TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63505	Tyrosine-protein kinase ABL1	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 = 74000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0E7PQ	Vorinostat	Approved	5311	C14H20N2O3	264.32	C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D05ADP	R-roscovitine	Phase 2	160355	C19H26N6O	354.4	CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0YX2B	PMID28460551-Compound-2	Patented	5329102	C22H27FN4O2	398.5	CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)F)NC2=O)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0AUO7	[4-[(2S)-2-Acetamido-3-[[(2S)-1-[[(2S)-1-(dioctylamino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	10556625	C35H61N4O8P	696.9	CCCCCCCCN(CCCCCCCC)C(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 95900 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0H9IG	Ethyl 1-[3-oxo-3-(4-phenylmethoxyphenyl)propyl]piperidine-4-carboxylate;hydrochloride	Investigative	45260866	C24H30ClNO4	431.9	CCOC(=O)C1CCN(CC1)CCC(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0J7WQ	1-(5-Benzyl-1,3,4-thiadiazol-2-yl)-3-phenylurea	Investigative	825387	C16H14N4OS	310.4	C1=CC=C(C=C1)CC2=NN=C(S2)NC(=O)NC3=CC=CC=C3	Ki = 58000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0Q3NC	3-(Dimethylamino)-1-(3-hydroxy-4-phenylmethoxyphenyl)propan-1-one;hydrochloride	Investigative	45260879	C18H22ClNO3	335.8	CN(C)CCC(=O)C1=CC(=C(C=C1)OCC2=CC=CC=C2)O.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B0ZS7U	2-(Ethylcarbamoylamino)-N-pyridin-4-yl-3H-benzimidazole-5-carboxamide	Investigative	71655525	C16H16N6O2	324.34	CCNC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)NC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B17ENH	4-[(3-Methyl-4-oxo-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-yl)methylamino]benzoic acid	Investigative	137228151	C20H17N5O3	375.4	CC1=NN(C2=C1C(=O)NC(=N2)CNC3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B19OXA	1-Propan-2-yl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	127036143	C17H14F3N5	345.32	CC(C)N1C2=NC=NC(=C2C(=N1)C#CC3=CC(=CC=C3)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B1K9UL	1-(4-Phenylmethoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride	Investigative	45260846	C21H26ClNO2	359.9	C1CCN(CC1)CCC(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B1P5ZV	[1-(4-Methylpiperazin-1-yl)-3-phenylpropan-2-yl] N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate	Investigative	137636138	C36H40BrN7O2S	714.7	CC(CN1C2=C(C=N1)C(=NC(=N2)SC)N(C3=CC(=CC=C3)Br)C(=O)OC(CC4=CC=CC=C4)CN5CCN(CC5)C)C6=CC=CC=C6	Ki ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B1XR0L	1-Methyl-3-(quinolin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905204	C15H12N6	276.3	CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)N=CC=C4)N	IC50 = 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B2CME9	N-(3-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-7-amine	Investigative	127033165	C20H16N4O	328.4	COC1=CC=CC(=C1)NC2=NC=C3C(=C2)N=C(C=N3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B2F6BW	2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[b]thiophene-5-carbaldehyde	Investigative	24905163	C17H15N5OS	337.4	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(S3)C=CC(=C4)C=O)N	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B2NRQ3	1-[7-(3,4-Dimethoxyphenyl)-1,5-naphthyridin-2-yl]-3-ethylurea	Investigative	53239374	C19H20N4O3	352.4	CCNC(=O)NC1=NC2=C(C=C1)N=CC(=C2)C3=CC(=C(C=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B2Q4RY	(2S)-2-[[(2S,3S)-2-[[(2S)-4-Carboxy-2-[[(2S)-4-carboxy-2-[[2-phenyl-3-(4-phosphonooxyphenyl)propanoyl]amino]butanoyl]amino]butanoyl]amino]-3-methylpentanoyl]amino]pentanedioic acid	Investigative	70691280	C36H47N4O16P	822.7	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)C(CC1=CC=C(C=C1)OP(=O)(O)O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B34OQI	1-[7-(1-Methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]-3-(2-phenylethyl)urea	Investigative	53239587	C21H20N6O	372.4	CN1C=C(C=N1)C2=CC3=C(C=CC(=N3)NC(=O)NCCC4=CC=CC=C4)N=C2	