TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T75243	Serine/threonine-protein kinase mTOR	D0W5HK	Sorafenib	Approved	216239	C21H16ClF3N4O3	464.8	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	D01RYO	Gefitinib	Patented	123631	C22H24ClFN4O3	446.9	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	D0YX2B	PMID28460551-Compound-2	Patented	5329102	C22H27FN4O2	398.5	CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)F)NC2=O)C	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B0R8UT	Imidazo[1,2-a]pyridine, 3-(5,6-dimethoxy-3-pyridinyl)-	Investigative	46913419	C14H13N3O2	255.27	COC1=C(N=CC(=C1)C2=CN=C3N2C=CC=C3)OC	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B0RX4G	1-Tert-butyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905330	C17H21N5O2	327.4	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)OC)OC)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B1WJT8	Tert-Butyl {4-[4-Amino-1-(Propan-2-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-3-Yl]-2-Methoxyphenyl}carbamate	Investigative	24905150	C20H26N6O3	398.5	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)NC(=O)OC(C)(C)C)OC)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B2EW8I	3-(Phenylethynyl)-1H-indazole	Investigative	20644743	C15H10N2	218.25	C1=CC=C(C=C1)C#CC2=C3C=CC=CC3=NN2	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B2K4CJ	N-(3-(9H-Purin-6-yl)pyridin-2-yl)-1H-indol-4-amine	Investigative	59548183	C18H13N7	327.3	C1=CC2=C(C=CN2)C(=C1)NC3=C(C=CC=N3)C4=C5C(=NC=N4)N=CN5	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B2U0DS	N-[3-(6-Amino-2-methylpyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine	Investigative	59548454	C17H15N7	317.3	CC1=NC(=CC(=N1)N)C2=C(N=CC=C2)NC3=CC=CC4=C3C=NN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B2UXL3	N-(3-(4-Amino-6-methyl-1,3,5-triazin-2-YL)-5-methylpyridine-2-YL)-1H-indazol-4-amine	Investigative	49786007	C17H16N8	332.4	CC1=CC(=C(N=C1)NC2=CC=CC3=C2C=NN3)C4=NC(=NC(=N4)C)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B3CU2L	3-(2-Ethoxynaphthalen-6-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905207	C18H17N5O	319.4	CCOC1=CC2=C(C=C1)C=C(C=C2)C3=NN(C4=NC=NC(=C34)N)C	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B3Q7NC	3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hindazole	Investigative	42606083	C17H8F6N2	354.25	C1=CC2=C(NN=C2C=C1)C#CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B47KSW	N-(3-(6-Amino-2-methylpyrimidin-4-yl)pyridin-4-yl)-1H-indazol-4-amine	Investigative	59548455	C17H15N7	317.3	CC1=NC(=CC(=N1)N)C2=C(C=CN=C2)NC3=CC=CC4=C3C=NN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B4HX3I	1-Isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905171	C12H13N7	255.28	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CN=CN=C3)N	IC50 = 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B5O3DA	3-(4-Amino-3-methoxyphenyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905251	C15H18N6O	298.34	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)N)OC)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B5PHQ9	8-[(8-Fluoro-2,3-dihydro-1,4-benzoxazin-4-yl)methyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide	Investigative	127046317	C25H26FN3O5	467.5	CN(C)C(=O)C1=CC(=C2C(=C1)C(=O)C=C(O2)N3CCOCC3)CN4CCOC5=C4C=CC=C5F	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B61VGT	3-((3,5-Difluorophenyl)ethynyl)-1H-indazole	Investigative	42606079	C15H8F2N2	254.23	C1=CC2=C(NN=C2C=C1)C#CC3=CC(=CC(=C3)F)F	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B6A0VO	5-(4-Amino-1-((5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenol	Investigative	24905307	C21H17FN8O	416.4	CC1=NN(N=C1CN2C3=NC=NC(=C3C(=N2)C4=CC(=C(C=C4)F)O)N)C5=CC=CC=C5	IC50 = 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B6JS7B	4-((1H-Indazol-3-yl)ethynyl)benzonitrile	Investigative	42606194	C16H9N3	243.26	C1=CC2=C(NN=C2C=C1)C#CC3=CC=C(C=C3)C#N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B7ILR1	2-[4-Amino-3-(3-ethoxy-4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethanol	Investigative	52940797	C16H19N5O3	329.35	CCOC1=C(C=CC(=C1)C2=NN(C3=NC=NC(=C23)N)CCO)OC	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B7KTG1	2-[4-({4-[4-Methyl-3-(methylsulfamoyl)phenyl]phthalazin-1-yl}amino)phenoxy]acetamide	Investigative	1420707	C24H23N5O4S	477.5	CC1=C(C=C(C=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OCC(=O)N)S(=O)(=O)NC	