]-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine	Investigative	44293290	C16H10F9NO3S	467.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)C(F)(F)F)OC(C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHR9K0	2-(3-Chloro-4-methylsulfanyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10694708	C18H14ClF3N2O2S2	446.9	CSC1=C(C=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHS07O	Methyl 3-[(4-nitronaphthalen-1-yl)amino]benzoate	Investigative	70911877	C18H14N2O4	322.3	COC(=O)C1=CC(=CC=C1)NC2=CC=C(C3=CC=CC=C32)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BHUM01	1-(2-(4-(2-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805175	C19H20F3NO2	351.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI01HP	Chembl4169030	Investigative	145952805	C22H22ClNO2	367.9	CC1(CC2=C(C(=O)C1)C3=C(N2CC4=CC=C(C=C4)Cl)C=CC(=C3)OC)C	IC50 = 178000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI0QA9	1-(4-Fluorophenyl)-4-hydroxymethyl-5-methyl-2-(4-methylsulfonylphenyl)pyrrole	Investigative	10546382	C19H18FNO3S	359.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)CO	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI1WL8	N-(4-Fluorobenzyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	10180742	C19H15F4N3O2S	425.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NCC3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI4T2R	2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfonamide	Investigative	11089551	C16H19ClN2O3S	354.9	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)Cl)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI58AE	4-[2-(3-Chloro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	9947111	C19H19ClO3S	362.9	COC1=C(C=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI5D9R	3-(3-Chloro-4-methoxy-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran	Investigative	44316112	C22H17ClO4S	412.9	COC1=C(C=C(C=C1)C2=C(OC3=CC=CC=C32)C4=CC=C(C=C4)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI62UX	4-(4-Methanesulfonyl-phenyl)-5-phenyl-[1,3]dioxol-2-one	Investigative	44383441	C16H12O5S	316.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(OC(=O)O2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI6H9J	4-(3-Difluoromethyl-8-fluoro-7-methoxy-5H-isothiochromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide	Investigative	44327825	C18H14F3N3O3S2	441.5	COC1=C(C=C2C(=C1)CSC3=C2N(N=C3C(F)F)C4=CC=C(C=C4)S(=O)(=O)N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI76SD	1-Cyclohexyl-2-methyl-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10686987	C18H23NO2S	317.4	CC1=CC=C(N1C2CCCCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI8E6T	4-[5-Tert-butyl-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68291773	C21H24N2O2	336.4	CC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI93DJ	2-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	5080393	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI98CZ	4-[3-(Difluoromethyl)-5-(4-methylsulfonylphenyl)pyrazol-1-yl]benzenesulfonamide	Investigative	11796738	C17H15F2N3O4S2	427.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI9F1Z	4-[5-Tert-butyl-3-(4-ethoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548448	C22H26N2O3	366.5	CCOC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BI9N5A	N-Cyclohexyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	9930803	C18H20F3N3O2S	399.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCCCC3)C(F)(F)F	IC50 ~ 58400 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BID8F6	4-[2-(4-Fluoro-phenyl)-thiophen-3-yl]-N-methyl-benzenesulfonamide	Investigative	44307455	C17H14FNO2S2	347.4	CNS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BIL8C7	4-[2-(4-Methylpyridin-2-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10156720	C16H13F3N4O2S	382.4	CC1=CC(=NC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 84000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BIPY25	N-(3-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	Investigative	24853950	C13H10F3N3O	281.23	C1=CC(=C(N=C1)NC(=O)C2=CC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BIR86O	N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide	Investigative	15428927	C12H10N2O4S3	342.4	CS(=O)(=O)NC1=C(C=C2C(=C1)COC2=O)SC3=NC=CS3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BIV25M	2-Fluoro-1-methoxy-4-[2-(4-methylsulfonylphenyl)phenyl]benzene	Investigative	10546170	C20H17FO3S	356.4	COC1=C(C=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BIV78W	2,4,6-Trimethyl-3-[5-methyl-4-(4-sulfamoyl-phenyl)-isoxazol-3-yl]-benzenesulfonamide	Investigative	11487377	C19H21N3O5S2	435.5	CC1=CC(=C(C(=C1C2=NOC(=C2C3=CC=C(C=C3)S(=O)(=O)N)C)C)S(=O)(=O)N)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ0EQ8	6-Chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	11609224	C13H10ClF3O3	306.66	CC1=CC2=C(C=C(C(O2)C(F)(F)F)C(=O)O)C(=C1Cl)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ0MR4	N-(4-Fluorophenylsulfonyl)Isonicotinamide	Investigative	57392919	C12H9FN2O3S	280.28	C1=CC(=CC=C1F)S(=O)(=O)NC(=O)C2=CC=NC=C2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ15SV	2-(2-Oxochromen-7-yl)oxyethyl 1-(4-sulfamoylphenyl)-5-(3,4,5-trimethoxyphenyl)pyrazole-3-carboxylate	Investigative	137646026	C30H27N3O10S	621.6	COC1=CC(=CC(=C1OC)OC)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC5=C(C=C4)C=CC(=O)O5	IC50 = 53080 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ3V8O	3-(4-Fluorophenyl)-4-(4-methylsulfonylphenyl)thiophene	Investigative	10426884	C17H13FO2S2	332.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CSC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ4D1F	3-Methyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]isoxazole	Investigative	10947517	C17H14FNO3S	331.4	CC1=NOC(=C1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ4FV3	Hederasaponin B	Investigative	21626480	C59H96O25	1205.4	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ63CI	(S)-3-Ethyl-2-[3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-pentan-3-ol	Investigative	15887866	C20H24F3NO4S	431.5	CCC(CC)([C@H](C)OC1=C(C=C(C=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ7PW8	3-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-cyclopent-2-enone	Investigative	9796843	C17H15NO3S	313.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)C3=CN=CC=C3	IC50 = 73000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJ95GE	4-[5-Tert-butyl-3-(3-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548634	C20H21FN2O2	340.4	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)F)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJAG15	N-(4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805306	C19H24N2O4S	376.5	CS(=O)(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJEQ51	8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	11544925	C14H10F6O4	356.22	CCC1=CC(=CC2=C1OC(C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJNW95	3-(3,5-Dihydroxyphenyl)-7-hydroxycoumarin	Investigative	44406314	C15H10O5	270.24	C1=CC2=C(C=C1O)OC(=O)C(=C2)C3=CC(=CC(=C3)O)O	IC50 = 62300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BJXD87	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-phenyl-pyran-4-one	Investigative	9927909	C19H16O4S	340.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK0Y1E	3-(4-Methanesulfonyl-phenyl)-6-methoxy-2-p-tolyl-pyrazolo[1,5-b]pyridazine	Investigative	44395168	C21H19N3O3S	393.5	CC1=CC=C(C=C1)C2=NN3C(=C2C4=CC=C(C=C4)S(=O)(=O)C)C=CC(=N3)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK0ZF6	5-Methyl-3-(oxolan-2-yl)-4-phenyl-1,2-oxazole	Investigative	44194816	C14H15NO2	229.27	CC1=C(C(=NO1)C2CCCO2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK10GS	2-(4-Fluorophenyl)-3-(4-methylsulfonylphenyl)thiophene	Investigative	10336873	C17H13FO2S2	332.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK14YR	4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10069246	C18H16F3N3O2S	395.4	CC1=CC(=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)C	IC50 = 81800 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK1BN5	1-Fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-di(trifluoromethyl)-1-cyclopentenyl]benzene	Investigative	10095369	C20H15F7O2S	452.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC(C2)(C(F)(F)F)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK1Y5E	2-(5-Fluoro-2-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10810863	C18H14F4N2O2S	398.4	CC1=C(C=C(C=C1)F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK26WU	2-(3,5-Dichloro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone	Investigative	9821264	C18H14Cl2O3S	381.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)C3=CC(=CC(=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK5O4P	4-[4-Chloro-5-[3-fluoro-4-(3-hydroxypropoxy)phenyl]imidazol-1-yl]benzenesulfonamide	Investigative	16125422	C18H17ClFN3O4S	425.9	C1=CC(=CC=C1N2C=NC(=C2C3=CC(=C(C=C3)OCCCO)F)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK6Q1S	1-[(4-Chlorophenyl)carbonyl]-2-methyl-3-({N-[3-(nitrooxy)-propyl]carbamoyl}methyl)indol-5-yl aminosulfonate	Investigative	11853818	C21H21ClN4O8S	524.9	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OS(=O)(=O)N)CC(=O)NCCCO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BK97DT	Chembl4176892	Investigative	145971245	C21H20ClNO4S	417.9	CC1(CC2=C(C(=O)C1)C3=C(N2S(=O)(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)OC)C	IC50 = 167000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKB65X	N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide	Investigative	9929308	C14H14N2O4S3	370.5	CCC1=CSC(=N1)SC2=C(C=C3COC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKC9N8	4-[3-(4-Fluoro-phenyl)-5-(1-hydroxy-1-methyl-ethyl)-thiophen-2-yl]-benzenesulfonamide	Investigative	20658551	C19H18FNO3S2	391.5	CC(C)(C1=CC(=C(S1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=C(C=C3)F)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKD8E4	4-[2-(5-Methoxypyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10524898	C16H13F3N4O3S	398.4	COC1=CN=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKF1A6	4-[2-(6-Methylpyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10293242	C16H13F3N4O2S	382.4	CC1=NC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 89000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKGP69	2,2,2-Trifluoro-1-[4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]ethanone	Investigative	10621114	C18H9F7N2O	402.