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B3HGC4	3-[(E)-2-[6-(Cyclopropylamino)purin-9-yl]ethenyl]-4-methyl-N-(3-propan-2-ylphenyl)benzamide	Investigative	44221731	C27H28N6O	452.6	CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(C)C)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 60000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B3T9QN	Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44219749	C24H29N7O5	495.5	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B3U5GT	3-(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxy-N-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide	Investigative	118728502	C18H24N6O4S	420.5	CCOC1=C(C=C(C=C1)S(=O)(=O)NC(C)(C)CO)C2=NC3=C(N=N2)N(N=C3C)C	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B3V7LZ	2-[(Dimethylamino)methyl]-3-(3,4-dimethylphenyl)sulfanyl-1-(4-phenylmethoxyphenyl)propan-1-one;hydrochloride	Investigative	45264671	C27H32ClNO2S	470.1	CC1=C(C=C(C=C1)SCC(CN(C)C)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3)C.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B46VJZ	2-[6-(Anilinomethyl)-3-methyl-4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl]acetonitrile	Investigative	127043441	C21H18N6O	370.4	CC1=NN(C2=C1C(=O)N(C(=N2)CNC3=CC=CC=C3)CC#N)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4ESV1	(E)-1-(3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methylphenyl)-3-(3-(trifluoromethyl)phenyl)urea	Investigative	44222636	C25H22F3N7O	493.5	CC1=C(C=C(C=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 62000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4G2QZ	Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605035	C22H27N7O3	437.5	COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4HU5D	Cyclapolin 9	Investigative	2779952	C9H4F3N3O4S	307.21	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4HX3I	1-Isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905171	C12H13N7	255.28	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CN=CN=C3)N	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4LGE2	2-(3-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)acetonitrile	Investigative	24905167	C16H16N6	292.34	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=CC(=C3)CC#N)N	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4NZ6S	3-[1-(4-Chlorobenzyl)-1h-indol-3-yl]-n-(4-nitrophenyl)propanamide	Investigative	46934144	C24H20ClN3O3	433.9	C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)CCC(=O)NC4=CC=C(C=C4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4OJF2	[4-[2-[(Dimethylamino)methyl]prop-2-enoyl]phenyl] 4-(dimethylcarbamoyl)benzenesulfonate;hydrochloride	Investigative	45260823	C21H25ClN2O5S	453	CN(C)CC(=C)C(=O)C1=CC=C(C=C1)OS(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C.Cl	IC50 = 70000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4SNV3	12-Anilino-3,8-diphenyl-1,3,4,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-2(6),4,9,11-tetraen-7-one	Investigative	134132321	C24H17N7O	419.4	C1=CC=C(C=C1)NC2=NN=C3N2C4=C(C=NN4C5=CC=CC=C5)C(=O)N3C6=CC=CC=C6	IC50 = 150000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B4YQZ3	1-(3-Methoxyphenyl)-3-(3-phenylpyrido[3,4-b]pyrazin-8-yl)urea	Investigative	127034308	C21H17N5O2	371.4	COC1=CC=CC(=C1)NC(=O)NC2=C3C(=CN=C2)N=C(C=N3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B5ON0T	6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789254	C14H20N6	272.35	C1CCNC2(C1)CCN(CC2)C3=NC=NC4=C3NC=N4	IC50 = 126000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B5RL4N	2-[(Dimethylamino)methyl]-1-(4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride	Investigative	45260877	C19H22ClNO2	331.8	CN(C)CC(=C)C(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B5VY3S	6-(Ethoxymethyl)-3,5-dimethyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	127043205	C16H18N4O2	298.34	CCOCC1=NC2=C(C(=NN2C3=CC=CC=C3)C)C(=O)N1C	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B5WB7E	[[2-[(Dimethylamino)methyl]-3-oxo-3-(4-phenylmethoxyphenyl)propyl]amino]urea;hydrochloride	Investigative	45264655	C20H27ClN4O3	