TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63966	Vascular endothelial growth factor receptor 1	D0M0XB	Saracatinib	Phase 2	10302451	C27H32ClN5O5	542	CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B0CPW1	1-((5-(6-((4-Methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-(2-(trifluoromethyl)phenyl)urea	Investigative	44414847	C29H29F3N6OS	566.6	CN1CCN(CC1)CC2=CC3=C(C=C2)C4=NNC(=C4C3)C5=CC=C(S5)CNC(=O)NC6=CC=CC=C6C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B0K6WY	(3R,6S,9S,14S,17S,23S,26S)-9-[[(2S)-2-Acetamido-4-methylsulfanylbutanoyl]amino]-3-(4-aminobutyl)-N-[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]-17-(3-amino-3-oxopropyl)-6-[(2S)-butan-2-yl]-23-(1H-imidazol-5-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,7,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide	Investigative	53320001	C51H85N15O12S	1132.4	CC[C@H](C)[C@H]1C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCC[C@@H](C(=O)N1)NC(=O)[C@H](CCSC)NC(=O)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N)CCC(=O)N)CC3=CN=CN3)CCCCN	IC50 = 91600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B0X2YZ	3-[(3S,6S,9S,12R,17R,20S,23S,26S,29S,32S,35S,38S)-12-Amino-9-(3-amino-3-oxopropyl)-20,29-bis[(2S)-butan-2-yl]-26,32-bis(2-carboxyethyl)-35-(carboxymethyl)-17-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-3,23-bis[(4-hydroxyphenyl)methyl]-2,5,8,11,19,22,25,28,31,34,37-undecaoxo-14,15-dithia-1,4,7,10,18,21,24,27,30,33,36-undecazabicyclo[36.3.0]hentetracontan-6-yl]propanoic acid	Investigative	137635974	C71H104N16O24S2	1629.8	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CC(=O)O)CC3=CC=C(C=C3)O)CCC(=O)O)CCC(=O)N)N)C(=O)N[C@@H](CCCCN)C(=O)N)[C@@H](C)CC)CC4=CC=C(C=C4)O)CCC(=O)O	IC50 = 50400 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B14NHR	N-(1-Phenylethyl)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine	Investigative	44586767	C25H21N5S	423.5	CC(C1=CC=CC=C1)NC2=NC=CC(=N2)/C=C/C3=C(N=C4N3C=CS4)C5=CC=CC=C5	IC50 = 84000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B18DEM	c[YYDEALEE]-NH2	Investigative	46831064	C46H61N9O17	1012	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CC(=O)O)CC2=CC=C(C=C2)O)CC3=CC=C(C=C3)O)C(=O)N)CCC(=O)O)CC(C)C	IC50 = 101000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B18EWX	(E/Z)-N-(4-(2-(6-Phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-yl)acetamide	Investigative	44586769	C19H15N5OS	361.4	CC(=O)NC1=NC=CC(=N1)/C=C/C2=C(N=C3N2C=CS3)C4=CC=CC=C4	IC50 = 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B18RWA	N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine	Investigative	5330188	C23H25ClN4O5	472.9	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=CC4=C3OCO4)Cl)OCCCN5CCOCC5	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B1C2UF	Cyclo[FYDEPLEbtA]-NH2	Investigative	44444796	C49H63N13O16	1090.1	CC(C)C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC2=CN(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)NC(=O)N1)CCC(=O)O)CC(=O)O)CC4=CC=C(C=C4)O)CC5=CC=CC=C5)N=N2)C(=O)N)CCC(=O)O	IC50 = 93000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B1JZB8	N-[4-(3-Ethynylanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525285	C26H26N6O	438.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC=CC(=C4)C#C	IC50 = 156300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B1M2TH	N4-(3-Bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008965	C22H22BrN5O3	484.3	COC1=CC(=CC(=C1OC)OC)CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B2CL6O	N-(3-Bromophenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887111	C19H13BrCl2N4	448.1	C1=CC(=CC(=C1)Br)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl	IC50 = 150900 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B2ZJ3E	4-(2-(1-Methyl-4-phenyl-1H-imidazol-5-yl)cyclopropyl)pyrimidin-2-amine	Investigative	44586929	C17H17N5	291.35	CN1C=NC(=C1C2CC2C3=NC(=NC=C3)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B3A9GH	(3r)-1-{2-[4-(4-Acetylphenyl)piperazin-1-Yl]-2-Oxoethyl}-N-(3-Chloro-4-Hydroxyphenyl)pyrrolidine-3-Carboxamide	Investigative	58985201	C25H29ClN4O4	485	CC(=O)C1=CC=C(C=C1)N2CCN(CC2)C(=O)CN3CC[C@H](C3)C(=O)NC4=CC(=C(C=C4)O)Cl	