IC50 = 52200 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B7OK8F	4-Methyl-6-[5-methyl-2-(pyridin-3-ylamino)pyridin-3-yl]-1,3,5-triazin-2-amine	Investigative	49785254	C15H15N7	293.33	CC1=CC(=C(N=C1)NC2=CN=CC=C2)C3=NC(=NC(=N3)C)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B7Z0UL	N-[5-[(4-Methoxyphenyl)methoxymethyl]-3-(2-methyl-7H-purin-6-yl)pyridin-2-yl]-1H-indol-4-amine	Investigative	49785170	C28H25N7O2	491.5	CC1=NC(=C2C(=N1)N=CN2)C3=C(N=CC(=C3)COCC4=CC=C(C=C4)OC)NC5=CC=CC6=C5C=CN6	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B8AW2L	1-Isopropyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905177	C17H21N5O3	343.4	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C(=C3)OC)OC)OC)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B8IBH3	N-(3-(4-Amino-6-methyl-1,3,5-triazin-2-YL)pyridin-2-YL)-1H-indazol-4-amine	Investigative	49784893	C16H14N8	318.34	CC1=NC(=NC(=N1)N)C2=C(N=CC=C2)NC3=CC=CC4=C3C=NN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B8U2WB	N-(3-(6-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-2-yl)-1H-indazol-4-amine	Investigative	49785829	C18H14N8	342.4	CC1=NC(=C2C=NNC2=N1)C3=C(N=CC=C3)NC4=CC=CC5=C4C=NN5	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	B92JEA	1-(4-Amino-6-methyl-1,3,5-triazin-2-yl)-N-(2-methylpyrazol-3-yl)benzimidazol-2-amine	Investigative	54584860	C15H15N9	321.34	CC1=NC(=NC(=N1)N2C3=CC=CC=C3N=C2NC4=CC=NN4C)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BA59TB	3-(Thiophen-3-ylethynyl)-1H-indazole	Investigative	42606190	C13H8N2S	224.28	C1=CC2=C(NN=C2C=C1)C#CC3=CSC=C3	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BAI94H	N-[3-[6-Amino-2-(trifluoromethyl)pyrimidin-4-yl]pyridin-2-yl]-1H-indazol-4-amine	Investigative	59548480	C17H12F3N7	371.3	C1=CC2=C(C=NN2)C(=C1)NC3=C(C=CC=N3)C4=CC(=NC(=N4)C(F)(F)F)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BB2S4A	2-((4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one	Investigative	24905149	C28H23N7O2	489.5	CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C(=N4)C6=CC(=CC=C6)O)N	IC50 = 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BB6J1Q	1-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)ethanone	Investigative	24905155	C16H17N5O	295.34	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)C(=O)C)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BB8J4R	3-(Benzo[c][1,2,5]oxadiazol-6-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905165	C14H13N7O	295.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=NON=C4C=C3)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BBV8D1	4-[2-[(6-Methoxypyridin-3-yl)amino]-5-methylpyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine	Investigative	59548226	C16H17N7O	323.35	CC1=CC(=C(N=C1)NC2=CN=C(C=C2)OC)C3=NC(=NC(=N3)C)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BBWU45	6-(4-Amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905227	C19H18N6O	346.4	C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)NC(=O)C=C5)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BCA19X	N-(3-(6-Amino-2-methylpyrimidin-4-yl)pyridin-4-yl)-1H-indol-4-amine	Investigative	49784797	C18H16N6	316.4	CC1=NC(=CC(=N1)N)C2=C(C=CN=C2)NC3=CC=CC4=C3C=CN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BCRL26	4-[2-(1-Methylindol-5-yl)-6-(methylsulfonylmethyl)pyrimidin-4-yl]morpholine	Investigative	70694178	C19H22N4O3S	386.5	CN1C=CC2=C1C=CC(=C2)C3=NC(=CC(=N3)N4CCOCC4)CS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BD8H0B	7-(2-Furylmethyl)-N-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	2930286	C29H26N6O	474.6	C1=CC=C(C=C1)C2=C(N(C3=NC=NC(=C23)NCCCN4C=CN=C4)CC5=CC=CO5)C6=CC=CC=C6	IC50 = 54100 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BDF6E7	N-[3-(6-Amino-5-fluoro-2-methylpyrimidin-4-yl)pyridin-2-yl]-1H-indazol-4-amine	Investigative	49785167	C17H14FN7	335.3	CC1=NC(=C(C(=N1)N)F)C2=C(N=CC=C2)NC3=CC=CC4=C3C=NN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BDZR13	4-[4-[6-Chloro-4-(trifluoromethyl)pyridin-3-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine	Investigative	137662160	C17H18ClF3N6O2	430.8	C1COCCN1C2=NC(=NC(=N2)C3=CN=C(C=C3C(F)(F)F)Cl)N4CCOCC4	Ki = 110000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BFC05S	3-(Pyridin-3-ylethynyl)-1h-indazole	Investigative	42606080	C14H9N3	219.24	C1=CC2=C(NN=C2C=C1)C#CC3=CN=CC=C3	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BGEP17	