406.9	CN(C)CC(CNNC(=O)N)C(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B60ANF	Methyl 5-[(2-fluoro-6-methoxybenzoyl)amino]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate	Investigative	46866423	C17H14FN3O4	343.31	COC1=C(C(=CC=C1)F)C(=O)NC2=CN=C3C(=C2)C=C(N3)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B65HCJ	4-[4-(2-Dimethylaminomethyl-acryloyl)-phenoxysulfonyl]-benzoic acid	Investigative	10318154	C19H19NO6S	389.4	CN(C)CC(=C)C(=O)C1=CC=C(C=C1)OS(=O)(=O)C2=CC=C(C=C2)C(=O)O	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B6BML2	2-[6-(Chloromethyl)-3-methyl-4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl]acetonitrile	Investigative	127043366	C15H12ClN5O	313.74	CC1=NN(C2=C1C(=O)N(C(=N2)CCl)CC#N)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B6H9BO	5-[(2-Bromobenzoyl)amino]-N-[3-(dimethylamino)propyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide	Investigative	46861577	C20H22BrN5O2	444.3	CN(C)CCCNC(=O)C1=CC2=CC(=CN=C2N1)NC(=O)C3=CC=CC=C3Br	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B6J9NQ	4-Pyridin-4-yl-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine	Investigative	9799152	C17H12F4N4O	364.3	C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B6RE9N	4-[[4-[2-Methylene-3-(dimethylamino)propionyl]phenoxy]sulfonyl]salicylic acid	Investigative	10408993	C19H19NO7S	405.4	CN(C)CC(=C)C(=O)C1=CC=C(C=C1)OS(=O)(=O)C2=CC(=C(C=C2)C(=O)O)O	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B6TCU4	N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-7-amine	Investigative	127031677	C23H21N5O	383.4	C1COCCN1C2=CC=C(C=C2)NC3=NC=C4C(=C3)N=C(C=N4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B74KYQ	6-(Ethoxymethyl)-3-methyl-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228146	C15H16N4O2	284.31	CCOCC1=NC2=C(C(=NN2C3=CC=CC=C3)C)C(=O)N1	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B76FRE	1-Tert-butyl-3-[7-(3,4-dimethoxyphenyl)-1,5-naphthyridin-2-yl]urea	Investigative	53239375	C21H24N4O3	380.4	CC(C)(C)NC(=O)NC1=NC2=C(C=C1)N=CC(=C2)C3=CC(=C(C=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7BZJ1	2-Cyano-2-(3,4-dihydroxy-benzyl)-thioacetamide	Investigative	44318047	C10H10N2O2S	222.27	C1=CC(=C(C=C1CC(C#N)C(=S)N)O)O	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7F3GM	N-(5-Tert-butyl-2-methylpyrazol-3-yl)-3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylbenzamide	Investigative	44221732	C26H30N8O	470.6	CC1=C(C=C(C=C1)C(=O)NC2=CC(=NN2C)C(C)(C)C)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 146000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7ILR1	2-[4-Amino-3-(3-ethoxy-4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethanol	Investigative	52940797	C16H19N5O3	329.35	CCOC1=C(C=CC(=C1)C2=NN(C3=NC=NC(=C23)N)CCO)OC	IC50 = 65000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7O4PF	5-(2-Ethoxy-5-pyrrolidin-1-ylsulfonylphenyl)-1,3-dimethylpyrazolo[4,3-e][1,2,4]triazine	Investigative	90675937	C18H22N6O3S	402.5	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCCC2)C3=NC4=C(N=N3)N(N=C4C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7P4NU	N-(3-Ethynylphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine	Investigative	127031076	C21H14N4	322.4	C#CC1=CC(=CC=C1)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7P4UH	[4-[(2S)-2-Acetamido-3-[[(2S)-3-methyl-1-oxo-1-[[(2S)-1-oxo-1-(2-phenylethylamino)propan-2-yl]amino]butan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	10626988	C27H37N4O8P	576.6	C[C@@H](C(=O)NCCC1=CC=CC=C1)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C	IC50 = 72000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7P8DA	4-[3-(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxyphenyl]sulfonylmorpholine	Investigative	90675935	C18H22N6O4S	418.5	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCOCC2)C3=NC4=C(N=N3)N(N=C4C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7S1XJ	4-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-2-chlorobenzamide	Investigative	52942235	C15H15ClN6O	330.77	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)C(=O)N)Cl)N	