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)C(=O)C(F)(F)F)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKGY62	3-[4-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid	Investigative	122192742	C13H10F5NO2S	339.28	C1=CC(=CC(=C1)NC2=CC=C(C=C2)S(F)(F)(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKI52M	Methyl 4-[(4-sulfamoylphenyl)methylideneamino]benzoate	Investigative	44456559	C15H14N2O4S	318.3	COC(=O)C1=CC=C(C=C1)N=CC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 56730 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKL0Y3	4-[3-(2-Chloro-6-fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732338	C23H19ClFN3O2S	455.9	C1CC2=CC=CC=C2C3=NN(C(C31)C4=C(C=CC=C4Cl)F)C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 99840 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKL9M0	3-[(4-Chlorophenyl)Amino]Benzoic Acid	Investigative	53324830	C13H10ClNO2	247.67	C1=CC(=CC(=C1)NC2=CC=C(C=C2)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKM0H7	1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	11794411	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKP74N	2-Chloro-4-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-N,N-dimethylaniline	Investigative	10598294	C21H18ClF2NO2S	421.9	CN(C)C1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKR0Q3	4-[3-(4-Bromophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732346	C22H18BrN3O3S	484.4	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=CC=C(C=C5)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKU8A4	1-(3-Chloro-4-fluorophenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene	Investigative	10786954	C19H12ClF3O2S	396.8	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC(=C(C=C3)F)Cl)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKUB82	1-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-tetrazole	Investigative	44382878	C14H10F2N4O2S	336.32	CS(=O)(=O)C1=CC=C(C=C1)C2=NN=NN2C3=CC(=C(C=C3)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BKYM45	4-[2-(3-Chloro-5-methyl-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide	Investigative	22643554	C17H13ClF3N3O2S	415.8	CC1=CC(=CC(=C1)Cl)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL26BY	2-(2,4-Dichlorophenoxy)-N-[(E)-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]amino]acetamide	Investigative	137638629	C19H17Cl2N3O3S	438.3	CCC1=CC=C(C=C1)N\\2C(=O)CS/C2=N/NC(=O)COC3=C(C=C(C=C3)Cl)Cl	IC50 = 113120 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL35NB	2-(Methoxymethyl)-5-(3-oxo-3-phenyl-1-propenyl)-6-phenylpyridazine-3(2H)-one	Investigative	12130600	C21H18N2O3	346.4	COCN1C(=O)C=C(C(=N1)C2=CC=CC=C2)/C=C/C(=O)C3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL65IT	Chembl4239825	Investigative	145984214	C33H22Cl2N2O6	613.4	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OCC(=O)OCC4=NN(C(=C4)C5=CC(=C(C=C5)Cl)Cl)C6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL6A1C	4-[5-(4-Chlorophenyl)-3-(hydroxymethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	9947165	C16H14ClN3O3S	363.8	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)CO)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL6FB5	4-(4-Methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10519259	C16H15N3O2S	313.4	CC1=C(N(N=C1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BL71WB	2-(2-Oxochromen-7-yl)oxyethyl 5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137650099	C27H21N3O7S	531.5	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC5=C(C=C4)C=CC(=O)O5	IC50 = 51390 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLB8E6	4-[2-(3-Fluoro-4-methoxyphenyl)phenyl]benzenesulfonamide	Investigative	10808251	C19H16FNO3S	357.4	COC1=C(C=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 = 71600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLD4Q8	4-[5-(4-Cyanophenyl)-3-(difluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10714428	C17H12F2N4O2S	374.4	C1=CC(=CC=C1C#N)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLET41	3-(2-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one	Investigative	10406946	C19H16O6S	372.4	CC(=O)OC1=CC=CC=C1C2=C(COC2=O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLH03C	4-[5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548637	C23H19FN2O3	390.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLH4M6	2-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]propanoic acid	Investigative	134138298	C11H12N2O3S	252.29	CC1=CC(=NC2=C1C(=NS2)OC(C)C(=O)O)C	IC50 = 169824.37 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLH95D	4-(4-Fluorophenyl)-2-(1-methylpiperidin-4-yl)-5-(2-(1-(S)-Phenylethyl)amino-4-pyridinyl)thiazole	Investigative	10390073	C28H29FN4S	472.6	C[C@@H](C1=CC=CC=C1)NC2=NC=CC(=C2)C3=C(N=C(S3)C4CCN(CC4)C)C5=CC=C(C=C5)F	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLKV17	4-Methyl-N''-((4-oxo-4H-chromen-3-yl)methylene)benzenesulfonohydrazide	Investigative	9644405	C17H14N2O4S	342.4	CC1=CC=C(C=C1)S(=O)(=O)N/N=C/C2=COC3=CC=CC=C3C2=O	IC50 = 150450 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLO54Y	2-[[1-(4-Tert-butylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643683	C20H20N4OS	364.5	CC(C)(C)C1=CC=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 154260 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLPA02	N-Methyl-4-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline	Investigative	10500888	C18H16F3N3O2S	395.4	CNC1=CC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 53500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLQ9W0	2-(Benzenesulfonyl)-3-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706116	C18H15F3N2O4S	412.4	C1COC2=C(C=CC=C2O1)C3CC(=NN3S(=O)(=O)C4=CC=CC=C4)C(F)(F)F	IC50 = 100300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLU7K2	(2RS,4R)-2-(1,3-diphenyl-1H-pyrazol-4-yl)thiazolidine-4-carboxamide	Investigative	50908400	C19H18N4OS	350.4	C1[C@H](NC(S1)C2=CN(N=C2C3=CC=CC=C3)C4=CC=CC=C4)C(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLYX03	N-(3-Phenylsulfonyl-4-pyridinyl)methanesulfonamide	Investigative	11415723	C12H12N2O4S2	312.4	CS(=O)(=O)NC1=C(C=NC=C1)S(=O)(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BLZ23N	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-methyl-pyrazolo[1,5-b]pyridazine	Investigative	44395063	C20H16FN3O2S	381.4	CC1=NN2C(=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)S(=O)(=O)C)C=C1	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM0QB7	N-[3-(3-Ethylphenylamino)-4-pyridinyl]methanesulfonamide	Investigative	44475683	C14H17N3O2S	291.37	CCC1=CC(=CC=C1)NC2=C(C=CN=C2)NS(=O)(=O)C	IC50 = 60390 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM0U2Z	Sanggenon D	Investigative	9987332	C40H36O12	708.7	CC1=C[C@@H]([C@H]([C@@H](C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C5=C(C=C4O)OC6(C7=C(C=C(C=C7)O)OC6(C5=O)CC=C(C)C)O)O	IC50 = 59000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM28EO	N-Tosylisonicotinamide	Investigative	13986997	C13H12N2O3S	276.31	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CC=NC=C2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM2J4F	(R)-7-Tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	11693043	C15H14ClF3O3	334.72	CC(C)(C)C1=C(C=C2C=C([C@@H](OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 136000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM3O4A	6-Chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52942521	C17H11ClF3NO5S	433.8	C1=CC(=CC=C1C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl)S(=O)(=O)N	IC50 = 91400 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM56JK	[2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid sodium salt	Investigative	50901657	C29H31N2NaO5	510.6	CCN(CC1=C(C=CC(=C1)C2=CN=C(C=C2)OCC)C3=C(C=CC(=C3)CC(=O)[O-])OC)C(=O)C4CC4.[Na+]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM5G9C	2-(3,4-Difluorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10294501	C17H11F5N2O2S	402.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=C(C=C3)F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM5UB0	4-(4-(Methylsulfonyl)phenyl)-N-propyl-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45273829	C15H16F3N3O2S	359.4	CCCNC1=NC(=CC(=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM80DP	6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371400	C17H11F2N3O2S2	391.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N3C(=NC=N3)S2)C4=CC(=CC(=C4)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM81UJ	Phenylmethyl 2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate	Investigative	11856983	C26H21Cl2NO4	482.4	CC1=C(C2=CC(=C(C=C2N1C(=O)C3=CC=C(C=C3)Cl)Cl)OC)CC(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM8GR9	2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-phenoxy)-pyran-4-one	Investigative	11440998	C19H15NO7S	401.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM8J3Y	3-Oxaheneicosa-5,9,12,15,18-pentaenoic acid	Investigative	44584287	C20H30O3	318.4	CC/C=C/C/C=C/C/C=C/C/C=C/CC/C=C/COCC(=O)O	IC50 = 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM8Q7Y	1,2-Difluoro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)benzene	Investigative	10546567	C19H13F3O2S	362.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM8VQ5	1-(3,4-Difluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-carbaldehyde	Investigative	71714062	C19H15F2NO3S	375.4	CC1=C(C=C(N1C2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)S(=O)(=O)C)C=O	IC50 = 71400 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM9VZ1	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-hydroxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	136094858	C26H18ClN5O6S	564	C1=CC=C(C(=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BM9XZ5	4-Methoxy-N-(4-sulfamoylbenzylidene)aniline	Investigative	21862750	C14H14N2O3S	290.34	COC1=CC=C(C=C1)N=CC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 60740 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMDV04	6-[4-(Methylsulfonyl)phenyl]-5-[3-chloro-4-methoxyphenyl]spiro[2.4]hept-5-ene	Investigative	10157135	C21H21ClO3S	388.9	COC1=C(C=C(C=C1)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMJH34	1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)-3-(trifluoromethylsulfonyl)pyrrole	Investigative	10623882	C19H15F4NO4S2	461.5	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)S(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMO93Z	2-(Cyclopentylmethoxy)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine	Investigative	10453591	C18H19F3N2O3S	400.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)OCC3CCCC3)C(F)(F)F	IC50 = 69000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMV0A8	1h-Indole-3-acetic acid,1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2-phenylethyl ester	Investigative	10457034	C27H24ClNO4	461.9	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCCC4=CC=CC=C4	IC50 ~ 66000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMZ29A	4-(4-Fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole-2-carboxylic acid ethyl ester	Investigative	17816126	C19H16FNO4S2	405.5	CCOC(=O)C1=NC(=C(S1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BMZX93	4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	5181298	C23H20N2O3	372.