TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67849	PI3-kinase delta	D0W5HK	Sorafenib	Approved	216239	C21H16ClF3N4O3	464.8	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	D01RYO	Gefitinib	Patented	123631	C22H24ClFN4O3	446.9	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	D0DF2M	PMID28870136-Compound-48	Patented	2153	C7H8N4O2	180.16	CN1C2=C(C(=O)N(C1=O)C)NC=N2	IC50 = 75000 nM	Poor binder
T67849	PI3-kinase delta	D0H9IX	PMID28870136-Compound-52	Patented	2519	C8H10N4O2	194.19	CN1C=NC2=C1C(=O)N(C(=O)N2C)C	IC50 = 75000 nM	Poor binder
T67849	PI3-kinase delta	B0BPU7	3-(2-Acetamido-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-methylbenzamide	Investigative	25129024	C16H15N5O2	309.32	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC(=CC=C3)C(=O)NC	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B0EYR7	3-(3-Aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905260	C11H10N6	226.24	C1=CC(=CC(=C1)N)C2=C3C(=NC=NC3=NN2)N	IC50 = 82000 nM	Poor binder
T67849	PI3-kinase delta	B0H6BQ	8-Chloro-6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine	Investigative	66552523	C12H10ClN5O2S	323.76	CS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)Cl	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B0P6IU	(R)-2-(3-Benzylmorpholino)-5,5-dimethyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578074	C20H24N2O2S	356.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@H]3CC4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B0VJ2O	N-(6-Isoquinolin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide	Investigative	66552347	C17H13N5O	303.32	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CN=CC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B25PQC	N,N-Dimethyl-6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine	Investigative	59477038	C14H15N5O2S	317.37	CN(C)C1=NN2C=C(C=CC2=N1)C3=CC(=CN=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B2OF9R	3-(4-Nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905261	C11H8N6O2	256.22	C1=CC(=CC=C1C2=C3C(=NC=NC3=NN2)N)[N+](=O)[O-]	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B2Q0OV	2,11-Dichloro-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118728325	C15H10Cl2N2O	305.2	C1COC2=C(C=C(C=C2)Cl)C3=NC4=C(N31)C=CC(=C4)Cl	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B2S0VM	1-Tert-Butyl-3-Naphthalen-2-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine	Investigative	5059890	C19H19N5	317.4	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=CC=CC=C4C=C3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B38XJN	N-(6-Pyridin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide	Investigative	25133144	C13H11N5O	253.26	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B3PC8Y	11-Fluoro-2-methyl-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118728320	C16H13FN2O	268.28	CC1=CC2=C(C=C1)OCCN3C2=NC4=C3C=CC(=C4)F	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B3U2MN	N-[6-(1-Methylpyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552407	C12H12N6O	256.26	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CN(N=C3)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B3VMU7	N-Acetyl-N-[5-(4-morpholin-4-ylpyrido[3,2-d]pyrimidin-2-yl)pyrimidin-2-yl]acetamide	Investigative	76324822	C19H19N7O3	393.4	CC(=O)N(C1=NC=C(C=N1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3)C(=O)C	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B4CWO6	(S)-5,5-Dimethyl-2-(3-phenylmorpholino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578040	C19H22N2O2S	342.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@@H]3C4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B4DF6B	2-Bromo-11-fluoro-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118728322	C15H10BrFN2O	333.15	C1COC2=C(C=C(C=C2)Br)C3=NC4=C(N31)C=CC(=C4)F	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B4HX3I	1-Isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905171	C12H13N7	255.28	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CN=CN=C3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B57MKH	N-[5-[3-(2-Hydroxyethylsulfamoyl)-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide	Investigative	127031333	C18H25N3O5S2	427.5	CC1=C(SC(=N1)NC(=O)C(C)(C)C)C2=CC(=C(C=C2)OC)S(=O)(=O)NCCO	IC50 = 50000 nM	Poor binder