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7TPL6	2-(Benzylsulfanyl)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile	Investigative	1898760	C21H18N2S2	362.5	C1CCC2=C(C1)C(=C(C(=N2)SCC3=CC=CC=C3)C#N)C4=CC=CS4	IC50 = 72000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B84IMW	1,3-Dimethyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-amine	Investigative	90654804	C16H19N7O2S	373.4	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N4CCCC4)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B8F2CJ	3-Methyl-6-(morpholin-4-ylmethyl)-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228154	C17H19N5O2	325.4	CC1=NN(C2=C1C(=O)NC(=N2)CN3CCOCC3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B8FA3E	2-Propen-1-one, 2-((dimethylamino)methyl)-1-phenyl-, hydrochloride	Investigative	3063374	C12H16ClNO	225.71	CN(C)CC(=C)C(=O)C1=CC=CC=C1.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B8MAO4	2-(4-Fluorobenzylsulfanyl)-4-(2-thienyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile	Investigative	1886699	C21H17FN2S2	380.5	C1CCC2=C(C1)C(=C(C(=N2)SCC3=CC=C(C=C3)F)C#N)C4=CC=CS4	IC50 = 74000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B8P3YL	2-Amino-6-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-4-(3-thienyl)pyridine-3,5-dicarbonitrile	Investigative	46838967	C19H11ClN4OS2	410.9	C1=CC(=CC=C1C(=O)CSC2=C(C(=C(C(=N2)N)C#N)C3=CSC=C3)C#N)Cl	IC50 = 60000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B8YTQ3	CID 49806721	Investigative	49806721	C28H30N4O2	454.6	CCC1=CC2=C(C=C1N3CCN(CC3)C4COC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B9KQ2X	N-(1,3-Dihydroxy-2-methylpropan-2-yl)-3-(1,3-dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxybenzenesulfonamide	Investigative	118728501	C18H24N6O5S	436.5	CCOC1=C(C=C(C=C1)S(=O)(=O)NC(C)(CO)CO)C2=NC3=C(N=N2)N(N=C3C)C	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B9TCH1	(4-(2-Aminophenylcarbamoyl)benzylamino)methyl nicotinate	Investigative	44572384	C21H20N4O3	376.4	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNCOC(=O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	B9VQ1H	(3Z)-5-Amino-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one	Investigative	23647620	C13H11N3O	225.25	C1=CNC(=C1)/C=C\\2/C3=C(C=CC(=C3)N)NC2=O	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BA6QT9	6-[(4-Hydroxyanilino)methyl]-3,5-dimethyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	127045497	C20H19N5O2	361.4	CC1=NN(C2=C1C(=O)N(C(=N2)CNC3=CC=C(C=C3)O)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BA6TG4	(E)-N-(4-Methyl-3-(2-(6-(cyclopropylamino)-9H-purin-9-yl)vinyl)-phenyl)-3-(trifluoromethyl)benzamide	Investigative	44221514	C25H21F3N6O	478.5	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 74000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BA9N2U	2-[6-(Methoxymethyl)-3-methyl-4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl]acetonitrile	Investigative	127043202	C16H15N5O2	309.32	CC1=NN(C2=C1C(=O)N(C(=N2)COC)CC#N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BB2S4A	2-((4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one	Investigative	24905149	C28H23N7O2	489.5	CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C(=N4)C6=CC(=CC=C6)O)N	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BB4I1G	1-(3-Methoxyphenyl)-3-(2-phenylpyrido[3,4-b]pyrazin-5-yl)urea	Investigative	127030427	C21H17N5O2	371.4	COC1=CC=CC(=C1)NC(=O)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BB59SE	4-[(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]-N-(1-hydroxy-3-methylbutan-2-yl)benzenesulfonamide	Investigative	90654799	C17H23N7O3S	405.