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN08DI	1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazole-4-carboxylic acid ethyl ester	Investigative	10499452	C18H17N3O4S	371.4	CCOC(=O)C1=CN(C(=N1)C2=CN=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN1MA4	4-[3-(2-Methylphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732339	C23H21N3O3S	419.5	CC1=CC=CC=C1C2C3COC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 59360 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN1XG8	1-Isopropyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10660176	C15H19NO2S	277.4	CC1=CC=C(N1C(C)C)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN28GT	3-(4-Chlorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one	Investigative	11740421	C18H15ClO5S	378.8	CC1(C(=C(C(=O)O1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 = 105000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN34EW	1-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-3,5-dimethyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10598409	C20H19F3N2O3S	424.4	CC1=CC(=CC(=C1OC)C)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 91000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN4RJ5	2-(4-Chloro-phenyl)-4-(4-chloro-phenylsulfanylmethyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole	Investigative	10576988	C23H18Cl2N2O2S2	489.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CSC4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN69AX	2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carboxylic Acid	Investigative	11793960	C17H13ClN2O4S	376.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN6PA1	N-Acetyl-4-[2-(4-fluoro-phenyl)-thiophen-3-yl]-benzenesulfonamide	Investigative	44307454	C18H14FNO3S2	375.4	CC(=O)NS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN7I6K	N-(2-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16774693	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN7S1I	Pallidol	Investigative	484757	C28H22O6	454.5	C1=CC(=CC=C1[C@H]2[C@H]3[C@H]([C@@H](C4=C3C=C(C=C4O)O)C5=CC=C(C=C5)O)C6=C2C(=CC(=C6)O)O)O	IC50 = 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BN8FW2	[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]methanamine	Investigative	10594776	C17H16ClN3O2S	361.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CN	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BND25B	3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805174	C17H19N3O4	329.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=C(C=CC=N3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNF5G7	1-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-2,5-dimethyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10574332	C20H19F3N2O3S	424.4	CC1=CC(=C(C=C1OC)C)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNI29C	3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acid	Investigative	57563344	C20H18ClNO4	371.8	CC1=C(N(C2=C1C=C(C=C2)OC)C(=O)C3=CC=C(C=C3)Cl)CCC(=O)O	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNI39Q	2-[[1-(4-Fluorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643692	C16H11FN4OS	326.4	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC=C(C=C4)F	IC50 = 192150 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNJ25H	1h-Indole,1-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]-	Investigative	10693380	C20H16F3N3O2S	419.4	CN1C=C(C2=CC=CC=C21)C3=NC(=CN3C4=CC=C(C=C4)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNJ2Y7	Glucuronide conjugate OF 5-hydroxy rofecoxib	Investigative	71720245	C23H22O11S	506.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)C(=O)O)O)O)O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNJX08	4-[5-(4-Fluoro-phenyl)-pyrazol-1-yl]-benzenesulfonamide	Investigative	10852952	C15H12FN3O2S	317.3	C1=CC(=CC=C1C2=CC=NN2C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNK7A5	4-[(4-Hydroxy-3,5-dimethoxyphenyl)methylideneamino]benzenesulfonamide	Investigative	136152995	C15H16N2O5S	336.4	COC1=CC(=CC(=C1O)OC)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 155950 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNK8Z5	2-(2-Chlorophenyl)-4-(3-thienyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912244	C20H14ClNO2S3	432	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CSC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNKE93	(2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thiazolidine-4-carboxylic acid	Investigative	50908173	C20H19N3O2S	365.5	CC1=CC=C(C=C1)C2=NN(C=C2C3N[C@@H](CS3)C(=O)O)C4=CC=CC=C4	IC50 = 96220 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNL4O9	2-Ethyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	15429218	C18H23NO3S	333.4	CCC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3CCCCC3	IC50 = 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BNUY12	Salidroside	Investigative	159278	C14H20O7	300.3	C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O	IC50 = 72000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO03AS	5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-thiophen-2-yl-5H-furan-2-one	Investigative	44272115	C16H14O5S2	350.4	CC1(C(=C(C(=O)O1)C2=CC=CS2)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO0NT9	1-(4-Methanesulfonyl-phenyl)-2-m-tolyl-4-trifluoromethyl-1H-imidazole	Investigative	10110298	C18H15F3N2O2S	380.4	CC1=CC(=CC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 78000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO0S4T	4-[[3-Methoxy-4-hydroxybenzylidene]amino]benzenesulfonamide	Investigative	405561	C14H14N2O4S	306.34	COC1=C(C=CC(=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N)O	IC50 = 78200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO0VN7	4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-[1,2,3]thiadiazole	Investigative	9840638	C15H11FN2O2S2	334.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=NS2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO56NL	3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyrazolo[1,5-b]pyridazine	Investigative	11725371	C19H15N3O2S	349.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C3C=CC=NN3N=C2C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO76YP	3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-4-phenyl-isoxazole	Investigative	11382825	C19H18ClNO4	359.8	CC1=C(C(=NO1)C2=C(C(=C(C=C2OC)OC)Cl)OC)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO86UF	5-Chloro-3-[[1-(4-chlorophenyl)triazol-4-yl]methyl]-1,3-benzoxazol-2-one	Investigative	76313613	C16H10Cl2N4O2	361.2	C1=CC(=CC=C1N2C=C(N=N2)CN3C4=C(C=CC(=C4)Cl)OC3=O)Cl	IC50 = 111340 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO8B0Q	4-[3-(2-Methoxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732326	C24H23N3O3S	433.5	COC1=CC=CC=C1C2C3CCC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 96240 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BO9A0E	5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide	Investigative	44266508	C18H15ClN2O3S	374.8	CC1=[N+](C=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOA9E7	2-(2-Oxochromen-4-yl)oxyethyl 5-(4-nitrophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137654190	C27H20N4O9S	576.5	C1=CC=C2C(=C1)C(=CC(=O)O2)OCCOC(=O)C3=NN(C(=C3)C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 59060 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BODP53	4'-Fluorostilbene-3,5-diol	Investigative	11368202	C14H11FO2	230.23	C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)F	IC50 = 51300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOH89M	Clematichinenoside B	Investigative	49799272	C70H114O35	1515.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOK47J	6-Ethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	44395118	C21H18FN3O3S	411.5	CCOC1=NN2C(=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)S(=O)(=O)C)C=C1	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOLH18	1-(3,4-Dimethylphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene	Investigative	10595453	C21H18F2O2S	372.4	CC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BONV82	1-(3-Chloro-4-methylphenyl)-4,5-difluoro-2-[4-(methylsulfonyl)phenyl]benzene	Investigative	10524587	C20H15ClF2O2S	392.8	CC1=C(C=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOR4D8	2-(2-Chlorophenyl)-4-(3-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912115	C22H15ClFNO2S2	443.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CC(=CC=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BORW68	N-(3',4'-Dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide	Investigative	54728414	C21H14Cl2N2O4S	461.3	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl)O	IC50 = 118000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOVD92	Benzenesulfonamide,4-(3-methyl-5-phenyl-1h-pyrazol-1-yl)-	Investigative	10710312	C16H15N3O2S	313.4	CC1=NN(C(=C1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BOWT02	5-Hydroxyrofecoxib	Investigative	9973893	C17H14O5S	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP08GB	6-(2,4-Dichlorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene	Investigative	10620570	C20H18Cl2O2S	393.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CC3)C4=C(C=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP1SX3	4-(3-Hydroxy-4-methoxy-phenylazo)-benzenesulfonamide	Investigative	405490	C13H13N3O4S	307.33	COC1=C(C=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N)O	IC50 = 66410 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP2O9S	5-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-tetrazole	Investigative	44382879	C14H10F2N4O2S	336.32	CS(=O)(=O)C1=CC=C(C=C1)N2C(=NN=N2)C3=CC(=C(C=C3)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP2SW8	4-(4-Fluoro-5-phenyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10734248	C15H12FN3O2S	317.3	C1=CC=C(C=C1)C2=C(C=NN2C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 = 56500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP4I5R	N-(4-Methylbenzyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45270336	C20H18F3N3O2S	421.4	CC1=CC=C(C=C1)CNC2=NC(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BP58ZF	4-[2-(4-Ethoxy-phenyl)-6-methanesulfonyl-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide	Investigative	44395152	C21H20N4O5S2	472.5	CCOC1=CC=C(C=C1)C2=NN3C(=C2C4=CC=C(C=C4)S(=O)(=O)N)C=CC(=N3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPAI72	6-[4-(Methylsulfonyl)phenyl]-5-[3,5-dichloro-4-methoxyphenyl]spiro[2.4]hept-5-ene	Investigative	9823594	C21H20Cl2O3S	423.4	COC1=C(C=C(C=C1Cl)C2=C(CC3(C2)CC3)C4=CC=C(C=C4)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPD6L0	N-[6-(2,6-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	10714139	C16H13F2NO3S2	369.4	CS(=O)(=O)NC1=C(C=C2C(=C1)CCC2=O)SC3=C(C=CC=C3F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPD8E1	5-(4-Methanesulfonyl-phenyl)-3-methyl-6-phenyl-imidazo[2,1-b]thiazole	Investigative	15388843	C19H16N2O2S2	368.5	CC1=CSC2=NC(=C(N12)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPF3Z1	Cyclopentyl-{4-[2-(4-fluoro-phenyl)-5-(4-methyl-piperazin-1-yl)-imidazo[4,5-b]pyridin-1-yl]-pyrimidin-2-yl}-amine	Investigative	9826083	C26H29FN8	472.6	CN1CCN(CC1)C2=NC3=C(C=C2)N(C(=N3)C4=CC=C(C=C4)F)C5=NC(=NC=C5)NC6CCCC6	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPFK78	4-[2-(4-Fluoro-phenyl)-thiophen-3-yl]-benzoic acid	Investigative	44307510	C17H11FO2S	298.3	C1=CC(=CC=C1C2=C(SC=C2)C3=CC=C(C=C3)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPN7B8	4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-phenoxypyrimidine	Investigative	45273799	C23H17FN2O3S	420.