TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T66665	Prostaglandin G/H synthase 2	D00IBN	Piroxicam	Approved	54676228	C15H13N3O4S	331.3	CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3	IC50 = 89125.09 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0GY5Z	Aspirin	Approved	2244	C9H8O4	180.16	CC(=O)OC1=CC=CC=C1C(=O)O	Ki = 52000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0U5QK	Acetaminophen	Approved	1983	C8H9NO2	151.16	CC(=O)NC1=CC=C(C=C1)O	IC50 = 141000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D00QOF	ORG-13011	Phase 2	44473151	C38H43N3O4S	637.8	CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)O)SC(C)(C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D05FGR	R-flurbiprofen	Phase 2	92337	C15H13FO2	244.26	C[C@H](C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O	IC50 = 123000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0DK4I	PMID26560530-Compound-24	Patented	4534	C18H22O4	302.4	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0M6LX	N-(naphthylamino)-benzoate derivative 1	Patented	56851703	C17H12N2O4	308.29	C1=CC=C2C(=C1)C(=CC=C2[N+](=O)[O-])NC3=CC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0O4QB	EUGENOL	Patented	3314	C10H12O2	164.2	COC1=C(C=CC(=C1)CC=C)O	IC50 = 129000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0SG9Q	US9388139, 12	Patented	60194756	C20H20Cl2N2O2	391.3	CC(C)(C)C1=NN(C(C1)C2=C(C=C(C=C2)Cl)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D07HBI	ZD-2138	Discontinued in Phase 2	132306	C23H24FNO4	397.4	CN1C2=C(C=CC1=O)C=C(C=C2)COC3=CC(=CC(=C3)C4(CCOCC4)OC)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0K2ER	MK-886	Discontinued in Phase 2	3651377	C27H34ClNO2S	472.1	CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl	IC50 = 58000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B01YEX	[(1S,2S,6R,10S,11R,13S,14R,15R)-1,6-Dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-14-[(E)-2-methylbut-2-enoyl]oxy-5,9-dioxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,7-dienyl] 2-methylbutanoate	Investigative	118727931	C30H40O9	544.6	CCC(C)C(=O)O[C@@]12[C@@H](C1(C)C)[C@@H]3C(=O)C(=C[C@]4([C@H]([C@]3([C@@H]([C@H]2OC(=O)/C(=C/C)/C)C)O)C=C(C4=O)C)O)CO	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B02SYO	(Z)-4-Amino-4-(5-chlorofuran-2-yl)-3-phenylbut-3-en-2-one	Investigative	71682135	C14H12ClNO2	261.7	CC(=O)/C(=C(/C1=CC=C(O1)Cl)\\N)/C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B05EOI	4-(4-(Methylsulfonyl)phenyl)-5-phenyl-3H-1,2-dithiol-3-one	Investigative	44564048	C16H12O3S3	348.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SSC2=O)C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B08WRE	3-Amino-N-[3-(trifluoromethyl)phenyl]benzamide	Investigative	2317371	C14H11F3N2O	280.24	C1=CC(=CC(=C1)N)C(=O)NC2=CC=CC(=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B09SVN	3-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	20115449	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(F)(F)F)NC(=O)C2=CC(=CC=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0A7ZF	1-Methyl-2-guanidino-5-[(Z)-3,5-di-tert-butyl-4-hydroxybenzylidene]-2-imidazolin-4-one	Investigative	11726707	C20H29N5O2	371.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C\\2/C(=O)N=C(N2C)N=C(N)N	IC50 = 81000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0AO4Z	(1E,4E)-1,5-Bis(4-pyrrolidin-1-ylphenyl)penta-1,4-dien-3-one	Investigative	88749792	C25H28N2O	372.5	C1CN(CC1)C2=CC=C(C=C2)/C=C/C(=O)/C=C/C3=CC=C(C=C3)N4CCCC4	IC50 = 69820 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0CF9Z	4,5-Bis(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione	Investigative	136036210	C15H10O2S3	318.4	C1=CC(=CC=C1C2=C(SSC2=S)C3=CC=C(C=C3)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0D8ZC	2,6-Di-tert-butyl-4-(5-methoxy-1,2,4-thiadiazol-3-yl)phenol	Investigative	135474341	C17H24N2O2S	320.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C2=NSC(=N2)OC	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0ERO2	N-[(2-Methylphenyl)methyl]-2-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-4-amine	Investigative	44456799	C20H18F3N3O2S	421.4	CC1=CC=CC=C1CNC2=NC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 174827.6 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0FLY1	2-[3-(4-Methoxyphenyl)-1-phenylpyrazol-4-yl]-5-phenyl-1,3,4-oxadiazole	Investigative	46934257	C24H18N4O2	394.4	COC1=CC=C(C=C1)C2=NN(C=C2C3=NN=C(O3)C4=CC=CC=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0HX8R	2-(6-Chloro-9H-carbazol-2-yl)-propionic acid 2-nitrooxy-ethyl ester	Investigative	44587411	C17H15ClN2O5	362.8	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)OCCO[N+](=O)[O-]	IC50 = 65000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0L9CV	Chembl4282434	Investigative	145979761	C23H16FNO4S	421.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(C=C3)F)C(=O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0PK3Z	Chembl4173747	Investigative	138542656	C30H36N2O11	600.6	COC1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(C=C3)OC)CC(=O)NCCCCC(=O)OC[C@@H]4[C@@H]([C@@H]([C@H](C(O4)O)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0TJ4F	N-(Methylsulfonyl)-N-(3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)-phenyl)methanesulfonamide	Investigative	49805305	C20H26N2O6S2	454.6	CS(=O)(=O)N(C1=CC(=CC=C1)OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0TS3K	2-(4-Fluoro-phenyl)-5-methanesulfonyl-3-(4-methanesulfonyl-phenyl)-thiophene	Investigative	44330530	C18H15FO4S3	410.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 = 200000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0U2PZ	N-(3-Phenylsulfinyl-4-pyridinyl)trifluoromethanesulfonamide	Investigative	11256603	C12H9F3N2O3S2	350.3	C1=CC=C(C=C1)S(=O)C2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B0XE2U	[3-[2-Fluoro-4-(1-hydroxypropan-2-yl)phenyl]phenyl] N-hexylcarbamate	Investigative	73054809	C22H28FNO3	373.5	CCCCCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)CO)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B13XFG	2-[6-Chloro-9-(methylcarbamoyl)carbazol-2-yl]propanoic acid	Investigative	71457026	C17H15ClN2O3	330.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)NC)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B14FJB	3-Mesityl-4-phenyl-5-methylisoxazole	Investigative	11231244	C19H19NO	277.4	CC1=CC(=C(C(=C1)C)C2=NOC(=C2C3=CC=CC=C3)C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B14JLX	2-(6-Chloro-9-methyl-9H-carbazol-2-yl)propanoic acid	Investigative	71462406	C16H14ClNO2	287.74	CC(C1=CC2=C(C=C1)C3=C(N2C)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B17GID	4-[3-(2-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548447	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B17LIW	4-[5-Tert-butyl-3-(2-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548633	C20H21FN2O2	340.4	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2F)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1BCO8	4-(2-(4-Fluorophenyl)-1H-pyrrol-1-yl)-N-methylbenzenesulfonamide	Investigative	10520447	C17H15FN2O2S	330.4	CNS(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1FH9Q	N-Caffeoyl serotonin	Investigative	16659826	C19H18N2O4	338.4	C1=CC(=C(C=C1/C=C/C(=O)NCCC2=CNC3=C2C=C(C=C3)O)O)O	Ki = 65500 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1GC2Y	2-(Benzenesulfonyl)-3-(1,3-benzodioxol-4-yl)-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706117	C17H13F3N2O4S	398.4	C1C(N(N=C1C(F)(F)F)S(=O)(=O)C2=CC=CC=C2)C3=C4C(=CC=C3)OCO4	IC50 = 60980 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1H2QN	trans-AUCB	Investigative	16038368	C24H32N2O4	412.5	C1CC(CCC1NC(=O)NC23CC4CC(C2)CC(C4)C3)OC5=CC=C(C=C5)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1H3QL	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-phenylsulfanyl-thiophene	Investigative	44330495	C23H17FO2S3	440.6	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=C2)SC3=CC=CC=C3)C4=CC=C(C=C4)F	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1I9MY	Chembl4278979	Investigative	145980296	C18H14FNO5S	375.4	COC(=O)C1=C(C(=NO1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1JL3E	2-(4-Chlorophenyl)-4-(methylsulfonylmethyl)-1-(4-methylsulfonylphenyl)imidazole	Investigative	10670044	C18H17ClN2O4S2	424.9	CS(=O)(=O)CC1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1L9XT	3,5-Diphenyl-1,2-oxazole-4-carboxylic acid	Investigative	13804275	C16H11NO3	265.26	C1=CC=C(C=C1)C2=C(C(=NO2)C3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1N7AP	2-[6-Chloro-9-[(2-methoxyphenyl)methyl]carbazol-2-yl]propanoic acid	Investigative	71458882	C23H20ClNO3	393.9	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC=CC=C4OC)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1NG7J	Chembl4173674	Investigative	145949529	C20H19ClN6O2	410.9	C1COCC(=O)N1C2=CC=C(C=C2)NC3=NC(=NC(=N3)NCC4=CC=CC=C4)Cl	IC50 = 60000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1QF5G	(3E,5E)-3,5-Bis[(4-pyrrolidin-1-ylphenyl)methylidene]piperidin-4-one	Investigative	118706207	C27H31N3O	413.6	C1CN(CC1)C2=CC=C(C=C2)/C=C\\3/C(=O)/C(=C/C4=CC=C(C=C4)N5CCCC5)/CNC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1TKH3	4-[(3E,6E,9E,12E)-Pentadeca-3,6,9,12-tetraenyl]sulfanylbutanoic acid	Investigative	44584307	C19H30O2S	322.5	CC/C=C/C/C=C/C/C=C/C/C=C/CCSCCCC(=O)O	IC50 = 120000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1W5SP	4-[5-Tert-butyl-3-(3-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68308827	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1WLV8	N-[4-(4-Chloroanilino)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728408	C21H16ClN3O4S	441.9	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)NC4=CC=C(C=C4)Cl)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1XKC6	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(4-fluorophenyl)methanone;hydrochloride	Investigative	46845030	C34H37ClF2N2O5	627.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)F.Cl	IC50 = 53600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1XMA7	2-Bromo-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene	Investigative	44330429	C17H12BrFO2S2	411.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2C3=CC=C(C=C3)F)Br	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B1ZP8A	Acetic acid 2-ethylsulfanyl-phenyl ester	Investigative	9813036	C10H12O2S	196.27	CCSC1=CC=CC=C1OC(=O)C	IC50 = 200000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B21EIN	2-[4-[3-(Benzylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	73054547	C23H20FNO4	393.4	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NCC3=CC=CC=C3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B26CVM	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	Investigative	743974	C16H19NO3S	305.4	CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B26LDF	4-[[2-(4-Fluorophenyl)-4-oxo-1,3-thiazolidin-3-yl]amino]benzenesulfonamide	Investigative	70691164	C15H14FN3O3S2	367.4	C1C(=O)N(C(S1)C2=CC=C(C=C2)F)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 63000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B26WTR	4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-benzenesulfonamide	Investigative	11002614	C17H22N2O4S	350.4	CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)OC)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B28FJT	Methyl 5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate	Investigative	10738225	C17H14FN3O4S	375.4	COC(=O)C1=NN(C(=C1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B28LDQ	Schembl20646331	Investigative	137412863	C18H12F8O3S	460.3	C1=CC=C(C=C1)CC2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)S(F)(F)(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B29MZO	N-[3-(3-Bromo-4-hydroxyanilino)pyridin-4-yl]-1,1,1-trifluoromethanesulfonamide	Investigative	76310403	C12H9BrF3N3O3S	412.18	C1=CC(=C(C=C1NC2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F)Br)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2BC7E	3-[4-Methyl-1-(4-methylsulfonylphenyl)imidazol-2-yl]pyridine	Investigative	10663006	C16H15N3O2S	313.4	CC1=CN(C(=N1)C2=CN=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 79000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2BTZ5	(2R,3R)-6-[(E)-2-Carboxyethenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-1,4-benzodioxine-3-carboxylic acid	Investigative	57395427	C18H14O8	358.3	C1=CC2=C(C=C1/C=C/C(=O)O)O[C@H]([C@H](O2)C3=CC(=C(C=C3)O)O)C(=O)O	IC50 = 52600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2C0ZE	Methyl (2S)-4-methyl-2-[[2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]acetyl]amino]pentanoate	Investigative	127043218	C22H33N3O6	435.5	CC(C)C[C@@H](C(=O)OC)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1	IC50 = 56000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2CDW6	4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline	Investigative	49805303	C18H22N2O2	298.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2EC1Z	1,2-Dihydro-7-methoxy-3-(2,3,4-trimethoxyphenyl)-naphthalene	Investigative	23627031	C20H22O4	326.4	COC1=CC2=C(C=C1)C=C(CC2)C3=C(C(=C(C=C3)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2ETU0	5-[(5-Anilino-1,3,4-thiadiazol-2-yl)methyl]-3-methyl-7-[(4-nitrophenyl)methyl]-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70689657	C22H17N7O4S	475.5	CC1=NOC2=C1C(=O)N(N=C2CC3=CC=C(C=C3)[N+](=O)[O-])CC4=NN=C(S4)NC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2IO8D	3-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline	Investigative	49805302	C18H22N2O2	298.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2J3WI	2-[1-(4-Chloro-benzoyl)-5-methoxy-1H-indol-3-yl]-N-phenethyl-acetamide	Investigative	10718261	C26H23ClN2O3	446.9	COC1=CC2=C(C=C1)N(C=C2CC(=O)NCCC3=CC=CC=C3)C(=O)C4=CC=C(C=C4)Cl	IC50 ~ 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2K1DI	8-(4-Carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53316515	C18H10ClF3O5	398.7	C1=CC(=CC=C1C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2M7LF	1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrrole	Investigative	10809969	C18H13F4NO2S	383.