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NC(CO)C(C)C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BB80MQ	2-[(Dimethylamino)methyl]-1-(4-phenylmethoxyphenyl)-3-phenylsulfanylpropan-1-one;hydrochloride	Investigative	45264640	C25H28ClNO2S	442	CN(C)CC(CSC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BBD4X5	2-(Morpholin-4-ylmethyl)-1-(4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride	Investigative	45260829	C21H24ClNO3	373.9	C=C(CN1CCOCC1)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BBFY93	1-(3-Phenylpyrido[3,4-b]pyrazin-8-yl)-3-prop-2-enylurea	Investigative	127032542	C17H15N5O	305.33	C=CCNC(=O)NC1=C2C(=CN=C1)N=C(C=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BBWU45	6-(4-Amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905227	C19H18N6O	346.4	C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)NC(=O)C=C5)N	IC50 = 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BC8XV0	[4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine	Investigative	19966997	C18H12ClF4N3O	397.8	C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BCF13G	Tert-butyl 6-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-4-ylcarbamate	Investigative	24905231	C22H25N7O2	419.5	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=CN=C4C=C3)NC(=O)OC(C)(C)C)N	IC50 = 65000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BCH07I	1-Ethyl-3-[6-(4-methylpiperazine-1-carbonyl)-1H-benzimidazol-2-yl]urea	Investigative	71655468	C16H22N6O2	330.38	CCNC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)N3CCN(CC3)C	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BCXK97	2-[(Dimethylamino)methyl]-1-(3-hydroxy-4-phenylmethoxyphenyl)prop-2-en-1-one;hydrochloride	Investigative	45260812	C19H22ClNO3	347.8	CN(C)CC(=C)C(=O)C1=CC(=C(C=C1)OCC2=CC=CC=C2)O.Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BDGW97	2-(4-Methylpiperazin-1-yl)ethyl N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate	Investigative	71762922	C29H34BrN7O2S	624.6	CC(CN1C2=C(C=N1)C(=NC(=N2)SC)N(C3=CC(=CC=C3)Br)C(=O)OCCN4CCN(CC4)C)C5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BDO1L8	1-(4-Phenylmethoxyphenyl)-2-(piperazin-1-ylmethyl)prop-2-en-1-one;hydrochloride	Investigative	45260839	C21H25ClN2O2	372.9	C=C(CN1CCNCC1)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BDV8X5	4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-benzenesulfonamide	Investigative	24905338	C14H16N6O2S	332.38	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)S(=O)(=O)N)N	IC50 = 58000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BDXT45	3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione	Investigative	11530963	C21H18N2O5	378.4	COC1=CC(=CC(=C1OC)OC)C2=C(C(=O)NC2=O)C3=CNC4=CC=CC=C43	IC50 = 93000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BE6BF9	[4-[(2S)-2-Acetamido-3-[[(2S)-1-[3-cyclohexylpropyl(methyl)amino]-1-oxobutan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	44300215	C25H40N3O7P	525.6	CC[C@@H](C(=O)N(C)CCCC1CCCCC1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C	IC50 = 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BF1U7Y	4-(Dimethylamino)-1-(4-phenylmethoxyphenyl)butan-1-one;hydrochloride	Investigative	45260875	C19H24ClNO2	333.8	CN(C)CCCC(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BF3XS1	3-(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxy-N-(2-morpholin-4-ylethyl)benzenesulfonamide	Investigative	90675940	C20H27N7O4S	461.5	CCOC1=C(C=C(C=C1)S(=O)(=O)NCCN2CCOCC2)C3=NC4=C(N=N3)N(N=C4C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BF4U1Y	[3-(5-Chlorothiophen-3-yl)-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]urea	Investigative	5329656	C15H9ClN4O2S	344.8	C1=CC2=C(C(=C1)NC(=O)N)C(=O)C3=C2NN=C3C4=CSC(=C4)Cl	IC50 ~ 60000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BFH3Y7	6-(Anilinomethyl)-3,5-dimethyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	127043440	C20H19N5O	345.4	CC1=NN(C2=C1C(=O)N(C(=N2)CNC3=CC=CC=C3)C)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BFL57T	2-(2-Aminoethylsulfanylmethyl)-3-(dimethylamino)-1-(4-phenylmethoxyphenyl)propan-1-one;hydrochloride	Investigative	45260874	C21H29ClN2O2S	409	CN(C)CC(CSCCN)C(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2.Cl	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BG54RO	(E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(3-(tert-butyl)phenyl)benzamide	Investigative	44222286	C28H30N6O	466.6	CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(C)(C)C)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 59000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BGD6V8	