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)OC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPO7C9	1-(2-(4-(4-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805053	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPR3V2	N2-Cyclohexyl-6-(4-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine	Investigative	45271990	C17H22N4O2S	346.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NC3CCCCC3)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPR50I	2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetic acid	Investigative	46229713	C20H18FNO4S	387.4	CC1=C(C=C(N1C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)CC(=O)O	IC50 = 125000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPTS73	4-[3-(3-Nitrophenyl)-5-propan-2-yl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	129012346	C19H19N3O4	353.4	CC(C)C1=NN(C(C1)C2=CC(=CC=C2)[N+](=O)[O-])C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPU19E	Kazinol B	Investigative	480869	C25H28O4	392.5	CC(=CCC1=C(C=C2C=CC(OC2=C1O)(C)C)[C@@H]3CCC4=C(O3)C=C(C=C4)O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPU4K2	2-(4-(Methylsulfonyl)phenyl)-3-p-tolylthiazolidin-4-one	Investigative	44443328	C17H17NO3S2	347.5	CC1=CC=C(C=C1)N2C(SCC2=O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 53900 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BPZ0Y6	1-(2-(4-(4-Fluorophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	18678268	C18H20FNO2	301.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ0H7R	2-(5-Bromopyridin-3-yl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one	Investigative	10500696	C17H14BrNO3S	392.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)C3=CC(=CN=C3)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ19XT	8-Chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9922118	C12H8ClF3O3	292.64	CC1=CC2=C(C(=C1)Cl)OC(C(=C2)C(=O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ1E6N	1-(3,4-Difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10641380	C18H15F2NO2S	347.4	CC1=CC=C(N1C2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ21PR	4-[2-(3-Fluoro-5-methyl-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide	Investigative	10200928	C17H13F4N3O2S	399.4	CC1=CC(=CC(=C1)F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 82000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ2B5D	(2S)-2-[4-[[(1S,2R)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid	Investigative	13148392	C15H20O3	248.32	C[C@@H](C1=CC=C(C=C1)C[C@@H]2CCC[C@H]2O)C(=O)O	IC50 = 51000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ2X6O	5-[4-(Methylsulfonyl)phenyl]-6-(4-fluorophenyl)-1,3-benzodioxole	Investigative	10761664	C20H15FO4S	370.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2C4=CC=C(C=C4)F)OCO3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ34IB	(NZ)-N-[[1-(3,4-difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]methylidene]hydroxylamine	Investigative	73356534	C19H16F2N2O3S	390.4	CC1=C(C=C(N1C2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)S(=O)(=O)C)/C=N\\O	IC50 = 161000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ3R6G	N'-[4-[4-[(Z)-[(Z)-[4-(4-Bromophenyl)-3-(4-methylphenyl)-1,3-thiazol-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonyl-N,N-dimethylmethanimidamide	Investigative	24850953	C35H30BrN7O2S2	724.7	CC1=CC=C(C=C1)N\\2C(=CS/C2=N\\N=C/C3=CN(N=C3C4=CC=CC=C4)C5=CC=C(C=C5)S(=O)(=O)/N=C/N(C)C)C6=CC=C(C=C6)Br	IC50 = 96250 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ61WT	1-(2-(4-(4-Bromophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805179	C18H20BrNO2	362.3	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ62NU	4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	6426663	C16H12F3N3O2S	367.3	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 55100 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ6W0S	(2S)-6-Bromo-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	118222242; 118716570	C12H8BrF3O3	337.09	CC1=CC(=CC2=C1O[C@@H](C(=C2)C(=O)O)C(F)(F)F)Br	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ76ZJ	4-[3-(3-Methoxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732327	C24H23N3O3S	433.5	COC1=CC=CC(=C1)C2C3CCC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 85460 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQ7T1O	Cussonoside B	Investigative	169187	C48H78O17	927.1	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQB0D7	3-(4-Tert-butylanilino)benzoic acid	Investigative	53316889	C17H19NO2	269.34	CC(C)(C)C1=CC=C(C=C1)NC2=CC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQC3D5	4-[3-(4-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732334	C23H20BrN3O2S	482.4	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=C(C=C4)Br)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQC3N2	2-[[1-(3,4-Dimethylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643682	C18H16N4OS	336.4	CC1=C(C=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3)C	IC50 = 140450 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQC4S8	2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone	Investigative	10543451	C18H20O3S	316.4	CC(C)(C)C#CC1=C(CCC1=O)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQE60V	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(4-phenylpiperidin-1-yl)prop-2-en-1-one	Investigative	71652683	C31H33NO4	483.6	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)N3CCC(CC3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQIU39	6,7-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9966560	C11H5Cl2F3O3	313.05	C1=C2C=C(C(OC2=CC(=C1Cl)Cl)C(F)(F)F)C(=O)O	IC50 = 94500 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQS7L0	1-(4-Methanesulfonyl-phenyl)-2-phenyl-1H-imidazole	Investigative	10804032	C16H14N2O2S	298.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=CN=C2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQU0N4	4-[4-Methoxy-5-phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10524857	C17H14F3N3O3S	397.4	COC1=C(N(N=C1C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQU61E	3-N,5-N-Bis-(4-methylphenyl)sulfonylpyridine-3,5-dicarboxamide	Investigative	57396409	C21H19N3O6S2	473.5	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CC(=CN=C2)C(=O)NS(=O)(=O)C3=CC=C(C=C3)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BQUN41	5-Chloro-3-(4-methanesulfonyl-phenyl)-5''-methyl-[2,3'']bipyridinyl	Investigative	44326894	C18H15ClN2O2S	358.8	CC1=CC(=CN=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR02ZB	N-(Cyclohexylmethyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45271088	C19H22F3N3O2S	413.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NC(=N2)NCC3CCCCC3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR0CT9	N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]trifluoromethanesulfonamide	Investigative	11463338	C12H7Cl2F3N2O3S	387.2	C1=CN=CC(=C1NS(=O)(=O)C(F)(F)F)OC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR13WD	N-[4-[5-(4-Fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]methanesulfonamide	Investigative	10524951	C17H13F4N3O2S	399.4	CS(=O)(=O)NC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR14AI	4-[2-(4-Methylpyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10714907	C16H13F3N4O2S	382.4	CC1=C(C=NC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR4VB0	1-(4-Fluorophenyl)-4-formyl-5-methyl-2-(4-methylsulfonylphenyl)pyrrole	Investigative	10832170	C19H16FNO3S	357.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C=O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR53MX	2-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-5-methyl-1H-pyrrole	Investigative	10830212	C18H16FNO2S	329.4	CC1=CC=C(N1C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR6E4B	Epicatechin-(4beta-8)-epiafzelechin	Investigative	14015948	C30H26O11	562.5	C1[C@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC=C(C=C6)O)O	IC50 = 78000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR6XI5	3-(4-Bromo-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	44272072	C18H15BrO5S	423.3	CC1(C(=C(C(=O)O1)C2=CC=C(C=C2)Br)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BR9QD7	2-(3,5-Difluoro-phenoxy)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone	Investigative	10594921	C18H14F2O4S	364.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)OC3=CC(=CC(=C3)F)F	IC50 = 94000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRAF14	Loxoprofen	Investigative	3965	C15H18O3	246.3	CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRDJ41	2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carbonitrile	Investigative	10784589	C17H12ClN3O2S	357.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRF72L	2-[[1-(3-Chlorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643688	C16H11ClN4OS	342.8	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC(=CC=C4)Cl	IC50 = 88260 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRF7K2	2-[(1-Pyridin-3-yltriazol-4-yl)methylsulfanyl]-1,3-benzoxazole	Investigative	90643685	C15H11N5OS	309.3	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CN=CC=C4	IC50 = 96560 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRG31Y	2-(4-Methylsulfinylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10574542	C18H15F3N2O3S2	428.5	CS(=O)C1=CC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRH36X	4-[5-(3,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68292453	C25H24N2O5	432.5	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC(=C(C=C4)OC)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRI1Q4	3-Fluoro-5-[[1-(4-methylsulfonylphenyl)-5-phenylpyrazol-3-yl]methoxy]benzonitrile	Investigative	11430770	C24H18FN3O3S	447.5	CS(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)COC3=CC(=CC(=C3)C#N)F)C4=CC=CC=C4	IC50 = 99560 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRI78N	4-[5-Tert-butyl-3-(3,4-dichlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548446	C20H20Cl2N2O2	391.3	CC(C)(C)C1=NN(C(C1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRJI73	2-(2-Chlorophenyl)-4-(2,5-difluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	44271141	C22H14ClF2NO2S2	461.