TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T69494	N-methyl-D-aspartate receptor	D02VKC	NBQX	Phase 1	3272524	C12H8N4O6S	336.28	C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B0GNJ3	Amino(2-(3-Nitrobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	44118332	C8H10ClN5O2	243.65	C1=CC(=CC(=C1)[N+](=O)[O-])/C=N/N=C(N)N.Cl	IC50 = 154881.66 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B1A2BW	Amino(2-(4-Methylbenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	49796489	C9H13ClN4	212.68	CC1=CC=C(C=C1)/C=N/N=C(N)N.Cl	IC50 = 81283.05 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B1TAS7	Amino(2-Benzylidenehydrazinyl)Methaniminium Chloride	Investigative	49796212	C8H11ClN4	198.65	C1=CC=C(C=C1)/C=N/N=C(N)N.Cl	IC50 = 72443.6 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B2TG6D	Amino(2-(3-Phenylallylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71717118	C10H13ClN4	224.69	C1=CC=C(C=C1)/C=C/C=N/N=C(N)N.Cl	IC50 = 58884.37 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B2WX8V	1-[[3-[[Carbamimidoyl(2-methylpropyl)amino]methyl]phenyl]methyl]-1-(2-methylpropyl)guanidine;dihydrochloride	Investigative	49796559	C18H34Cl2N6	405.4	CC(C)CN(CC1=CC(=CC=C1)CN(CC(C)C)C(=N)N)C(=N)N.Cl.Cl	IC50 = 112030 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B3T4OA	2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	Investigative	10658567	C8H10N6O4	254.2	CN1C(=NN=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B47EFT	1,3-Bis(4-amino-2-methylphenyl)guanidine	Investigative	14771731	C15H19N5	269.34	CC1=C(C=CC(=C1)N)NC(=NC2=C(C=C(C=C2)N)C)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B4ET2B	2-[(E)-1H-Pyrrol-2-ylmethylideneamino]guanidine;hydrochloride	Investigative	135422276	C6H10ClN5	187.63	C1=CNC(=C1)/C=N/N=C(N)N.Cl	IC50 = 95499.26 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B4H7ER	6-Chloro-4-hydroxy-3-phenyl-1H-1,8-naphthyridin-2-one	Investigative	54730148	C14H9ClN2O2	272.68	C1=CC=C(C=C1)C2=C(C3=C(NC2=O)N=CC(=C3)Cl)O	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B4U0WM	(2R)-2-Amino-3-(2H-tetrazol-5-yl)propanoic acid	Investigative	44362600	C4H7N5O2	157.13	C(C1=NNN=N1)[C@H](C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B5NY2R	(2S)-2-Amino-3-(2H-tetrazol-5-yl)propanoic acid	Investigative	3246533	C4H7N5O2	157.13	C(C1=NNN=N1)[C@@H](C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B6L0HM	Amino(2-(3-(Methoxycarbonyl)Benzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71584184	C10H13ClN4O2	256.69	COC(=O)C1=CC=CC(=C1)/C=N/N=C(N)N.Cl	IC50 = 72443.6 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B6SBC2	Amino(2-(4-(Methoxycarbonyl)Benzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71719560	C10H13ClN4O2	256.69	COC(=O)C1=CC=C(C=C1)/C=N/N=C(N)N.Cl	IC50 = 70794.58 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B6UV1Q	2-Amino-3-[5-(2-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10729534	C9H11N5O4	253.22	CN1C(=NC=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B78WRA	(1R,Alphar)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol	Investigative	9998705	C20H24ClNO3	361.9	CN1CCC2=CC(=C(C=C2[C@H]1C[C@H](C3=CC=C(C=C3)Cl)O)OC)OC	