TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T66935 Poly [ADP-ribose] glycohydrolase B0V8IC N-Ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Investigative 1517285 C12H15N3O4S 297.33 CCNS(=O)(=O)C1=CC2=C(C=C1)N(C(=O)N(C2=O)C)C EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B2EI4P N,1,3-Triethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Investigative 4093912 C14H19N3O4S 325.39 CCNS(=O)(=O)C1=CC2=C(C=C1)N(C(=O)N(C2=O)CC)CC EC50 = 140000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B37XZO Chembl4279825 Investigative 145981912 C14H19N3O4S 325.39 CC(C)(C)NS(=O)(=O)C1=CC2=C(C=C1)N(C(=O)N(C2=O)C)C EC50 = 110000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B4OK5I 3,5-Dichloro-N-(3-chloro-4-naphthalen-2-yloxyphenyl)-2-hydroxybenzamide Investigative 53387188 C23H14Cl3NO3 458.7 C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=C(C(=CC(=C4)Cl)Cl)O)Cl EC50 ~ 70000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B5G2NT Chembl4279279 Investigative 145982111 C17H14N2O5S 358.4 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C=C(C=C3)S(=O)(=O)NCCC(=O)N EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B5YGM4 2-{[(Tert-butyl)amino]sulfonyl}anthracene-9,10-dione Investigative 2829333 C18H17NO4S 343.4 CC(C)(C)NS(=O)(=O)C1=CC2=C(C=C1)C(=O)C3=CC=CC=C3C2=O EC50 = 81000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B63ANU Chembl4287896 Investigative 145993165 C14H15NO2S 261.339 CC1(CC1)NS(=O)(=O)C2=CC3=CC=CC=C3C=C2 EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B7GZ8Q 2-[(3-Chloro-4-naphthalen-2-yloxyphenyl)carbamoyl]benzoic acid Investigative 56658117 C24H16ClNO4 417.8 C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=CC=CC=C4C(=O)O)Cl IC50 = 72000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase B9IYK3 Chembl4278137 Investigative 145981393 C20H27N3O4S 405.5 CC1(CC1)NS(=O)(=O)C2=CC3=C(C=C2)N(C(=O)N(C3=O)CC4CCCCC4)C EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BB8T3R 3-{(5z)-5-[5-Chloro-1-(2,6-Dichlorobenzyl)-2-Oxo-1,2-Dihydro-3h-Indol-3-Ylidene]-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl}propanoic Acid Investigative 76850155 C21H13Cl3N2O4S2 527.8 C1=CC(=C(C(=C1)Cl)CN2C3=C(C=C(C=C3)Cl)/C(=C/4\\C(=O)N(C(=S)S4)CCC(=O)O)/C2=O)Cl EC50 ~ 70000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BC06MW 3,5-Dichloro-N-(3-chloro-4-naphthalen-2-yloxyphenyl)-2-hydroxy-N-methylbenzamide Investigative 53392780 C24H16Cl3NO3 472.7 CN(C1=CC(=C(C=C1)OC2=CC3=CC=CC=C3C=C2)Cl)C(=O)C4=C(C(=CC(=C4)Cl)Cl)O IC50 = 140000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BEW1P9 3,5-Dichloro-N-(3-chloro-4-phenoxyphenyl)-2-hydroxybenzamide Investigative 53391636 C19H12Cl3NO3 408.7 C1=CC=C(C=C1)OC2=C(C=C(C=C2)NC(=O)C3=C(C(=CC(=C3)Cl)Cl)O)Cl IC50 = 61000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BMF09V Chembl4294973 Investigative 46361427 C13H16N2O3S 280.34 CC(C)(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=O)C=C2 EC50 = 110000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BNG13F Chembl4284330 Investigative 5300082 C15H20N2O3S 308.4 CC1=CC(=O)N(C2=C1C=C(C=C2)S(=O)(=O)NC(C)(C)C)C EC50 = 57000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BO5NT1 Chembl4287526 Investigative 7122772 C16H13NO5S 331.3 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C=C(C=C3)S(=O)(=O)NCCO EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BOMB68 3-Chloro-N-(3-chloro-4-naphthalen-2-yloxyphenyl)-2-hydroxybenzamide Investigative 53392961 C23H15Cl2NO3 424.3 C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=C(C(=CC=C4)Cl)O)Cl IC50 = 61000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BORI56 Chembl4291914 Investigative 3870576 C18H15NO4S 341.4 C1CC(C1)NS(=O)(=O)C2=CC3=C(C=C2)C(=O)C4=CC=CC=C4C3=O EC50 ~ 50000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BP5I8T 5-Chloro-N-(3-chloro-4-naphthalen-2-yloxyphenyl)-2-hydroxybenzamide Investigative 53392960 C23H15Cl2NO3 424.3 C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=C(C=CC(=C4)Cl)O)Cl IC50 = 117000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BPMV37 Chembl4287413 Investigative 145991145 C16H12N2O5S 344.3 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C=C(C=C3)S(=O)(=O)NCC(=O)N EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BTJG82 2-Phenanthridinesulfonamide, N-cyclopropyl-5,6-dihydro-6-oxo- Investigative 6324454 C16H14N2O3S 314.4 C1CC1NS(=O)(=O)C2=CC3=C(C=C2)NC(=O)C4=CC=CC=C43 EC50 = 50000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BU41YT Chembl4294224 Investigative 145994151 C19H19NO5S 373.4 CC(C)(COC)NS(=O)(=O)C1=CC2=C(C=C1)C(=O)C3=CC=CC=C3C2=O EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BX2EB5 Chembl4283645 Investigative 7164286 C17H15NO5S 345.4 COCCNS(=O)(=O)C1=CC2=C(C=C1)C(=O)C3=CC=CC=C3C2=O EC50 ~ 150000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BX46WT Chembl4287243 Investigative 16832109 C16H13NO4S 315.3 CCNS(=O)(=O)C1=CC2=C(C=C1)C(=O)C3=CC=CC=C3C2=O EC50 = 110000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BXW82A Chembl4286999 Investigative 145991355 C17H12N2O4S 340.4 C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C=C(C=C3)S(=O)(=O)NCCC#N EC50 = 88000 nM Poor binder T66935 Poly [ADP-ribose] glycohydrolase BZJ9E2 N-Tert-butylnaphthalene-2-sulfonamide Investigative 873742 C14H17NO2S 263.36 CC(C)(C)NS(=O)(=O)C1=CC2=CC=CC=C2C=C1 EC50 ~ 150000 nM Poor binder