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=C(C=CC(=C4)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRJP30	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805049	C17H20N2O2	284.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRWK90	(R)-8-Propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52946285	C15H12F6O4	370.24	CCCC1=CC(=CC2=C1O[C@H](C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BRXE51	4-(4-Cyano-5-p-tolyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10664738	C17H14N4O2S	338.4	CC1=CC=C(C=C1)C2=C(C=NN2C3=CC=C(C=C3)S(=O)(=O)N)C#N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS0N3F	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dipentylprop-2-enamide	Investigative	71652366	C30H41NO4	479.6	CCCCCN(CCCCC)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS3C5Y	2-(4-Chlorophenyl)-N,N-diethyl-1-(4-methylsulfonylphenyl)imidazole-4-carboxamide	Investigative	10526696	C21H22ClN3O3S	431.9	CCN(CC)C(=O)C1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS62OW	5-(4-Fluoro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid amide	Investigative	12080914	C16H13FN4O3S	360.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS6TJ5	3-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]quinoline	Investigative	10693269	C20H14F3N3O2S	417.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC4=CC=CC=C4N=C3)C(F)(F)F	IC50 = 82000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS74ZD	1-Butyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10541610	C16H21NO2S	291.4	CCCCN1C(=CC=C1C2=CC=C(C=C2)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS8I2Y	3-(4-Chloro-2-fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one	Investigative	11417961	C19H14ClFO4S	392.8	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=C(C=C(C=C3)Cl)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS8RX7	2-Methyl-4-cyclopentyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	15429221	C16H19NO3S	305.4	CC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3CCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS93WZ	2-Phenethyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912151	C24H20FNO2S2	437.6	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)CCC3=CC=CC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS95HZ	Kizuta Saponin K12	Investigative	49799268	C59H96O26	1221.4	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS96VJ	2-Methyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	10172237	C17H14FNO2S2	347.4	CC1=NC(=C(S1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS9AN7	4-[5-Tert-butyl-3-(4-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548270	C20H22N2O3	338.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)O)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS9D5Y	5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,2'']bipyridinyl	Investigative	10269056	C17H13ClN2O2S	344.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CC=CC=N3	IC50 = 63000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BS9RZ0	3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-2-methyl-1H-indole	Investigative	22034364	C16H14FNO2S2	335.4	CC1=C(C2=C(N1)C=C(C=C2)S(=O)(=O)C)SC3=CC=C(C=C3)F	IC50 = 55700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSAX43	2-Benzo[1,3]dioxol-4-yl-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10716484	C18H13F3N2O4S	410.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=C4C(=CC=C3)OCO4)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSD30W	3-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate	Investigative	16125489	C19H17ClFN3O6S	469.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCCO[N+](=O)[O-])F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSG98J	1-(2-(4-(3-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805052	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=CC(=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSHA29	4-(3-Phenyl-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl)benzenesulfonamide	Investigative	118732322	C23H21N3O2S	403.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC=CC=C4)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSJ98I	(R)-8-Methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52942694	C13H8F6O4	342.19	CC1=CC(=CC2=C1O[C@H](C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 = 62700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSK4P0	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-bis(2-methylpropyl)prop-2-enamide	Investigative	71652365	C28H37NO4	451.6	CC(C)CN(CC(C)C)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSKT32	N-Methyl-4-(4-(methylsulfonyl)phenyl)-N-p-tolyl-6-(trifluoromethyl)pyrimidin-2-amine	Investigative	45269433	C20H18F3N3O2S	421.4	CC1=CC=C(C=C1)N(C)C2=NC(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 74175 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSM7W6	2-(4-Fluoro-phenyl)-6-methanesulfonyl-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	11155025	C20H16FN3O4S2	445.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C3C=CC(=NN3N=C2C4=CC=C(C=C4)F)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSN3U4	Huzhangoside D	Investigative	49799270	C64H104O30	1353.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSN7T6	2-(6-Chloro-9H-carbazol-2-yl)-propionic acid 2-nitrooxy-propyl ester	Investigative	44587479	C18H17ClN2O5	376.8	CC(COC(=O)C(C)C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)O[N+](=O)[O-]	IC50 = 123000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSP72N	2-Methyl-1-(4-methylphenyl)-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10663833	C19H19NO2S	325.4	CC1=CC=C(C=C1)N2C(=CC=C2C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSQM70	N-(Phenylsulfonyl)nicotinamide	Investigative	1500233	C12H10N2O3S	262.29	C1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSV8D1	3-{4-[1-(4-(Aminosulfonyl)phenyl)-4-chloro-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate	Investigative	16125424	C18H16ClFN4O6S	470.9	C1=CC(=CC=C1N2C=NC(=C2C3=CC(=C(C=C3)OCCCO[N+](=O)[O-])F)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSX5I3	3-[(3-Chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10624176	C25H21ClFNO3S	470	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)COC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BSYB46	4-[3-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazol-1-yl]benzenesulfonamide	Investigative	10181405	C17H11F6N3O2S	435.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT18QN	2-Chloro-1-methoxy-4-[2-(4-methylsulfonylphenyl)phenyl]benzene	Investigative	10667040	C20H17ClO3S	372.9	COC1=C(C=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)S(=O)(=O)C)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT1PH7	1-(2-(4-(3-Nitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49804918	C18H20N2O4	328.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT38XC	4-[3-(2-Chlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732343	C22H18ClN3O3S	439.9	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=CC=CC=C5Cl	IC50 = 86760 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT3EN4	4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-phenoxy-5H-furan-2-one	Investigative	9950669	C19H18O5S	358.4	CC1(C(=C(C(=O)O1)OC2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT60VC	2-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-pyrrole	Investigative	10425834	C17H14FNO2S	315.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT78QO	4-(4-Hydroxy-5-phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10738721	C16H12F3N3O3S	383.3	C1=CC=C(C=C1)C2=C(C(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT8F9H	5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	9905875	C17H22O5S	338.4	CC[C@]1(C(=C(C(=O)O1)OC(C)C)C2=CC=C(C=C2)S(=O)(=O)C)C	IC50 ~ 86000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BT8LR3	4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10621593	C16H14ClN3O4S2	411.9	CS(=O)(=O)C1=C(N(N=C1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=C(C=C3)Cl	IC50 = 52000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTA4U0	Coniferin	Investigative	5280372	C16H22O8	342.34	COC1=C(C=CC(=C1)/C=C/CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O	IC50 = 75000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTAU80	2-(2,2,2-Trifluoroethoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine	Investigative	44293185	C15H11F6NO3S	399.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)C(F)(F)F)OCC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTC6L8	2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid amide	Investigative	9839884	C17H17NO3S	315.4	CCC1=CC(=CC(=C1)C(=O)C2=CC=CC=C2)/C=C/S(=O)(=O)N	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTHX69	2-(5-Chloro-pyridin-3-yl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone	Investigative	10665362	C17H14ClNO3S	347.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)CC2)C3=CC(=CN=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTLB26	6-(4-Methanesulfonyl-phenyl)-2-methyl-5-phenyl-imidazo[2,1-b]thiazole	Investigative	23225437	C19H16N2O2S2	368.5	CC1=CN2C(=C(N=C2S1)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTS40F	6,8-Dimethoxy-3-(3'',5''-dimethoxyphenyl)coumarin	Investigative	44406245	C19H18O6	342.3	COC1=CC(=CC(=C1)C2=CC3=CC(=CC(=C3OC2=O)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BTU20J	4-[5-Pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10021928	C15H11F3N4O2S	368.3	C1=CC(=CN=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU15YB	1-(4-Methylsulfonylphenyl)-2-thiophen-3-yl-4-(trifluoromethyl)imidazole	Investigative	10619274	C15H11F3N2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CSC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU1BZ7	5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371457	C18H15N3O2S2	369.5	CC1=NN2C(=C(SC2=N1)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU2IP4	1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzene	Investigative	10447425	C18H18O2S	298.