IC50 = 56000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B7C4DT	5-Acetoxy-1,4-dihydro-6,7-dimethoxyquinoxaline-2,3-dione	Investigative	11747939	C12H12N2O6	280.23	CC(=O)OC1=C2C(=CC(=C1OC)OC)NC(=O)C(=O)N2	IC50 = 53000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B7FI1S	n,n-Diphenylguanidine	Investigative	14657	C13H13N3	211.26	C1=CC=C(C=C1)N(C2=CC=CC=C2)C(=N)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B7X5YI	2-Amino-8-(2H-tetrazol-5-yl)octanoic acid;hydrochloride	Investigative	45262360	C9H18ClN5O2	263.72	C(CCCC(C(=O)O)N)CCC1=NNN=N1.Cl	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B80DEG	(1S,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol	Investigative	10783594	C20H25NO4	343.4	COC1=CC=C(C=C1)[C@@H](C[C@H]2C3=CC(=C(C=C3CCN2)OC)OC)O	IC50 = 110000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B8ERL6	2-[(E)-[5-(4-Nitrophenyl)furan-2-yl]methylideneamino]guanidine;hydrochloride	Investigative	71584311	C12H12ClN5O3	309.71	C1=CC(=CC=C1C2=CC=C(O2)/C=N/N=C(N)N)[N+](=O)[O-].Cl	IC50 = 109647.82 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B8HJ1A	5,8-Dihydro-[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione	Investigative	10845927	C9H6N2O4	206.15	C1OC2=C(O1)C=C3C(=C2)NC(=O)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B9AB0O	Amino(2-(4-Nitrobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	44118333	C8H10ClN5O2	243.65	C1=CC(=CC=C1/C=N/N=C(N)N)[N+](=O)[O-].Cl	IC50 = 77624.71 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B9L7NR	1-[[3-[[Carbamimidoyl(propyl)amino]methyl]-5-hydroxyphenyl]methyl]-1-propylguanidine;dihydrochloride	Investigative	49796550	C16H30Cl2N6O	393.4	CCCN(CC1=CC(=CC(=C1)O)CN(CCC)C(=N)N)C(=N)N.Cl.Cl	IC50 = 110500 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	B9OP3N	(2R)-2-(2-Aminoethylamino)propanoic acid	Investigative	13477634	C5H12N2O2	132.16	C[C@H](C(=O)O)NCCN	IC50 = 112000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BB2W3Z	4-Hydroxy-3-phenyl-1,5-naphthyridin-2(1H)-one	Investigative	54730140	C14H10N2O2	238.24	C1=CC=C(C=C1)C2=C(C3=C(C=CC=N3)NC2=O)O	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BB38MN	(1R,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol	Investigative	10617348	C20H25NO4	343.4	COC1=CC=C(C=C1)[C@@H](C[C@@H]2C3=CC(=C(C=C3CCN2)OC)OC)O	IC50 = 120000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BDIS47	(1R,Alphas)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol	Investigative	10666040	C21H27NO4	357.4	CN1CCC2=CC(=C(C=C2[C@H]1C[C@@H](C3=CC=C(C=C3)OC)O)OC)OC	IC50 = 120000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BDSQ52	3-Nitro-4-hydroxy-5,6,7,8-tetrafluoroquinolin-2(1H)-one	Investigative	54713079	C9H2F4N2O4	278.12	C12=C(C(=C(C(=C1F)F)F)F)NC(=O)C(=C2O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BF8A0Y	2-[(E)-(3-Hydroxy-4-methoxyphenyl)methylideneamino]guanidine;hydrochloride	Investigative	71717743	C9H13ClN4O2	244.68	COC1=C(C=C(C=C1)/C=N/N=C(N)N)O.Cl	IC50 = 63095.73 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BFG86N	2-[(E)-Thiophen-3-ylmethylideneamino]guanidine;hydrochloride	Investigative	71584446	C6H9ClN4S	204.68	C1=CSC=C1/C=N/N=C(N)N.Cl	IC50 = 181970.09 