T67849	PI3-kinase delta	B57WNT	6-Oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile	Investigative	131989	C11H7N3O	197.19	C1=CN=CC=C1C2=CNC(=O)C(=C2)C#N	IC50 = 65700 nM	Poor binder
T67849	PI3-kinase delta	B58GCW	4-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	42606078	C15H11N3	233.27	C1=CC2=C(NN=C2C=C1)C#CC3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B59FVI	2-(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenol	Investigative	135947977	C11H9N5O	227.22	C1=CC=C(C(=C1)C2=C3C(=NC=NC3=NN2)N)O	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B63WDX	1-Methyl-3-(4-phenylmethoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	52942202	C19H17N5O	331.4	CN1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)OCC4=CC=CC=C4)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B6CXI2	1-(Cyclopropylmethyl)-4-[2-(oxan-4-ylmethylamino)-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184540	C22H25N3O2S	395.5	C1CC1CN2C=CC(=CC2=O)C3=CC4=C(C=C3)N=C(S4)NCC5CCOCC5	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B6LVO3	N-[6-[4-(Methylsulfamoyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552298	C15H15N5O3S	345.4	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=C(C=C3)S(=O)(=O)NC	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B7D0OZ	1-(Cyclopropylmethyl)-4-[2-[[(1R)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184541	C23H27N3O2S	409.5	C[C@H](C1CCOCC1)NC2=NC3=C(S2)C=C(C=C3)C4=CC(=O)N(C=C4)CC5CC5	IC50 ~ 199526.23 nM	Poor binder
T67849	PI3-kinase delta	B7XED2	2-(Pyridin-4-yl)benzo[d]oxazol-5-ol	Investigative	4912089	C12H8N2O2	212.2	C1=CC2=C(C=C1O)N=C(O2)C3=CC=NC=C3	IC50 ~ 83300 nM	Poor binder
T67849	PI3-kinase delta	B81ZOJ	N-[6-(3-Phenylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552345	C20H16N4O	328.4	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=CC(=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B89CGE	3-(1-Isopropyl-4-(methylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenol	Investigative	24905257	C15H17N5O	283.33	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=CC=C3)O)NC	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	B8GKJ5	3-[2-(4-Methoxyphenyl)ethynyl]-5-morpholin-4-ylthieno[3,2-b]pyran-7-one	Investigative	44180282	C20H17NO4S	367.4	COC1=CC=C(C=C1)C#CC2=CSC3=C2OC(=CC3=O)N4CCOCC4	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	B8SKH9	11-(4-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180796	C26H27N5O2S	473.6	COC1=CC=C(C=C1)C2=NC(=C3C4CCCN4C(=S)N(C3=N2)C5=CC=CC=C5)N6CCOCC6	IC50 = 56890 nM	Poor binder
T67849	PI3-kinase delta	B8XKP6	N-[6-(2,4-Dimethyl-1,3-thiazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552348	C13H13N5OS	287.34	CC1=C(SC(=N1)C)C2=CN3C(=NC(=N3)NC(=O)C)C=C2	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	B8ZND1	5-(2-Amino-7-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide	Investigative	66552524	C15H17FN6O2S	364.4	CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C=C2F	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BA1EL4	3-(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)-N-phenylpropanamide	Investigative	2988969	C16H13ClN2O3	316.74	C1=CC=C(C=C1)NC(=O)CCN2C3=C(C=C(C=C3)Cl)OC2=O	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BB1E5A	(R)-5,5-Dimethyl-2-(3-phenylmorpholino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578039	C19H22N2O2S	342.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@H]3C4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BBCR35	3-(1,2,3,4-Tetrahydronaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905268	C15H15N5	265.31	C1CC2=CC=CC=C2CC1C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BBRF19	4-(5-Morpholin-4-yl-7-oxothieno[3,2-b]pyran-3-yl)benzonitrile	Investigative	44181599	C18H14N2O3S	338.4	C1COCCN1C2=CC(=O)C3=C(O2)C(=CS3)C4=CC=C(C=C4)C#N	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BBV89X	4-[2-(3-Methoxyphenyl)pyrido[3,2-d]pyrimidin-4-yl]morpholine	Investigative	76317467	C18H18N4O2	322.4	COC1=CC=CC(=C1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BBWU45	6-(4-Amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905227	C19H18N6O	346.4	C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)NC(=O)C=C5)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BC23WJ	3-(H-Imidazo[1,2-a]pyridin-7-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905246	C15H15N7	293.33	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=NC=CN4C=C3)N	IC50 = 72000 nM	Poor binder
T67849	PI3-kinase delta	BC7R5H	5-(2-Amino-1,3-benzothiazol-6-yl)-N,N-dimethylpyridine-2-carboxamide	Investigative	122184479	C15H14N4OS	298.4	CN(C)C(=O)C1=NC=C(C=C1)C2=CC3=C(C=C2)N=C(S3)N	IC50 = 63095.73 nM	Poor binder
T67849	PI3-kinase delta	BD20YU	N-(6-Pyrimidin-5-yl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide	Investigative	25129729	C12H10N6O	254.25	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CN=CN=C3	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BD4NB2	N-Methyl-N-[6-(3-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552410	C16H16N4O3S	344.4	CC(=O)N(C)C1=NN2C=C(C=CC2=N1)C3=CC(=CC=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BD6AQ8	1-(Cyclopropylmethyl)-4-[2-[[(1S)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184542	C23H27N3O2S	409.5	C[C@@H](C1CCOCC1)NC2=NC3=C(S2)C=C(C=C3)C4=CC(=O)N(C=C4)CC5CC5	IC50 ~ 199526.23 nM	Poor binder
T67849	PI3-kinase delta	BDR9I6	1-(Cyclopropylmethyl)-4-[2-[(1,1-dioxothian-4-yl)methylamino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184543	C22H25N3O3S2	443.6	C1CC1CN2C=CC(=CC2=O)C3=CC4=C(C=C3)N=C(S4)NCC5CCS(=O)(=O)CC5	IC50 ~ 199526.23 nM	Poor binder
T67849	PI3-kinase delta	BEFY06	2-Bromo-11-chloro-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118728326	C15H10BrClN2O	349.61	C1COC2=C(C=C(C=C2)Br)C3=NC4=C(N31)C=CC(=C4)Cl	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BENP95	4-(2-Pyridin-3-ylpyrido[3,2-d]pyrimidin-4-yl)morpholine	Investigative	76317468	C16H15N5O	293.32	C1COCCN1C2=NC(=NC3=C2N=CC=C3)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BF35LM	1-Methyl-3-(3-phenylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	52944356	C18H15N5	301.3	CN1C2=NC=NC(=C2C(=N1)C3=CC=CC(=C3)C4=CC=CC=C4)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BFQ45P	trans-4-[[[6-[1-(Cyclopropylmethyl)-1,2-dihydro-2-oxo-4-pyridinyl]-2-benzothiazolyl]amino]methyl]-cyclohexanecarboxylic acid	Investigative	122184544	C24H27N3O3S	437.6	C1CC(CCC1CNC2=NC3=C(S2)C=C(C=C3)C4=CC(=O)N(C=C4)CC5CC5)C(=O)O	IC50 ~ 79432.82 nM	Poor binder
T67849	PI3-kinase delta	BFW82C	6-Pyridin-2-yl-1,3-benzothiazol-2-amine	Investigative	122184481	C12H9N3S	227.29	C1=CC=NC(=C1)C2=CC3=C(C=C2)N=C(S3)N	IC50 = 79432.82 nM	Poor binder
T67849	PI3-kinase delta	BGPS06	N-[7-Methyl-6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552467	C15H15N5O3S	345.4	CC1=CC2=NC(=NN2C=C1C3=CC(=CN=C3)S(=O)(=O)C)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BGUS85	11-(3-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180795	C26H27N5O2S	473.6	COC1=CC=CC(=C1)C2=NC(=C3C4CCCN4C(=S)N(C3=N2)C5=CC=CC=C5)N6CCOCC6	IC50 = 71350 nM	Poor binder
T67849	PI3-kinase delta	BGWU68	5-Morpholino-3-(pyridin-3-yl)-7H-thieno[3,2-b]pyran-7-one	Investigative	44181493	C16H14N2O3S	314.4	C1COCCN1C2=CC(=O)C3=C(O2)C(=CS3)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BH1ZW0	2-[5-[(3-Methoxyphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]-5-methylphenol	Investigative	136254187	C17H16N2O3S	328.4	CC1=CC(=C(C=C1)C2=NN=C(O2)SCC3=CC(=CC=C3)OC)O	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BH8LE3	2-Pyridin-4-yl-benzooxazol-5-ylamine	Investigative	736009	C12H9N3O	211.22	C1=CC2=C(C=C1N)N=C(O2)C3=CC=NC=C3	IC50 ~ 83300 nM	Poor binder
T67849	PI3-kinase delta	BJ6Z0V	2-Methyl-11-(trifluoromethyl)-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118728336	C17H13F3N2O	318.29	CC1=CC2=C(C=C1)OCCN3C2=NC4=C3C=CC(=C4)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BJ93VR	2-[4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenyl]acetonitrile	Investigative	134146051	C18H16N4O2	320.3	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)CC#N)OC	IC50 = 55000 nM	Poor binder