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(N2C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2O8NX	2-(Benzenesulfonyl)-3-naphthalen-1-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706112	C20H15F3N2O2S	404.4	C1C(N(N=C1C(F)(F)F)S(=O)(=O)C2=CC=CC=C2)C3=CC=CC4=CC=CC=C43	IC50 = 67130 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2PUG6	6-Chloro-7-((2,6-dimethylpiperidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53319287	C19H21ClF3NO3	403.8	CC1CCCC(N1CC2=C(C=C3C=C(C(OC3=C2)C(F)(F)F)C(=O)O)Cl)C	IC50 = 62200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2Q4FY	2-(2,6-Dichloro-3-methylphenylamino)benzohydroxamic acid 4-nitrobenzyl ester	Investigative	11744262	C21H17Cl2N3O4	446.3	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)NOCC3=CC=C(C=C3)[N+](=O)[O-])Cl	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2QM5E	Indomethacin derivative, 21	Investigative	10505250	C27H27BrN2O2	491.4	CC1=C(C2=C(N1CC3=CC=C(C=C3)Br)C=CC(=C2)OC)CC(=O)NCCC4=CC=CC=C4	IC50 ~ 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2TON8	2-[3-Fluoro-4-[2-(hexylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	73055091	C22H26FNO4	387.4	CCCCCCNC(=O)OC1=CC=CC=C1C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2UI8R	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole	Investigative	15380227	C16H13FN2O2S	316.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=NN2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2V4YX	N-[3-(3-Chlorophenoxy)-4-pyridinyl]trifluoromethanesulfonamide	Investigative	11291135	C12H8ClF3N2O3S	352.72	C1=CC(=CC(=C1)Cl)OC2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2WEG7	3-(5-Chlorofuran-2-Yl)-5-Methyl-4-Phenyl-1,2-Oxazole	Investigative	10355223	C14H10ClNO2	259.69	CC1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2X8PC	(2E)-2-[(4-Pyrrolidin-1-ylphenyl)methylidene]-3,4-dihydronaphthalen-1-one	Investigative	90645132	C21H21NO	303.4	C1CCN(C1)C2=CC=C(C=C2)/C=C/3\\CCC4=CC=CC=C4C3=O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B2XCZ4	(E)-3-(4-Methylsulfonylphenyl)-2-[3-(4-propan-2-yloxyphenyl)phenyl]prop-2-enoic acid	Investigative	76309082	C25H24O5S	436.5	CC(C)OC1=CC=C(C=C1)C2=CC(=CC=C2)/C(=C\\C3=CC=C(C=C3)S(=O)(=O)C)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B37TYH	4-[[4-Oxo-2-[4-(trifluoromethyl)phenyl]-1,3-thiazolidin-3-yl]amino]benzenesulfonamide	Investigative	70689055	C16H14F3N3O3S2	417.4	C1C(=O)N(C(S1)C2=CC=C(C=C2)C(F)(F)F)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 51800 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3CLD7	4-[5-(4-Hydroxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	135532444	C16H12F3N3O3S	383.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3CXD5	4-Amino-N-[3-(trifluoromethyl)phenyl]benzamide	Investigative	2756535	C14H11F3N2O	280.24	C1=CC(=CC(=C1)NC(=O)C2=CC=C(C=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3F0NS	4-[5-(4-Methoxyphenyl)tetrazol-1-yl]benzenesulfonamide	Investigative	57390392	C14H13N5O3S	331.35	COC1=CC=C(C=C1)C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3H6NO	4-(5-Tert-butyl-3-phenyl-3,4-dihydropyrazol-2-yl)benzoic acid	Investigative	68292820	C20H22N2O2	322.4	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3KW9B	6-(4-Methanesulfonyl-phenyl)-5-phenyl-2-trifluoromethyl-thiazolo[3,2-b][1,2,4]triazole	Investigative	44371442	C18H12F3N3O2S2	423.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC3=NC(=NN23)C(F)(F)F)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3L9PX	2-Phenylethyl 2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate	Investigative	10648828	C27H26BrNO3	492.4	CC1=C(C2=C(N1CC3=CC=C(C=C3)Br)C=CC(=C2)OC)CC(=O)OCCC4=CC=CC=C4	IC50 ~ 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3LT5J	4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805050	C17H20N2O2	284.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3MEY9	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine	Investigative	49805055	C16H19N3O2	285.34	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=NC=CN=C3	IC50 = 61600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3NCX5	5-Amino-N-[4-(trifluoromethyl)phenyl]pyridine-2-carboxamide	Investigative	24854032	C13H10F3N3O	281.23	C1=CC(=CC=C1C(F)(F)F)NC(=O)C2=NC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3OUB7	1-(4-Methylsulfonylphenyl)-5-(4-nitrophenyl)tetrazole	Investigative	57402675	C14H11N5O4S	345.34	CS(=O)(=O)C1=CC=C(C=C1)N2C(=NN=N2)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 = 69000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3QB0G	2,6-Bis(4-(pyrrolidin-1-yl)benzylidene)cyclohexanone	Investigative	118706205	C28H32N2O	412.6	C1CN(CC1)C2=CC=C(C=C2)/C=C\\3/C(=O)/C(=C/C4=CC=C(C=C4)N5CCCC5)/CCC3	IC50 = 54320 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3QN4W	(7-Tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-(4,5-dihydro-pyrazol-1-yl)-amine	Investigative	44344893	C17H25N3O	287.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)NN3CCC=N3)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B3S2RA	2-[6-Chloro-9-(4-fluorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71457021	C22H15ClFNO3	395.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=C(C=C4)F)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B40XZF	5-(4-(Methylsulfonyl)phenyl)-1-phenyl-1H-tetrazole	Investigative	53320894	C14H12N4O2S	300.34	CS(=O)(=O)C1=CC=C(C=C1)C2=NN=NN2C3=CC=CC=C3	IC50 = 200000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B42DXU	3,3-Dimethyl-5-[pyrrolizino(imino)methyl]-7-tert-butyl-2,3-dihydrobenzofuran	Investigative	10637982	C19H28N2O	300.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)C(=N)N3CCCC3)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B42HPU	1-(4-Chlorophenyl)-5-(4-(methylsulfonyl)phenyl)-1H-tetrazole	Investigative	53318243	C14H11ClN4O2S	334.8	CS(=O)(=O)C1=CC=C(C=C1)C2=NN=NN2C3=CC=C(C=C3)Cl	IC50 = 110000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B43SPG	Clematichinenoside C	Investigative	49799271	C70H114O34	1499.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B43WXO	4-[5-(4-Fluorophenyl)tetrazol-1-yl]benzenesulfonamide	Investigative	57392194	C13H10FN5O2S	319.32	C1=CC(=CC=C1C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 = 56000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B45HNP	US9271961, Bmt 4-90	Investigative	124222779	C14H12N2O5	288.25	COC1=CC(=C(C=C1)[N+](=O)[O-])NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B47SGK	Mofezolac	Investigative	4237	C19H17NO5	339.3	COC1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(C=C3)OC)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4A8KI	4-(3-Methoxy-5-phenyl-pyrazol-1-yl)-benzenesulfonamide	Investigative	10853804	C16H15N3O3S	329.4	COC1=NN(C(=C1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4BH3D	12-O-Tiglylphorbol-13-isobutyrate	Investigative	73350378	C29H40O8	516.6	C/C=C(\\C)/C(=O)O[C@@H]1[C@H]([C@]2([C@@H](C=C(C[C@]3([C@H]2C=C(C3=O)C)O)CO)[C@H]4[C@@]1(C4(C)C)OC(=O)C(C)C)O)C	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4EW3S	N-Methyl-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805307	C20H26N2O4S	390.5	CN(C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 = 92000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4FC8U	6-Chloro-7-((isopropyl(methyl)amino)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53325872	C16H17ClF3NO3	363.76	CC(C)N(C)CC1=C(C=C2C=C(C(OC2=C1)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4FCR7	N-[4-[(Z)-2-Cyclohexyl-1,2-diphenylethenyl]phenyl]methanesulfonamide	Investigative	76312773	C27H29NO2S	431.6	CS(=O)(=O)NC1=CC=C(C=C1)/C(=C(/C2CCCCC2)\\C3=CC=CC=C3)/C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4G6MU	[1-(4-Chloro-benzoyl)-5-methoxy-1H-indol-3-yl]-acetic acid phenethyl ester	Investigative	10599548	C26H22ClNO4	447.9	COC1=CC2=C(C=C1)N(C=C2CC(=O)OCCC3=CC=CC=C3)C(=O)C4=CC=C(C=C4)Cl	IC50 ~ 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4HB0K	4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N,N-dimethyl-benzenesulfonamide	Investigative	10688810	C18H17FN2O2S	344.4	CN(C)S(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4I6QF	5-(2-Acetoxy-phenylsulfanyl)-pentanoic acid	Investigative	10516041	C13H16O4S	268.33	CC(=O)OC1=CC=CC=C1SCCCCC(=O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4K9MD	N-(3-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide	Investigative	24853947	C13H10F3N3O	281.23	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=C(C=CC=N2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4N1UE	1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole	Investigative	44307569	C19H17FN2O2S	356.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C=C2C3=CC=C(C=C3)F)CC=C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4OFC8	N-(4-Amino-2-pyridyl)-4-(trifluoromethyl)benzamide	Investigative	24854030	C13H10F3N3O	281.23	C1=CC(=CC=C1C(=O)NC2=NC=CC(=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4QC2Z	Methyl 2-[3-fluoro-4-[3-(hexylcarbamoyloxy)phenyl]phenyl]propanoate	Investigative	90036171	C23H28FNO4	401.5	CCCCCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)OC)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4SK0Y	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-phenylmethanone;hydrochloride	Investigative	46906729	C34H38ClFN2O5	609.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=CC=C6.Cl	IC50 = 78300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4TJI8	3,4-Bis-(4-methylsulfanyl-phenyl)-thiophene	Investigative	44330563	C18H16S3	328.5	CSC1=CC=C(C=C1)C2=CSC=C2C3=CC=C(C=C3)SC	IC50 = 101000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4WH0S	(R)-Carprofen	Investigative	6997572	C15H12ClNO2	273.71	C[C@H](C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4YQ8G	(2E,6Z)-2,6-Bis[[4-(dimethylamino)-2-nitrophenyl]methylidene]cyclohexan-1-one	Investigative	90645116	C24H26N4O5	450.5	CN(C)C1=CC(=C(C=C1)/C=C/2\\CCC/C(=C/C3=C(C=C(C=C3)N(C)C)[N+](=O)[O-])/C2=O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B4ZBX9	3-Morpholin-4-ylpropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate	Investigative	57780770	C21H21ClN2O5	416.9	C1COCCN1CCCOC(=O)C2=C(C(=NO2)C3=CC=C(O3)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B51GHP	2-[6-Chloro-9-(1,3-thiazole-4-carbonyl)carbazol-2-yl]propanoic acid	Investigative	71458879	C19H13ClN2O3S	384.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CSC=N4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B52ZWH	5-Chloro-3-(3-fluoro-4-phenylphenyl)-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	44310048	C24H16ClFO4S	454.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)C(=CO2)Cl)C3=CC(=C(C=C3)C4=CC=CC=C4)F	IC50 = 87902.25 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B53FJE	2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-spiro[4.5]dec-2-ene	Investigative	10810080	C23H25FO2S	384.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CC3(C2)CCCCC3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B57GXV	2-(4-Methylphenyl)sulfonyl-3-naphthalen-1-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706118	C21H17F3N2O2S	418.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=CC=CC4=CC=CC=C43	IC50 = 89070 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5A6BG	3-(4-Methoxy-2-nitroanilino)benzoic acid	Investigative	43358934	C14H12N2O5	288.25	COC1=CC(=C(C=C1)NC2=CC=CC(=C2)C(=O)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5FX1D	4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide	Investigative	2950007	C22H21N3O3S	407.5	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5G4CO	N-(2-Aminophenyl)-4-(trifluoromethyl)benzamide	Investigative	572427	C14H11F3N2O	280.24	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5I4XW	Ketorolac tromethamine	Investigative	84003	C19H24N2O6	376.4	C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O	IC50 = 60500 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5KGW2	3-Amino-N-[4-(trifluoromethyl)phenyl]benzamide	Investigative	13609513	C14H11F3N2O	280.24	C1=CC(=CC(=C1)N)C(=O)NC2=CC=C(C=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5MJ8Q	4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68292588	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5Q7AT	2-(6-Chloro-9H-carbazol-2-yl)-N-(2-hydroxyethyl)propanamide	Investigative	16415139	C17H17ClN2O2	316.8	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)NCCO	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5SX3M	5-Methyl-4-phenyl-3-(2,4,6-trimethoxy-phenyl)-isoxazole	Investigative	11301795	C19H19NO4	325.4	CC1=C(C(=NO1)C2=C(C=C(C=C2OC)OC)OC)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5V9FC	4-[3-(4-Methanesulfonyl-phenyl)-thiophen-2-yl]-phenol	Investigative	44330592	C17H14O3S2	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=C(C=C3)O	IC50 = 86000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5W0LS	4-[(3R,3Ar,6R,6aR)-6-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol	Investigative	12309637	C20H22O6	358.4	COC1=C(C=CC(=C1)[C@H]2[C@H]3CO[C@H]([C@H]3CO2)C4=CC(=C(C=C4)O)OC)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5Y3TI	[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S,6S)-4-[(2S,3R,4S,5R)-5-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate	Investigative	49799273	C76H124O40	1677.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B5Y4WD	Chembl4278833	Investigative	145981172	C18H14FNO4S	359.4	CC(=O)C1=C(C(=NO1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B60SWZ	N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-3,4-dihydro-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	46880352	C21H16Cl2N2O4S	463.3	C1=CC=C2C(=C1)C(C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B62HPJ	2-[6-Chloro-9-[(4-chlorophenyl)methyl]carbazol-2-yl]propanoic acid	Investigative	71453516	C22H17Cl2NO2	398.3	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC=C(C=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B64JTA	4-[3-(3-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548631	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B67FMY	4-[5-(4-Nitrophenyl)tetrazol-1-yl]benzenesulfonamide	Investigative	57399159	C13H10N6O4S	346.32	C1=CC(=CC=C1C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6BWH4	(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]butanedioic acid	Investigative	57393176	C20H19FN2O7	418.4	C1=CC(=CC=C1C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)C2=CC=C(C=C2)F)O	IC50 = 110000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6ME9Q	N,N-Dimethyl-12-(S-valinoyl)-13-acetyl-4r-4-deoxyphorbol	Investigative	11526431	C29H43NO7	517.7	C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@@H]4CC(=C3)CO)C)O)OC(=O)C)OC(=O)[C@H](C(C)C)N(C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6N4MR	Chembl4279921	Investigative	145982141	C16H12FNO3S	317.3	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6OPT3	4-Chloro-5-(4-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid	Investigative	11795928	C16H11Cl2N3O4S	412.2	C1=CC(=CC=C1C2=C(C(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O)Cl)Cl	IC50 = 70000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6S5QU	N-(3-Phenylsulfonyl-4-pyridinyl)trifluoromethanesulfonamide	Investigative	11382984	C12H9F3N2O4S2	366.3	C1=CC=C(C=C1)S(=O)(=O)C2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6U7KM	1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-4-methyl-1H-imidazole	Investigative	10568417	C17H15FN2O2S	330.4	CC1=CN(C(=N1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6V3XK	1-(5-Chloro-1,3-benzoxazol-2-yl)-N-cyclopentylpiperidine-4-carboxamide	Investigative	71520910	C18H22ClN3O2	347.8	C1CCC(C1)NC(=O)C2CCN(CC2)C3=NC4=C(O3)C=CC(=C4)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6VRJ1	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)-1H-pyrrole-5-carbonitrile	Investigative	10449908	C18H13FN2O2S	340.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)C#N)C3=CC=C(C=C3)F	IC50 = 64400 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6WX8C	N-(4-Aminophenyl)-3-(trifluoromethyl)benzamide	Investigative	18543182	C14H11F3N2O	280.24	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=CC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6XGT4	N-(3,4-Dimethoxyphenyl)-1-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-carboxamide	Investigative	90654429	C27H28N4O7	520.5	COC1=CC=C(C=C1)N2C(=NC(=N2)C(=O)NC3=CC(=C(C=C3)OC)OC)C4=CC(=C(C(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6YRO1	Sodium;2-[2-(4-methylsulfanylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56672143	C22H23NaO3S	390.5	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)SC)C(=O)[O-].[Na+]	IC50 = 150000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B6ZDE5	(5Z)-2-[1-(6-Methoxynaphthalen-2-yl)ethyl]-5-[(4-phenylphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one	Investigative	118729078	C30H23N3O2S	489.6	CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C3=NN4C(=O)/C(=C/C5=CC=C(C=C5)C6=CC=CC=C6)/SC4=N3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B71CQZ	4-Phenyl-5-methyl-3-(5-methylfuran-2-yl)isoxazole	Investigative	44194811	C15H13NO2	239.27	CC1=CC=C(O1)C2=NOC(=C2C3=CC=CC=C3)C	IC50 = 68200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B72LPH	1-[1-[(2-Chlorophenyl)methyl]-2-oxopyridin-3-yl]-3-(3-ethylphenyl)urea	Investigative	52946883	C21H20ClN3O2	381.9	CCC1=CC(=CC=C1)NC(=O)NC2=CC=CN(C2=O)CC3=CC=CC=C3Cl	Ki ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B73AJR	(3E,5E)-3,5-Bis[(4-pyrrolidin-1-ylphenyl)methylidene]oxan-4-one	Investigative	118706206	C27H30N2O2	414.5	C1CN(CC1)C2=CC=C(C=C2)/C=C\\3/C(=O)/C(=C/C4=CC=C(C=C4)N5CCCC5)/COC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B73XWZ	5-(4-Methylphenyl)-1-(4-methylsulfonylphenyl)tetrazole	Investigative	57399160	C15H14N4O2S	314.4	CC1=CC=C(C=C1)C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 87000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B75MIO	(-)-Epiafzelechin	Investigative	443639	C15H14O5	274.27	C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC=C(C=C3)O)O	IC50 = 69700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B75WEK	Huzhangoside B	Investigative	49799269	C64H104O29	1337.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B79TIS	4-(2-(4-(Methylsulfonyl)phenyl)-1-phenylbut-1-enyl)phenol	Investigative	11485761	C23H22O3S	378.5	CC/C(=C(\\C1=CC=CC=C1)/C2=CC=C(C=C2)O)/C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B79YHC	4-Methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine	Investigative	10571870	C17H14F3N3O2S	381.4	CC1=C(C=NC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 54000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7C9XS	3-(5-Chlorofuran-2-yl)-4-(2-fluorophenyl)-5-methyl-1,2-oxazole	Investigative	44194812	C14H9ClFNO2	277.68	CC1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=CC=C3F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7DE4X	N-[4-(4-Chlorophenoxy)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728407	C21H15ClN2O5S	442.9	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)OC4=CC=C(C=C4)Cl)O	IC50 = 70000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7F0AP	Methyl 3-(5-chlorofuran-2-yl)-5-phenyl-1,2-oxazole-4-carboxylate	Investigative	57780779	C15H10ClNO4	303.69	COC(=O)C1=C(ON=C1C2=CC=C(O2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7H9JQ	4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N-methyl-benzenesulfonamide	Investigative	10834744	C17H13F4N3O2S	399.4	CNS(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7HJC0	Mulberrin	Investigative	5481958	C25H26O6	422.5	CC(=CCC1=C2C(=C(C=C1O)O)C(=O)C(=C(O2)C3=C(C=C(C=C3)O)O)CC=C(C)C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7IZV6	(S)-Methyl 2-(2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)acetate	Investigative	12951906	C16H22N2O5	322.36	CC(C)[C@@H](C(=O)NCC(=O)OC)NC(=O)OCC1=CC=CC=C1	IC50 = 75000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7JB2W	N-(4-Chlorophenyl)-1-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-carboxamide	Investigative	90654428	C25H23ClN4O5	494.9	COC1=CC=C(C=C1)N2C(=NC(=N2)C(=O)NC3=CC=C(C=C3)Cl)C4=CC(=C(C(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7LO6I	3-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548444	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7ML3F	N-(Methylsulfonyl)-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805304	C20H26N2O6S2	454.6	CS(=O)(=O)N(C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7MV3Q	[3-(5-Chlorofuran-2-yl)-4-phenylisoxazol-5-yl]carboxylic acid	Investigative	57780765	C14H8ClNO4	289.67	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7NMA6	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)pyrazine	Investigative	10735037	C17H13FN2O2S	328.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC=CN=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7P6VC	Chembl4281362	Investigative	145982402	C15H11FN2O3S	318.3	C1=CC(=CC=C1C2=NOC(=C2)C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 = 81200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7XQO0	3-Bromo-2-chloro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1H-pyrrole	Investigative	10342564	C17H12BrClFNO2S	428.7	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=C(N2)Cl)Br)C3=CC=C(C=C3)F	IC50 = 88000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7ZG0N	3-(4-Fluorophenyl)-5-iodo-2-(4-methylsulfonylphenyl)-1H-pyrrole	Investigative	11743998	C17H13FINO2S	441.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)I)C3=CC=C(C=C3)F	IC50 = 92300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B7ZGJ8	2-[3-Fluoro-4-(3-isopropylphenyl)phenyl]propanoic acid	Investigative	44336320	C18H19FO2	286.3	CC(C)C1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B82QYA	2-(9-Benzoyl-6-chlorocarbazol-2-yl)propanoic acid	Investigative	71458884	C22H16ClNO3	377.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=CC=C4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B82VUK	1-(5-Chloro-1,3-benzoxazol-2-yl)-N-[(1S,2S)-2-phenylmethoxycyclopentyl]piperidine-4-carboxamide	Investigative	71720415	C25H28ClN3O3	454	C1C[C@@H]([C@H](C1)OCC2=CC=CC=C2)NC(=O)C3CCN(CC3)C4=NC5=C(O4)C=CC(=C5)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B87WOC	N-(2-Aminophenyl)-3-(trifluoromethyl)benzamide	Investigative	572426	C14H11F3N2O	280.24	C1=CC=C(C(=C1)N)NC(=O)C2=CC(=CC=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B89HPQ	Chembl4160466	Investigative	145957891	C23H24ClN7O2	465.9	C1CN(CCN1C2=CC=CC=C2)C3=NC(=NC(=N3)NC4=CC=C(C=C4)N5CCOCC5=O)Cl	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8AC1J	4-[5-Tert-butyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548266	C21H24N2O3	352.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8AV3F	2-(4-Oxo-4H-1-benzopyran-3-ylmethyleneamino)benzoic acid	Investigative	44582833	C17H11NO4	293.27	C1=CC=C2C(=C1)C(=O)C(=CO2)C=NC3=CC=CC=C3C(=O)O	IC50 = 65720 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8CQB3	(+)-3,4,3',4'-Tetrahydroxy-9,7'alpha-epoxy-7alpha,9'-lactone	Investigative	16681478	C18H16O7	344.3	C1[C@H]2[C@@H]([C@H](O1)C3=CC(=C(C=C3)O)O)C(=O)O[C@@H]2C4=CC(=C(C=C4)O)O	IC50 = 90200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8D3MA	4-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	8566717	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(F)(F)F)NC(=O)C2=CC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8FR2U	1-(4-Methoxyphenyl)-N-methyl-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-carboxamide	Investigative	90654426	C20H22N4O5	398.4	CNC(=O)C1=NN(C(=N1)C2=CC(=C(C(=C2)OC)OC)OC)C3=CC=C(C=C3)OC	IC50 = 68200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8FWA5	5-(4-Methoxyphenyl)-1-(4-methylsulfonylphenyl)tetrazole	Investigative	57393944	C15H14N4O3S	330.4	COC1=CC=C(C=C1)C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8JFB1	N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-6-methoxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728423	C22H16Cl2N2O5S	491.3	COC1=CC2=C(C=C1)S(=O)(=O)NC(=C2O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8JV9Y	2-[6-Chloro-9-[(4-chlorophenyl)carbamoyl]carbazol-2-yl]propanoic acid	Investigative	71453517	C22H16Cl2N2O3	427.3	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)NC4=CC=C(C=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8LN2Z	2-Amino-N-[4-(trifluoromethyl)phenyl]benzamide	Investigative	10564674	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8MJ1R	2-[4-[3-(Cyclobutylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	90035911	C20H20FNO4	357.4	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NC3CCC3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8MSW5	2-(4-Fluoro-phenyl)-1-(3-methanesulfonyl-phenyl)-1H-pyrrole	Investigative	10710438	C17H14FNO2S	315.4	CS(=O)(=O)C1=CC=CC(=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8NAC4	2-[3-(Methoxymethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10669268	C19H17F3N2O3S	410.4	COCC1=CC(=CC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 68100 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8NHC9	4-Hydroxy-N-[4-(4-methylphenyl)phenyl]-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728428	C22H18N2O4S	406.5	CC1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=C(C4=CC=CC=C4S(=O)(=O)N3)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8PD7R	4-[3-(5-Chloro-furan-2-yl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide	Investigative	11382191	C14H11ClN2O4S	338.8	CC1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8QYV1	1-(3-Chloro-4-methanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10665504	C17H13ClFNO2S	349.8	CS(=O)(=O)C1=C(C=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8SGL7	4-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzonitrile	Investigative	10448879	C19H17NO2S	323.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC=C(C=C3)C#N	IC50 = 77900 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8V2LE	2-[3-Fluoro-5-(trifluoromethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10742264	C18H11F7N2O2S	452.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC(=C3)F)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8WD3T	Chembl4173819	Investigative	145951867	C20H19ClN6O2	410.9	CC1=CC=C(C=C1)NC2=NC(=NC(=N2)Cl)NC3=CC=C(C=C3)N4CCOCC4=O	IC50 = 70000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8X3PM	2-[3-Fluoro-4-[3-(4-phenylbutylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	73055093	C26H26FNO4	435.5	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NCCCCC3=CC=CC=C3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B8YRG4	4-[2-[3-(Trifluoromethyl)-4-fluorophenyl]-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10786241	C19H16F4O2S	384.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B90AZM	1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805051	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=CC=C1OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B93JUR	5-Acetyl-2-(3-carboxyanilino)benzoic acid	Investigative	56964583	C16H13NO5	299.28	CC(=O)C1=CC(=C(C=C1)NC2=CC=CC(=C2)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B96MIJ	7-Benzyl-5-[[5-(ethylamino)-1,3,4-thiadiazol-2-yl]methyl]-3-methyl-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70695977	C18H18N6O2S	382.4	CCNC1=NN=C(S1)CN2C(=O)C3=C(C(=N2)CC4=CC=CC=C4)ON=C3C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9BQK0	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)-5-(methylsulfonyl)-1H-pyrrole	Investigative	10000662	C18H16FNO4S2	393.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 = 92300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9CB4P	4-[5-Tert-butyl-3-(4-nitrophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548267	C20H21N3O4	367.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)[N+](=O)[O-])C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9DB2V	2-[2-(4-Methylsulfonylphenyl)phenyl]quinoline	Investigative	21223977	C22H17NO2S	359.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=NC4=CC=CC=C4C=C3	IC50 = 57000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9EKJ4	1,2,3,4-Tetrafluoro-5-(4-fluorophenyl)-6-(4-methylsulfonylphenyl)benzene	Investigative	11795129	C19H11F5O2S	398.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=C(C(=C2F)F)F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9EU3P	Methyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate	Investigative	57780764	C15H10ClNO4	303.69	COC(=O)C1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9EW6L	4-[5-(2-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548445	C24H22N2O4	402.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9EYG5	6-Chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53316516	C17H9ClF4O3	372.7	C1=CC(=CC=C1C2=CC(=CC3=C2OC(C(=C3)C(=O)O)C(F)(F)F)Cl)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9F0DI	2-[3-(4-Bromophenyl)-1-phenylpyrazol-4-yl]-5-(4-chlorophenyl)-1,3,4-oxadiazole	Investigative	90643444	C23H14BrClN4O	477.7	C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)Br)C4=NN=C(O4)C5=CC=C(C=C5)Cl	IC50 = 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9G0DM	2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-5-[(4-methylsulfonylphenyl)methyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;hydrochloride	Investigative	46845034	C35H42ClFN2O6S	673.2	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)CC6=CC=C(C=C6)S(=O)(=O)C.Cl	IC50 = 109200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9HJV1	3-Fluoro-4-[3-(hexylcarbamoyloxy)phenyl]benzoic acid	Investigative	127029897	C20H22FNO4	359.4	CCCCCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9I8KU	4-[5-(3-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68293474	C24H22N2O4	402.