TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T61339	Lysosomal alpha-glucosidase	D0HR8Z	Miglustat	Approved	51634	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 = 158000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B04ZLR	Orsellinic acid	Investigative	68072	C8H8O4	168.15	CC1=CC(=CC(=C1C(=O)O)O)O	IC50 ~ 100000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B0AE9S	Penicidone D	Investigative	122182015	C20H21NO7	387.4	C/C=C/C1=C(C(=O)C(=CN1)C(=O)C2=C(C=C(C=C2OC)OC)C(=O)OC)OC	IC50 ~ 100000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B31HIF	Orcinol	Investigative	10436	C7H8O2	124.14	CC1=CC(=CC(=C1)O)O	IC50 ~ 100000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B32KGO	2-(3,5-Dihydroxyphenyl)-3-methyl-5alpha-hydroxy-2-cyclopentene-1-one	Investigative	122182013	C12H12O4	220.22	CC1=C(C(=O)[C@H](C1)O)C2=CC(=CC(=C2)O)O	IC50 ~ 100000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B62RFK	5-Epi-Isofagomine	Investigative	10820691	C6H13NO3	147.17	C1[C@H]([C@H]([C@@H](CN1)O)O)CO	Ki = 86000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B6S0ZW	Pinazaphilone A	Investigative	122182011	C21H20O9	416.4	CC1=CC(=CC(=C1C(=O)O[C@]2([C@@H](CC3=C(C2=O)COC(=C3)/C=C/C(=O)O)O)C)O)O	IC50 = 81700 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B6VT9D	(2Z)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one O-(anilinocarbonyl)oxime	Investigative	3262578	C13H16N2O7	312.27	C1=CC=C(C=C1)NC(=O)ON=C2C(C(C(C(O2)CO)O)O)O	Ki = 75000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	B9SVW3	(2S,3R,4S,5R)-2-(Hydroxymethyl)-6-[[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methylimino]piperidine-3,4,5-triol	Investigative	136056121	C13H24N2O9	352.34	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](O1)CN=C2[C@H]([C@H]([C@@H]([C@@H](N2)CO)O)O)O)O)O)O	Ki = 100000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BFB5M6	3-O-Methylfunicone	Investigative	10548301	C20H20O8	388.4	C/C=C/C1=C(C(=O)C(=CO1)C(=O)C2=C(C=C(C=C2OC)OC)C(=O)OC)OC	IC50 ~ 100000 nM	Poor binder
T61339	Neutral alpha-glucosidase AB	BKB32N	(2R,3R,4R,5S)-2-(1-Hydroxy-propyl)-piperidine-3,4,5-triol	Investigative	44338547	C8H17NO4	191.22	CCC([C@@H]1[C@H]([C@@H]([C@H](CN1)O)O)O)O	Ki = 60000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BLBV83	5-Amino-1-(hydroxymethyl)cyclopentane-1,2,3,4-tetrol	Investigative	9815399	C6H13NO5	179.17	C(C1(C(C(C(C1O)O)O)N)O)O	IC50 = 162000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BPG3L6	Precose	Investigative	444254	C25H43NO18	645.6	C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO	IC50 = 102000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BTS68H	N-Methyl-1-deoxynojirimycin	Investigative	4381	C7H15NO4	177.2	CN1CC(C(C(C1CO)O)O)O	Ki = 54000 nM	Poor binder
T61339	Neutral alpha-glucosidase AB	BUA0Y3	(2R)-2alpha-Ethylpyrrolidine-3beta,4alpha-diol	Investigative	55287220	C6H13NO2	131.17	CC[C@@H]1[C@H]([C@@H](CN1)O)O	IC50 = 53000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BWA3K0	3-Anilino-5,7a-bis(hydroxymethyl)-2,4a,6,7-tetrahydrocyclopenta[b][1,4]oxazine-5,6,7-triol	Investigative	44322883	C15H20N2O6	324.33	C1C(=NC2C(C(C(C2(O1)CO)O)O)(CO)O)NC3=CC=CC=C3	IC50 ~ 118000 nM	Poor binder
T61339	Lysosomal alpha-glucosidase	BZE10A	5-[4-(4-Chlorophenyl)piperazin-1-yl]sulfonyl-1,3-dihydroindol-2-one	Investigative	44825296	C18H18ClN3O3S	391.9	C1CN(CCN1C2=CC=C(C=C2)Cl)S(=O)(=O)C3=CC4=C(C=C3)NC(=O)C4	IC50 = 94310 nM	Poor binder
T61339	Neutral alpha-glucosidase C	D03TYC	Alpha-Homonojirimycin	Investigative	159496	C7H15NO5	193.2	C([C@@H]1[C@H](C([C@H]([C@H](N1)CO)O)O)O)O	IC50 = 80000 nM	Poor binder