6-(Chloromethyl)-3,5-dimethyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	127044692	C14H13ClN4O	288.73	CC1=NN(C2=C1C(=O)N(C(=N2)CCl)C)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BGVU25	N-(Pyridin-4-yl)-3-[1-(4-chlorobenzyl)indol-3-yl]-propanamide	Investigative	16723801	C23H20ClN3O	389.9	C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)CCC(=O)NC4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BH1FA3	6-(4-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-4H-chromen-4-one	Investigative	24905234	C15H11N5O2	293.28	CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC=CC4=O)N	IC50 = 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BH1N4K	5-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)pyridine-2-carbonitrile	Investigative	24905341	C14H13N7	279.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CN=C(C=C3)C#N)N	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BH9N3O	N-(3-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine	Investigative	127033758	C20H16N4O	328.4	COC1=CC=CC(=C1)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BI6S5B	1-Propanone, 3-(4-morpholinyl)-1-(4-(phenylmethoxy)phenyl)-, hydrochloride	Investigative	2807057	C20H24ClNO3	361.9	C1COCCN1CCC(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BIC9Y6	BrC=1C=C(C=CC=1)N(C(OCCN1CCN(CC1)C)=O)C1=C2C(=NC(=N1)SCCN1CCOCC1)N(N=C2)CC(C1=CC=CC=C1)Cl	Investigative	121316022	C33H40BrClN8O3S	744.1	CN1CCN(CC1)CCOC(=O)N(C2=CC(=CC=C2)Br)C3=NC(=NC4=C3C=NN4CC(C5=CC=CC=C5)Cl)SCCN6CCOCC6	Ki ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BIV45N	N-Cyclohexyl-1-[(E)-styryl]pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	11370613	C19H21N5	319.4	C1CCC(CC1)NC2=C3C=NN(C3=NC=N2)/C=C/C4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BJ6BZ2	N-(2-Aminoethyl)-3-(1,3-dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxybenzenesulfonamide	Investigative	90675939	C16H21N7O3S	391.5	CCOC1=C(C=C(C=C1)S(=O)(=O)NCCN)C2=NC3=C(N=N2)N(N=C3C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BK0NO8	2-[6-[(4-Hydroxyanilino)methyl]-3-methyl-4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl]acetonitrile	Investigative	127043621	C21H18N6O2	386.4	CC1=NN(C2=C1C(=O)N(C(=N2)CNC3=CC=C(C=C3)O)CC#N)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BK7BF6	5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propylpyrazolo[4,3-e][1,2,4]triazine	Investigative	72543811	C21H29N7O3S	459.6	CCCC1=NN(C2=C1N=C(N=N2)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BKNG37	6-(Methoxymethyl)-3-methyl-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228145	C14H14N4O2	270.29	CC1=NN(C2=C1C(=O)NC(=N2)COC)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BL45TP	N-(4-Methyl-3-(2-(6-(methylamino)-9H-purin-9-yl)ethyl)phenyl)-3-(trifluoromethyl)-benzamide	Investigative	23649898	C23H21F3N6O	454.4	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)CCN3C=NC4=C(N=CN=C43)NC	IC50 = 96000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BL5SD0	2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one	Investigative	14624081	C21H20ClNO5	401.8	CN1CCC([C@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O	IC50 = 110000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BL8E9J	6-(Methoxymethyl)-3,5-dimethyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	127043201	C15H16N4O2	284.31	CC1=NN(C2=C1C(=O)N(C(=N2)COC)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BLY2D9	2-Bromo-N-[2-(1H-pyrrol-2-ylmethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide	Investigative	46866425	C19H15BrN4O	395.3	C1=CC=C(C(=C1)C(=O)NC2=CN=C3C(=C2)C=C(N3)CC4=CC=CN4)Br	IC50 = 63330 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BM20LA	1,3-Dimethyl-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazolo[4,3-e][1,2,4]triazin-5-amine	Investigative	90654802	C17H22N8O2S	402.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N4CCN(CC4)C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BM8AQ9	N-Benzyl-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	137644946	C21H19FN4S	378.5	CSC1=NC(=C2C=CN(C2=N1)CC3=CC=C(C=C3)F)NCC4=CC=CC=C4	IC50 = 70000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BMC31A	1-Benzyl-3-[7-(1-methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]urea	Investigative	52936268	C20H18N6O	358.4	CN1C=C(C=N1)C2=CC3=C(C=CC(=N3)NC(=O)NCC4=CC=CC=C4)N=C2	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BMP0C7	Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605037	C25H33N7O3	479.6	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BMYZ40	3-(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxy-N,N-diethylbenzenesulfonamide	Investigative	118722001	C18H24N6O3S	404.5	CCN(CC)S(=O)(=O)C1=CC(=C(C=C1)OCC)C2=NC3=C(N=N2)N(N=C3C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BN1I2G	3-(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)-4-ethoxy-N-(2-hydroxyethyl)benzenesulfonamide	Investigative	90675941	C16H20N6O4S	392.4	CCOC1=C(C=C(C=C1)S(=O)(=O)NCCO)C2=NC3=C(N=N2)N(N=C3C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BN24SQ	2-Benzothiazolecarboxamide, 7-nitro-5-[(trifluoromethyl)thio]-, 3-oxide	Investigative	9548013	C9H4F3N3O4S2	339.3	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])SC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BO1V0K	3-Methyl-1-phenyl-6-(piperidin-1-ylmethyl)-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228153	C18H21N5O	323.4	CC1=NN(C2=C1C(=O)NC(=N2)CN3CCCCC3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BOKJ71	N-(3-Chloro-4-fluorophenyl)-3-phenylpyrido[3,4-b]pyrazin-8-amine	Investigative	127030124	C19H12ClFN4	350.8	C1=CC=C(C=C1)C2=NC3=CN=CC(=C3N=C2)NC4=CC(=C(C=C4)F)Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BPV4H6	2-(6-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide	Investigative	46232556	C21H17Cl2FN2O2	419.3	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)C4CC4C(=O)N	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BQX3F8	2-Amino-7-methyl-4-[(4-methylphenyl)methylamino]-9H-pyrimido[4,5-b]indol-6-ol	Investigative	137659496	C19H19N5O	333.4	CC1=CC=C(C=C1)CNC2=NC(=NC3=C2C4=C(N3)C=C(C(=C4)O)C)N	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BR4X5J	(3-Nitro-phenyl)-(4-pyridin-4-yl-pyrimidin-2-yl)-amine	Investigative	9814609	C15H11N5O2	293.28	C1=CC(=CC(=C1)[N+](=O)[O-])NC2=NC=CC(=N2)C3=CC=NC=C3	IC50 = 61000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BR8C5F	2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(3-thienyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile	Investigative	46838818	C22H18N2OS2	390.5	C1CCC2=C(C1)C(=C(C(=N2)SCC(=O)C3=CC=CC=C3)C#N)C4=CSC=C4	IC50 ~ 150000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BS38DM	6-(Diethylaminomethyl)-3-methyl-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228152	C17H21N5O	311.4	CCN(CC)CC1=NC2=C(C(=NN2C3=CC=CC=C3)C)C(=O)N1	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BSX1W7	4-Chloro-N'-(4-oxo-1,5-diphenylpyrazolo[3,4-d]pyrimidin-6-yl)benzohydrazide	Investigative	134150115	C24H17ClN6O2	456.9	C1=CC=C(C=C1)N2C3=C(C=N2)C(=O)N(C(=N3)NNC(=O)C4=CC=C(C=C4)Cl)C5=CC=CC=C5	IC50 = 65600 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BT3H1C	N-(4-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine	Investigative	127031384	C20H16N4O	328.4	COC1=CC=C(C=C1)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BT59FK	N-[3-[(E)-2-[6-[3-(Dimethylamino)propylamino]purin-9-yl]ethenyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide	Investigative	44221727	C27H28F3N7O	523.6	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)/C=C/N3C=NC4=C(N=CN=C43)NCCCN(C)C	IC50 = 157000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BT9FO8	1-(4-Phenylmethoxyphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one;hydrochloride	Investigative	45260884	C22H26ClNO2	371.9	C=C(CN1CCCCC1)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BTL9X5	1-Propanone, 3-(dimethylamino)-1-(4-(phenylmethoxy)phenyl)-, hydrochloride	Investigative	3039850	C18H22ClNO2	319.8	CN(C)CCC(=O)C1=CC=C(C=C1)OCC2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BU01SV	(E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-[3-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]benzamide	