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BFWG19	4-Hydroxy-3-phenyl-1,8-naphthyridin-2(1H)-one	Investigative	54697760	C14H10N2O2	238.24	C1=CC=C(C=C1)C2=C(C3=C(NC2=O)N=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BH2PG8	Amino(2-(2,4-Difluorobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71584304	C8H9ClF2N4	234.63	C1=CC(=C(C=C1F)F)/C=N/N=C(N)N.Cl	IC50 = 54954.09 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BI5J2V	2-[3-(Diethylamino)propyl]-2-methyl-4-phenylfuran-3-one;hydrochloride	Investigative	45260674	C18H26ClNO2	323.9	CCN(CC)CCCC1(C(=O)C(=CO1)C2=CC=CC=C2)C.Cl	Ki = 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BIWK86	2-Amino-7-(2H-tetrazol-5-yl)heptanoic acid	Investigative	44362880	C8H15N5O2	213.24	C(CCC1=NNN=N1)CCC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BJ5BK1	(1S,Alphar)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol	Investigative	10497883	C19H22ClNO3	347.8	COC1=C(C=C2[C@@H](NCCC2=C1)C[C@H](C3=CC=C(C=C3)Cl)O)OC	IC50 = 95000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BK2VX9	(1R,Alphas)-1,2,3,4-Tetrahydro-6,7-dimethoxy-alpha-(4-methoxyphenyl)-1-isoquinolineethanol	Investigative	10783593	C20H25NO4	343.4	COC1=CC=C(C=C1)[C@H](C[C@@H]2C3=CC(=C(C=C3CCN2)OC)OC)O	IC50 = 140000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BKOH49	1-[[3-[[Carbamimidoyl(propyl)amino]methyl]-5-methoxyphenyl]methyl]-1-propylguanidine;dihydrochloride	Investigative	49796552	C17H32Cl2N6O	407.4	CCCN(CC1=CC(=CC(=C1)OC)CN(CCC)C(=N)N)C(=N)N.Cl.Cl	IC50 = 55260 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BM65ZG	2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	Investigative	3481675	C8H10N6O4	254.2	CN1N=C(N=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BMH0S9	2-Amino-3-[3-oxo-5-(2H-tetrazol-5-yl)-1,2-oxazol-4-yl]propanoic Acid	Investigative	10800053	C7H8N6O4	240.18	C(C1=C(ONC1=O)C2=NNN=N2)C(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BMI8G9	2-Amino-3-[3-oxo-5-(1H-1,2,4-triazol-5-yl)-1,2-oxazol-4-yl]propanoic acid	Investigative	10752476	C8H9N5O4	239.19	C1=NNC(=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BO32KM	Amino(2-(2-Fluorobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71716508	C8H10ClFN4	216.64	C1=CC=C(C(=C1)/C=N/N=C(N)N)F.Cl	IC50 = 74131.02 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BORD40	2-Amino-3-[5-(1-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10824747	C9H11N5O4	253.22	CN1C=NC(=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BP58CG	2-Amino-3-[5-(1H-imidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10823814	C9H10N4O4	238.2	C1=CN=C(N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BP98VD	3-[3-(Ethylamino)propanoylamino]propanoic acid	Investigative	25211257	C8H16N2O3	188.22	CCNCCC(=O)NCCC(=O)O	IC50 = 60000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BPN3O1	2-Amino-3-[3-oxo-5-(1,3-thiazol-2-yl)-1,2-oxazol-4-yl]propanoic Acid	Investigative	10562939	C9H9N3O4S	255.25	C1=CSC(=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BQ4RN0	3-Nitro-4-hydroxy-6,7,8-trichloroquinolin-2(1H)-one	Investigative	54704589	C9H3Cl3N2O4	309.5	C1=C2C(=C(C(=C1Cl)Cl)Cl)NC(=O)C(=C2O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BQA7D5	