3-[3-(Dimethylamino)-1-propynyl]-1H-indazole	Investigative	49852123	C12H13N3	199.25	CN(C)CC#CC1=C2C=CC=CC2=NN1	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BGZ6D3	N-(2-Chloro-5-imidazo[1,2-a]pyrimidin-3-ylpyridin-3-yl)-4-fluorobenzenesulfonamide	Investigative	46913619	C17H11ClFN5O2S	403.8	C1=CN2C(=CN=C2N=C1)C3=CC(=C(N=C3)Cl)NS(=O)(=O)C4=CC=C(C=C4)F	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BH1FA3	6-(4-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-4H-chromen-4-one	Investigative	24905234	C15H11N5O2	293.28	CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC=CC4=O)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BJR40B	5-(4-Amino-1-((piperidin-4-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenol	Investigative	24905301	C17H19FN6O	342.4	C1CNCCC1CN2C3=NC=NC(=C3C(=N2)C4=CC(=C(C=C4)F)O)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BLWV61	N-(6-(4-(1H-Indol-4-ylamino)pyridin-3-yl)-2-methylpyrimidin-4-yl)acetamide	Investigative	49784796	C20H18N6O	358.4	CC1=NC(=CC(=N1)NC(=O)C)C2=C(C=CN=C2)NC3=CC=CC4=C3C=CN4	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BM12SC	3-(1-(4-(2,2,2-Trifluoroethylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol	Investigative	54582056	C18H14F3N7O	401.3	C1=CC=C2C(=C1)N=C(N2C3=NC=NC(=N3)NCC(F)(F)F)NC4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BMQ0D2	2-(4-(2-(3-Hydroxyphenylamino)-1H-benzo[d]imidazol-1-yl)-6-methoxy-1,3,5-triazin-2-ylamino)acetonitrile	Investigative	54580063	C19H16N8O2	388.4	COC1=NC(=NC(=N1)N2C3=CC=CC=C3N=C2NC4=CC(=CC=C4)O)NCC#N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BN1U3V	4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorobenzonitrile	Investigative	24905237	C15H13FN6	296.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)C#N)F)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BNMX13	2-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	21048651	C15H11N3	233.27	C1=CC=C(C(=C1)C#CC2=C3C=CC=CC3=NN2)N	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BO40RN	3-(Pyridin-2-ylethynyl)-1H-indazole	Investigative	42606191	C14H9N3	219.24	C1=CC=NC(=C1)C#CC2=C3C=CC=CC3=NN2	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BOA45D	3-(4-Ethoxy-3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905292	C14H15N5O2	285.3	CCOC1=C(C=C(C=C1)C2=C3C(=NC=NC3=NN2)N)OC	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BQTP35	3-(Cyclopropylethynyl)-1H-indazole	Investigative	42606195	C12H10N2	182.22	C1CC1C#CC2=C3C=CC=CC3=NN2	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BRD29U	N-[3-(7H-Purin-6-yl)pyridin-2-yl]-1H-indazol-4-amine	Investigative	59548207	C17H12N8	328.3	C1=CC2=C(C=NN2)C(=C1)NC3=C(C=CC=N3)C4=C5C(=NC=N4)N=CN5	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BT5H2Q	3-(Cyclopentylethynyl)-1H-indazole	Investigative	42606196	C14H14N2	210.27	C1CCC(C1)C#CC2=C3C=CC=CC3=NN2	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BUZ06A	5-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorobenzonitrile	Investigative	24905236	C15H13FN6	296.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)F)C#N)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BWQN23	3-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	42606076	C15H11N3	233.27	C1=CC2=C(NN=C2C=C1)C#CC3=CC(=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BX64LT	1-Methyl-3-Naphthalen-2-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine	Investigative	24905144	C16H13N5	275.31	CN1C2=NC=NC(=C2C(=N1)C3=CC4=CC=CC=C4C=C3)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BXEU15	3-(1-(4-Methoxy-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol	Investigative	54584986	C17H14N6O2	334.33	COC1=NC=NC(=N1)N2C3=CC=CC=C3N=C2NC4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BXM9I2	3-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide	Investigative	1882360	C30H27N3O3S	509.6	COC1=C(C=C(C=C1)CCNC(=O)C2=C(C3=C(S2)N=C(C=C3C4=CC=CC=C4)C5=CC=CC=C5)N)OC	IC50 = 57600 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	BXW73J	5-(4-Amino-1-((4-phenyloxazol-5-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenol	Investigative	24905308	C21H15FN6O2	402.4	C1=CC=C(C=C1)C2=C(OC=N2)CN3C4=NC=NC(=C4C(=N3)C5=CC(=C(C=C5)F)O)N	IC50 = 100000 nM	Poor binder
T75243	Serine/threonine-protein kinase mTOR	D03QQH	AMA37	Investigative	16760391	C17H17NO3	283.32	C1COCCN1C2=CC(=C(C=C2)C(=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder