TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T68544 Estrogen-related receptor alpha B4RL9Q (2-Aminophenyl)-[1-(3-phenylmethoxyphenyl)triazol-4-yl]methanone Investigative 71682010 C22H18N4O2 370.4 C1=CC=C(C=C1)COC2=CC=CC(=C2)N3C=C(N=N3)C(=O)C4=CC=CC=C4N IC50 ~ 50000 nM Poor binder T68544 Estrogen-related receptor alpha BF4HZ2 3-[4-(2-Aminobenzoyl)triazol-1-yl]benzoic acid Investigative 71682016 C16H12N4O3 308.29 C1=CC=C(C(=C1)C(=O)C2=CN(N=N2)C3=CC=CC(=C3)C(=O)O)N IC50 ~ 50000 nM Poor binder T68544 Estrogen-related receptor alpha BH3LP1 [1-(4-Propan-2-ylphenyl)triazol-4-yl]-[2-(trifluoromethyl)phenyl]methanone Investigative 71681678 C19H16F3N3O 359.3 CC(C)C1=CC=C(C=C1)N2C=C(N=N2)C(=O)C3=CC=CC=C3C(F)(F)F IC50 ~ 50000 nM Poor binder T68544 Estrogen-related receptor alpha BW0C2B 3-[4-(2-Aminobenzoyl)triazol-1-yl]benzenesulfonamide Investigative 71682015 C15H13N5O3S 343.4 C1=CC=C(C(=C1)C(=O)C2=CN(N=N2)C3=CC(=CC=C3)S(=O)(=O)N)N IC50 ~ 50000 nM Poor binder T68544 Estrogen-related receptor alpha BWAR38 3-[4-(2-Aminobenzoyl)triazol-1-yl]benzonitrile Investigative 71682014 C16H11N5O 289.29 C1=CC=C(C(=C1)C(=O)C2=CN(N=N2)C3=CC=CC(=C3)C#N)N IC50 ~ 50000 nM Poor binder