Amino(2-(4-Fluorobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71720158	C8H10ClFN4	216.64	C1=CC(=CC=C1/C=N/N=C(N)N)F.Cl	IC50 = 91201.08 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BS26GV	2-[(E)-1H-Indol-2-ylmethylideneamino]guanidine;hydrochloride	Investigative	136250345	C10H12ClN5	237.69	C1=CC=C2C(=C1)C=C(N2)/C=N/N=C(N)N.Cl	IC50 = 57543.99 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BSJ9M0	2-[(E)-1H-Indol-5-ylmethylideneamino]guanidine;hydrochloride	Investigative	71584314	C10H12ClN5	237.69	C1=CC2=C(C=CN2)C=C1/C=N/N=C(N)N.Cl	IC50 = 50118.72 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BU08IJ	Amino(2-(4-Aminobenzylidene)Hydrazinyl)Methaniminium Chloride	Investigative	71720799	C8H12ClN5	213.67	C1=CC(=CC=C1/C=N/N=C(N)N)N.Cl	IC50 = 109647.82 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BU27PT	2-Amino-3-[5-(1-methylimidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10610792	C10H12N4O4	252.23	CN1C=CN=C1C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BU4A6G	2-(4-Aminobutanamido)acetic acid	Investigative	12150769	C6H12N2O3	160.17	C(CC(=O)NCC(=O)O)CN	IC50 = 61000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BUL8Y4	1-[[3-[[Carbamimidoyl(ethyl)amino]methyl]phenyl]methyl]-1-ethylguanidine;dihydrochloride	Investigative	49796532	C14H26Cl2N6	349.3	CCN(CC1=CC(=CC=C1)CN(CC)C(=N)N)C(=N)N.Cl.Cl	IC50 = 75800 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BUP3Q8	3-Nitro-4-hydroxy-5-chloroquinolin-2(1H)-one	Investigative	54708009	C9H5ClN2O4	240.6	C1=CC2=C(C(=C1)Cl)C(=C(C(=O)N2)[N+](=O)[O-])O	IC50 = 61000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BWE27G	2(1H)-Quinolinone, 6-chloro-4-hydroxy-3-nitro-	Investigative	54705784	C9H5ClN2O4	240.6	C1=CC2=C(C=C1Cl)C(=C(C(=O)N2)[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BWG6E3	1-[[6-[[Carbamimidoyl(propyl)amino]methyl]pyridin-2-yl]methyl]-1-propylguanidine;dihydrochloride	Investigative	49796535	C15H29Cl2N7	378.3	CCCN(CC1=NC(=CC=C1)CN(CCC)C(=N)N)C(=N)N.Cl.Cl	IC50 = 95210 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BY27DB	8-Chloroquinoline-2,3,4(1H)-trione 3-oxime	Investigative	135522010	C9H5ClN2O3	224.6	C1=CC2=C(C(=C1)Cl)NC(=O)C(=C2O)N=O	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BY36CF	(1S,Alphar)-1,2,3,4-Tetrahydro-2-methyl-6,7-dimethoxy-alpha-(4-chlorophenyl)-1-isoquinolineethanol	Investigative	10546555	C20H24ClNO3	361.9	CN1CCC2=CC(=C(C=C2[C@@H]1C[C@H](C3=CC=C(C=C3)Cl)O)OC)OC	IC50 = 52000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BYO8S0	8-Chloro-4-hydroxy-3-nitroquinolin-2(1H)-one	Investigative	54696453	C9H5ClN2O4	240.6	C1=CC2=C(C(=C1)Cl)NC(=O)C(=C2O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	BZDK59	2,3-Quinoxalinedione, 1,4-dihydro-6,7-dihydroxy-	Investigative	10774166	C8H6N2O4	194.14	C1=C2C(=CC(=C1O)O)NC(=O)C(=O)N2	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	D03RGP	(R,S)-AMPA	Investigative	1221	C7H10N2O4	186.17	CC1=C(C(=O)NO1)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T69494	N-methyl-D-aspartate receptor	D0S6HI	arcaine	Investigative	2227	C6H16N6	172.23	C(CCN=C(N)N)CN=C(N)N	IC50 = 79980 nM	Poor binder