T67849	PI3-kinase delta	BJF52U	3-(4-Thiomorpholin-4-ylpyrido[3,2-d]pyrimidin-2-yl)phenol	Investigative	76335666	C17H16N4OS	324.4	C1CSCCN1C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BL8T7P	2,11-Dimethyl-6,7-dihydrobenzimidazolo[1,2-d][1,4]benzoxazepine	Investigative	118730033	C17H16N2O	264.32	CC1=CC2=C(C=C1)OCCN3C2=NC4=C3C=CC(=C4)C	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BLY40Q	3-[4-(4,4-Difluoropiperidin-1-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76335667	C18H16F2N4O	342.3	C1CN(CCC1(F)F)C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BM24CI	3-(3-(2,6-Dichlorobenzyloxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905265	C18H13Cl2N5O	386.2	C1=CC(=CC(=C1)OCC2=C(C=CC=C2Cl)Cl)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BM4IQ7	5-[[(5,6-Dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]methyl]-2-furancarboxylic acid methyl ester	Investigative	2612441	C15H14N2O3S2	334.4	CC1=C(SC2=C1C(=NC=N2)SCC3=CC=C(O3)C(=O)OC)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BM76KW	8-Methyl-7-[2-(4-methylpiperazin-1-yl)ethoxy]-2-morpholin-4-yl-1,3-benzoxazin-4-one	Investigative	17756679	C20H28N4O4	388.5	CC1=C(C=CC2=C1OC(=NC2=O)N3CCOCC3)OCCN4CCN(CC4)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BMGN80	6-Pyrimidin-2-yl-1,3-benzothiazol-2-amine	Investigative	122184482	C11H8N4S	228.28	C1=CN=C(N=C1)C2=CC3=C(C=C2)N=C(S3)N	IC50 = 50118.72 nM	Poor binder
T67849	PI3-kinase delta	BNT01I	4-(2-Amino-1,3-benzothiazol-6-yl)-1-(2-methoxyethoxy)pyridin-2-one	Investigative	122184539	C15H15N3O3S	317.4	COCCON1C=CC(=CC1=O)C2=CC3=C(C=C2)N=C(S3)N	IC50 ~ 199526.23 nM	Poor binder
T67849	PI3-kinase delta	BNX13Z	6-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905226	C17H16N6O	320.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)NC(=O)C=C4)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BOM52F	6-[6-(Methylaminomethyl)pyridin-3-yl]-1,3-benzothiazol-2-amine	Investigative	122184468	C14H14N4S	270.35	CNCC1=NC=C(C=C1)C2=CC3=C(C=C2)N=C(S3)N	IC50 = 63095.73 nM	Poor binder
T67849	PI3-kinase delta	BPQ0R9	N-[6-(3-Methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	25128668	C15H14N4O2	282.3	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC(=CC=C3)OC	IC50 ~ 79432.82 nM	Poor binder
T67849	PI3-kinase delta	BPZA98	4-[2-(4-Methoxyphenyl)pyrido[3,2-d]pyrimidin-4-yl]morpholine	Investigative	76313939	C18H18N4O2	322.4	COC1=CC=C(C=C1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BQ2BT1	13-Morpholin-4-yl-11-(morpholin-4-ylmethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180839	C24H30N6O2S	466.6	C1CC2C3=C(N=C(N=C3N(C(=S)N2C1)C4=CC=CC=C4)CN5CCOCC5)N6CCOCC6	IC50 = 120000 nM	Poor binder
T67849	PI3-kinase delta	BR0Y9C	3-[4-(4-Methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76310247	C18H19N5O	321.4	CN1CCN(CC1)C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BT6N0R	3-(3-Phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905262	C17H13N5O	303.32	C1=CC=C(C=C1)OC2=CC=CC(=C2)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BT7B6U	3-[4-(1,1-Dioxo-1,4-thiazinan-4-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76317466	C17H16N4O3S	356.4	C1CS(=O)(=O)CCN1C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BV36FK	5-Morpholin-4-ylthieno[3,2-b]pyran-7-one	Investigative	44181603	C11H11NO3S	237.28	C1COCCN1C2=CC(=O)C3=C(O2)C=CS3	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BW34XQ	N-[6-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552297	C15H14N4O3S	330.4	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BWQN23	3-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	42606076	C15H11N3	233.27	C1=CC2=C(NN=C2C=C1)C#CC3=CC(=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BWS24D	3-(4-Biphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905267	C17H13N5	287.32	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T67849	PI3-kinase delta	BX5CQ8	6-(5-Methylsulfonylpyridin-3-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine	Investigative	66552468	C13H10F3N5O2S	357.31	CS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BX9A4E	3-(Furan-3-yl)-5-morpholin-4-ylthieno[3,2-b]pyran-7-one	Investigative	44180155	C15H13NO4S	303.3	C1COCCN1C2=CC(=O)C3=C(O2)C(=CS3)C4=COC=C4	IC50 ~ 50000 nM	Poor binder
T67849	PI3-kinase delta	BXP7W4	N-[6-(5-Methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]methanesulfonamide	Investigative	66552412	C13H13N5O4S2	367.4	CS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)NS(=O)(=O)C)C=C2	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BYQ5V8	2-[5-[(3-Chlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]-5-methoxyphenol	Investigative	136254188	C16H13ClN2O3S	348.8	COC1=CC(=C(C=C1)C2=NN=C(O2)SCC3=CC(=CC=C3)Cl)O	IC50 ~ 100000 nM	Poor binder
T67849	PI3-kinase delta	BZ42BQ	13-Morpholin-4-yl-11-(1-morpholin-4-ylethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180840	C25H32N6O2S	480.6	CC(C1=NC(=C2C3CCCN3C(=S)N(C2=N1)C4=CC=CC=C4)N5CCOCC5)N6CCOCC6	IC50 = 154780 nM	Poor binder