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU39MO	4-[2-(2-Chlorophenyl)-4-(3-fluoro-4-methoxyphenyl)-5-thiazolyl]benzenesulfonamide	Investigative	22911970	C22H16ClFN2O3S2	475	COC1=C(C=C(C=C1)C2=C(SC(=N2)C3=CC=CC=C3Cl)C4=CC=C(C=C4)S(=O)(=O)N)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU39QM	2-(2-Oxochromen-7-yl)oxyethyl 5-(3-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137639679	C27H20ClN3O7S	566	C1=CC(=CC(=C1)Cl)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC5=C(C=C4)C=CC(=O)O5	IC50 = 56520 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU4PH0	2-(2-Thienyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	10273329	C20H14FNO2S3	415.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CS3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU5A9C	Chembl4172740	Investigative	145950339	C19H16ClNO5S2	437.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2C(=O)CCC3)S(=O)(=O)C4=CC=C(C=C4)Cl	IC50 = 145000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU6CV0	4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10623232	C18H15ClF3N3O3S	445.8	CC1=CC(=CC(=C1OC)Cl)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU91BW	1-(4-Chlorophenyl)-2-(4-methylsulfonylphenyl)benzene	Investigative	10641092	C19H15ClO2S	342.8	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU91HB	4-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine	Investigative	10570970	C16H12F3N3O2S	367.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=NC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BU9Y8E	1-(2-(4-(4-Chlorophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805178	C18H20ClNO2	317.8	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUA5X8	Sodium;(4R,5S)-6-hydroxy-5-(4-methylsulfonylphenyl)-4-phenylhexanoate	Investigative	44323818	C19H21NaO5S	384.4	CS(=O)(=O)C1=CC=C(C=C1)[C@@H](CO)[C@@H](CCC(=O)[O-])C2=CC=CC=C2.[Na+]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUC86H	US9271961, Bmt 3-224	Investigative	124222778	C16H13NO5	299.28	CC(=O)C1=CC(=C(C=C1)C(=O)O)NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUCX40	3-(4-Acetylanilino)benzoic acid	Investigative	11184397	C15H13NO3	255.27	CC(=O)C1=CC=C(C=C1)NC2=CC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUEZ34	3-Cyclohexyl-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	11439406	C19H22O4S	346.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUM6H5	3-Cyclohexyl-4-(4-sulfamoylphenyl)-4-oxazoline-2-one	Investigative	10381453	C15H18N2O4S	322.4	C1CCC(CC1)N2C(=COC2=O)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUN3L1	4-[3-(3-Hydroxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide	Investigative	118732335	C23H21N3O3S	419.5	C1CC2=CC=CC=C2C3=NN(C(C31)C4=CC(=CC=C4)O)C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 86230 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BUPM93	N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide	Investigative	127049134	C26H18ClN5O5S	548	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N/N=C/C4=C(C5=CC=CC=C5OC4=O)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV02FI	[1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]methyl Acetate	Investigative	9909016	C21H20FNO4S	401.5	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)COC(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV02QD	4-[5-(2-Methoxyphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10272113	C17H14F3N3O3S	397.4	COC1=CC=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV0N7C	[1-[4-[5-Chloro-3-(4-methylsulfonylphenyl)imidazol-4-yl]-2-fluorophenoxy]-3-nitrooxypropan-2-yl] nitrate	Investigative	16125491	C19H16ClFN4O9S	530.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCC(CO[N+](=O)[O-])O[N+](=O)[O-])F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV1LP5	1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)-3-(2,2,2-trifluoroethyl)pyrrole	Investigative	10621562	C20H17F4NO2S	411.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)CC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV1S2I	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-prop-2-ynylprop-2-enamide	Investigative	71495889	C23H23NO4	377.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)NCC#C	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV2EC8	Sodium;2-[2-(4-fluorophenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56672144	C21H20FNaO3	362.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)F)C(=O)[O-].[Na+]	IC50 = 174000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV2GH9	4-[3-(2-Methoxyphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732340	C23H21N3O4S	435.5	COC1=CC=CC=C1C2C3COC4=CC=CC=C4C3=NN2C5=CC=C(C=C5)S(=O)(=O)N	IC50 = 68490 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV3H1X	1-(2-(4-(3-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805176	C19H20F3NO2	351.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV4MZ3	2-(4-Chlorophenyl)-4-(methylsulfanylmethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10620563	C18H17ClN2O2S2	392.9	CSCC1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV4OC8	Chembl4242033	Investigative	145983279	C33H23ClN2O6	579	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OCC(=O)OCC4=NN(C(=C4)C5=CC=C(C=C5)Cl)C6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV54NF	4-((3,4-Dimethoxyphenyl)diazenyl)benzenesulfonamide	Investigative	405488	C14H15N3O4S	321.35	COC1=C(C=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N)OC	IC50 = 61730 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV7AQ9	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-octylprop-2-enamide	Investigative	71652198	C28H37NO4	451.6	CCCCCCCCNC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV8H2T	1,1-Diphenyl-2-(4-mesylphenyl)-1-hexene	Investigative	10408088	C25H26O2S	390.5	CCCCC(=C(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BV8OD4	{2,6-Dichloro-4-[1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-dimethyl-amine	Investigative	10576610	C19H16Cl2F3N3O2S	478.3	CN(C)C1=C(C=C(C=C1Cl)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVA4F8	3-[(4-Bromophenyl)Amino]Benzoic Acid	Investigative	53316888	C13H10BrNO2	292.13	C1=CC(=CC(=C1)NC2=CC=C(C=C2)Br)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVD52G	2-[(2Z)-3,7-Dimethylocta-2,6-dienyl]-6-methylcyclohexa-2,5-diene-1,4-dione	Investigative	44584256	C17H22O2	258.35	CC1=CC(=O)C=C(C1=O)C/C=C(/C)\\CCC=C(C)C	IC50 = 64000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVDB16	3-Cyclohexyloxy-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one	Investigative	9925288	C19H24O5S	364.5	CC1(C(=C(C(=O)O1)OC2CCCCC2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 58000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVF76N	4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)isothiazole	Investigative	18400199	C16H12FNO2S2	333.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=NS2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVF7X4	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(3-methylpiperidin-1-yl)prop-2-en-1-one	Investigative	71652529	C26H31NO4	421.5	CC1CCCN(C1)C(=O)/C=C/C2=C(C=C(C=C2OC)OC)/C=C/C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVF8E1	N-(4-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide	Investigative	24853948	C13H10F3N3O	281.23	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=NC=CC(=C2)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVF9K6	6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371423	C17H12FN3O2S2	373.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N3C(=NC=N3)S2)C4=CC(=CC=C4)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVG8O9	3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone	Investigative	127923	C17H12F2O4S	350.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC(=C(C=C3)F)F	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVHZ43	1,3-Dichloro-5-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-2-methoxybenzene	Investigative	10789363	C20H14Cl2F2O3S	443.3	COC1=C(C=C(C=C1Cl)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVN86O	(2R,3S,4S,5S,6R)-6-[[5-[5-Chloro-3-(4-methylsulfonylphenyl)pyridin-2-yl]pyridin-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid	Investigative	71718474	C24H23ClN2O9S	551	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CN=C(C=C3)CO[C@H]4[C@H]([C@H]([C@@H]([C@@H](O4)C(=O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVS5B9	2-[[1-(4-Chlorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643689	C16H11ClN4OS	342.8	C1=CC=C2C(=C1)N=C(O2)SCC3=CN(N=N3)C4=CC=C(C=C4)Cl	IC50 = 80820 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVUM70	4-[3-(4-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68293323	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BVW81C	2-(2,4-Difluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine	Investigative	45267733	C24H17F3N2O2S	454.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)CC4=C(C=C(C=C4)F)F	IC50 ~ 52124 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW0SJ1	1-(4-Benzenesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10762141	C22H16FNO2S	377.4	C1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)N3C=CC=C3C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW28IU	3-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid	Investigative	10666215	C16H12N2O6S	360.3	C1=CC(=CC(=C1)N2C(=COC2=O)C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW63BO	4-(4-Fluorophenyl)-5-(4-methylsulfonylphenyl)-2-phenylthiazole	Investigative	22911939	C22H16FNO2S2	409.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW7KQ4	2-(1-(4-Bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl 4-chlorobenzoate	Investigative	9936231	C26H23BrClNO3	512.799	CC1=C(C2=C(N1CC3=CC=C(C=C3)Br)C=CC(=C2)OC)CCOC(=O)C4=CC=C(C=C4)Cl	IC50 ~ 66000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW7RK9	3-[[4-(2,3-Dichlorophenyl)piperazin-1-yl]methyl]-6,6-dimethyl-4-phenyl-4,5-dihydrooxazine	Investigative	122182710	C23H27Cl2N3O	432.4	CC1(CC(C(=NO1)CN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl)C4=CC=CC=C4)C	IC50 = 54900 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW91GF	2-[[1-(2-Methylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643693	C17H14N4OS	322.4	CC1=CC=CC=C1N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 132320 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW9AO8	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(3,4,5-trimethoxyphenyl)prop-2-enamide	Investigative	71652201	C29H31NO7	505.6	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)NC3=CC(=C(C(=C3)OC)OC)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW9P5R	3-Benzyl-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one	Investigative	10108931	C20H20O4S	356.4	CC1(C(=C(C(=O)O1)CC2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 90000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BW9Y2D	Clematiunicinoside E	Investigative	11994185	C76H124O39	1661.