TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	B0SY5C	(1R,2S)-2-[(1R)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylic acid	Investigative	40482358	C26H26N2O5	446.5	C1CC[C@H]([C@H](C1)C(=O)N2CCC3=CC=CC=C3[C@@H]2CN4C(=O)C5=CC=CC=C5C4=O)C(=O)O	EC50 ~ 100000 nM	Poor binder
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	B3M4QT	Chembl4176009	Investigative	145974303	C24H27NO3	377.5	C1CC[C@@H]([C@@H](C1)C(=O)N2CCC3=CC=CC=C3[C@H]2CC4=CC=CC=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	B46YPN	Chembl4165400	Investigative	145955145	C25H25N3O5	447.5	C1C[C@H]([C@H](NC1)C(=O)O)C(=O)N2CCC3=CC=CC=C3[C@H]2CN4C(=O)C5=CC=CC=C5C4=O	IC50 = 69700 nM	Poor binder
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	B6E4NJ	2-({5-[(2,4-Dimethylphenyl)sulfonyl]-6-Oxo-1,6-Dihydropyrimidin-2-Yl}sulfanyl)-N-[2-(Trifluoromethyl)phenyl]acetamide	Investigative	50744391	C21H18F3N3O4S2	497.5	CC1=CC(=C(C=C1)S(=O)(=O)C2=CN=C(NC2=O)SCC(=O)NC3=CC=CC=C3C(F)(F)F)C	EC50 = 118000 nM	Poor binder
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	B7CM2I	2-[[(1S)-2-(Cyclohexanecarbonyl)-3,4-dihydro-1H-isoquinolin-1-yl]methyl]isoindole-1,3-dione	Investigative	1070170	C25H26N2O3	402.5	C1CCC(CC1)C(=O)N2CCC3=CC=CC=C3[C@H]2CN4C(=O)C5=CC=CC=C5C4=O	IC50 ~ 100000 nM	Poor binder
T72491	Keap1-Nrf2[dual DLG and ETGE] PPI	BG2U5P	(1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylic acid	Investigative	3307826	C26H26N2O5	446.5	C1CCC(C(C1)C(=O)N2CCC3=CC=CC=C3C2CN4C(=O)C5=CC=CC=C5C4=O)C(=O)O	EC50 ~ 100000 nM	Poor binder