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B3D4VI	6-[(2,4-Dichlorophenyl)methyl]-4-N-(3-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886971	C19H14Cl2FN5	402.2	C1=CC(=CC(=C1)F)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 = 162900 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B3HI9C	(E/Z)-N-(4-(2-(6-Phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-yl)pivalamide	Investigative	44586770	C22H21N5OS	403.5	CC(C)(C)C(=O)NC1=NC=CC(=N1)/C=C/C2=C(N=C3N2C=CS3)C4=CC=CC=C4	IC50 = 96000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B3MWL2	N4-(3-Bromophenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008956	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B3QX6N	4-N-(3-Ethynylphenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525247	C21H18N6	354.4	C#CC1=CC(=CC=C1)NC2=NC(=NC3=C2C=C(N3)CCC4=CC=CC=N4)N	IC50 = 103100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B4AC8G	4-N-(3-Bromophenyl)-7-[(3,4,5-trimethoxyphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57384106	C22H22BrN5O3	484.3	COC1=CC(=CC(=C1OC)OC)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 = 156500 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B52FED	N-(3-Ethynylphenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887298	C22H18N4	338.4	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(N3)CCC4=CC=CC=C4	IC50 = 142300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B5P9HU	2-Amino-N-(1-methyl-4-phenyl-1H-imidazol-5-yl)pyrimidine-4-carboxamide	Investigative	44586900	C15H14N6O	294.31	CN1C=NC(=C1NC(=O)C2=NC(=NC=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B5RM0K	(4S,6R)-6-Bromo-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-triene-2,8-dione	Investigative	53316977	C19H25BrO5	413.3	C[C@H]1C[C@H](CC(=O)CCCCCC2=C(C(=CC(=C2)OC)O)C(=O)O1)Br	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B5UOP1	4-N-(3-Bromophenyl)-7-[(4-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394880	C19H15BrClN5	428.7	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=CC=C(C=C4)Cl	IC50 = 79900 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B68NOA	N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine	Investigative	5329009	C16H13ClFN3O2	333.74	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B6FPS1	4-N-(3-Bromophenyl)-7-[(2-methylphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57396646	C20H18BrN5	408.3	CC1=CC=CC=C1CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 = 129300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B7XZN5	(E/Z)-4-(2-(3-Phenylthiophen-2-yl)vinyl)pyrimidin-2-amine	Investigative	44586833	C16H13N3S	279.4	C1=CC=C(C=C1)C2=C(SC=C2)/C=C/C3=NC(=NC=C3)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B82GQV	Cyclo[KYDEPLEbtA]-NH2	Investigative	44444803	C45H65N13O15	1028.099	CC(C)C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC2=CN(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N1)CCC(=O)O)CC(=O)O)CC4=CC=C(C=C4)O)CCCCN)N=N2)C(=O)N)CCC(=O)O	IC50 = 162000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B8MF5X	N-(3-Bromophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887255	C20H17BrN4	393.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 = 129400 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B8SJ4Q	(E/Z)-N-Phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine	Investigative	44586768	C23H17N5S	395.5	C1=CC=C(C=C1)C2=C(N3C=CSC3=N2)/C=C/C4=NC(=NC=C4)NC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B8T1KO	7-Benzyl-4-N-(3-bromophenyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394879	C19H16BrN5	394.3	C1=CC=C(C=C1)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 = 99300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B92RNM	4-{(E)-2-[4-Phenyl-1-(2-pyrrolidin-1-ylethyl)-1H-imidazol-5-yl]vinyl}pyrimidin-2-amine	Investigative	44586896	C21H24N6	360.5	C1CCN(C1)CCN2C=NC(=C2/C=C/C3=NC(=NC=C3)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B98XBU	4-N-(3-Methyl-5-phenylimidazol-4-yl)pyrimidine-2,4-diamine	Investigative	44586898	C14H14N6	266.3	CN1C=NC(=C1NC2=NC(=NC=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B9IA6L	