TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T66925	Coagulation factor XIIIA	D0UR1H	Peptide analog 54	Patented	71459385	C27H33ClN4O4	513	C=CC(=O)NCCCC[C@@H](C(=O)N1CCN(CC1)C2=CC=CC=C2Cl)NC(=O)OCC3=CC=CC=C3	IC50 = 67000 nM	Poor binder
T66925	Coagulation factor XIIIA	B2QH3D	Tert-butyl 4-[4-[[(E)-2-methylbut-2-enoyl]amino]phenyl]sulfonylpiperazine-1-carboxylate	Investigative	56954504	C20H29N3O5S	423.5	C/C=C(\\C)/C(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C(=O)OC(C)(C)C	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	B32PHT	Tert-butyl 2-[[(2S)-2-(phenylmethoxycarbonylamino)-6-(prop-2-enoylamino)hexanoyl]amino]acetate	Investigative	71450343	C23H33N3O6	447.5	CC(C)(C)OC(=O)CNC(=O)[C@H](CCCCNC(=O)C=C)NC(=O)OCC1=CC=CC=C1	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	B3Q0YV	Methyl (2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(E,2S)-6-methylsulfonyl-2-(phenylmethoxycarbonylamino)hex-5-enoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoate	Investigative	58435684	C32H47N5O10S	693.8	CC(C)C[C@@H](C(=O)OC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC/C=C/S(=O)(=O)C)NC(=O)OCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T66925	Coagulation factor XIIIA	B6HR7O	Tert-butyl 4-[4-[[(Z)-but-2-enoyl]amino]phenyl]sulfonylpiperazine-1-carboxylate	Investigative	56954502	C19H27N3O5S	409.5	C/C=C\\C(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C(=O)OC(C)(C)C	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	B93JXQ	Tert-butyl 4-(4-cyanophenyl)sulfonylpiperazine-1-carboxylate	Investigative	6736443	C16H21N3O4S	351.4	CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C#N	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	B9UR7J	Ethyl (E,6S)-7-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-methoxy-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-7-oxo-6-(phenylmethoxycarbonylamino)hept-2-enoate	Investigative	71096277	C34H49N5O10	687.8	CCOC(=O)/C=C/CC[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)OC)NC(=O)OCC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T66925	Coagulation factor XIIIA	BAM17L	(2S)-1-Acetyl-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-6-diazo-1,5-dioxohexan-2-yl]pyrrolidine-2-carboxamide	Investigative	136233424	C33H46N8O7	666.8	CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N)NC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@@H]3CCCN3C(=O)C	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	BJC4G6	Benzyl 4-[3-[methyl(2-methylpropyl)amino]-4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate	Investigative	56954825	C26H34N4O5S	514.6	CC(C)CN(C)C1=C(C=CC(=C1)S(=O)(=O)N2CCN(CC2)C(=O)OCC3=CC=CC=C3)NC(=O)C=C	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	BJF9A1	(2S)-6-(1,3-Diethyl-4,5-dimethylimidazol-1-ium-2-yl)sulfanyl-5-oxo-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]hexanoic acid;bromide	Investigative	72204898	C32H41BrN4O6S	689.7	CCN1C(=C([N+](=C1SCC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)CC)C)C.[Br-]	IC50 = 50000 nM	Poor binder
T66925	Coagulation factor XIIIA	BMW1X7	Tert-butyl 4-[4-(2-methylprop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate	Investigative	56954418	C19H27N3O5S	409.5	CC(=C)C(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C(=O)OC(C)(C)C	IC50 ~ 80000 nM	Poor binder
T66925	Coagulation factor XIIIA	BNX95R	N-Hexyl-2-nitrobenzenesulfonamide	Investigative	2836767	C12H18N2O4S	286.35	CCCCCCNS(=O)(=O)C1=CC=CC=C1[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66925	Coagulation factor XIIIA	BOQ79Z	[(5S)-5-Carboxy-2-oxo-5-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentyl]-dimethylsulfanium;bromide	Investigative	11433027	C25H31BrN2O6S	567.5	C[S+](C)CC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2.[Br-]	IC50 = 105000 nM	Poor binder
T66925	Coagulation factor XIIIA	BQC43P	2-Nitro-N-[6-(3-nitro-pyridin-2-ylamino)-hexyl]-benzenesulfonamide	Investigative	11430157	C17H21N5O6S	423.4	C1=CC=C(C(=C1)[N+](=O)[O-])S(=O)(=O)NCCCCCCNC2=C(C=CC=N2)[N+](=O)[O-]	IC50 = 170000 nM	Poor binder
T66925	Coagulation factor XIIIA	BW3Y2M	Ethyl (E,6S)-7-[[(2S)-1-[(2S)-2-[[(2S)-1-methoxy-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-7-oxo-6-(phenylmethoxycarbonylamino)hept-2-enoate	Investigative	44177708	C34H50N4O9	658.8	CCOC(=O)/C=C/CC[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)OC)NC(=O)OCC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T66925	Coagulation factor XIIIA	BZ8J1U	Benzyl 4-[2-(prop-2-enoylamino)pyrimidin-5-yl]sulfonylpiperazine-1-carboxylate	Investigative	56954413	C19H21N5O5S	431.5	C=CC(=O)NC1=NC=C(C=N1)S(=O)(=O)N2CCN(CC2)C(=O)OCC3=CC=CC=C3	IC50 ~ 80000 nM	Poor binder