TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63846	IL-1 receptor-associated kinase 1	BF2Z9T	N-(Azetidin-3-yl)-6-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyridin-2-amine	Investigative	25169382	C15H14ClN5	299.76	C1C(CN1)NC2=CC=CC(=N2)C3=CN=C4N3C=C(C=C4)Cl	IC50 = 195000 nM	Poor binder
T63846	IL-1 receptor-associated kinase 1	BMJ21N	3-[6-(Piperidin-4-ylamino)pyridin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Investigative	25169381	C18H18N6	318.4	C1CNCCC1NC2=CC=CC(=N2)C3=CN=C4N3C=C(C=C4)C#N	IC50 = 96000 nM	Poor binder
T63846	IL-1 receptor-associated kinase 1	BQX3F8	2-Amino-7-methyl-4-[(4-methylphenyl)methylamino]-9H-pyrimido[4,5-b]indol-6-ol	Investigative	137659496	C19H19N5O	333.4	CC1=CC=C(C=C1)CNC2=NC(=NC3=C2C4=C(N3)C=C(C(=C4)O)C)N	IC50 ~ 100000 nM	Poor binder
T63846	IL-1 receptor-associated kinase 1	BWC8X3	6-(6-Chloroimidazo[1,2-a]pyridin-3-yl)-N-piperidin-3-ylpyridin-2-amine	Investigative	25169384	C17H18ClN5	327.8	C1CC(CNC1)NC2=CC=CC(=N2)C3=CN=C4N3C=C(C=C4)Cl	IC50 = 175000 nM	Poor binder