TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T64213 Transient receptor potential cation channel V4 B26CVM 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide Investigative 743974 C16H19NO3S 305.4 CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C EC50 ~ 125892.54 nM Poor binder T64213 Transient receptor potential cation channel V4 BG5RW0 (R)-8-{5-[3-Methyl-4-(trifluoromethyl)phenyl]oxazol-2-ylamino}-1,2,3,4-tetrahydronaphthalen-2-ol Investigative 25270198 C21H19F3N2O2 388.4 CC1=C(OC(=N1)NC2=CC=CC3=C2C[C@@H](CC3)O)C4=CC=C(C=C4)C(F)(F)F IC50 ~ 100000 nM Poor binder