Investigative	44222822	C29H28F3N7O2	563.6	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3CCOCC3)/C=C/N4C=NC5=C(N=CN=C54)NC6CC6	IC50 = 72000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BU4N3K	Methyl 5-[(2-bromobenzoyl)amino]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate	Investigative	46866422	C16H12BrN3O3	374.19	COC(=O)C1=CC2=CC(=CN=C2N1)NC(=O)C3=CC=CC=C3Br	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BU9QK8	1-[7-(1-Methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]-3-phenylurea	Investigative	53236671	C19H16N6O	344.4	CN1C=C(C=N1)C2=CC3=C(C=CC(=N3)NC(=O)NC4=CC=CC=C4)N=C2	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BUF0Q1	Methyl 2-[2-[(dimethylamino)methyl]-3-oxo-3-(4-phenylmethoxyphenyl)propyl]sulfanylbenzoate;hydrochloride	Investigative	45264620	C27H30ClNO4S	500	CN(C)CC(CSC1=CC=CC=C1C(=O)OC)C(=O)C2=CC=C(C=C2)OCC3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BUM7K8	5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1,3-dimethylpyrazolo[4,3-e][1,2,4]triazine	Investigative	90675933	C19H25N7O3S	431.5	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(N=N3)N(N=C4C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BV2S5G	(3Z)-5-Amino-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one	Investigative	15551239	C15H15N3O	253.3	CC1=CC(=C(N1)/C=C\\2/C3=C(C=CC(=C3)N)NC2=O)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BXB01F	5-[4-Amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	122163152	C18H21N7O3	383.4	CCOC(CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N)OCC	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BXT47G	5-(2-Ethoxy-5-piperazin-1-ylsulfonylphenyl)-1,3-dimethylpyrazolo[4,3-e][1,2,4]triazine	Investigative	90675934	C18H23N7O3S	417.5	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCNCC2)C3=NC4=C(N=N3)N(N=C4C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BY04GR	1-(4-Methylpiperazin-1-yl)propan-2-yl N-(3-bromophenyl)-N-[6-methylsulfanyl-1-(2-phenylpropyl)pyrazolo[3,4-d]pyrimidin-4-yl]carbamate	Investigative	121305843	C30H36BrN7O2S	638.6	CC(CN1C2=C(C=N1)C(=NC(=N2)SC)N(C3=CC(=CC=C3)Br)C(=O)OC(C)CN4CCN(CC4)C)C5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BY0G8O	2-[6-(Ethoxymethyl)-3-methyl-4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl]acetonitrile	Investigative	127043619	C17H17N5O2	323.35	CCOCC1=NC2=C(C(=NN2C3=CC=CC=C3)C)C(=O)N1CC#N	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BYA5E9	1-Tert-butyl-3-[7-(4-hydroxy-3-methoxyphenyl)-1,5-naphthyridin-2-yl]urea	Investigative	136065882	C20H22N4O3	366.4	CC(C)(C)NC(=O)NC1=NC2=C(C=C1)N=CC(=C2)C3=CC(=C(C=C3)O)OC	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BZ67WY	6-[(2E)-2-[(4-Fluorophenyl)methylidene]hydrazinyl]-1,5-diphenylpyrazolo[3,4-d]pyrimidin-4-one	Investigative	134156776	C24H17FN6O	424.4	C1=CC=C(C=C1)N2C3=C(C=N2)C(=O)N(C(=N3)N/N=C/C4=CC=C(C=C4)F)C5=CC=CC=C5	IC50 = 110000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BZA59X	3-((4-(Dimethylamino)naphthalen-1-yl)methylene)-4-methylindolin-2-one	Investigative	46233185	C22H20N2O	328.4	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(C4=CC=CC=C34)N(C)C	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	BZQ5E4	6-[(4-Hydroxyanilino)methyl]-3-methyl-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	137228150	C19H17N5O2	347.4	CC1=NN(C2=C1C(=O)NC(=N2)CNC3=CC=C(C=C3)O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D00ATA	(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one	Investigative	5908088	C13H10N2O	210.23	C1=CC=C2C(=C1)/C(=C/C3=CC=CN3)/C(=O)N2	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0CE3R	SU 6656	Investigative	5312137	C19H21N3O3S	371.5	CN(C)S(=O)(=O)C1=CC\\2=C(C=C1)NC(=O)/C2=C\\C3=CC4=C(N3)CCCC4	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0W7TU	NSC-73306	Investigative	947057	C16H14N4O2S	326.4	.	IC50 ~ 50000 nM	Poor binder
T63505	Tyrosine-protein kinase ABL1	D0Y1UL	(E)-3-(4-hydroxybenzylidene)indolin-2-one	Investigative	10561847	C15H11NO2	237.25	C1=CC=C2C(=C1)/C(=C\\C3=CC=C(C=C3)O)/C(=O)N2	IC50 ~ 50000 nM	Poor binder