TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74977	Dual specificity protein kinase TTK	D0R6TI	Inamrinone Lactate	Approved	3698	C10H9N3O	187.2	C1=CN=CC=C1C2=CNC(=O)C(=C2)N	Ki = 80800 nM	Poor binder
T74977	Dual specificity protein kinase TTK	D0Y9ZE	Milrinone	Approved	4197	C12H9N3O	211.22	CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	B3HWU9	2-Methoxy-5-(pyridine-4-yl)pyridine-3-amine	Investigative	13942472	C11H11N3O	201.22	COC1=C(C=C(C=N1)C2=CC=NC=C2)N	Ki = 91200 nM	Poor binder
T74977	Dual specificity protein kinase TTK	B4ZNV6	5-Amino-[3,3'-bipyridin]-6(1H)-one	Investigative	119131	C10H9N3O	187.2	C1=CC(=CN=C1)C2=CNC(=O)C(=C2)N	Ki = 98100 nM	Poor binder
T74977	Dual specificity protein kinase TTK	B7V4ZP	3-Amino-5-(1-Methyl-1h-Pyrazol-4-Yl)pyridin-2(1h)-One	Investigative	91667406	C9H10N4O	190.2	CN1C=C(C=N1)C2=CNC(=O)C(=C2)N	Ki = 94700 nM	Poor binder
T74977	Dual specificity protein kinase TTK	B8F0PB	[3,4'-Bipyridin]-6(1H)-one, 5-amino-2-methyl-	Investigative	12799333	C11H11N3O	201.22	CC1=C(C=C(C(=O)N1)N)C2=CC=NC=C2	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BA2M7D	N-(6-Oxo-1,6-dihydro-[3,4']bipyridinyl-5-yl)-benzenesulfonamide	Investigative	58692572	C16H13N3O3S	327.4	C1=CC=C(C=C1)S(=O)(=O)NC2=CC(=CNC2=O)C3=CC=NC=C3	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BN0I2H	Chembl4281678	Investigative	110868446	C17H12FN3O2	309.29	C1=CC(=CC(=C1)F)C(=O)NC2=CC(=CNC2=O)C3=CC=NC=C3	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BUR10Z	3-(2,6-Diethylphenyl)-1-methyl-1-[3-(3-sulfamoylphenyl)-1H-indazol-5-yl]urea	Investigative	118712916	C25H27N5O3S	477.6	CCC1=C(C(=CC=C1)CC)NC(=O)N(C)C2=CC3=C(C=C2)NN=C3C4=CC(=CC=C4)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BV81NR	2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxamide	Investigative	12799331	C12H11N3O2	229.23	CC1=C(C=C(C(=O)N1)C(=O)N)C2=CC=NC=C2	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BW6VA0	Chembl4279867	Investigative	11631251	C17H11F2N3O2	327.28	C1=CN=CC=C1C2=CNC(=O)C(=C2)NC(=O)C3=CC(=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BYK32Z	[3-(4-Chloro-1H-indazol-3-yl)phenyl]methanamine	Investigative	118712908	C14H12ClN3	257.72	C1=CC(=CC(=C1)C2=NNC3=C2C(=CC=C3)Cl)CN	IC50 ~ 50000 nM	Poor binder
T74977	Dual specificity protein kinase TTK	BYT6L9	3-Amino-5-phenyl-1H-pyridin-2-one	Investigative	25181368	C11H10N2O	186.21	C1=CC=C(C=C1)C2=CNC(=O)C(=C2)N	Ki = 128200 nM	Poor binder