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC(=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9LCQ3	2-(1-((1-(Difluoromethyl)-6-oxo-1,2,5,6-tetrahydropyridin-3-yl)methyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid	Investigative	52946122	C19H20F2N2O4	378.4	CC1=C(C2=C(N1CC3=CCC(=O)N(C3)C(F)F)C=CC(=C2)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9MJ1F	1-(4-Fluoro-benzyl)-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10688742	C19H18FNO2S	343.4	CC1=CC=C(N1CC2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9NG5C	4-[5-Tert-butyl-3-(2-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548632	C20H21ClN2O2	356.8	CC(C)(C)C1=NN(C(C1)C2=CC=CC=C2Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9PBS0	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(2,4,6-trichlorophenyl)methanone;hydrochloride	Investigative	46906737	C34H35Cl4FN2O5	712.5	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=C(C=C(C=C6Cl)Cl)Cl.Cl	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9PO4E	1-[2,6-Ditert-butyl-4-[(Z)-2-(4-methylsulfonylphenyl)-1-phenylhex-1-enyl]phenyl]ethanone	Investigative	76327240	C35H44O3S	544.8	CCCC/C(=C(\\C1=CC=CC=C1)/C2=CC(=C(C(=C2)C(C)(C)C)C(=O)C)C(C)(C)C)/C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9R3XB	3-[3-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid	Investigative	122192741	C13H10F5NO2S	339.28	C1=CC(=CC(=C1)NC2=CC(=CC=C2)S(F)(F)(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9YD2X	1-(4-Methanesulfonyl-phenyl)-2-(2-methoxy-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10596883	C18H15F3N2O3S	396.4	COC1=CC=CC=C1C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	B9YWK4	N-Hydroxyethanesulfonamide	Investigative	78363	C2H7NO3S	125.15	CCS(=O)(=O)NO	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BA0KH5	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(2-fluorophenyl)methanone;hydrochloride	Investigative	46906733	C34H37ClF2N2O5	627.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=CC=C6F.Cl	IC50 = 126000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BA37NI	2-{[2-Nitro-5-(trifluoromethyl)phenyl]amino}benzoic acid	Investigative	45117711	C14H9F3N2O4	326.23	C1=CC=C(C(=C1)C(=O)O)NC2=C(C=CC(=C2)C(F)(F)F)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BA7GZ2	2-(2,6-Dichloro-3-methylphenylamino)benzohydroxamic acid benzyl ester	Investigative	24825638	C21H18Cl2N2O2	401.3	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)NOCC3=CC=CC=C3)Cl	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BABX61	6-Methoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9965352	C12H9F3O4	274.19	COC1=CC2=C(C=C1)OC(C(=C2)C(=O)O)C(F)(F)F	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BAL2J3	4-[5-Tert-butyl-2-(4-carboxyphenyl)-3,4-dihydropyrazol-3-yl]-3-methoxybenzoic acid	Investigative	129012347	C22H24N2O5	396.4	CC(C)(C)C1=NN(C(C1)C2=C(C=C(C=C2)C(=O)O)OC)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BAMX25	(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoic acid	Investigative	57391410	C19H19FN2O6	390.4	C1=CC(=CC=C1C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)C2=CC=C(C=C2)F)O	IC50 = 140000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BAZ69R	6-Chloro-5-ethoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53323225	C13H10ClF3O4	322.66	CCOC1=C(C=CC2=C1C=C(C(O2)C(F)(F)F)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB0M4S	4-[5-(2,5-Dichlorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10526904	C16H10Cl2F3N3O2S	436.2	C1=CC(=CC=C1N2C(=CC(=N2)C(F)(F)F)C3=C(C=CC(=C3)Cl)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB34NM	3-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-pyrrol-2-yl]-propionic acid	Investigative	10524261	C20H18FNO4S	387.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(N2C3=CC=C(C=C3)F)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB3EZ7	3-Methoxyacetaminophen	Investigative	3080594	C9H11NO3	181.19	CC(=O)NC1=CC(=C(C=C1)O)OC	IC50 = 138000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB3Y7L	3-(4-(Methylsulfonyl)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide	Investigative	50906487	C17H17N3O2S2	359.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NN(C(C2)C3=CC=CC=C3)C(=S)N	IC50 = 50310 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB4I2P	(R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid	Investigative	13148390	C15H20O3	248.32	C[C@H](C1=CC=C(C=C1)C[C@@H]2CCC[C@H]2O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB6L0K	2-[6-Chloro-9-[(3-methoxyphenyl)methyl]carbazol-2-yl]propanoic acid	Investigative	16098419	C23H20ClNO3	393.9	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC(=CC=C4)OC)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BB8HN9	1-[4,4-Diethyl-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene	Investigative	10022177	C22H25FO2S	372.5	CCC1(CC(=C(C1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)CC	IC50 = 65000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BBQ83Y	N-(3-Chloro-2-methylphenyl)-2-(2-oxochromen-4-yl)oxypropanamide	Investigative	71462077	C19H16ClNO4	357.8	CC1=C(C=CC=C1Cl)NC(=O)C(C)OC2=CC(=O)OC3=CC=CC=C32	IC50 = 74910 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC1QE2	[4,5-Bis(4-methoxyphenyl)-2-thiazolyl]-(4-methyl-1-piperazinyl)methanone	Investigative	196841	C23H25N3O3S	423.5	CN1CCN(CC1)C(=O)C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC	IC50 = 65000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC20IJ	1,1,1-Trifluoro-N-[3-(4-hydroxyanilino)pyridin-4-yl]methanesulfonamide	Investigative	76314063	C12H10F3N3O3S	333.29	C1=CC(=CC=C1NC2=C(C=CN=C2)NS(=O)(=O)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC2S1J	2-[(E)-3-(4-Pyrrolidin-1-ylphenyl)prop-2-enoyl]-3,4-dihydro-2H-naphthalen-1-one	Investigative	90645133	C23H23NO2	345.4	C1CCN(C1)C2=CC=C(C=C2)/C=C/C(=O)C3CCC4=CC=CC=C4C3=O	IC50 = 61230 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC3G8X	4-[5-(4-Chlorophenyl)tetrazol-1-yl]benzenesulfonamide	Investigative	57399158	C13H10ClN5O2S	335.77	C1=CC(=CC=C1C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N)Cl	IC50 = 62000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC4N0Y	2-(1-(1-(Difluoromethyl)-2-oxo-1,2-dihydropyridine-4-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid	Investigative	49765093	C19H16F2N2O5	390.3	CC1=C(C2=C(N1C(=O)C3=CC(=O)N(C=C3)C(F)F)C=CC(=C2)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC4ZL5	6-[(2-Acetoxyphenyl)thio]hexanoic acid	Investigative	9921835	C14H18O4S	282.36	CC(=O)OC1=CC=CC=C1SCCCCCC(=O)O	IC50 = 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC6UH3	1H-Pyrrole, 2-methyl-5-[4-(methylsulfonyl)phenyl]-	Investigative	10799759	C12H13NO2S	235.3	CC1=CC=C(N1)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC82MP	(R)-6-Chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52948912	C13H10ClF3O3	306.66	CC1=C(C=C2C=C([C@@H](OC2=C1C)C(F)(F)F)C(=O)O)Cl	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BC91TJ	(2E,5E)-2,5-Bis[[4-(dimethylamino)-2-nitrophenyl]methylidene]cyclopentan-1-one	Investigative	90645122	C23H24N4O5	436.5	CN(C1=CC(=C(C=C1)/C=C\\2/C(=O)/C(=C/C3=C(C=C(C=C3)N(C)C)[N+](=O)[O-])/CC2)[N+](=O)[O-])C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCDG20	1-(Carboxymethyl)-3,5-diphenyl-2-methylbenzene	Investigative	10040599	C21H18O2	302.4	CC1=C(C=C(C=C1C2=CC=CC=C2)C3=CC=CC=C3)CC(=O)O	IC50 = 120000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCJ3Q4	2-(5,6-Dihydro-9-hydroxy-2-methyl-2,6-methano-2H-1-benzoxocin-4-yl)-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one	Investigative	44559963	C33H30O9	570.6	CC(=CCC12C3=C(C=C(C=C3)O)OC1(C(=O)C4=C(O2)C=C(C(=C4O)C5=CC6(CC(C5)C7=C(O6)C=C(C=C7)O)C)O)O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCJ61T	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-[4-(trifluoromethoxy)phenyl]phenyl]propanoate	Investigative	56675533	C22H20F3NaO4	428.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC(F)(F)F)C(=O)[O-].[Na+]	IC50 = 72000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCO04V	N-[4-(2,3-Dimethylphenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728417	C23H20N2O4S	420.5	CC1=C(C(=CC=C1)C2=CC=C(C=C2)NC(=O)C3=C(C4=CC=CC=C4S(=O)(=O)N3)O)C	IC50 = 94700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCOB05	2-[6-Chloro-9-(hexylcarbamoyl)carbazol-2-yl]propanoic acid	Investigative	71458883	C22H25ClN2O3	400.9	CCCCCCNC(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCS4L6	Ciwujianoside C3	Investigative	21626481	C53H86O21	1059.2	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCS64T	2-Ethyl-1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10807315	C19H18FNO2S	343.4	CCC1=CC=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BCW57P	N-[(5-Bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide	Investigative	44460175	C16H13BrN2O2S	377.3	CC(=O)NC(C1=CC=CS1)C2=CC(=C3C=CC=NC3=C2O)Br	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD25RC	2-(4-Tert-Butylphenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	44271105	C26H24FNO2S2	465.6	CC(C)(C)C1=CC=C(C=C1)C2=NC(=C(S2)C3=CC=C(C=C3)S(=O)(=O)C)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD27MZ	1-(2-(4-(4-(Methylsulfonyl)-2-nitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805054	C19H22N2O6S	406.5	CS(=O)(=O)C1=CC(=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD2UY4	1-(2-(4-(4-Nitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49804919	C18H20N2O4	328.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD5Q3N	4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole	Investigative	15380222	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)C2=NNC(=C2C3=CC=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD8I2Z	2-Phenyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole	Investigative	22624559	C22H23NO3S	381.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(O2)C3=CC=CC=C3)C4CCCCC4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BD8PK7	4-Methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phenol	Investigative	775994	C17H16N2O	264.32	CC1=CC(=C(C=C1)O)C2=NNC(=C2)C3=CC=CC=C3C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BDC07X	N-[2-Cyano-4-(trifluoromethyl)phenyl]-2-(2-oxochromen-4-yl)oxypropanamide	Investigative	71460385	C20H13F3N2O4	402.3	CC(C(=O)NC1=C(C=C(C=C1)C(F)(F)F)C#N)OC2=CC(=O)OC3=CC=CC=C32	IC50 = 50250 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BDE9W0	3-Nitrooxypropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate	Investigative	57780777	C17H13ClN2O7	392.7	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)C(=O)OCCCO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BDJ0F2	4-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid	Investigative	10808453	C16H12N2O6S	360.3	C1=CC(=CC=C1C2=COC(=O)N2C3=CC=C(C=C3)C(=O)O)S(=O)(=O)N	IC50 = 59000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BDP45T	1-[2-(4-Phenoxyphenoxy)ethyl]pyrrolidine	Investigative	9993978	C18H21NO2	283.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BDU3J9	(2R)-2-[6-Chloro-9-(4-chlorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71449872	C22H15Cl2NO3	412.3	C[C@H](C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BE41BL	4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N,N-dimethyl-benzenesulfonamide	Investigative	10549657	C18H15F4N3O2S	413.4	CN(C)S(=O)(=O)C1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BE4T2Y	2-[6-Chloro-9-(4-chlorophenyl)sulfonylcarbazol-2-yl]propanoic acid	Investigative	16098411	C21H15Cl2NO4S	448.3	CC(C1=CC2=C(C=C1)C3=C(N2S(=O)(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BE50XS	1-(4-Methylsulfonylphenyl)-5-[4-(trifluoromethyl)phenyl]tetrazole	Investigative	57393945	C15H11F3N4O2S	368.3	CS(=O)(=O)C1=CC=C(C=C1)N2C(=NN=N2)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BE7GR5	2-(2,6-Dichloro-3-methyl-phenylamino)-N-isopropoxy-benzamide	Investigative	44365785	C18H20Cl2N2O2	367.3	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)NOC(C)(C)C)Cl	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BE7PD5	1-(2-(4-(2,4-Dinitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49804920	C18H19N3O6	373.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BEL35F	3-[2-(4-Methylsulfonylphenyl)phenyl]pyridine	Investigative	21223973	C18H15NO2S	309.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CN=CC=C3	IC50 = 87000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BEM15W	2-(1-(1-(Difluoromethyl)-6-oxo-1,2,5,6-tetrahydropyridine-3-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid	Investigative	52941574	C19H18F2N2O5	392.4	CC1=C(C2=C(N1C(=O)C3=CCC(=O)N(C3)C(F)F)C=CC(=C2)OC)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BEMZ75	4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid	Investigative	66548636	C19H21ClN2O3S	392.9	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BEV83K	(5Z)-2-[1-(6-Methoxynaphthalen-2-yl)ethyl]-5-(naphthalen-1-ylmethylidene)-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one	Investigative	118729079	C28H21N3O2S	463.6	CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C3=NN4C(=O)/C(=C/C5=CC=CC6=CC=CC=C65)/SC4=N3	IC50 = 68200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BEVP95	5-(4-(Methylsulfonyl)phenyl)-4-phenyl-3H-1,2-dithiole-3-thione	Investigative	11175990	C16H12O2S4	364.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=S)SS2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BF0B3H	N-[4-(3-Chlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728411	C21H15ClN2O4S	426.9	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)Cl)O	IC50 = 74700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BF41IZ	2-[4-[3-(Cyclopentylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	73054543	C21H22FNO4	371.4	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NC3CCCC3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BF4GR7	4-[3-Difluoromethyl-5-(2,5-dimethyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide	Investigative	10643308	C18H17F2N3O2S	377.4	CC1=CC(=C(C=C1)C)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BFN8I4	(5Z)-2-[1-(6-Methoxynaphthalen-2-yl)ethyl]-5-[(4-propan-2-ylphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one	Investigative	118729071	C27H25N3O2S	455.6	CC(C)C1=CC=C(C=C1)/C=C\\2/C(=O)N3C(=NC(=N3)C(C)C4=CC5=C(C=C4)C=C(C=C5)OC)S2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BFO4C7	Chembl4169332	Investigative	145955075	C15H15ClN8O3	390.78	C1COCC(=O)N1C2=CC=C(C=C2)NC3=NC(=NC(=N3)Cl)OCCN=[N+]=[N-]	IC50 = 75000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BFU91R	2,4,6-Trimethyl-3-(5-methyl-4-phenyl-isoxazol-3-yl)-benzenesulfonamide	Investigative	11302745	C19H20N2O3S	356.4	CC1=CC(=C(C(=C1C2=NOC(=C2C3=CC=CC=C3)C)C)S(=O)(=O)N)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BFV74L	p-Terphenyl	Investigative	7115	C18H14	230.3	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 = 144000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BFX1O9	4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiole-3-thione	Investigative	44564507	C16H11ClS3	334.9	CC1=CC=C(C=C1)C2=C(C(=S)SS2)C3=CC=C(C=C3)Cl	IC50 = 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BG0XT2	[(1S,2S,6R,10S,11R,13S,14R,15R)-14-Acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5,9-dioxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,7-dienyl] 2-methylbutanoate	Investigative	118727933	C27H36O9	504.6	CCC(C)C(=O)O[C@@]12[C@@H](C1(C)C)[C@@H]3C(=O)C(=C[C@]4([C@H]([C@]3([C@@H]([C@H]2OC(=O)C)C)O)C=C(C4=O)C)O)CO	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BG2A9V	3-[1-(3-Chloro-phenoxy)-2,2,2-trifluoro-ethyl]-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole	Investigative	10816219	C26H20ClF4NO3S	538	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(C(F)(F)F)OC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BG8CK2	4-[2-(3,4,5-Trifluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene	Investigative	10641720	C18H15F3O2S	352.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(CCC2)C3=CC(=C(C(=C3)F)F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BG8ZO2	2-(2-Chloro-6-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10645484	C18H14ClF3N2O2S	414.8	CC1=C(C(=CC=C1)Cl)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGCZ96	3-(4-Methylsulfonylphenyl)-4-phenylphenol	Investigative	15871996	C19H16O3S	324.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=CC(=C2)O)C3=CC=CC=C3	IC50 = 147000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGI7H3	6-Chloro-7-((2,5-dimethylpyrrolidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53323226	C18H19ClF3NO3	389.8	CC1CCC(N1CC2=C(C=C3C=C(C(OC3=C2)C(F)(F)F)C(=O)O)Cl)C	IC50 = 96000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGJ2B9	2-[4-[3-(Cyclohexylmethylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	73054545	C23H26FNO4	399.5	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NCC3CCCCC3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGJ53O	4-[5-(Difluoromethyl)-2-(4-sulfamoylphenyl)pyrazol-3-yl]benzamide	Investigative	10715523	C17H14F2N4O3S	392.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)C(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGMO76	N-[4-(3,4-Dichlorophenyl)phenyl]-4,6-dihydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728424	C21H14Cl2N2O5S	477.3	C1=CC(=CC=C1C2=CC(=C(C=C2)Cl)Cl)NC(=O)C3=C(C4=C(C=CC(=C4)O)S(=O)(=O)N3)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGP49B	1-(2-(4-(4-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805177	C19H20F3NO2	351.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGQ01J	2-[6-Chloro-9-(octylcarbamoyl)carbazol-2-yl]propanoic acid	Investigative	71449873	C24H29ClN2O3	428.9	CCCCCCCCNC(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGQ3F1	6-Chloro-7-(diisopropylamino)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	53320186	C17H19ClF3NO3	377.8	CC(C)N(C1=C(C=C2C=C(C(OC2=C1)C(F)(F)F)C(=O)O)Cl)C(C)C	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGR5K1	4-Amino-N-[5-(trifluoromethyl)pyridin-2-yl]benzamide	Investigative	24854031	C13H10F3N3O	281.23	C1=CC(=CC=C1C(=O)NC2=NC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BGY4M8	N-[3-(3,5-Dimethylanilino)pyridin-4-yl]methanesulfonamide	Investigative	76335832	C14H17N3O2S	291.37	CC1=CC(=CC(=C1)NC2=C(C=CN=C2)NS(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BH32JZ	(2R)-2-[4-[[(1R,2S)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid	Investigative	13148391	C15H20O3	248.32	C[C@H](C1=CC=C(C=C1)C[C@H]2CCC[C@@H]2O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BH53MB	4-[5-(4-Fluorophenyl)-4-propyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10717364	C19H17F4N3O2S	427.4	CCCC1=C(N(N=C1C(F)(F)F)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BH57JZ	3-(5-Chlorofuran-2-yl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole	Investigative	44194814	C14H7ClF3NO2	313.66	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BH71VQ	2-[6-Chloro-9-(cyclohexylcarbamoyl)carbazol-2-yl]propanoic acid	Investigative	71453518	C22H23ClN2O3	398.9	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)NC4CCCCC4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BH9C3M	2-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}ethanol	Investigative	16125427	C18H16ClFN2O4S	410.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCO)F)Cl	IC50 = 56000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHB71Y	[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-ylmethyl]-dimethyl-amine	Investigative	10738921	C21H23FN2O2S	386.5	CC1=C(C=C(N1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)CN(C)C	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHBD92	N-(3-Anilinopyridin-4-yl)-N-cyclopropylsulfonylcyclopropanesulfonamide	Investigative	76317623	C17H19N3O4S2	393.5	C1CC1S(=O)(=O)N(C2=C(C=NC=C2)NC3=CC=CC=C3)S(=O)(=O)C4CC4	IC50 = 56760 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHC31I	1,4-Benzodioxan-6-ylacetic acid	Investigative	87020	C10H10O4	194.18	C1COC2=C(O1)C=CC(=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHIO47	2,6-Di-tert-butyl-4-(5-propylsulfanyl-[1,3,4]thiadiazol-2-yl)-phenol	Investigative	135503854	C19H28N2OS2	364.6	CCCSC1=NN=C(S1)C2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHL71Y	2-(9-Benzyl-6-chlorocarbazol-2-yl)propanoic acid	Investigative	71458880	C22H18ClNO2	363.8	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC=CC=C4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHLF89	2-(6-Chloro-9H-carbazole-2-yl)propionic acid methyl ester	Investigative	14049818	C16H14ClNO2	287.74	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHQ0N6	3-(1,3-Benzodioxol-4-yl)-2-(4-methylphenyl)sulfonyl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706123	C18H15F3N2O4S	412.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=C4C(=CC=C3)OCO4	IC50 = 57360 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHS07O	Methyl 3-[(4-nitronaphthalen-1-yl)amino]benzoate	Investigative	70911877	C18H14N2O4	322.3	COC(=O)C1=CC(=CC=C1)NC2=CC=C(C3=CC=CC=C32)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHU2X5	(E)-2-[3-(2,4-Difluorophenyl)phenyl]-3-(4-methylsulfonylphenyl)prop-2-enoic acid	Investigative	76316303	C22H16F2O4S	414.4	CS(=O)(=O)C1=CC=C(C=C1)/C=C(\\C2=CC=CC(=C2)C3=C(C=C(C=C3)F)F)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHY3C0	(2R)-2-[6-Chloro-9-(1,3-oxazole-4-carbonyl)carbazol-2-yl]propanoic acid	Investigative	71457024	C19H13ClN2O4	368.8	C[C@H](C1=CC2=C(C=C1)C3=C(N2C(=O)C4=COC=N4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BHYC34	(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoic acid	Investigative	57394899	C21H20FN3O5	413.4	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)C3=CC=C(C=C3)F	IC50 = 200000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI3R0K	Acetic acid 2-(4-cyano-butylsulfanyl)-phenyl ester	Investigative	10848242	C13H15NO2S	249.33	CC(=O)OC1=CC=CC=C1SCCCCC#N	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI85SU	2-[3-Fluoro-4-[3-(propylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	90036150	C19H20FNO4	345.4	CCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI8E6T	4-[5-Tert-butyl-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68291773	C21H24N2O2	336.4	CC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI93DJ	2-Amino-N-[2-(trifluoromethyl)phenyl]benzamide	Investigative	5080393	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI98CZ	4-[3-(Difluoromethyl)-5-(4-methylsulfonylphenyl)pyrazol-1-yl]benzenesulfonamide	Investigative	11796738	C17H15F2N3O4S2	427.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BI9F1Z	4-[5-Tert-butyl-3-(4-ethoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548448	C22H26N2O3	366.5	CCOC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIEW03	2-[3-Fluoro-4-[3-(2-phenylethylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	73054548	C24H22FNO4	407.4	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NCCC3=CC=CC=C3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIF8Y2	N-(3-Cyclopentylamino-4-pyridinyl)methanesulfonamide	Investigative	44473651	C11H17N3O2S	255.34	CS(=O)(=O)NC1=C(C=NC=C1)NC2CCCC2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIH3Y1	Chembl4290080	Investigative	145989313	C19H21NO3SSi	371.5	C[Si](C)(C)C1=C(ON=C1C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIM75L	Meclofenamic acid derivative, 27	Investigative	10409583	C22H20Cl2N2O2	415.3	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)NCCOC3=CC=CC=C3)Cl	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BINJ79	2-[6-Chloro-9-[(4-cyanophenyl)methyl]carbazol-2-yl]propanoic acid	Investigative	71457025	C23H17ClN2O2	388.8	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC=C(C=C4)C#N)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIPY25	N-(3-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	Investigative	24853950	C13H10F3N3O	281.23	C1=CC(=C(N=C1)NC(=O)C2=CC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIRD47	N-[4-(3,4-Dimethylphenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728429	C23H20N2O4S	420.5	CC1=C(C=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=C(C4=CC=CC=C4S(=O)(=O)N3)O)C	IC50 ~ 57700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIV25M	2-Fluoro-1-methoxy-4-[2-(4-methylsulfonylphenyl)phenyl]benzene	Investigative	10546170	C20H17FO3S	356.4	COC1=C(C=C(C=C1)C2=CC=CC=C2C3=CC=C(C=C3)S(=O)(=O)C)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIV78W	2,4,6-Trimethyl-3-[5-methyl-4-(4-sulfamoyl-phenyl)-isoxazol-3-yl]-benzenesulfonamide	Investigative	11487377	C19H21N3O5S2	435.5	CC1=CC(=C(C(=C1C2=NOC(=C2C3=CC=C(C=C3)S(=O)(=O)N)C)C)S(=O)(=O)N)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIWU85	5-[(5-Anilino-1,3,4-thiadiazol-2-yl)methyl]-7-[(4-methoxyphenyl)methyl]-3-methyl-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70687599	C23H20N6O3S	460.5	CC1=NOC2=C1C(=O)N(N=C2CC3=CC=C(C=C3)OC)CC4=NN=C(S4)NC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BIX5H6	1,5-Diphenyl-3-trifluoromethyl-1H-pyrazole	Investigative	10424186	C16H11F3N2	288.27	C1=CC=C(C=C1)C2=CC(=NN2C3=CC=CC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ0G8A	2-[3-Fluoro-4-[3-(2-methylpropylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	73054544	C20H22FNO4	359.4	CC(C)CNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ0OZ2	5-[[5-(Ethylamino)-1,3,4-thiadiazol-2-yl]methyl]-7-[(4-methoxyphenyl)methyl]-3-methyl-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70693860	C19H20N6O3S	412.5	CCNC1=NN=C(S1)CN2C(=O)C3=C(C(=N2)CC4=CC=C(C=C4)OC)ON=C3C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ0Y1Z	2-(Phenylacetyloxy)Ethanesulfonylhydroxamic Acid	Investigative	51351150	C10H13NO5S	259.279	C1=CC=C(C=C1)CC(=O)OCCS(=O)(=O)NO	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ24DB	2-(4-Chlorophenyl)-3-(4-methylsulfonylanilino)-1,3-thiazolidin-4-one	Investigative	70689056	C16H15ClN2O3S2	382.9	CS(=O)(=O)C1=CC=C(C=C1)NN2C(SCC2=O)C3=CC=C(C=C3)Cl	IC50 = 121700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ27AZ	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-2-phenylphenyl]propanoate	Investigative	56665216	C21H21NaO3	344.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=CC=C3)C(=O)[O-].[Na+]	IC50 = 70000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ3VO6	4-(4-Methanesulfonyl-phenyl)-3-phenyl-5H-[1,2]oxathiole 2-oxide	Investigative	11450459	C16H14O4S2	334.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(S(=O)OC2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ4D1F	3-Methyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]isoxazole	Investigative	10947517	C17H14FNO3S	331.4	CC1=NOC(=C1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ4FV3	Hederasaponin B	Investigative	21626480	C59H96O25	1205.4	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ95GE	4-[5-Tert-butyl-3-(3-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548634	C20H21FN2O2	340.4	CC(C)(C)C1=NN(C(C1)C2=CC(=CC=C2)F)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJ9FO6	Chembl4160157	Investigative	145960574	C22H23ClN6O5S	519	CC1=CC=C(C=C1)S(=O)(=O)NCCOC2=NC(=NC(=N2)NC3=CC=C(C=C3)N4CCOCC4=O)Cl	IC50 = 80000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJAG15	N-(4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide	Investigative	49805306	C19H24N2O4S	376.5	CS(=O)(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJBH34	2-Pyridinecarboxylic acid, 6-((5-chloro-2-((4-chloro-2-fluorophenyl)methoxy)phenyl)methyl)-, sodium salt	Investigative	23696973	C20H13Cl2FNNaO3	428.2	C1=CC(=NC(=C1)C(=O)[O-])CC2=C(C=CC(=C2)Cl)OCC3=C(C=C(C=C3)Cl)F.[Na+]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJM3H2	7-Benzyl-3-methyl-5-[(4-phenyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70681274	C22H18N6O2S	430.5	CC1=NOC2=C1C(=O)N(N=C2CC3=CC=CC=C3)CC4=NNC(=S)N4C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BJON65	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-phenylmethanone;hydrochloride	Investigative	46906731	C33H36ClFN2O4	579.1	COC1(CCOCC1)C2=CC(=CC(=C2)F)OCCCN3CCC4=C(C3)C5=CC=CC=C5N4C(=O)C6=CC=CC=C6.Cl	IC50 = 101900 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK0ZF6	5-Methyl-3-(oxolan-2-yl)-4-phenyl-1,2-oxazole	Investigative	44194816	C14H15NO2	229.27	CC1=C(C(=NO1)C2CCCO2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK1Y5E	2-(5-Fluoro-2-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole	Investigative	10810863	C18H14F4N2O2S	398.4	CC1=C(C=C(C=C1)F)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK4I2Z	2-(6-Chloro-9-hexylsulfonylcarbazol-2-yl)propanoic acid	Investigative	71460692	C21H24ClNO4S	421.9	CCCCCCS(=O)(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK5JL2	(3E,5E)-1-Benzyl-3,5-bis[(4-pyrrolidin-1-ylphenyl)methylidene]piperidin-4-one	Investigative	118706209	C34H37N3O	503.7	C1CN(CC1)C2=CC=C(C=C2)/C=C\\3/C(=O)/C(=C/C4=CC=C(C=C4)N5CCCC5)/CN(C3)CC6=CC=CC=C6	IC50 = 57220 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK5O4P	4-[4-Chloro-5-[3-fluoro-4-(3-hydroxypropoxy)phenyl]imidazol-1-yl]benzenesulfonamide	Investigative	16125422	C18H17ClFN3O4S	425.9	C1=CC(=CC=C1N2C=NC(=C2C3=CC(=C(C=C3)OCCCO)F)Cl)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK70EO	Methyl 3,5-diphenyl-4-isoxazolecarboxylate	Investigative	827480	C17H13NO3	279.29	COC(=O)C1=C(ON=C1C2=CC=CC=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BK7D2P	(2E)-2-[(4-Pyrrolidin-1-ylphenyl)methylidene]-3H-inden-1-one	Investigative	38864639	C20H19NO	289.4	C1CCN(C1)C2=CC=C(C=C2)/C=C/3\\CC4=CC=CC=C4C3=O	IC50 = 54640 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BKD8E4	4-[2-(5-Methoxypyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10524898	C16H13F3N4O3S	398.4	COC1=CN=CC(=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BKGP69	2,2,2-Trifluoro-1-[4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]ethanone	Investigative	10621114	C18H9F7N2O	402.