N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-(2-methoxyethoxy)cinnolin-4-amine	Investigative	6326408	C18H17ClFN3O3	377.8	COCCOC1=C(C=C2C(=C1)N=NC=C2NC3=C(C=C(C=C3)Cl)F)OC	IC50 = 63000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B9N8WV	N-(2-Aminopyrimidin-4-yl)-1-methyl-4-phenyl-1H-imidazole-5-carboxamide	Investigative	44586899	C15H14N6O	294.31	CN1C=NC(=C1C(=O)NC2=NC(=NC=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	B9Q4WV	4-N-(3-Bromophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	10047098	C19H17BrN6	409.3	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BA21TR	N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine	Investigative	5330196	C23H25ClN4O4	456.9	CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BAW04S	4-N-(3-Bromophenyl)-7-[(2,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394786	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=C(C=C(C=C4)Cl)Cl	IC50 = 138100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BBWJ97	2-Benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine	Investigative	3008958	C19H16BrN5	394.3	C1=CC=C(C=C1)CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BDL8X6	1-(2-Chlorophenyl)-3-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)urea	Investigative	44414659	C28H29ClN6OS	533.1	CN1CCN(CC1)CC2=CC3=C(C=C2)C4=NNC(=C4C3)C5=CC=C(S5)CNC(=O)NC6=CC=CC=C6Cl	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BE9C0U	N4-(2-Isopropylphenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46887039	C22H21Cl2N5	426.3	CC(C)C1=CC=CC=C1NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 = 163100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BEC69I	N4-(3-Bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008961	C20H18BrN5	408.3	CC1=CC=CC=C1CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BFB3R5	N-Methyl-4-[(E)-2-(6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)vinyl]pyrimidin-2-amine	Investigative	44587326	C18H15N5S	333.4	CNC1=NC=CC(=N1)/C=C/C2=C(N=C3N2C=CS3)C4=CC=CC=C4	IC50 = 77000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BFOR28	N-[4-[4-Fluoro-3-(trifluoromethyl)anilino]-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525287	C25H24F4N6O	500.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC(=C(C=C4)F)C(F)(F)F	IC50 = 189600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BH1MY2	Anilinoquinazoline deriv. 31	Investigative	5329029	C18H16ClFN4O3	390.8	COCC(=O)NC1=C(C=C2C(=C1)N=CN=C2NC3=C(C=C(C=C3)Cl)F)OC	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BHP35J	Geranin B	Investigative	44566353	C30H24O11	560.5	C1[C@@H]([C@H](OC2=C1C(=CC3=C2[C@@H]4[C@H]([C@](O3)(OC5=CC(=CC(=C45)O)O)C6=CC(=C(C=C6)O)O)O)O)C7=CC=C(C=C7)O)O	IC50 = 65000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BHP90Y	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Acetamido-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-amino-5-oxopentanoyl]amino]acetyl]amino]-N-[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide	Investigative	53318682	C60H100N22O14S	1385.6	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCSC)NC(=O)C	IC50 = 102700 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BIB1E3	4-(2-(1-Methyl-4-phenyl-1H-imidazol-5-ylamino)ethyl)pyrimidin-2-amine	Investigative	44586928	C16H18N6	294.35	CN1C=NC(=C1NCCC2=NC(=NC=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BJ9T1E	3-[(3S,6S,9S,12R,17R,20S,23S,26S,29S,32S,35S,38S)-12-Amino-17-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-26,32-bis(2-carboxyethyl)-9,35-bis(hydroxymethyl)-3-[(4-hydroxyphenyl)methyl]-23-(1H-imidazol-5-ylmethyl)-20-(2-methylsulfanylethyl)-2,5,8,11,19,22,25,28,31,34,37-undecaoxo-29-propan-2-yl-14,15-dithia-1,4,7,10,18,21,24,27,30,33,36-undecazabicyclo[36.3.0]hentetracontan-6-yl]propanoic acid	Investigative	137650005	C60H88N16O23S3	1497.6	CC(C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CO)CC3=CC=C(C=C3)O)CCC(=O)O)CO)N)C(=O)N[C@@H](CO)C(=O)N)CCSC)CC4=CN=CN4)CCC(=O)O	IC50 = 56000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BJR71S	(4S)-5-[[(2S)-1-Amino-1-oxopent-4-yn-2-yl]amino]-4-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-azido-2-phenylacetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoic acid	Investigative	73345638	C47H59N11O15	1018	CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC#C)C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](C3=CC=CC=C3)N=[N+]=[N-]	IC50 = 96000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BK2GQ1	N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide	Investigative	27666048	C21H20N2O3S	380.5	CN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BK72AZ	(E/Z)-4-(2-(2-Phenylthiophen-3-yl)vinyl)pyrimidin-2-amine	Investigative	44586868	C16H13N3S	279.4	C1=CC=C(C=C1)C2=C(C=CS2)/C=C/C3=NC(=NC=C3)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BKBE69	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Acetamido-4-methylsulfanylbutanoyl]amino]pent-4-enoyl]amino]-3-methylpentanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-amino-5-oxopentanoyl]amino]acetyl]amino]-N-[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopent-4-en-2-yl]pentanediamide	Investigative	53322631	C58H95N17O14S	1286.5	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC=C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC=C)NC(=O)[C@H](CCSC)NC(=O)C	IC50 = 61200 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BLGH87	N-(5-Chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine	Investigative	5330197	C24H27ClN4O4	470.9	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=CC4=C3OCO4)Cl)OCCCN5CCCCC5	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BLKE67	4-N-(3-Bromophenyl)-6-[(4-phenylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008960	C25H20BrN5	470.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CC3=CC4=C(N3)N=C(N=C4NC5=CC(=CC=C5)Br)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BLZ42H	4-[(E)-2-(6-Methylimidazo[2,1-b][1,3]thiazol-5-yl)ethenyl]pyrimidin-2-amine	Investigative	44587324	C12H11N5S	257.32	CC1=C(N2C=CSC2=N1)/C=C/C3=NC(=NC=C3)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BMP16I	Cyclo[GHQMFYYbtA]-NH2	Investigative	44444786	C51H63N15O11S	1094.2	CSCCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC2=CN(NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)N)CC3=CN=CN3)N=N2)C(=O)N)CC4=CC=C(C=C4)O)CC5=CC=C(C=C5)O)CC6=CC=CC=C6	IC50 = 121000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BNJM48	2,2-Dimethyl-N-[6-(2-pyridin-2-ylethyl)-4-[3-(trifluoromethyl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]propanamide	Investigative	71525286	C25H25F3N6O	482.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC=CC(=C4)C(F)(F)F	IC50 = 129600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BNV2R7	(4S,6Z)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,15,17-tetraene-2,8-dione	Investigative	49842779	C19H24O5	332.4	C[C@H]1C/C=C\\C(=O)CCCCCC2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BO92CT	N4-(4-Isopropylphenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46887038	C22H21Cl2N5	426.3	CC(C)C1=CC=C(C=C1)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 = 157000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BOE94S	5-[(4-Methylphenyl)thio]-9h-pyrimido[4,5-b]indole-2,4-diamine	Investigative	25218207	C17H15N5S	321.4	CC1=CC=C(C=C1)SC2=CC=CC3=C2C4=C(N=C(N=C4N3)N)N	IC50 = 160100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BOHV12	4-N-(3-Bromo-4-fluorophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525245	C19H16BrFN6	427.3	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Br)N	IC50 = 93600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BOKW86	2-[(E)-2-(6-Phenylimidazo[2,1-b][1,3]thiazol-5-yl)ethenyl]pyrimidin-4-amine	Investigative	44586829	C17H13N5S	319.4	C1=CC=C(C=C1)C2=C(N3C=CSC3=N2)/C=C/C4=NC=CC(=N4)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BP61CA	(4S)-4-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-Amino-2-azidohexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S)-1-amino-1-oxopent-4-yn-2-yl]amino]-5-oxopentanoic acid	Investigative	73351741	C45H64N12O15	1013.1	CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC#C)C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CCCCN)N=[N+]=[N-]	IC50 = 151000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BP7XF8	3-[(3S,6S,9S,12S,21S,24S,27S,30S,33S,36S,39S,42S)-12-Acetamido-9-(3-amino-3-oxopropyl)-24,33-bis[(2S)-butan-2-yl]-30,36-bis(2-carboxyethyl)-39-(carboxymethyl)-21-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-3,27-bis[(4-hydroxyphenyl)methyl]-2,5,8,11,18,23,26,29,32,35,38,41-dodecaoxo-1,4,7,10,17,22,25,28,31,34,37,40-dodecazabicyclo[40.3.0]pentatetracontan-6-yl]propanoic acid	Investigative	137639956	C78H115N17O26	1706.8	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CC(=O)O)CC3=CC=C(C=C3)O)CCC(=O)O)CCC(=O)N)NC(=O)C)C(=O)N[C@@H](CCCCN)C(=O)N)[C@@H](C)CC)CC4=CC=C(C=C4)O)CCC(=O)O	IC50 = 75100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BPLH59	4-N-(3-Bromophenyl)-7-[(3,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57398331	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=CC(=C(C=C4)Cl)Cl	IC50 = 118600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BQ1AM8	(4S,6E,12E)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione	Investigative	49842666	C19H22O5	330.4	C[C@H]1C/C=C/C(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 = 51000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BQ9Y5W	2-[9-(4-Amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)acetamide	Investigative	44427518	C32H31N5O4	549.6	COC1=C(C=CC(=C1)C2=CC3=C(C=C2)C(=O)NC4=C(N3)C=CC(=C4)CC(=O)NC5=CC=C(C=C5)N6CCOCC6)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BQH90J	4-N-(3-Bromophenyl)-7-(naphthalen-1-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394787	C23H18BrN5	444.3	C1=CC=C2C(=C1)C=CC=C2CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 = 150000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BR79GT	3-[(3S,6S,9S,12S,15R,20R,23S,26S,29S,32S,35S,38S,41S)-15-Amino-9-(3-amino-3-oxopropyl)-12-benzyl-23,32-bis[(2S)-butan-2-yl]-29,35-bis(2-carboxyethyl)-38-(carboxymethyl)-20-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-3,26-bis[(4-hydroxyphenyl)methyl]-2,5,8,11,14,22,25,28,31,34,37,40-dodecaoxo-17,18-dithia-1,4,7,10,13,21,24,27,30,33,36,39-dodecazabicyclo[39.3.0]tetratetracontan-6-yl]propanoic acid	Investigative	137643789	C80H113N17O25S2	1777	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CC(=O)O)CC3=CC=C(C=C3)O)CCC(=O)O)CCC(=O)N)CC4=CC=CC=C4)N)C(=O)N[C@@H](CCCCN)C(=O)N)[C@@H](C)CC)CC5=CC=C(C=C5)O)CCC(=O)O	IC50 = 157400 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BS74TN	4-[(E)-2-(2-Phenylimidazo[1,2-a]pyridin-3-yl)vinyl]pyrimidin-2-amine	Investigative	44586834	C19H15N5	313.4	C1=CC=C(C=C1)C2=C(N3C=CC=CC3=N2)/C=C/C4=NC(=NC=C4)N	IC50 = 79000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BS9TZ1	N-[4-Fluoro-3-(trifluoromethyl)phenyl]-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887348	C21H16F4N4	400.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=C(C=C4)F)C(F)(F)F	IC50 = 164300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BSC93W	(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Acetamido-4-methylsulfanylbutanoyl]amino]pent-4-enoyl]amino]-3-methylpentanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]acetyl]amino]-N-[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopent-4-en-2-yl]pentanediamide	Investigative	53325256	C53H87N15O12S	1158.4	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CC=C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC=C)NC(=O)[C@H](CCSC)NC(=O)C	IC50 = 90300 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BU4S0J	4-[(E)-2-(4-Phenyl-1H-imidazol-5-yl)vinyl]pyrimidin-2-amine	Investigative	44586869	C15H13N5	263.3	C1=CC=C(C=C1)C2=C(NC=N2)/C=C/C3=NC(=NC=C3)N	IC50 = 68000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BU53YX	N4-((1-Methyl-4-phenyl-1H-imidazol-5-yl)methyl)pyrimidine-2,4-diamine	Investigative	44586901	C15H16N6	280.33	CN1C=NC(=C1CNC2=NC(=NC=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BUKT02	4-[(E)-2-(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)ethenyl]pyrimidin-2-amine	Investigative	44587325	C11H8ClN5S	277.73	C1=CN=C(N=C1/C=C/C2=C(N=C3N2C=CS3)Cl)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BUMX69	(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-1-Acetylpyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid	Investigative	137645340	C62H84N16O16	1309.4	CC(C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H]5CCCN5C(=O)C	IC50 = 129500 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BUO4L7	4-[(E)-2-(6-Phenylimidazo[2,1-b][1,3]thiazol-5-yl)vinyl]pyrimidine	Investigative	44586794	C17H12N4S	304.4	C1=CC=C(C=C1)C2=C(N3C=CSC3=N2)/C=C/C4=NC=NC=C4	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BUPG71	4-N-(4-Chloro-2-fluorophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57395925	C21H19ClFN5O2	427.9	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 = 185600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BW27YB	4-[(E)-2-(1-Methyl-5-phenylimidazol-4-yl)ethenyl]pyrimidin-2-amine	Investigative	44586870	C16H15N5	277.32	CN1C=NC(=C1C2=CC=CC=C2)/C=C/C3=NC(=NC=C3)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BW3EI4	(2R,3S)-8-[(2S,4R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol	Investigative	71521862	C30H26O9	530.5	C1[C@H](C2=C(C=C(C=C2O[C@@H]1C3=CC=C(C=C3)O)O)O)C4=C(C=C(C5=C4O[C@@H]([C@H](C5)O)C6=CC=C(C=C6)O)O)O	IC50 = 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BW3S6G	6-[(2,4-Dichlorophenyl)methyl]-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886972	C20H14Cl2F3N5	452.3	C1=CC(=CC(=C1)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N)C(F)(F)F	IC50 = 156100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BW53EL	4-N-(3-Bromophenyl)-7-(naphthalen-2-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57396545	C23H18BrN5	444.3	C1=CC=C2C=C(C=CC2=C1)CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 = 50800 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BX30KU	4-N-(4-Chloro-2-fluorophenyl)-6-[(2,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886970	C19H13Cl3FN5	436.7	C1=CC(=C(C=C1Cl)Cl)CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 = 70900 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BX51DL	(3S,6S,9S,14S,17S,23S,26S,29S)-9-[[(2S)-2-Acetamido-4-methylsulfanylbutanoyl]amino]-3-(4-aminobutyl)-N-[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]-17,23-bis(3-amino-3-oxopropyl)-6-[(2S)-butan-2-yl]-26-(1H-imidazol-5-ylmethyl)-2,5,8,12,16,19,22,25,28-nonaoxo-1,4,7,11,15,18,21,24,27-nonazabicyclo[27.3.0]dotriacontane-14-carboxamide	Investigative	56656325	C55H90N18O15S	1275.5	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CC(=O)NC[C@@H](C(=O)N1)NC(=O)[C@H](CCSC)NC(=O)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N)CCC(=O)N)CCC(=O)N)CC3=CN=CN3)CCCCN	IC50 = 87600 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BX84HQ	4-N-(3-Bromophenyl)-6-[(3,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008964	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=NC(=NC3=C2C=C(N3)CC4=CC(=C(C=C4)Cl)Cl)N	IC50 ~ 50000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BY0PH8	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Acetamidopent-4-enoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-amino-5-oxopentanoyl]amino]acetyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxopent-4-en-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide	Investigative	53323499	C59H94N22O14	1335.5	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC3=CN=CN3)C(=O)N[C@@H](CC=C)C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC=C)NC(=O)C	IC50 = 76800 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BZ4F6B	5-[(E)-2-(2-Chloropyrimidin-4-yl)vinyl]-6-phenylimidazo[2,1-b][1,3]thiazole	Investigative	11724734	C17H11ClN4S	338.8	C1=CC=C(C=C1)C2=C(N3C=CSC3=N2)/C=C/C4=NC(=NC=C4)Cl	IC50 = 66000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BZ53FX	5-(Phenylthio)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	25181586	C16H13N5S	307.4	C1=CC=C(C=C1)SC2=CC=CC3=C2C4=C(N=C(N=C4N3)N)N	IC50 = 118100 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BZ7A5X	(E/Z)-4-(2-(4-Phenyl-1H-pyrazol-5-yl)vinyl)pyrimidin-2-amine	Investigative	44586832	C15H13N5	263.3	C1=CC=C(C=C1)C2=C(NN=C2)/C=C/C3=NC(=NC=C3)N	IC50 ~ 100000 nM	Poor binder
T63966	Vascular endothelial growth factor receptor 1	BZ9X0H	4-N-(3-Bromophenyl)-7-[(2-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57384105	C19H15BrClN5	428.7	C1=CC=C(C(=C1)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br)Cl	IC50 = 126300 nM	Poor binder