TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	D0Z5DM	IMD-0354	Phase 1	5081913	C15H8ClF6NO2	383.67	C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B08AYZ	3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575127	C21H17N3O2S	375.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CSC=C4	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B0A8LD	4-(4-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	17229016	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC=C(C=C2)Br	IC50 = 89700 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B0VRX8	Chembl4286561	Investigative	145990026	C17H17N3O	279.34	CC1=C(C(=NN1)N)C2=CC=C(C=C2)OCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B1ECY3	4-(3-Chlorophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	12330558	C10H10ClN3	207.66	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B23JHS	Chembl4281464	Investigative	43157763	C10H9Cl2N3	242.1	CC1=C(NN=C1N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B26XDG	Chembl4280454	Investigative	62900145	C12H15N3	201.27	CC1=C(C=C(C=C1)C2=C(NN=C2N)C)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B28TJX	Chembl4292701	Investigative	145989643	C16H12Cl2N4O	347.2	CC1=C(C(=NN1C(=O)C2=CN=CC=C2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B2ET5J	Chembl4284888	Investigative	145991715	C13H13Cl2N3O	298.16	CCC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B2GND6	3-Methyl-4-(3-methylphenyl)-1H-pyrazol-5-amine	Investigative	25219675	C11H13N3	187.24	CC1=CC(=CC=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B2J7OE	Chembl4283909	Investigative	61992815	C10H9Cl2N3	242.1	CC1=C(C(=NN1)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B30JVC	8-Methoxy-12-methyl-4-phenyl-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaene	Investigative	20823998	C16H13N3OS	295.4	CC1=CN=C2N1C3=C(C=C(S3)C4=CC=CC=C4)N=C2OC	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B3T9QN	Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44219749	C24H29N7O5	495.5	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B4DR3P	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(diethylamino)ethyl]benzamide	Investigative	49865328	C23H30N6O	406.5	CCN(CC)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B4G2QZ	Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605035	C22H27N7O3	437.5	COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B4XPM8	Chembl4284120	Investigative	145992355	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC(=CC=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B53QDN	Chembl4294749	Investigative	145993951	C12H7F6N3O2S	371.26	COC1=NSN=C1C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B5HDA2	Chembl4279494	Investigative	145980076	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NON=C2N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B5QDZ2	Chembl4288356	Investigative	145991401	C14H13N3	223.27	CC1=C(C(=NN1)N)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B61MIW	Chembl4288275	Investigative	145991182	C14H13Cl2N3O	310.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CC3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B64GVF	Chembl4280373	Investigative	145979893	C14H15Cl2N3O	312.2	CCCC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B6PEN8	3-Methyl-4-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine	Investigative	2782960	C11H10F3N3	241.21	CC1=C(C(=NN1)N)C2=CC(=CC=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B78QCH	7-(1-(4-Chlorobenzyl)piperidin-3-yl)-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide	Investigative	53321248	C23H25ClN6O2S	485	C1CC(CN(C1)CC2=CC=C(C=C2)Cl)N3C=C4C(=N3)CCC5=C4SC(=C5C(=O)N)NC(=O)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B7A8XY	Chembl4284415	Investigative	82482456	C11H11Cl2N3	256.13	CC1=C(C(=NN1C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B7MO4E	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide	Investigative	24959046	C21H26N6O	378.5	CN(C)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B87KWG	3-(5-Fluoro-6-Iodo-1-Methyl-1h-Indol-3-Yl)-4-(7-Methoxy-1-Benzofuran-3-Yl)-1h-Pyrrole-2,5-Dione	Investigative	24825779	C22H14FIN2O4	516.299	CN1C=C(C2=CC(=C(C=C21)I)F)C3=C(C(=O)NC3=O)C4=COC5=C4C=CC=C5OC	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B8DQ3O	Chembl4286012	Investigative	145993088	C15H17Cl2N3O2	342.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)OC(C)(C)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B8WX4N	Chembl4284828	Investigative	145992596	C15H15Cl2N3O	324.2	CC1=C(C(=NN1C(=O)C2CCC2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B8XG9W	3-{[(1R)-1-Phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	Investigative	15295578	C17H15N3O2	293.32	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B9RCI4	2-(2,6-Dichloro-phenylamino)-7-(3-diethylamino-propenyl)-1,6-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one	Investigative	9869943	C25H27Cl2N5O	484.4	CCN(CC)C/C=C/C1=C(C2=C(C3=C(C=C2)N=C(N3C)NC4=C(C=CC=C4Cl)Cl)C(=O)N1)C	IC50 = 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B9T0GB	3-Methyl-4-phenyl-1H-pyrazol-5-amine	Investigative	599501	C10H11N3	173.21	CC1=C(C(=NN1)N)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	B9WLO4	Chembl4292088	Investigative	145989390	C12H9F6N3	309.21	CC1=C(C(=NN1)N)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BA62QX	4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	24766030	C24H21N5OS	427.5	CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BAWF21	Chembl4294725	Investigative	145993662	C13H12F3N3O	283.25	CC1=NN(C(=C1C2=CC(=CC=C2)C(F)(F)F)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BBW1V3	Chembl4287493	Investigative	145990918	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BC9D0M	7-(1-(2-Fluoro-4-methoxybenzyl)piperidin-3-yl)-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide	Investigative	53321249	C24H27FN6O3S	498.6	COC1=CC(=C(C=C1)CN2CCCC(C2)N3C=C4C(=N3)CCC5=C4SC(=C5C(=O)N)NC(=O)N)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BD16SE	2-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)benzoic acid	Investigative	44406506	C19H13N3O2S	347.4	C1=CC=C2C(=C1)C=C(S2)C3=NC(=NC=C3)NC4=CC=CC=C4C(=O)O	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BD26PF	Chembl4295066	Investigative	145993626	C6H8BrN3O	218.05	CC1=C(C(=NN1C(=O)C)N)Br	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BE30YH	3-(7-(4-((1S,4S)-5-Methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol	Investigative	46880136	C29H26N6O	474.6	CN1C[C@@H]2C[C@H]1CN2C3=CC=C(C=C3)C4=CC=NC5=C(C(=NN45)C6=CC=NC=C6)C7=CC(=CC=C7)O	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BE6P2G	Chembl4290916	Investigative	145987124	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BESX34	Chembl4291313	Investigative	145988918	C13H13Cl2N3O	298.16	CCC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BF50KG	Chembl4280665	Investigative	145981483	C14H17N3O	243.3	CC1=C(C=C(C=C1)C2=C(N(N=C2C)C(=O)C)N)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BG51KO	Chembl4284710	Investigative	145991710	C11H5F6N3O2S	357.23	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BG5CM0	7-(1-(2,4-Difluorobenzyl)piperidin-3-yl)-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide	Investigative	51346795	C23H24F2N6O2S	486.5	C1CC(CN(C1)CC2=C(C=C(C=C2)F)F)N3C=C4C(=N3)CCC5=C4SC(=C5C(=O)N)NC(=O)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BHR4O6	4-(4-Chlorophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	575802	C10H10ClN3	207.66	CC1=C(C(=NN1)N)C2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BIKV80	3-[[2-(2-Fluorophenyl)pyridin-4-yl]amino]-4-[[(1R)-1-phenylethyl]amino]cyclobut-3-ene-1,2-dione	Investigative	44575073	C23H18FN3O2	387.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CC=C4F	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BJ4D0E	Chembl4290266	Investigative	145989760	C14H11F6N3O2	367.25	CC1=C(C(=O)NN1C)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BK1V8Q	3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575126	C21H17N3O3	359.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BK5IC4	Chembl4288230	Investigative	145992947	C6H8BrN3O	218.05	CC1=NN(C(=C1Br)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BK7CG0	4-(3-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	43560957	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Br	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BKJF41	Chembl4291690	Investigative	145987159	C16H17Cl2N3O	338.