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)C(=O)C(F)(F)F)C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BKGY62	3-[4-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid	Investigative	122192742	C13H10F5NO2S	339.28	C1=CC(=CC(=C1)NC2=CC=C(C=C2)S(F)(F)(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BKL09N	2-(9H-Carbazol-2-yl)propanoic acid	Investigative	13771052	C15H13NO2	239.27	CC(C1=CC2=C(C=C1)C3=CC=CC=C3N2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BKL7W1	Disodium;4-[2-(1-carboxylatoethyl)-5-[(2-oxocyclopentyl)methyl]phenyl]benzoate	Investigative	56672145	C22H20Na2O5	410.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)C(=O)[O-])C(=O)[O-].[Na+].[Na+]	IC50 = 76000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BL1I0Q	4-Hydroxy-1,1-dioxo-N-(4-phenylphenyl)-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728413	C21H16N2O4S	392.4	C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=C(C4=CC=CC=C4S(=O)(=O)N3)O	IC50 = 92600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BL2KA0	N-[3-(3-Methoxyphenylamino)-4-pyridinyl]methanesulfonamide	Investigative	44473494	C13H15N3O3S	293.34	COC1=CC=CC(=C1)NC2=C(C=CN=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BL4GQ6	3-(4-Methylsulfonylphenyl)-4-phenylaniline	Investigative	44384324	C19H17NO2S	323.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=CC(=C2)N)C3=CC=CC=C3	IC50 = 194000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BL6J8Z	2-(4-Mesylphenyl)-3-(4-fluorophenyl)-5-nitro-1H-pyrrole	Investigative	10316456	C17H13FN2O4S	360.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)[N+](=O)[O-])C3=CC=C(C=C3)F	IC50 = 63000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BL6WH2	N-(4-Bromophenyl)-1-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-carboxamide	Investigative	90654427	C25H23BrN4O5	539.4	COC1=CC=C(C=C1)N2C(=NC(=N2)C(=O)NC3=CC=C(C=C3)Br)C4=CC(=C(C(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BLB75T	Acetic acid 2-phenethylsulfanyl-phenyl ester	Investigative	9900153	C16H16O2S	272.4	CC(=O)OC1=CC=CC=C1SCCC2=CC=CC=C2	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BLH03C	4-[5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548637	C23H19FN2O3	390.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BLYX03	N-(3-Phenylsulfonyl-4-pyridinyl)methanesulfonamide	Investigative	11415723	C12H12N2O4S2	312.4	CS(=O)(=O)NC1=C(C=NC=C1)S(=O)(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM0QB7	N-[3-(3-Ethylphenylamino)-4-pyridinyl]methanesulfonamide	Investigative	44475683	C14H17N3O2S	291.37	CCC1=CC(=CC=C1)NC2=C(C=CN=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM0U2Z	Sanggenon D	Investigative	9987332	C40H36O12	708.7	CC1=C[C@@H]([C@H]([C@@H](C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C5=C(C=C4O)OC6(C7=C(C=C(C=C7)O)OC6(C5=O)CC=C(C)C)O)O	IC50 = 73000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM4O2L	2-[6-Chloro-9-(4-methoxybenzoyl)carbazol-2-yl]propanoic acid	Investigative	71451683	C23H18ClNO4	407.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=C(C=C4)OC)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM56JK	[2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid sodium salt	Investigative	50901657	C29H31N2NaO5	510.6	CCN(CC1=C(C=CC(=C1)C2=CN=C(C=C2)OCC)C3=C(C=CC(=C3)CC(=O)[O-])OC)C(=O)C4CC4.[Na+]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM71EY	4-(4-Fluorophenyl)-5-(4-methylsulfonylphenyl)dithiole-3-thione	Investigative	11474526	C16H11FO2S4	382.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=S)SS2)C3=CC=C(C=C3)F	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM72KB	5-(4-Fluorophenyl)-1-(4-nitrophenyl)-3-(trifluoromethyl)pyrazole	Investigative	11792223	C16H9F4N3O2	351.25	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)[N+](=O)[O-])C(F)(F)F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM8J3Y	3-Oxaheneicosa-5,9,12,15,18-pentaenoic acid	Investigative	44584287	C20H30O3	318.4	CC/C=C/C/C=C/C/C=C/C/C=C/CC/C=C/COCC(=O)O	IC50 = 180000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BM9ZJ0	3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5-thiocyanato-1H-pyrrole	Investigative	10474426	C18H13FN2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)SC#N)C3=CC=C(C=C3)F	IC50 = 72000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BMC5S8	2-(4-Methylphenyl)sulfonyl-3-naphthalen-2-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706119	C21H17F3N2O2S	418.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=CC4=CC=CC=C4C=C3	IC50 = 95380 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BMO3U7	4-[5-(4-Methylphenyl)tetrazol-1-yl]benzenesulfonamide	Investigative	57393943	C14H13N5O2S	315.35	CC1=CC=C(C=C1)C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BMZX93	4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	5181298	C23H20N2O3	372.4	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN08DI	1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazole-4-carboxylic acid ethyl ester	Investigative	10499452	C18H17N3O4S	371.4	CCOC(=O)C1=CN(C(=N1)C2=CN=CC=C2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN1V8Y	2-(6-Chloro-9H-carbazol-2-yl)-N-phenylpropanamide	Investigative	71451686	C21H17ClN2O	348.8	CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN1XG8	1-Isopropyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10660176	C15H19NO2S	277.4	CC1=CC=C(N1C(C)C)C2=CC=C(C=C2)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN69AX	2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carboxylic Acid	Investigative	11793960	C17H13ClN2O4S	376.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN6S8B	N-(4-Aminophenyl)-4-(trifluoromethyl)benzamide	Investigative	24689970	C14H11F3N2O	280.24	C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN7I6K	N-(2-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16774693	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN7S1I	Pallidol	Investigative	484757	C28H22O6	454.5	C1=CC(=CC=C1[C@H]2[C@H]3[C@H]([C@@H](C4=C3C=C(C=C4O)O)C5=CC=C(C=C5)O)C6=C2C(=CC(=C6)O)O)O	IC50 = 80000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BN8FW2	[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]methanamine	Investigative	10594776	C17H16ClN3O2S	361.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=C(C=C3)Cl)CN	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BNB68G	Chembl4170326	Investigative	145954463	C20H24O5	344.4	CC(C)CC(=O)OC/C(=C/CC1=C(C=CC2=C1OC(=O)C=C2)OC)/C	IC50 = 56400 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BNC4I7	5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiole-3-thione	Investigative	44564506	C16H11ClS3	334.9	CC1=CC=C(C=C1)C2=C(SSC2=S)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BND25B	3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805174	C17H19N3O4	329.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=C(C=CC=N3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BNJX08	4-[5-(4-Fluoro-phenyl)-pyrazol-1-yl]-benzenesulfonamide	Investigative	10852952	C15H12FN3O2S	317.3	C1=CC(=CC=C1C2=CC=NN2C3=CC=C(C=C3)S(=O)(=O)N)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BNO9C4	(8-Methoxy-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)-phenylmethanone;hydrochloride	Investigative	46906687	C19H19ClN2O2	342.8	COC1=CC2=C(C=C1)N(C3=C2CNCC3)C(=O)C4=CC=CC=C4.Cl	IC50 = 87600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BNX5L6	4-[5-(4-Ethylsulfanyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-2-hydroxymethyl-benzenesulfonamide	Investigative	44364510	C19H18F3N3O3S2	457.5	CCSC1=CC=C(C=C1)C2=CC(=NN2C3=CC(=C(C=C3)S(=O)(=O)N)CO)C(F)(F)F	IC50 = 51200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BO1GS0	5-Methanesulfonyl-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid methyl ester	Investigative	11025137	C19H19NO5S	373.4	COC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)C)C=C2C(=O)OC	IC50 = 51300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BO6Z7H	2-(2-Oxochromen-4-yl)oxy-N-pyridin-4-ylpropanamide	Investigative	71451368	C17H14N2O4	310.3	CC(C(=O)NC1=CC=NC=C1)OC2=CC(=O)OC3=CC=CC=C32	IC50 = 52390 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BO76YP	3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-4-phenyl-isoxazole	Investigative	11382825	C19H18ClNO4	359.8	CC1=C(C(=NO1)C2=C(C(=C(C=C2OC)OC)Cl)OC)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BO8V3Z	(Z)-4-Amino-4-(furan-2-yl)-3-phenylbut-3-en-2-one	Investigative	71682136	C14H13NO2	227.26	CC(=O)/C(=C(/C1=CC=CO1)\\N)/C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOAN10	2-[6-Chloro-9-(2-chlorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71451684	C22H15Cl2NO3	412.3	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=CC=C4Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOEP86	3-(3,4-Dimethoxyphenyl)-1,2-dihydronaphthalene	Investigative	11608668	C18H18O2	266.3	COC1=C(C=C(C=C1)C2=CC3=CC=CC=C3CC2)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOH89M	Clematichinenoside B	Investigative	49799272	C70H114O35	1515.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOK1Y4	2-[4-[3-(Butylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	73054805	C20H22FNO4	359.4	CCCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOL0Z6	2-[6-Chloro-9-(1H-imidazole-5-carbonyl)carbazol-2-yl]propanoic acid	Investigative	71457023	C19H14ClN3O3	367.8	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CN=CN4)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOQL75	Acetic acid 2-(5-acetoxy-pentylsulfanyl)-phenyl ester	Investigative	9857378	C15H20O4S	296.4	CC(=O)OCCCCCSC1=CC=CC=C1OC(=O)C	IC50 = 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BORW68	N-(3',4'-Dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide	Investigative	54728414	C21H14Cl2N2O4S	461.3	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOS73C	Z-Val-Gly-OH	Investigative	7005167	C15H20N2O5	308.33	CC(C)[C@@H](C(=O)NCC(=O)O)NC(=O)OCC1=CC=CC=C1	IC50 = 55000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BOVD92	Benzenesulfonamide,4-(3-methyl-5-phenyl-1h-pyrazol-1-yl)-	Investigative	10710312	C16H15N3O2S	313.4	CC1=NN(C(=C1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 62800 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BP34KB	(4-Bromophenyl)-[2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]methanone;hydrochloride	Investigative	46906739	C34H37BrClFN2O5	688	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)Br.Cl	IC50 = 85400 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BP4LE1	4-[5-[4-(Trifluoromethyl)phenyl]tetrazol-1-yl]benzenesulfonamide	Investigative	57397474	C14H10F3N5O2S	369.32	C1=CC(=CC=C1C2=NN=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BP59JX	(2S)-2-[[(2R)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-3-hydroxypropanoic acid	Investigative	57384031	C24H25FN4O6S	516.5	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)O)NC(=O)C3=CC=C(C=C3)F	IC50 = 85000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BP6V7T	2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]ethyl N-(3-nitrooxypropylsulfamoyl)carbamate	Investigative	11854079	C23H25ClN4O9S	569	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CCOC(=O)NS(=O)(=O)NCCCO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BP81OK	2-[9-(Butylcarbamoyl)-6-chlorocarbazol-2-yl]propanoic acid	Investigative	71460693	C20H21ClN2O3	372.8	CCCCNC(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPC7B6	2-(9-Acetyl-6-chlorocarbazol-2-yl)propanoic acid	Investigative	71449874	C17H14ClNO3	315.7	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPI5B4	2-{[(3'',4''-Dichloro-biphenyl-4-ylcarbamoyl)-methyl]-sulfamoyl}-benzoic acid	Investigative	46880353	C21H16Cl2N2O5S	479.3	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)NCC(=O)NC2=CC=C(C=C2)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPK47W	N-[3-(2-Methoxyphenylamino)-4-pyridinyl]methanesulfonamide	Investigative	44475684	C13H15N3O3S	293.34	COC1=CC=CC=C1NC2=C(C=CN=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPK9C4	3-(5-Chlorofuran-2-yl)-4-phenyl-5-hydroxymethylisoxazole	Investigative	57780767	C14H10ClNO3	275.68	C1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(O3)Cl)CO	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPO09B	(3E,5E)-1-Methyl-3,5-bis[(4-pyrrolidin-1-ylphenyl)methylidene]piperidin-4-one	Investigative	118706208	C28H33N3O	427.6	CN1C/C(=C\\C2=CC=C(C=C2)N3CCCC3)/C(=O)/C(=C/C4=CC=C(C=C4)N5CCCC5)/C1	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPO7C9	1-(2-(4-(4-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805053	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPTS73	4-[3-(3-Nitrophenyl)-5-propan-2-yl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	129012346	C19H19N3O4	353.4	CC(C)C1=NN(C(C1)C2=CC(=CC=C2)[N+](=O)[O-])C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPU19E	Kazinol B	Investigative	480869	C25H28O4	392.5	CC(=CCC1=C(C=C2C=CC(OC2=C1O)(C)C)[C@@H]3CCC4=C(O3)C=C(C=C4)O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPX7S1	2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]ethyl N-(3-nitrooxypropyl)carbamate	Investigative	11854078	C23H24ClN3O7	489.9	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CCOC(=O)NCCCO[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BPZ0Y6	1-(2-(4-(4-Fluorophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	18678268	C18H20FNO2	301.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQ2B5D	(2S)-2-[4-[[(1S,2R)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid	Investigative	13148392	C15H20O3	248.32	C[C@@H](C1=CC=C(C=C1)C[C@@H]2CCC[C@H]2O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQ4Z3E	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)-1-methyl-4,5-dibromo-1H-pyrrole	Investigative	9982906	C18H14Br2FNO2S	487.2	CN1C(=C(C(=C1Br)Br)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 55670 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQ61WT	1-(2-(4-(4-Bromophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805179	C18H20BrNO2	362.3	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQ7D8R	Bromoloxoprofen	Investigative	49837500	C15H16BrNaO3	347.18	CC(C1=C(C=C(C=C1)CC2CCCC2=O)Br)C(=O)[O-].