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWC65H	N-Cyclohexyl-4-methyl-6-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine	Investigative	45267716	C18H23N3O2S	345.5	CC1=CC(=NC(=N1)NC2CCCCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWET26	2-Tert-Butyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22911749	C20H20FNO2S2	389.5	CC(C)(C)C1=NC(=C(S1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWGN50	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dimethylprop-2-enamide	Investigative	71652364	C22H25NO4	367.4	CN(C)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWK19Z	Chembl4177185	Investigative	145971276	C19H18ClNO4S2	423.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2CCCC3)S(=O)(=O)C4=CC=C(C=C4)Cl	IC50 = 120000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWK64U	Cussonoside A	Investigative	171596	C48H78O18	943.1	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWK82I	2-(2-Chlorophenyl)-4-(2-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912091	C22H15ClFNO2S2	443.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CC=CC=C4F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWKQ39	(3R,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihydro-furan-2-one	Investigative	44323830	C17H16O4S	316.4	CS(=O)(=O)C1=CC=C(C=C1)[C@H]2COC(=O)[C@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWM30K	3-(5-Chlorofuran-2-yl)-5-phenyl-1,2-oxazole-4-carboxylic acid	Investigative	57780772	C14H8ClNO4	289.67	C1=CC=C(C=C1)C2=C(C(=NO2)C3=CC=C(O3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWO50X	(4S,4Ar,8aR)-3-(carbazol-9-ylmethyl)-4-phenyl-4a,5,6,7,8,8a-hexahydro-4H-1,2-benzoxazine	Investigative	122182711	C27H26N2O	394.5	C1CC[C@@H]2[C@H](C1)[C@H](C(=NO2)CN3C4=CC=CC=C4C5=CC=CC=C53)C6=CC=CC=C6	IC50 = 59900 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWOH67	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)naphthalene	Investigative	10762072	C23H17FO2S	376.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=CC=CC=C3C=C2C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWSV47	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoic acid	Investigative	71652197	C20H20O5	340.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWT9X1	6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371407	C17H13N3O2S2	355.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC3=NC=NN23)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BWX01Y	4-(2-Thiophen-2-yl-4-trifluoromethyl-imidazol-1-yl)-benzenesulfonamide	Investigative	10619336	C14H10F3N3O2S2	373.4	C1=CSC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 55000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX0R9B	Osthenol	Investigative	5320318	C14H14O3	230.26	CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)O)C	IC50 = 64000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX17MS	N-[(E)-(3-Benzyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]-2-(2,4-dichlorophenoxy)acetamide	Investigative	137661149	C18H15Cl2N3O3S	424.3	C1C(=O)N(/C(=N\\NC(=O)COC2=C(C=C(C=C2)Cl)Cl)/S1)CC3=CC=CC=C3	IC50 = 95440 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX19PQ	N-[6-(4-Methyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide	Investigative	44286188	C14H14N2O3S3	354.5	CC1=CSC(=N1)SC2=C(C=C3CCC(=O)C3=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX2O4T	4-[(4-Chlorophenoxy)methyl]-2-(4-chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10600544	C23H18Cl2N2O3S	473.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)COC4=CC=C(C=C4)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX38TG	3-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propan-1-ol	Investigative	16125428	C19H18ClFN2O4S	424.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCCO)F)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX3B6E	3-[[1-(4-Fluorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one	Investigative	76335317	C17H13FN4O2	324.31	CC1=CC2=C(C=C1)N(C(=O)O2)CC3=CN(N=N3)C4=CC=C(C=C4)F	IC50 = 174720 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX4I2F	3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid	Investigative	51346826	C14H10F3NO2	281.23	C1=CC(=CC(=C1)NC2=CC=C(C=C2)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX5R7G	2-Methyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline	Investigative	10947004	C17H17NO3S	315.4	CN1CC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX67AF	2-(2-Oxochromen-7-yl)oxyethyl 5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137652535	C28H23N3O8S	561.6	COC1=CC=CC(=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC5=C(C=C4)C=CC(=O)O5	IC50 = 52670 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX71OF	3-(4-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one	Investigative	10090654	C19H16O6S	372.4	CC(=O)OC1=CC=C(C=C1)C2=C(COC2=O)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX7T9L	4-[3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide	Investigative	11316581	C19H19ClN2O6S	438.9	CC1=C(C(=NO1)C2=C(C(=C(C=C2OC)OC)Cl)OC)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX9FN0	4-[2-(3,5-Dichloro-4-methoxyphenyl)-1-cyclopentenyl]benzenesulfonamide	Investigative	10692230	C18H17Cl2NO3S	398.3	COC1=C(C=C(C=C1Cl)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)N)Cl	IC50 = 71600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BX9Z2M	Cauloside D	Investigative	21630094	C53H86O22	1075.2	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXF5Z3	1-[4-[2-Methyl-5-(4-methylsulfonylphenyl)pyrrol-1-yl]phenyl]ethanone	Investigative	10760536	C20H19NO3S	353.4	CC1=CC=C(N1C2=CC=C(C=C2)C(=O)C)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXFN62	2-(4-Fluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine	Investigative	45268615	C24H18F2N2O2S	436.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)CC4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXGP98	2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine	Investigative	44395179	C19H14FN3O2S	367.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C3C=CC=NN3N=C2C4=CC(=CC=C4)F	IC50 = 58300 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXH3D6	N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]methanesulfonamide	Investigative	11302033	C12H10Cl2N2O3S	333.2	CS(=O)(=O)NC1=C(C=NC=C1)OC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXH76R	2-[5-Methoxy-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid	Investigative	18542341	C18H16N2O4	324.3	CC1=CC(=NC=C1)C(=O)C2=C(C3=C(N2)C=CC(=C3)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXJ06H	2-[2-(4-Ethylpyridine-2-carbonyl)-5-(trifluoromethoxy)-1H-indol-3-yl]acetic acid	Investigative	18542282	C19H15F3N2O4	392.3	CCC1=CC(=NC=C1)C(=O)C2=C(C3=C(N2)C=CC(=C3)OC(F)(F)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXK6S5	2-[2-(4-Methylpyridine-2-carbonyl)-5-(trifluoromethoxy)-1H-indol-3-yl]acetic acid	Investigative	18542198	C18H13F3N2O4	378.3	CC1=CC(=NC=C1)C(=O)C2=C(C3=C(N2)C=CC(=C3)OC(F)(F)F)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXK74D	2-(2-Oxochromen-7-yl)oxyethyl 5-(4-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137639040	C27H20ClN3O7S	566	C1=CC(=CC2=C1C=CC(=O)O2)OCCOC(=O)C3=NN(C(=C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 60000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXM7D2	2-(2-Oxochromen-4-yl)oxyethyl 5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137632978	C27H21N3O7S	531.5	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC(=O)OC5=CC=CC=C54	IC50 = 59230 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXMQ01	[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]methanol	Investigative	10832510	C17H15ClN2O3S	362.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CO	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXN62U	(1R,4Ar,7S)-7-(2-Methoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid	Investigative	9840662	C21H34O3	334.5	C[C@@]12CCC[C@@](C1CCC3C2=CC[C@](C3)(C)CCOC)(C)C(=O)O	IC50 = 84600 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXRM17	4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-phenylpyrimidin-2-amine	Investigative	45268625	C23H18FN3O2S	419.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N=C2C3=CC=C(C=C3)F)NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BXTQ80	4-[4-Chloro-5-(4-ethoxy-3-fluoro-phenyl)-imidazol-1-yl]-benzenesulfonamide	Investigative	10200745	C17H15ClFN3O3S	395.8	CCOC1=C(C=C(C=C1)C2=C(N=CN2C3=CC=C(C=C3)S(=O)(=O)N)Cl)F	IC50 = 76000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY0H7X	2-[4,5-Difluoro-2-(4-methylsulfonylphenyl)phenyl]-5-methylpyridine	Investigative	10522463	C19H15F2NO2S	359.4	CC1=CN=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY4O0G	Chembl4162061	Investigative	145959460	C20H18ClNO3S	387.9	CS(=O)(=O)C1=CC2=C(C=C1)N(C3=C2C(=O)CCC3)CC4=CC=C(C=C4)Cl	IC50 = 137000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY61QW	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1-phenethyl-1H-pyrazole	Investigative	10273651	C24H21FN2O2S	420.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C=C2C3=CC=C(C=C3)F)CCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY70EP	[5-(3-Amino-3-methyl-but-1-ynyl)-2-methoxy-phenyl]-[4-(2,4-difluoro-phenylamino)-phenyl]-methanone	Investigative	10295633	C25H22F2N2O2	420.4	CC(C)(C#CC1=CC(=C(C=C1)OC)C(=O)C2=CC=C(C=C2)NC3=C(C=C(C=C3)F)F)N	IC50 ~ 80000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY76UE	6-(4-Fluorophenyl)-7-[4-(methylsulfonyl)phenyl]spiro[3.4]oct-6-ene	Investigative	10155221	C21H21FO2S	356.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CCC3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY7R6Q	4-(4-Fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole-2-acetonitrile	Investigative	22911767	C18H13FN2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)CC#N)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BY9I6F	Sodium;2-[3-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56665212	C22H23NaO3	358.4	CC1=CC=C(C=C1)C2=C(C=CC(=C2)C(C)C(=O)[O-])CC3CCCC3=O.[Na+]	IC50 = 56000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYB95L	5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,4'']bipyridinyl	Investigative	9902732	C17H13ClN2O2S	344.8	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=CC(=C2)Cl)C3=CC=NC=C3	IC50 = 81000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYFH08	Benzenesulfonamide, p-((p-(dimethylamino)phenyl)azo)-	Investigative	75522	C14H16N4O2S	304.37	CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYG8L0	[3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-acetic acid	Investigative	44384088	C19H15FO4S2	390.