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCCC3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BKY2B1	Chembl4280067	Investigative	145981688	C12H8F6N4O2	354.21	CN1C(=C(N=N1)O)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BMB6O4	7-(1-Benzylpiperidin-3-yl)-2-(carbamoylamino)-4,5-dihydrothieno[2,3-e]indazole-3-carboxamide	Investigative	53325187	C23H26N6O2S	450.6	C1CC(CN(C1)CC2=CC=CC=C2)N3C=C4C(=N3)CCC5=C4SC(=C5C(=O)N)NC(=O)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BMEF20	Chembl4286341	Investigative	145992014	C17H13Cl2N3O	346.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BMP0C7	Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605037	C25H33N7O3	479.6	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BN2IC3	4-Tert-Butyl-N-[2-Methyl-3-(6-{[4-(Morpholin-4-Ylcarbonyl)phenyl]amino}-7h-Purin-2-Yl)phenyl]benzamide	Investigative	53356518	C34H35N7O3	589.7	CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=NC4=C(C(=N3)NC5=CC=C(C=C5)C(=O)N6CCOCC6)NC=N4	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BNHC98	2-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}-2-phenylacetamide	Investigative	25206064	C17H14N4O3	322.32	C1=CC=C(C=C1)C(C(=O)N)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BNUA75	Chembl4291646	Investigative	61992242	C11H11Cl2N3	256.13	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BO7XJ5	3-Methyl-4-(4-methylphenyl)-1H-pyrazol-5-amine	Investigative	24219848	C11H13N3	187.24	CC1=CC=C(C=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BPN6A8	4-(2H-1,3-Benzodioxol-5-yl)-5-methyl-1H-pyrazol-3-amine	Investigative	43157843	C11H11N3O2	217.22	CC1=C(C(=NN1)N)C2=CC3=C(C=C2)OCO3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BQ7SJ6	Chembl4278086	Investigative	145979124	C13H14Cl2N4O	313.18	CCNC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BS9T2K	Chembl4283501	Investigative	145992122	C12H8F6N4O2	354.21	CN1NC(=O)C(=N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BTO21Q	Chembl4287264	Investigative	145991820	C17H11ClN4O	322.7	C1=CC(=CN=C1)C(=O)NC2=CC3=C(C4=C(N3)C=NC=C4)C(=C2)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BUNM27	Chembl4283080	Investigative	145981824	C13H9F6N3O2	353.22	CN1C=C(C(=O)N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BV08KQ	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[1-(dimethylamino)propan-2-yl]benzamide	Investigative	49865330	C22H28N6O	392.5	CC(CN(C)C)NC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BV56JS	Chembl4287399	Investigative	145990465	C17H19Cl2N3O	352.3	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BVD8E1	Chembl4283832	Investigative	145990988	C15H15Cl2N3O	324.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCC3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BVJ41C	Chembl4279585	Investigative	145980083	C14H14ClN3O	275.73	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C3CC3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BVT56Q	Chembl4277586	Investigative	145984375	C12H11Cl2N3O	284.14	CC1=C(C(=NN1C(=O)C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BW4N7G	Chembl4287256	Investigative	145991367	C11H5F6N3O3	341.17	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BW7J3F	Chembl4282760	Investigative	145979774	C11H10F3N3O	257.209	CC1=C(C(=NN1)N)C2=CC(=CC=C2)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BX2T9M	Chembl4281003	Investigative	145981500	C16H12Cl2N4O	347.2	CC1=C(C(=NN1)NC(=O)C2=CC=CC=N2)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BXG7C1	Chembl4293673	Investigative	145987461	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NNNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BZ4KV5	Chembl4177097	Investigative	145971744	C10H6F3N3O3	273.17	C1=CC(=CC(=C1)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	BZI24E	Chembl4283047	Investigative	145980681	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	D01YWE	PMID19364658C33	Investigative	25207521	C17H14N4O4	338.32	C1=CC(=CC(=C1)O)C(C(=O)N)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65879	Inhibitor of nuclear factor kappa-B kinase alpha	D0LE7J	PMID23374866C31	Investigative	58221375	C20H22N4O3	366.4	CC(C)(C#CC1=CC2=C(C=C1)NC=C2C3=NC(=NC=C3OCCOC)N)O	IC50 ~ 100000 nM	Poor binder