[Na+]	IC50 = 65000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQ7T1O	Cussonoside B	Investigative	169187	C48H78O17	927.1	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQB0D7	3-(4-Tert-butylanilino)benzoic acid	Investigative	53316889	C17H19NO2	269.34	CC(C)(C)C1=CC=C(C=C1)NC2=CC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQE8C2	2,3-Dichloro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1H-pyrrole	Investigative	11740714	C17H12Cl2FNO2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=C(N2)Cl)Cl)C3=CC=C(C=C3)F	IC50 = 69000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQFK50	2-[6-Chloro-9-[hexyl(methyl)carbamoyl]carbazol-2-yl]propanoic acid	Investigative	71460694	C23H27ClN2O3	414.9	CCCCCCN(C)C(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQS7L0	1-(4-Methanesulfonyl-phenyl)-2-phenyl-1H-imidazole	Investigative	10804032	C16H14N2O2S	298.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=CN=C2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BQU6F9	(4-Fluoro-2-(4-(methylsulfonyl)phenyl)but-1-ene-1,1-diyl)dibenzene	Investigative	49864438	C23H21FO2S	380.5	CS(=O)(=O)C1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=CC=C3)CCF	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR0CT9	N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]trifluoromethanesulfonamide	Investigative	11463338	C12H7Cl2F3N2O3S	387.2	C1=CN=CC(=C1NS(=O)(=O)C(F)(F)F)OC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR13WD	N-[4-[5-(4-Fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]methanesulfonamide	Investigative	10524951	C17H13F4N3O2S	399.4	CS(=O)(=O)NC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR14AI	4-[2-(4-Methylpyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10714907	C16H13F3N4O2S	382.4	CC1=C(C=NC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 51000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR2GD9	4-[5-Pyridin-4-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10666704	C15H11F3N4O2S	368.3	C1=CC(=CC=C1N2C(=CC(=N2)C(F)(F)F)C3=CC=NC=C3)S(=O)(=O)N	IC50 = 64700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR2K7S	12-O-[3-Methyl-2-butenoyl]-4-deoxyphorbol 13-acetate	Investigative	44583798	C29H41NO7	515.6	C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@@H]4CC(=C3)CO)C)O)OC(=O)C)OC(=O)C(=C(C)C)N(C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR3KO2	Norartocarpetin	Investigative	5481970	C15H10O6	286.24	C1=CC(=C(C=C1O)O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR53MX	2-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-5-methyl-1H-pyrrole	Investigative	10830212	C18H16FNO2S	329.4	CC1=CC=C(N1C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR6E4B	Epicatechin-(4beta-8)-epiafzelechin	Investigative	14015948	C30H26O11	562.5	C1[C@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC=C(C=C6)O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BR8UP2	2-[4-[3-(Ethylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	90036448	C18H18FNO4	331.3	CCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRA05V	2-[6-Chloro-9-(3,4-dichlorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71460691	C22H14Cl3NO3	446.7	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC(=C(C=C4)Cl)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRAF14	Loxoprofen	Investigative	3965	C15H18O3	246.3	CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRC17J	N-[4-(2,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728416	C21H14Cl2N2O4S	461.3	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=C(C=C(C=C4)Cl)Cl)O	IC50 ~ 74800 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRG31Y	2-(4-Methylsulfinylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	10574542	C18H15F3N2O3S2	428.5	CS(=O)C1=CC=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRH36X	4-[5-(3,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68292453	C25H24N2O5	432.5	COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)C(=O)O)C4=CC(=C(C=C4)OC)OC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRI78N	4-[5-Tert-butyl-3-(3,4-dichlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548446	C20H20Cl2N2O2	391.3	CC(C)(C)C1=NN(C(C1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRI89U	2-Amino-N-[3-(trifluoromethyl)phenyl]benzamide	Investigative	1517275	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRJI73	2-(2-Chlorophenyl)-4-(2,5-difluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole	Investigative	44271141	C22H14ClF2NO2S2	461.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(N=C(S2)C3=CC=CC=C3Cl)C4=C(C=CC(=C4)F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BRJP30	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine	Investigative	49805049	C17H20N2O2	284.35	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS1WG4	5-Acetoxymethyl-3-(5-chlorofuran-2-yl)-4-phenylisoxazole	Investigative	57780766	C16H12ClNO4	317.72	CC(=O)OCC1=C(C(=NO1)C2=CC=C(O2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS38CE	2-[6-Chloro-9-(4-chlorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71460695	C22H15Cl2NO3	412.3	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 = 72300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS3C5Y	2-(4-Chlorophenyl)-N,N-diethyl-1-(4-methylsulfonylphenyl)imidazole-4-carboxamide	Investigative	10526696	C21H22ClN3O3S	431.9	CCN(CC)C(=O)C1=CN(C(=N1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS62OW	5-(4-Fluoro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid amide	Investigative	12080914	C16H13FN4O3S	360.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)N)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS74ZD	1-Butyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole	Investigative	10541610	C16H21NO2S	291.4	CCCCN1C(=CC=C1C2=CC=C(C=C2)S(=O)(=O)C)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS95HZ	Kizuta Saponin K12	Investigative	49799268	C59H96O26	1221.4	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BS9AN7	4-[5-Tert-butyl-3-(4-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	66548270	C20H22N2O3	338.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)O)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSG98J	1-(2-(4-(3-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805052	C19H23NO4S	361.5	CS(=O)(=O)C1=CC=CC(=C1)OC2=CC=C(C=C2)OCCN3CCCC3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSJ3U6	[(1R,2R,6R,10S,11R,13S,14R,15R)-1,14-Dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylbutanoate	Investigative	118727932	C25H36O6	432.5	CCC(C)C(=O)O[C@@]12[C@@H](C1(C)C)[C@@H]3C=C(C[C@@H]4[C@H]([C@]3([C@@H]([C@H]2O)C)O)C=C(C4=O)C)CO	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSJ98I	(R)-8-Methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	52942694	C13H8F6O4	342.19	CC1=CC(=CC2=C1O[C@H](C(=C2)C(=O)O)C(F)(F)F)OC(F)(F)F	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSN3U4	Huzhangoside D	Investigative	49799270	C64H104O30	1353.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSU3M4	[(1S,2S,6R,10S,11R,13S,14R,15R)-1,6-Dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-14-[(E)-2-methylbut-2-enoyl]oxy-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylbutanoate	Investigative	20675009	C30H42O8	530.6	CCC(C)C(=O)O[C@@]12[C@@H](C1(C)C)[C@@H]3C=C(C[C@]4([C@H]([C@]3([C@@H]([C@H]2OC(=O)/C(=C/C)/C)C)O)C=C(C4=O)C)O)CO	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSUD29	Chembl4177170	Investigative	145971990	C15H17ClN6O3	364.79	C1COCC(=O)N1C2=CC=C(C=C2)NC3=NC(=NC(=N3)Cl)OCCN	IC50 = 90000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BSZO92	5-(1,2-Dihydro-3-naphthalenyl)-1,3-benzodioxole	Investigative	44424403	C17H14O2	250.29	C1CC(=CC2=CC=CC=C21)C3=CC4=C(C=C3)OCO4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BT1PH7	1-(2-(4-(3-Nitrophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49804918	C18H20N2O4	328.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BT2I6O	(2E)-2-[[4-(Diethoxymethyl)phenyl]methylidene]-3,4-dihydronaphthalen-1-one	Investigative	90645114	C22H24O3	336.4	CCOC(C1=CC=C(C=C1)/C=C/2\\CCC3=CC=CC=C3C2=O)OCC	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BT5J8V	(4-Chlorophenyl)-[2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]methanone;hydrochloride	Investigative	46845032	C34H37Cl2FN2O5	643.6	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)Cl.Cl	IC50 = 197900 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BTDC57	4-(4-(Methylsulfonyl)phenyl)-5-p-tolyl-3H-1,2-dithiole-3-thione	Investigative	44564000	C17H14O2S4	378.6	CC1=CC=C(C=C1)C2=C(C(=S)SS2)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BTF70K	N-(3-Aminophenyl)-3-(trifluoromethyl)benzamide	Investigative	20117519	C14H11F3N2O	280.24	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=CC=CC(=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BTJ51W	Acetic acid 2-(3-propoxy-propylsulfanyl)-phenyl ester	Investigative	10778330	C14H20O3S	268.37	CCCOCCCSC1=CC=CC=C1OC(=O)C	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BTKQ54	N-[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728405	C23H18Cl2N2O4S	489.4	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)CCC4=CC(=C(C=C4)Cl)Cl)O	IC50 ~ 68000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BTM8U5	N-(5-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide	Investigative	24853949	C13H10F3N3O	281.23	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=NC=C(C=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU02PO	Chembl4279197	Investigative	145978940	C19H20FNO3SSi	389.5	C[Si](C)(C)C1=C(ON=C1C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU15YB	1-(4-Methylsulfonylphenyl)-2-thiophen-3-yl-4-(trifluoromethyl)imidazole	Investigative	10619274	C15H11F3N2O2S2	372.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CSC=C3)C(F)(F)F	IC50 = 51000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU3P6F	2-[6-Chloro-9-[(4-methoxyphenyl)methyl]carbazol-2-yl]propanoic acid	Investigative	71458881	C23H20ClNO3	393.9	CC(C1=CC2=C(C=C1)C3=C(N2CC4=CC=C(C=C4)OC)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU4V3N	2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-1,2-benzothiazol-3-one	Investigative	134154737	C20H20ClN3O2S	401.9	C1CN(CCN1C2=CC(=CC=C2)Cl)C(=O)CCN3C(=O)C4=CC=CC=C4S3	IC50 = 128824.96 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU51GK	(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoic acid	Investigative	57401899	C30H29FN4O7	576.6	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)C4=CC=C(C=C4)F	IC50 = 180000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU7V6A	Chembl4175569	Investigative	145972167	C17H19ClN6O3	390.8	C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)N4CCOCC4=O)Cl	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU91HB	4-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine	Investigative	10570970	C16H12F3N3O2S	367.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=NC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU9K3G	2-[3-Fluoro-4-[3-(propan-2-ylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	90036900	C19H20FNO4	345.4	CC(C)NC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BU9Y8E	1-(2-(4-(4-Chlorophenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805178	C18H20ClNO2	317.8	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BUC5N8	4-(1-Morpholin-4-yl-1-oxopropan-2-yl)oxychromen-2-one	Investigative	71454915	C16H17NO5	303.31	CC(C(=O)N1CCOCC1)OC2=CC(=O)OC3=CC=CC=C32	IC50 = 69940 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BUC86H	US9271961, Bmt 3-224	Investigative	124222778	C16H13NO5	299.28	CC(=O)C1=CC(=C(C=C1)C(=O)O)NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BUCX40	3-(4-Acetylanilino)benzoic acid	Investigative	11184397	C15H13NO3	255.27	CC(=O)C1=CC=C(C=C1)NC2=CC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BUD95L	2-(2,6-Dichloro-3-methYlphenyl)amino-N-methoxybenzamide	Investigative	19815165	C15H14Cl2N2O2	325.2	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)NOC)Cl	IC50 = 55000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BV0N7C	[1-[4-[5-Chloro-3-(4-methylsulfonylphenyl)imidazol-4-yl]-2-fluorophenoxy]-3-nitrooxypropan-2-yl] nitrate	Investigative	16125491	C19H16ClFN4O9S	530.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCC(CO[N+](=O)[O-])O[N+](=O)[O-])F)Cl	IC50 = 76000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BV3H1X	1-(2-(4-(3-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine	Investigative	49805176	C19H20F3NO2	351.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC(=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BV9G7Y	2-[4-[3-(Cyclopropylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	90036800	C19H18FNO4	343.3	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NC3CC3)F)C(=O)O	IC50 = 74300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVA4F8	3-[(4-Bromophenyl)Amino]Benzoic Acid	Investigative	53316888	C13H10BrNO2	292.13	C1=CC(=CC(=C1)NC2=CC=C(C=C2)Br)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVB6W2	(3E,5E)-1-Benzyl-3,5-bis[[4-(diethoxymethyl)phenyl]methylidene]piperidin-4-one	Investigative	90645110	C36H43NO5	569.7	CCOC(OCC)C1=CC=C(C=C1)/C=C\\2/C(=O)/C(=C/C3=CC=C(C=C3)C(OCC)OCC)/CN(C2)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVB93O	Acetic acid 2-(5-hydroxy-pentylsulfanyl)-phenyl ester	Investigative	10729633	C13H18O3S	254.35	CC(=O)OC1=CC=CC=C1SCCCCCO	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVDT20	Acetic acid 2-propylsulfanyl-phenyl ester	Investigative	9813147	C11H14O2S	210.29	CCCSC1=CC=CC=C1OC(=O)C	IC50 = 66000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVF8E1	N-(4-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide	Investigative	24853948	C13H10F3N3O	281.23	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=NC=CC(=C2)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVHZ43	1,3-Dichloro-5-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-2-methoxybenzene	Investigative	10789363	C20H14Cl2F2O3S	443.3	COC1=C(C=C(C=C1Cl)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVL5C1	N-[3-(4-Chlorobenzoyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728410	C22H15ClN2O5S	454.9	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=CC(=C3)C(=O)C4=CC=C(C=C4)Cl)O	IC50 = 95300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BVUM70	4-[3-(4-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid	Investigative	68293323	C20H21BrN2O2	401.3	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)Br)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BW0SJ1	1-(4-Benzenesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10762141	C22H16FNO2S	377.4	C1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)N3C=CC=C3C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BW1K2S	4-(4-(Methylsulfonyl)phenyl)-5-phenyl-3H-1,2-dithiole-3-thione	Investigative	44563999	C16H12O2S4	364.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SSC2=S)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BW28IU	3-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid	Investigative	10666215	C16H12N2O6S	360.3	C1=CC(=CC(=C1)N2C(=COC2=O)C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BW5V2F	4-[(4-Oxo-2-phenyl-1,3-thiazolidin-3-yl)amino]benzenesulfonamide	Investigative	70695366	C15H15N3O3S2	349.4	C1C(=O)N(C(S1)C2=CC=CC=C2)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 78200 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BW9Y2D	Clematiunicinoside E	Investigative	11994185	C76H124O39	1661.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H](C8(C)C)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O[C@H]1[C@@H]([C@@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWI75Z	2-[3-(4-Bromophenyl)-1-phenylpyrazol-4-yl]-5-phenyl-1,3,4-oxadiazole	Investigative	46934255	C23H15BrN4O	443.3	C1=CC=C(C=C1)C2=NN=C(O2)C3=CN(N=C3C4=CC=C(C=C4)Br)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWK64U	Cussonoside A	Investigative	171596	C48H78O18	943.1	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWKQ39	(3R,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihydro-furan-2-one	Investigative	44323830	C17H16O4S	316.4	CS(=O)(=O)C1=CC=C(C=C1)[C@H]2COC(=O)[C@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWM30K	3-(5-Chlorofuran-2-yl)-5-phenyl-1,2-oxazole-4-carboxylic acid	Investigative	57780772	C14H8ClNO4	289.67	C1=CC=C(C=C1)C2=C(C(=NO2)C3=CC=C(O3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWOH67	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)naphthalene	Investigative	10762072	C23H17FO2S	376.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC3=CC=CC=C3C=C2C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BWUG40	1-(5-Chloro-1,3-benzoxazol-2-yl)-N-[(1S,2R)-2-phenylmethoxycyclopentyl]piperidine-4-carboxamide	Investigative	71521226	C25H28ClN3O3	454	C1C[C@@H]([C@@H](C1)OCC2=CC=CC=C2)NC(=O)C3CCN(CC3)C4=NC5=C(O4)C=CC(=C5)Cl	IC50 = 76600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX1Y8W	2-(4-Chlorophenyl)-5-[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]-1,3,4-oxadiazole	Investigative	90643446	C24H17ClN4O	412.9	CC1=CC=C(C=C1)C2=NN(C=C2C3=NN=C(O3)C4=CC=C(C=C4)Cl)C5=CC=CC=C5	IC50 = 58000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX29JL	3-Methyl-7-[(4-nitrophenyl)methyl]-5-[(4-phenyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)methyl]-[1,2]oxazolo[4,5-d]pyridazin-4-one	Investigative	70687604	C22H17N7O4S	475.5	CC1=NOC2=C1C(=O)N(N=C2CC3=CC=C(C=C3)[N+](=O)[O-])CC4=NNC(=S)N4C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX38TG	3-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propan-1-ol	Investigative	16125428	C19H18ClFN2O4S	424.9	CS(=O)(=O)C1=CC=C(C=C1)N2C=NC(=C2C3=CC(=C(C=C3)OCCCO)F)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX4I2F	3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid	Investigative	51346826	C14H10F3NO2	281.23	C1=CC(=CC(=C1)NC2=CC=C(C=C2)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX5MA2	2-[3-(4-Methylphenyl)-1-phenylpyrazol-4-yl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	90643445	C23H17N5O	379.4	CC1=CC=C(C=C1)C2=NN(C=C2C3=NN=C(O3)C4=CC=NC=C4)C5=CC=CC=C5	IC50 = 53000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX5R7G	2-Methyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline	Investigative	10947004	C17H17NO3S	315.4	CN1CC(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX7T9L	4-[3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide	Investigative	11316581	C19H19ClN2O6S	438.9	CC1=C(C(=NO1)C2=C(C(=C(C=C2OC)OC)Cl)OC)C3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BX9Z2M	Cauloside D	Investigative	21630094	C53H86O22	1075.2	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)[C@@]45CC[C@@]6(C(=CC[C@H]7[C@]6(CC[C@@H]8[C@@]7(CC[C@@H]([C@@]8(C)CO)O[C@H]9[C@@H]([C@H]([C@H](CO9)O)O)O)C)C)[C@@H]4CC(CC5)(C)C)C)O)O)O)CO)O)O)O	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BXAM45	2-[6-Chloro-9-(3-chlorobenzoyl)carbazol-2-yl]propanoic acid	Investigative	71455230	C22H15Cl2NO3	412.3	CC(C1=CC2=C(C=C1)C3=C(N2C(=O)C4=CC(=CC=C4)Cl)C=CC(=C3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BXD7Q8	N-[3-(2-Ethylphenylamino)-4-pyridinyl]methanesulfonamide	Investigative	44473492	C14H17N3O2S	291.37	CCC1=CC=CC=C1NC2=C(C=CN=C2)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BXH3D6	N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]methanesulfonamide	Investigative	11302033	C12H10Cl2N2O3S	333.2	CS(=O)(=O)NC1=C(C=NC=C1)OC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BXK6Z8	N-(3-Aminophenyl)-4-(trifluoromethyl)benzamide	Investigative	24695790	C14H11F3N2O	280.24	C1=CC(=CC(=C1)NC(=O)C2=CC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BXMZ29	2-(6-Chloro-9-hexoxycarbonylcarbazol-2-yl)propanoic acid	Investigative	71453519	C22H24ClNO4	401.9	CCCCCCOC(=O)N1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY0B9N	2-(Cyanoamino)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazol-4(5H)-one	Investigative	135430565	C19H23N3O2S	357.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C\\2/C(=O)NC(=NC#N)S2	IC50 = 55000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY0H7X	2-[4,5-Difluoro-2-(4-methylsulfonylphenyl)phenyl]-5-methylpyridine	Investigative	10522463	C19H15F2NO2S	359.4	CC1=CN=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)F)F	IC50 = 52300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY54XT	3-[5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propionic acid ethyl ester	Investigative	44330480	C22H21FO4S2	432.5	CCOC(=O)CCC1=CC(=C(S1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 130000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY57WS	(2E,5Z)-5-[(3,5-Ditert-butyl-4-hydroxyphenyl)methylidene]-2-ethoxyimino-1,3-oxazolidin-4-one	Investigative	135506078	C20H28N2O4	360.4	CCO/N=C/1\\NC(=O)/C(=C/C2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C)/O1	IC50 = 79000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY5UJ2	2-(4-Chlorophenyl)-5-[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]-1,3,4-oxadiazole	Investigative	90643447	C24H17ClN4O2	428.9	COC1=CC=C(C=C1)C2=NN(C=C2C3=NN=C(O3)C4=CC=C(C=C4)Cl)C5=CC=CC=C5	IC50 = 67000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY68CN	Osthole	Investigative	10228	C15H16O3	244.28	CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C	IC50 = 81100 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BY7AD6	3-[2-Nitro-4-(trifluoromethyl)anilino]benzoic acid	Investigative	4763963	C14H9F3N2O4	326.23	C1=CC(=CC(=C1)NC2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-])C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYAV26	4-Amino-N-(4-trifluoromethylphenyl)benzamide	Investigative	13609518	C14H11F3N2O	280.24	C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYD0P5	N-[3-Chloro-4-(4-chlorobenzoyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728409	C22H14Cl2N2O5S	489.3	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC(=C(C=C3)C(=O)C4=CC=C(C=C4)Cl)Cl)O	IC50 = 95600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYKL39	2-[4-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid	Investigative	122192743	C13H10F5NO2S	339.28	C1=CC=C(C(=C1)C(=O)O)NC2=CC=C(C=C2)S(F)(F)(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYL3T9	2-[4-[3-(Cyclohexylcarbamoyloxy)phenyl]-3-fluorophenyl]propanoic acid	Investigative	73054542	C22H24FNO4	385.4	CC(C1=CC(=C(C=C1)C2=CC(=CC=C2)OC(=O)NC3CCCCC3)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYN29G	Chembl4167707	Investigative	145955705	C22H20ClFN6O4	486.9	C1COCC(=O)N1C2=CC=C(C=C2)NC3=NC(=NC(=N3)Cl)OCCNC(=O)C4=CC=CC=C4F	IC50 = 70000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BYU27W	2-[3-Fluoro-4-[4-(hexylcarbamoyloxy)phenyl]phenyl]propanoic acid	Investigative	127031160	C22H26FNO4	387.4	CCCCCCNC(=O)OC1=CC=C(C=C1)C2=C(C=C(C=C2)C(C)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ04AL	Morusin	Investigative	5281671	C25H24O6	420.5	CC(=CCC1=C(OC2=C(C1=O)C(=CC3=C2C=CC(O3)(C)C)O)C4=C(C=C(C=C4)O)O)C	IC50 = 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ0PV1	4-[5-Tert-butyl-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid	Investigative	88930915	C19H21FN2O3S	376.4	CC(C)(C)C1=NN(C(C1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ0U4E	N-(3-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16774950	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ3M6H	2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline	Investigative	49805180	C18H22N2O2	298.4	C1CCN(C1)CCOC2=CC=C(C=C2)OC3=CC=CC=C3N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ3O2L	1-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole	Investigative	10664116	C18H16FNO2S	329.4	CCS(=O)(=O)C1=CC=C(C=C1)N2C=CC=C2C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZ97PY	[3-(2-Fluoro-4-methylphenyl)phenyl] N-hexylcarbamate	Investigative	127033540	C20H24FNO2	329.4	CCCCCCNC(=O)OC1=CC=CC(=C1)C2=C(C=C(C=C2)C)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZB16W	2-(Benzenesulfonyl)-3-naphthalen-2-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706113	C20H15F3N2O2S	404.4	C1C(N(N=C1C(F)(F)F)S(=O)(=O)C2=CC=CC=C2)C3=CC4=CC=CC=C4C=C3	IC50 = 173600 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZI80J	5-(4-Fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid	Investigative	10666285	C16H12FN3O4S	361.3	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZLV20	[(1S,2S,6R,10S,11R,13S,14R,15R)-14-Acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylpropanoate	Investigative	118727929	C26H36O8	476.6	C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)OC(=O)C(C)C)OC(=O)C	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	BZQ31A	N-(4-Aminophenyl)-2-(trifluoromethyl)benzamide	Investigative	16777326	C14H11F3N2O	280.24	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D00VHS	4-(5-(4-Hydroxyphenyl)isothiazol-4-yl)phenol	Investigative	136036233	C15H11NO2S	269.3	.	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D00XIX	5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiol-3-one	Investigative	44564003	C16H11ClOS2	318.8	CC1=CC=C(C=C1)C2=C(SSC2=O)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D01PBO	(+)-3,3'-bisdemethyltanegool	Investigative	44423052	C18H20O7	348.3	C1[C@@H]([C@H]([C@H](O1)C2=CC(=C(C=C2)O)O)CO)[C@@H](C3=CC(=C(C=C3)O)O)O	IC50 = 73900 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D03NMM	AM-643	Investigative	46843035	C36H39N4NaO4S	646.8	CC1=CN=C(C=C1)COC2=CC3=C(C=C2)N(C(=C3SC(C)(C)C)CC(C)(C)C(=O)[O-])CC4=CC=C(C=C4)C5=NC=C(C=N5)OC.[Na+]	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D03TLR	5-(4-Chlorophenyl)-4-p-tolylisothiazole	Investigative	44564454	C16H12ClNS	285.8	CC1=CC=C(C=C1)C2=C(SN=C2)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D05QOR	SCOPOLETIN	Investigative	5280460	C10H8O4	192.17	COC1=C(C=C2C(=C1)C=CC(=O)O2)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D06TPF	PYROGALLOL	Investigative	1057	C6H6O3	126.11	C1=CC(=C(C(=C1)O)O)O	IC50 = 144000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D06YGF	Caffeic acid phenethyl ester	Investigative	5281787	C17H16O4	284.31	C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 82000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D06ZRX	OXYRESVERATROL	Investigative	5281717	C14H12O4	244.24	C1=CC(=C(C=C1O)O)/C=C/C2=CC(=CC(=C2)O)O	IC50 = 109000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D07LUJ	URSOLIC ACID	Investigative	64945	C30H48O3	456.7	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O	IC50 = 86000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D07OAV	5-(2-1H-indenyl)-1,3-benzodioxole	Investigative	44424411	C16H12O2	236.26	C1C2=CC=CC=C2C=C1C3=CC4=C(C=C3)OCO4	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D08RCQ	5-(4-Methoxyphenyl)-4-p-tolylisothiazole	Investigative	44564416	C17H15NOS	281.4	CC1=CC=C(C=C1)C2=C(SN=C2)C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0E0RW	ISOSCOPOLETIN	Investigative	69894	C10H8O4	192.17	COC1=C(C=C2C=CC(=O)OC2=C1)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0G3TK	KAEMPFEROL	Investigative	5280863	C15H10O6	286.24	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0G7RA	4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiol-3-one	Investigative	44564004	C16H11ClOS2	318.8	CC1=CC=C(C=C1)C2=C(C(=O)SS2)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0L6TP	N-(3-phenoxy-4-pyridinyl)propanesulfonamide	Investigative	11277773	C14H16N2O3S	292.36	CCCS(=O)(=O)NC1=C(C=NC=C1)OC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0M5MI	SC-560	Investigative	4306515	C17H12ClF3N2O	352.7	COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl	IC50 = 74900 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0N7OP	2-(2-methoxyphenyl)-1H-indene	Investigative	44424412	C16H14O	222.28	COC1=CC=CC=C1C2=CC3=CC=CC=C3C2	IC50 = 62300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0N7XM	(-)-3,3'-bisdemethylpinoresinol	Investigative	24992964	C18H18O6	330.3	C1[C@@H]2[C@@H](CO[C@H]2C3=CC(=C(C=C3)O)O)[C@@H](O1)C4=CC(=C(C=C4)O)O	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0NH1E	Org-231295	Investigative	1383884	C20H22N2O3	338.4	C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0PQ3Q	4-(4-Chlorophenyl)-5-(4-methoxyphenyl)isothiazole	Investigative	44564458	C16H12ClNOS	301.8	COC1=CC=C(C=C1)C2=C(C=NS2)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0SJ2Q	OLEANOLIC_ACID	Investigative	10494	C30H48O3	456.7	C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O	IC50 = 87000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0V7AA	CATECHIN	Investigative	9064	C15H14O6	290.27	C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O	IC50 = 93300 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0V9EN	3,4-Dihydroxycinnamic Acid	Investigative	689043	C9H8O4	180.16	C1=CC(=C(C=C1/C=C/C(=O)O)O)O	IC50 = 129700 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0VF6F	N-(3-phenoxypyridin-4-yl)methanesulfonamide	Investigative	10244543	C12H12N2O3S	264.3	CS(=O)(=O)NC1=C(C=NC=C1)OC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66665	Prostaglandin G/H synthase 2	D0Y1YR	gingerol	Investigative	442793	C17H26O4	294.4	CCCCC[C@@H](CC(=O)CCC1=CC(=C(C=C1)O)OC)O	IC50 = 125000 nM	Poor binder