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CSC(=C2C3=CC=C(C=C3)F)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYH9V5	4-[5-(4-Chlorophenyl)-3-(5-chlorothiophen-2-yl)pyrazol-1-yl]benzenesulfonamide	Investigative	9933456	C19H13Cl2N3O2S2	450.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=C(S4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYI94H	4-[4,5-Difluoro-2-(5-methylpyridin-2-yl)phenyl]benzenesulfonamide	Investigative	10784741	C18H14F2N2O2S	360.4	CC1=CN=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)N)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYL16A	Pyridine,2-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]-	Investigative	10786069	C17H14F3N3O2S	381.4	CC1=C(C=CC=N1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYR8I2	4-[3-(2-Bromophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide	Investigative	118732345	C22H18BrN3O3S	484.4	C1C2C(N(N=C2C3=CC=CC=C3O1)C4=CC=C(C=C4)S(=O)(=O)N)C5=CC=CC=C5Br	IC50 = 90230 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYU94E	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(3-morpholin-4-ylpropyl)prop-2-enamide	Investigative	71495779	C27H34N2O5	466.6	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)NCCCN3CCOCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BYVP12	4-[5-(3-Fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10452657	C16H11F4N3O2S	385.3	C1=CC(=CC(=C1)F)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ04AL	Morusin	Investigative	5281671	C25H24O6	420.5	CC(=CCC1=C(OC2=C(C1=O)C(=CC3=C2C=CC(O3)(C)C)O)C4=C(C=C(C=C4)O)O)C	IC50 = 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ0PV1	4-[5-Tert-butyl-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid	Investigative	88930915	C19H21FN2O3S	376.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ0U4E	N-(3-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16774950	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)N)C(F)(F)F	IC50 = 94000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ34NU	Falcarindiol	Investigative	5281148	C17H24O2	260.399	CCCCCCC/C=C\\[C@@H](C#CC#C[C@@H](C=C)O)O	IC50 = 66000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ3A8U	5-Amino-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53324576	C11H7ClF3NO3	293.62	C1=CC(=C(C2=C1OC(C(=C2)C(=O)O)C(F)(F)F)N)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ3M6H	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline	Investigative	49805180	C18H22N2O2	298.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ3O2L	1-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10664116	C18H16FNO2S	329.4	CCS(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ3VY2	2-(2-Chlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10692403	C17H12ClF3N2O2S	400.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=CC=C3Cl)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ4HJ1	1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-2-methyl-4-fluorobenzene	Investigative	9945403	C19H19FO2S	330.4	CC1=C(C=CC(=C1)F)C2=C(CCC2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ5BM2	2-Methyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	9861854	C17H21NO3S	319.4	CC1=NC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ5K0D	2-(2-Oxochromen-4-yl)oxyethyl 5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	137652137	C28H23N3O8S	561.6	COC1=CC=CC(=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)OCCOC4=CC(=O)OC5=CC=CC=C54	IC50 = 57260 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ6XU0	3-(4-Amino-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one	Investigative	11485547	C19H17NO5S	371.4	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ7FU5	4-[2-(3-Fluorophenyl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10572129	C16H11F4N3O2S	385.3	C1=CC(=CC(=C1)F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 67700 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ86BJ	2-(2-Chlorophenyl)-4-phenyl-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	22912306	C22H16ClNO2S2	426	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZ8P2I	6-(3,4-Dichlorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene	Investigative	10596725	C20H18Cl2O2S	393.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CC3)C4=CC(=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZF79Q	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-diethylprop-2-enamide	Investigative	71495991	C24H29NO4	395.5	CCN(CC)C(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZI10N	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-propylprop-2-enamide	Investigative	71495783	C23H27NO4	381.5	CCCNC(=O)/C=C/C1=C(C=C(C=C1OC)OC)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZI80J	5-(4-Fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid	Investigative	10666285	C16H12FN3O4S	361.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZK0D1	N-(Phenylsulfonyl)Picolinamide	Investigative	23002400	C12H10N2O3S	262.29	C1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=CC=CC=N2	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZM09W	(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-morpholin-4-ylprop-2-en-1-one	Investigative	71652685	C24H27NO5	409.5	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)N3CCOCC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZM46C	3-[4-(Trifluoromethyl)phenyl]-4-[4-(methylsulfonyl)phenyl]-4-oxazoline-2-one	Investigative	10691358	C17H12F3NO4S	383.3	CS(=O)(=O)C1=CC=C(C=C1)C2=COC(=O)N2C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZQ1M2	2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-yl]-ethanol	Investigative	10836221	C20H17F4NO3S	427.4	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZQ31A	N-(4-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16777326	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZQ38C	3-(3,5-Difluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	21472751	C18H14F2O5S	380.4	CC1(C(=C(C(=O)O1)C2=CC(=CC(=C2)F)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 ~ 90000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZQ92X	4-[2-(3-Fluoro-4-(trifluoromethyl)phenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10738786	C19H16F4O2S	384.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZQ9L7	Rofecoxib-threo-3,4-dihydrohydroxy acid	Investigative	44323831	C17H18O5S	334.4	CS(=O)(=O)C1=CC=C(C=C1)[C@@H](CO)[C@@H](C2=CC=CC=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZUE75	(E)-N-Cyclopropyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide	Investigative	71495990	C23H25NO4	379.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)NC3CC3	IC50 ~ 50000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	BZY5H2	2-Methyl-4-(5-ethyl-2-thienyl)-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	44374403	C17H17NO3S2	347.5	CCC1=CC=C(S1)C2=C(OC(=N2)C)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D01SNR	Firocoxib	Investigative	208910	C17H20O5S	336.4	CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D03FXI	4-(4-nitro-benzylideneamino)-benzenesulfonamide	Investigative	564225	C13H11N3O4S	305.31	C1=CC(=CC=C1C=NC2=CC=C(C=C2)S(=O)(=O)N)[N+](=O)[O-]	IC50 = 141250 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D03NMM	AM-643	Investigative	46843035	C36H39N4NaO4S	646.8	CC1=CN=C(C=C1)COC2=CC3=C(C=C2)N(C(=C3SC(C)(C)C)CC(C)(C)C(=O)[O-])CC4=CC=C(C=C4)C5=NC=C(C=N5)OC.[Na+]	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D04HRS	4-((4-hydroxyphenyl)diazenyl)benzenesulfonamide	Investigative	404195	C12H11N3O3S	277.3	.	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D06YGF	Caffeic acid phenethyl ester	Investigative	5281787	C17H16O4	284.31	C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 58000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D09DMR	4-phenyliminomethyl-benzenesulfonamide	Investigative	44456679	C13H12N2O2S	260.31	C1=CC=C(C=C1)N=CC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 63590 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0EI8V	GW-637185X	Investigative	45268661	C16H18F3N3O2S	373.4	CCC(C)NC1=NC(=CC(=N1)C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)C	IC50 = 62000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0F3UR	4-(4-methyl-benzylideneamino)-benzenesulfonamide	Investigative	690836	C14H14N2O2S	274.34	CC1=CC=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 190470 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0FQ3N	3,4-dihydroxyxanthone	Investigative	5748382	C13H8O4	228.2	C1=CC=C2C(=C1)C(=O)C3=C(O2)C(=C(C=C3)O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0G3TK	KAEMPFEROL	Investigative	5280863	C15H10O6	286.24	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0JT8Y	4-(3-nitro-benzylideneamino)-benzenesulfonamide	Investigative	21177358	C13H11N3O4S	305.31	C1=CC(=CC(=C1)[N+](=O)[O-])C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 105630 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0QV6M	LM-4108	Investigative	4292	C27H25ClN2O3	460.9	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NCCC4=CC=CC=C4	IC50 ~ 66000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0S2II	4-(benzylideneamino)benzenesulfonamide	Investigative	308405	C13H12N2O2S	260.31	C1=CC=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 108340 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0S7LD	2,6-dihydroxy-1,7-dimethoxyxanthone	Investigative	5326145	C15H12O6	288.25	COC1=C(C=C2C(=C1)C(=O)C3=C(O2)C=CC(=C3OC)O)O	IC50 ~ 100000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0T2SD	4-(4-methyl-phenyliminomethyl)-benzenesulfonamide	Investigative	21862824	C14H14N2O2S	274.34	CC1=CC=C(C=C1)N=CC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 63220 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0X6RO	4-(4-fluoro-benzylideneamino)-benzenesulfonamide	Investigative	404324	C13H11FN2O2S	278.3	C1=CC(=CC=C1C=NC2=CC=C(C=C2)S(=O)(=O)N)F	IC50 = 159070 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0Y1YR	gingerol	Investigative	442793	C17H26O4	294.4	CCCCC[C@@H](CC(=O)CCC1=CC(=C(C=C1)O)OC)O	IC50 = 129000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0Y9ZO	4-(4-fluoro-phenyliminomethyl)-benzenesulfonamide	Investigative	21862753	C13H11FN2O2S	278.3	C1=CC(=CC=C1C=NC2=CC=C(C=C2)F)S(=O)(=O)N	IC50 = 80200 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0YZ5G	esculetin	Investigative	5281416	C9H6O4	178.14	C1=CC(=O)OC2=CC(=C(C=C21)O)O	IC50 = 57000 nM	Poor binder
T60529	Prostaglandin G/H synthase 1	D0Z1WF	4-((4-methoxyphenyl)diazenyl)benzenesulfonamide	Investigative	405489	C13H13N3O3S	291.33	COC1=CC=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder