TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T76369	Liver carboxylesterase	D0E6YQ	Tacrine	Approved	1935	C13H14N2	198.26	C1CCC2=NC3=CC=CC=C3C(=C2C1)N	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0NS6H	Donepezil	Approved	3152	C24H29NO3	379.5	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B04PHN	6-(3-(7-Phenylheptanoyl)-1,2,4-oxadiazol-5-yl)-picolinic Acid	Investigative	24950363	C21H21N3O4	379.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NOC(=N2)C3=NC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B0MR7F	4,7-Dimethyl-1H-indole-2,3-dione	Investigative	3264931	C10H9NO2	175.18	CC1=C2C(=C(C=C1)C)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B0P1WZ	7-Methoxyindoline-2,3-dione	Investigative	4088910	C9H7NO3	177.16	COC1=CC=CC2=C1NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B0Q1ZX	Dibenzyl sulfoxide	Investigative	12116	C14H14OS	230.33	C1=CC=C(C=C1)CS(=O)CC2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B0SOM1	1,2-Bis(4-ethoxyphenyl)ethane-1,2-dione	Investigative	4369935	C18H18O4	298.3	CCOC1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)OCC	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B1A9NI	N,N''-(1,4-Phenylene)bis(4-fluoro-2-methylbenzene sulfonamide)	Investigative	44583159	C20H18F2N2O4S2	452.5	CC1=CC(=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=C(C=C(C=C3)C)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B1BGJ4	N,N''-(2,5-Dichloro-1,4-phenylene)bis(4-chlorobenzene sulfonamide)	Investigative	1167776	C18H12Cl4N2O4S2	526.2	C1=CC(=CC=C1S(=O)(=O)NC2=CC(=C(C=C2Cl)NS(=O)(=O)C3=CC=C(C=C3)Cl)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B1EGP3	{2,5-Dibromo-4-[(phenylsulfonyl)amino]phenyl}(phenylsulfonyl)amine	Investigative	1133380	C18H14Br2N2O4S2	546.3	C1=CC=C(C=C1)S(=O)(=O)NC2=CC(=C(C=C2Br)NS(=O)(=O)C3=CC=CC=C3)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B1JF0A	1,2-Bis[3-(trifluoromethyl)phenyl]ethane-1,2-dione	Investigative	22574246	C16H8F6O2	346.22	C1=CC(=CC(=C1)C(F)(F)F)C(=O)C(=O)C2=CC(=CC=C2)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B1MOR9	3,4,5-Trifluoro-N-[7-[(3,4,5-trifluorophenyl)sulfonylamino]-9H-fluoren-2-yl]benzenesulfonamide	Investigative	44157442	C25H14F6N2O4S2	584.5	C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC(=C(C(=C3)F)F)F)C4=C1C=C(C=C4)NS(=O)(=O)C5=CC(=C(C(=C5)F)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B24OCQ	1-(Hydroxymethyl)indole-2,3-dione	Investigative	39834	C9H7NO3	177.16	C1=CC=C2C(=C1)C(=O)C(=O)N2CO	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B26ZHX	Sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate	Investigative	23669322	C19H17NaO6S	396.4	CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B32JLI	N-[4-(Benzenesulfonamido)-3-chlorophenyl]benzenesulfonamide	Investigative	232004	C18H15ClN2O4S2	422.9	C1=CC=C(C=C1)S(=O)(=O)NC2=CC(=C(C=C2)NS(=O)(=O)C3=CC=CC=C3)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B34EDJ	N-(7-(Phenylsulfonamido)-9H-fluoren-2-yl)benzenesulfurous acid	Investigative	44157441	C25H20N2O4S2	476.6	C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3)C4=C1C=C(C=C4)NS(=O)(=O)C5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3BUW1	Chembl4174080	Investigative	145951659	C32H42O4	490.7	CCCCCCCCC(=O)C1=C2C=C(OC2=CC=C1)C3=C(C=CC=C3O)C(=O)CCCCCCCC	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3D1OX	4-Fluoro-N-[2,3,5,6-tetrafluoro-4-[(4-fluorophenyl)sulfonylamino]phenyl]benzenesulfonamide	Investigative	44157439	C18H10F6N2O4S2	496.4	C1=CC(=CC=C1F)S(=O)(=O)NC2=C(C(=C(C(=C2F)F)NS(=O)(=O)C3=CC=C(C=C3)F)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3JUX2	Diphenyl oxalate	Investigative	18475	C14H10O4	242.23	C1=CC=C(C=C1)OC(=O)C(=O)OC2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3LM2P	2-(4-Dimethylaminophenyl)-2-hydroxy-1-phenylethanone	Investigative	590628	C16H17NO2	255.31	CN(C)C1=CC=C(C=C1)C(C(=O)C2=CC=CC=C2)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3NPW2	4-[[(3S,4Ar,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-ethoxycarbonyl-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-4-oxobutanoic acid	Investigative	56931986	C36H54O7	598.8	CCOC(=O)[C@]1(CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OC(=O)CCC(=O)O)C)C)[C@@H]2C1)C)C)C	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3O5PJ	6-[2-(7-Phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid	Investigative	16110715	C22H22N2O4	378.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=NC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3U9JO	5,6-Dimethylmorpholine-2,3-dione	Investigative	3469206	C6H9NO3	143.14	CC1C(OC(=O)C(=O)N1)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3Z8GN	3,5,5-Trimethylcyclohexane-1,2-dione	Investigative	93772	C9H14O2	154.21	CC1CC(CC(=O)C1=O)(C)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B3Z9CR	2-Methyl-1,3-cyclopentanedione	Investigative	13005	C6H8O2	112.13	CC1C(=O)CCC1=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B43RBQ	7-Phenyl-1-(6-(pyridin-2-yl)-pyridazin-3-yl)-heptan-1-one	Investigative	24951320	C22H23N3O	345.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NN=C(C=C2)C3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B4H8SQ	[(3S,4Ar,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-cyano-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl] acetate	Investigative	127030256	C32H47NO3	493.7	CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@@]3([C@@H]2C(=O)C=C4[C@]3(CC[C@@]5([C@H]4C[C@@](CC5)(C)C#N)C)C)C)C	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B4PAY9	(4-{[(2,5-Difluorophenyl)sulfonyl]amino}phenyl)[(4-methylphenyl)sulfonyl]amine	Investigative	22772980	C19H16F2N2O4S2	438.5	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=C(C=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B52NTV	4-Chloro-N-(4-{[(4-methylphenyl)sulfonyl]amino}phenyl)benzenesulfonamide	Investigative	5080545	C19H17ClN2O4S2	436.9	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B54MVH	2,2',4,4'-Tetrahydroxybenzil	Investigative	219592	C14H10O6	274.22	C1=CC(=C(C=C1O)O)C(=O)C(=O)C2=C(C=C(C=C2)O)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B59DWN	Paecilocin A	Investigative	53483972	C16H22O3	262.34	CCCCCCCC[C@H]1C2=C(C(=CC=C2)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B5EK0W	[(4-Bromophenyl)sulfonyl](4-{[(4-bromophenyl)sulfonyl]amino}phenyl)amine	Investigative	5235003	C18H14Br2N2O4S2	546.3	C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)Br)NS(=O)(=O)C3=CC=C(C=C3)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B5GU8F	6-Ethyl-1H-indole-2,3-dione	Investigative	13827083	C10H9NO2	175.18	CCC1=CC2=C(C=C1)C(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B5MNU6	N,N'-Benzene-1,4-diylbis(2,5-dichlorobenzenesulfonamide)	Investigative	4118889	C18H12Cl4N2O4S2	526.2	C1=CC(=CC=C1NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)NS(=O)(=O)C3=C(C=CC(=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B5TI6J	Methyl 6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinate	Investigative	24950528	C24H25N3O3	403.5	COC(=O)C1=CC=CC(=N1)C2=NN=C(C=C2)C(=O)CCCCCCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B5ZRM1	N,N''-(9H-Fluorene-2,7-diyl)bis(4-chlorobenzenesulfonamide)	Investigative	44157513	C25H18Cl2N2O4S2	545.5	C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)Cl)C4=C1C=C(C=C4)NS(=O)(=O)C5=CC=C(C=C5)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B60ZIQ	3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzoic acid	Investigative	16110699	C23H23NO4	377.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B6ATU2	2-(4-Methoxyphenyl)-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)phenyl)acetamide	Investigative	49858100	C22H18N2O4	374.4	COC1=CC=C(C=C1)CC(=O)NC2=CC=CC(=C2)C(=O)C(=O)C3=CC=CC=N3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B6R3ZY	4-{[4-(4-Fluorobenzenesulfonamido)phenyl]sulfamoyl}-N-methylbenzamide	Investigative	25325634	C20H18FN3O5S2	463.5	CNC(=O)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B74POD	3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzamide	Investigative	16110641	C23H24N2O3	376.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=CC(=CC=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B7APW0	6-[2-(3-Biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid	Investigative	24799115	C24H18N2O4	398.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(=O)C3=NC=C(O3)C4=NC(=CC=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B7ENU5	4-Chloro-N-[4-[(4-chlorophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157371	C22H22Cl2N2O4S2	513.5	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC=C(C=C2)Cl)C)C)NS(=O)(=O)C3=CC=C(C=C3)Cl)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B7J3FI	3-Methylcyclohexane-1,2-dione	Investigative	3321360	C7H10O2	126.15	CC1CCCC(=O)C1=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B8AKN4	Benzophenone	Investigative	3102	C13H10O	182.22	C1=CC=C(C=C1)C(=O)C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B8GHW4	3-(N-(4-(4-Fluorophenylsulfonamido)phenyl)sulfamoyl)-4-methyl benzoic acid	Investigative	22109309	C20H17FN2O6S2	464.5	CC1=C(C=C(C=C1)C(=O)O)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B8OPY9	1,2-Bis[3,5-bis(trifluoromethyl)phenyl]-ethane-1,2-dione	Investigative	44428843	C18H6F12O2	482.2	C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C(=O)C(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B8V2YR	(1S)-(+)-Camphorquinone	Investigative	12222796	C10H14O2	166.22	C[C@]12CC[C@@H](C1(C)C)C(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B8YQ9D	2-Methylcyclohexane-1,3-dione	Investigative	70945	C7H10O2	126.15	CC1C(=O)CCCC1=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B9AEQ2	N,N''-(9H-Fluorene-2,7-diyl)bis(3-chlorobenzenesulfonamide)	Investigative	44157512	C25H18Cl2N2O4S2	545.5	C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC(=CC=C3)Cl)C4=C1C=C(C=C4)NS(=O)(=O)C5=CC(=CC=C5)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B9TF3C	N,N''-(1,4-Phenylene)bis(3,4,5-trifluorobenzene sulfonamide)	Investigative	44157294	C18H10F6N2O4S2	496.4	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=C(C(=C2)F)F)F)NS(=O)(=O)C3=CC(=C(C(=C3)F)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	B9TJ8V	1-Thiomorpholin-4-ylmethyl-1H-indole-2,3-dione	Investigative	3531512	C13H14N2O2S	262.33	C1CSCCN1CN2C3=CC=CC=C3C(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BA0D9H	3-Oxoglycyrrhetinic acid	Investigative	111253	C30H44O4	468.7	C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CCC(=O)C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)C)(C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BA2ZQ3	N,N''-(2,5-Dibromo-1,4-phenylene)bis(4-chlorobenzene sulfonamide	Investigative	2835143	C18H12Br2Cl2N2O4S2	615.1	C1=CC(=CC=C1S(=O)(=O)NC2=CC(=C(C=C2Br)NS(=O)(=O)C3=CC=C(C=C3)Cl)Br)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BA30IV	3-Bromo-N-[4-[(3-bromophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157372	C22H22Br2N2O4S2	602.4	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC(=CC=C2)Br)C)C)NS(=O)(=O)C3=CC(=CC=C3)Br)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BA8FT5	1-(2-Chloroacetyl)indole-2,3-dione	Investigative	4350924	C10H6ClNO3	223.61	C1=CC=C2C(=C1)C(=O)C(=O)N2C(=O)CCl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BAI8S6	1,2-Bis[2,4-bis(trifluoromethyl)phenyl]ethane-1,2-dione	Investigative	44428842	C18H6F12O2	482.2	C1=CC(=C(C=C1C(F)(F)F)C(F)(F)F)C(=O)C(=O)C2=C(C=C(C=C2)C(F)(F)F)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BAM80F	1,3-Cyclohexanedione	Investigative	10434	C6H8O2	112.13	C1CC(=O)CC(=O)C1	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BBC15I	4-Bromo-N-[4-[(4-bromophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157373	C22H22Br2N2O4S2	602.4	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC=C(C=C2)Br)C)C)NS(=O)(=O)C3=CC=C(C=C3)Br)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BC3UX6	(4-{[(3,4-Difluorophenyl)sulfonyl]amino}phenyl)[(4-methylphenyl)sulfonyl]amine	Investigative	22772981	C19H16F2N2O4S2	438.5	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC(=C(C=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BC5RN3	6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinic Acid	Investigative	24948911	C23H23N3O3	389.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NN=C(C=C2)C3=NC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BD0CK7	2-Hydroxy-1,2-bis(4-methoxyphenyl)ethanone	Investigative	95415	C16H16O4	272.29	COC1=CC=C(C=C1)C(C(=O)C2=CC=C(C=C2)OC)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BD93TU	4-Chloro-N-(4-ethoxyphenyl)benzenesulfonamide	Investigative	306215	C14H14ClNO3S	311.8	CCOC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BDL2H3	N,N''-(1,4-Phenylene)bis(2,6-difluoro benzene sulfonamide)	Investigative	44157220	C18H12F4N2O4S2	460.4	C1=CC(=C(C(=C1)F)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=C(C=CC=C3F)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BE7J6F	N-(4-(4-Fluorophenylsulfonamido)phenyl)-2,5-dimethylbenzene sulfonamide	Investigative	17485200	C20H19FN2O4S2	434.5	CC1=CC(=C(C=C1)C)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BEQ7W0	3,4-Difluoro-N-(4-(phenylsulfonamido)phenyl)benzene sulfonamide	Investigative	17479504	C18H14F2N2O4S2	424.4	C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC(=C(C=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BEX15Z	2-(2,3-Dioxo-2,3-dihydro-1H-indol-1-yl)-N-(4-hydroxyphenyl)acetamide	Investigative	3329233	C16H12N2O4	296.28	C1=CC=C2C(=C1)C(=O)C(=O)N2CC(=O)NC3=CC=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BG3XB8	S1,S2-Diphenyl Ethane Bis Thioate	Investigative	18471933	C14H10O2S2	274.4	C1=CC=C(C=C1)SC(=O)C(=O)SC2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BG5U7D	5-Methoxyisatin	Investigative	38333	C9H7NO3	177.16	COC1=CC2=C(C=C1)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BGQ53W	1,2-Cyclohexanedione	Investigative	13006	C6H8O2	112.13	C1CCC(=O)C(=O)C1	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BH2G7T	4-Bromo-N-(4-phenoxyphenyl)benzenesulfonamide	Investigative	4381638	C18H14BrNO3S	404.3	C1=CC=C(C=C1)OC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BH59AK	N-[4-(4-Fluorobenzenesulfonamido)phenyl]-4-methoxybenzene-1-sulfonamide	Investigative	16324698	C19H17FN2O5S2	436.5	COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BHEJ40	N,N''-(1,4-Phenylene)bis(3,4-dichlorobenzene sulfonamide)	Investigative	44157296	C18H12Cl4N2O4S2	526.2	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=C(C=C2)Cl)Cl)NS(=O)(=O)C3=CC(=C(C=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BHL42N	1-[(Naphthalen-2-ylamino)methyl]-2,3-dihydro-1H-indole-2,3-dione	Investigative	2731126	C19H14N2O2	302.3	C1=CC=C2C=C(C=CC2=C1)NCN3C4=CC=CC=C4C(=O)C3=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BI1JC9	N,N''-(1,4-Phenylene)bis(3-fluorobenzene sulfonamide)	Investigative	44157145	C18H14F2N2O4S2	424.4	C1=CC(=CC(=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BIF01W	3,5-Dichloro-N-[4-[(3,5-dichlorophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157375	C22H20Cl4N2O4S2	582.3	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC(=CC(=C2)Cl)Cl)C)C)NS(=O)(=O)C3=CC(=CC(=C3)Cl)Cl)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BIYV27	4,4'-Bis(dimethylamino)benzil	Investigative	222570	C18H20N2O2	296.4	CN(C)C1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)N(C)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BJBN49	N,N''-(1,4-Phenylene)bis(2,3-dichlorobenzene sulfonamide)	Investigative	44157295	C18H12Cl4N2O4S2	526.2	C1=CC(=C(C(=C1)Cl)Cl)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=C(C(=CC=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BJE1I2	4-Fluoro-N-[4-[(4-fluorophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157298	C22H22F2N2O4S2	480.6	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC=C(C=C2)F)C)C)NS(=O)(=O)C3=CC=C(C=C3)F)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BJL6I9	5-Methylisatin	Investigative	11840	C9H7NO2	161.16	CC1=CC2=C(C=C1)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BJSH04	1-(5-(6-(1H-Tetrazol-5-yl)pyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	Investigative	24800681	C22H22N6O2	402.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=NC(=CC=C3)C4=NNN=N4	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BKJ9U3	N,N''-(1,4-Phenylene)bis(3,5-dichlorobenzene sulfonamide)	Investigative	44157297	C18H12Cl4N2O4S2	526.2	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=CC(=C2)Cl)Cl)NS(=O)(=O)C3=CC(=CC(=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BKR6U3	Dibromsalicil	Investigative	10662	C14H8Br2O4	400.02	C1=CC(=C(C=C1Br)C(=O)C(=O)C2=C(C=CC(=C2)Br)O)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BKY47X	N,N''-(2,3,5,6-Fluoro-1,4-phenylene)bis(4-chlorobenzene sulfonamide)	Investigative	11226329	C18H10Cl2F4N2O4S2	529.3	C1=CC(=CC=C1S(=O)(=O)NC2=C(C(=C(C(=C2F)F)NS(=O)(=O)C3=CC=C(C=C3)Cl)F)F)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BL8Y9H	4,6-Dimethyl-N1,N3-diphenylbenzene-1,3-disulfonamide	Investigative	44583034	C20H20N2O4S2	416.5	CC1=CC(=C(C=C1NS(=O)(=O)C2=CC=CC=C2)NS(=O)(=O)C3=CC=CC=C3)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BLU2M6	5-Fluoroisatin	Investigative	236566	C8H4FNO2	165.12	C1=CC2=C(C=C1F)C(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BM2K5I	5,7-Dimethylisatin	Investigative	38296	C10H9NO2	175.18	CC1=CC(=C2C(=C1)C(=O)C(=O)N2)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BM4X2Q	3,4-Dichloro-N-[4-[(3,4-dichlorophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157374	C22H20Cl4N2O4S2	582.3	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC(=C(C=C2)Cl)Cl)C)C)NS(=O)(=O)C3=CC(=C(C=C3)Cl)Cl)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BM89CE	1,2-Bis(4-fluorophenyl)-2-hydroxyethanone	Investigative	103786	C14H10F2O2	248.22	C1=CC(=CC=C1C(C(=O)C2=CC=C(C=C2)F)O)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BMDJ48	1-Phenyl-1,4-pentanedione	Investigative	136371	C11H12O2	176.21	CC(=O)CCC(=O)C1=CC=CC=C1	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BMG8I5	1-(4-Hydroxyphenyl)-2-phenylethane-1,2-dione	Investigative	142278	C14H10O3	226.23	C1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BMX8S3	3-Chloro-N-[4-[(3-chlorophenyl)sulfonylamino]-2,3,5,6-tetramethylphenyl]benzenesulfonamide	Investigative	44157370	C22H22Cl2N2O4S2	513.5	CC1=C(C(=C(C(=C1NS(=O)(=O)C2=CC(=CC=C2)Cl)C)C)NS(=O)(=O)C3=CC(=CC=C3)Cl)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BMY0Z8	6-Chloroisatin	Investigative	241331	C8H4ClNO2	181.57	C1=CC2=C(C=C1Cl)NC(=O)C2=O	Ki = 53900 nM	Poor binder
T76369	Liver carboxylesterase	BN1ZG8	N,N'-Diphenyloxamide	Investigative	69288	C14H12N2O2	240.26	C1=CC=C(C=C1)NC(=O)C(=O)NC2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BN9L7X	N-[4-(Benzenesulfonamido)-2,3,5,6-tetrachlorophenyl]benzenesulfonamide	Investigative	291540	C18H12Cl4N2O4S2	526.2	C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=C(C(=C2Cl)Cl)NS(=O)(=O)C3=CC=CC=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BNB7I1	4-Benzoylbenzoic acid	Investigative	69147	C14H10O3	226.23	C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C(=O)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BNG2S8	2,3-Pentanedione	Investigative	11747	C5H8O2	100.12	CCC(=O)C(=O)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BO6L5F	4-(N-(4-(4-Fluorophenylsulfonamido)phenyl)sulfamoyl)benzoic acid	Investigative	24445964	C19H15FN2O6S2	450.5	C1=CC(=CC=C1C(=O)O)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BO6NA7	1-Morpholin-4-ylmethyl-1H-indole-2,3-dione	Investigative	262696	C13H14N2O3	246.26	C1COCCN1CN2C3=CC=CC=C3C(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BOF8T5	4-Fluoro-N-(4-{[(4-fluorophenyl)sulfonyl]amino}phenyl)benzenesulfonamide	Investigative	1009717	C18H14F2N2O4S2	424.4	C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)F)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BOS1Z2	(4-{[(2,4-Difluorophenyl)sulfonyl]amino}phenyl)[(4-methylphenyl)sulfonyl]amine	Investigative	22772978	C19H16F2N2O4S2	438.5	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=C(C=C(C=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BOS9B3	N,N''-(1,4-Phenylene)bis(3-chlorobenzene sulfonamide)	Investigative	44157218	C18H14Cl2N2O4S2	457.4	C1=CC(=CC(=C1)Cl)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC(=CC=C3)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BOZ75J	6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinic Acid	Investigative	24951318	C21H21N3O3S	395.5	C1=CC=C(C=C1)CCCCCCC(=O)C2=NN=C(S2)C3=NC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BP04RL	1,2-Bis(4-bromo-3-nitrophenyl)ethane-1,2-dione	Investigative	5038499	C14H6Br2N2O6	458.01	C1=CC(=C(C=C1C(=O)C(=O)C2=CC(=C(C=C2)Br)[N+](=O)[O-])[N+](=O)[O-])Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BP3XO7	N,N''-(1,4-Phenylene)bis(3,5-difluoro benzene sulfonamide)	Investigative	44157293	C18H12F4N2O4S2	460.4	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=CC(=C2)F)F)NS(=O)(=O)C3=CC(=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BP5K3R	N-[4-(Benzenesulfonamido)-3-methylphenyl]benzenesulfonamide	Investigative	261836	C19H18N2O4S2	402.5	CC1=C(C=CC(=C1)NS(=O)(=O)C2=CC=CC=C2)NS(=O)(=O)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BPA9L2	1,2-Bis(4-methoxy-3-nitrophenyl)ethane-1,2-dione	Investigative	3126152	C16H12N2O8	360.27	COC1=C(C=C(C=C1)C(=O)C(=O)C2=CC(=C(C=C2)OC)[N+](=O)[O-])[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQ46RK	N,N''-(1,4-Phenylene)bis(2,4,5-trichlorobenzene sulfonamide)	Investigative	24319385	C18H10Cl6N2O4S2	595.1	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=C(C=C2Cl)Cl)Cl)NS(=O)(=O)C3=CC(=C(C=C3Cl)Cl)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQ79EC	4-Chloro-N-[4-[(4-chlorophenyl)sulfonylamino]naphthalen-1-yl]benzenesulfonamide	Investigative	1103353	C22H16Cl2N2O4S2	507.4	C1=CC=C2C(=C1)C(=CC=C2NS(=O)(=O)C3=CC=C(C=C3)Cl)NS(=O)(=O)C4=CC=C(C=C4)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQDK86	7-Fluoroisatin	Investigative	586418	C8H4FNO2	165.12	C1=CC2=C(C(=C1)F)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQF20B	Benzyl phenyl sulfone	Investigative	76561	C13H12O2S	232.3	C1=CC=C(C=C1)CS(=O)(=O)C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQJ0H8	1,1,1-Trifluoro-3-hexylsulfinylpropane-2,2-diol	Investigative	44569873	C9H17F3O3S	262.29	CCCCCCS(=O)CC(C(F)(F)F)(O)O	Ki = 79432.82 nM	Poor binder
T76369	Liver carboxylesterase	BQO63T	5-(2-(7-Phenylheptanoyl)oxazol-5-yl)furan-2-carboxylic acid	Investigative	16110717	C21H21NO5	367.4	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C3=CC=C(O3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BQP03Y	6-(2-(3-(4-Phenoxyphenyl)propanoyl)oxazol-5-yl)pyridine-2-carboxylic acid	Investigative	24799998	C24H18N2O5	414.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)CCC(=O)C3=NC=C(O3)C4=NC(=CC=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BR7XU3	1,2-Bis(2-methoxyphenyl)ethane-1,2-dione	Investigative	222475	C16H14O4	270.28	COC1=CC=CC=C1C(=O)C(=O)C2=CC=CC=C2OC	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BR9BD8	(2,3-Dioxo-2,3-dihydro-indol-1-yl)-acetic acid	Investigative	43402	C10H7NO4	205.17	C1=CC=C2C(=C1)C(=O)C(=O)N2CC(=O)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BRO7X0	(2-Naphthylsulfonyl){4-[(2-naphthylsulfonyl)amino]phenyl}amine	Investigative	1137588	C26H20N2O4S2	488.6	C1=CC=C2C=C(C=CC2=C1)S(=O)(=O)NC3=CC=C(C=C3)NS(=O)(=O)C4=CC5=CC=CC=C5C=C4	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BRZ29E	1-(5-(6-(1H-Tetrazol-5-yl)pyridin-2-yl)oxazol-2-yl)-3-(4-(phenoxymethyl)phenyl)propan-1-one	Investigative	24800683	C25H20N6O3	452.5	C1=CC=C(C=C1)OCC2=CC=C(C=C2)CCC(=O)C3=NC=C(O3)C4=NC(=CC=C4)C5=NNN=N5	IC50 = 90000 nM	Poor binder
T76369	Liver carboxylesterase	BS3PA2	1,2-Bis(2,4,6-trimethylphenyl)ethane-1,2-dione	Investigative	1972026	C20H22O2	294.4	CC1=CC(=C(C(=C1)C)C(=O)C(=O)C2=C(C=C(C=C2C)C)C)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BSBM02	4-Methoxy-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)phenyl)benzamide	Investigative	49857911	C21H16N2O4	360.4	COC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)C(=O)C(=O)C3=CC=CC=N3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BSF1E4	Furoin	Investigative	11100	C10H8O4	192.17	C1=COC(=C1)C(C(=O)C2=CC=CO2)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BT0GQ5	N-[4-[[4-(Methanesulfonamido)phenyl]disulfanyl]phenyl]methanesulfonamide	Investigative	4427802	C14H16N2O4S4	404.6	CS(=O)(=O)NC1=CC=C(C=C1)SSC2=CC=C(C=C2)NS(=O)(=O)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BT0O3Q	N-[4-(4-Chlorobenzenesulfonamido)phenyl]-4-fluorobenzene-1-sulfonamide	Investigative	16307342	C18H14ClFN2O4S2	440.9	C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)F)NS(=O)(=O)C3=CC=C(C=C3)Cl	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BT5W2F	3,4-Hexanedione	Investigative	62539	C6H10O2	114.14	CCC(=O)C(=O)CC	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BT6BD5	N,N-Diphenylbenzenesulfonamide	Investigative	597830	C18H15NO2S	309.4	C1=CC=C(C=C1)N(C2=CC=CC=C2)S(=O)(=O)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BTV86R	4-Fluoro-N-(4-{[(4-methylphenyl)sulfonyl]amino}phenyl)benzenesulfonamide	Investigative	1222869	C19H17FN2O4S2	420.5	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BU3O6V	N,N''-(1,4-Phenylene)bis(2-fluoro benzene sulfonamide)	Investigative	44157144	C18H14F2N2O4S2	424.4	C1=CC=C(C(=C1)F)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC=CC=C3F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BUBW06	N,N''-(1,4-Phenylene)bis(3,4-difluoro benzene sulfonamide)	Investigative	44157221	C18H12F4N2O4S2	460.4	C1=CC(=CC=C1NS(=O)(=O)C2=CC(=C(C=C2)F)F)NS(=O)(=O)C3=CC(=C(C=C3)F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BUE80A	N-(3-(2-Oxo-2-(pyridin-2-yl)acetyl)phenyl)-2-phenoxyacetamide	Investigative	49857910	C21H16N2O4	360.4	C1=CC=C(C=C1)OCC(=O)NC2=CC=CC(=C2)C(=O)C(=O)C3=CC=CC=N3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BV13ZL	1,2-Bis[2,5-bis(trifluoromethyl)-phenyl]ethane-1,2-dione	Investigative	44428844	C18H6F12O2	482.2	C1=CC(=C(C=C1C(F)(F)F)C(=O)C(=O)C2=C(C=CC(=C2)C(F)(F)F)C(F)(F)F)C(F)(F)F	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BV34DH	Hydrobenzoin	Investigative	95447	C14H14O2	214.26	C1=CC=C(C=C1)C(C(C2=CC=CC=C2)O)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BVB0H2	4-Ethyl isatin	Investigative	13827082	C10H9NO2	175.18	CCC1=C2C(=CC=C1)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BVGA27	N-(3-(2-Oxo-2-(pyridin-2-yl)acetyl)phenyl)-2-(thiophen-2-yl)acetamide	Investigative	49857906	C19H14N2O3S	350.4	C1=CC=NC(=C1)C(=O)C(=O)C2=CC(=CC=C2)NC(=O)CC3=CC=CS3	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BVZ2K3	2-(2,3-Dioxo-2,3-dihydro-1H-indol-1-yl)acetamide	Investigative	1906162	C10H8N2O3	204.18	C1=CC=C2C(=C1)C(=O)C(=O)N2CC(=O)N	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BW84EB	1-(2,4-Dinitrophenyl)-2-phenylethane-1,2-dione	Investigative	5004413	C14H8N2O6	300.22	C1=CC=C(C=C1)C(=O)C(=O)C2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BWKZ28	Dibenzyl sulfone	Investigative	69282	C14H14O2S	246.33	C1=CC=C(C=C1)CS(=O)(=O)CC2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BWR8O1	2,3-Butanedione	Investigative	650	C4H6O2	86.09	CC(=O)C(=O)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BXEO45	7-Methylisatin	Investigative	14313	C9H7NO2	161.16	CC1=C2C(=CC=C1)C(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BXO7I9	3-Methylcyclopentane-1,2-dione	Investigative	61209	C6H8O2	112.13	CC1CCC(=O)C1=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BYG48J	1,2-Bis[3-(trifluoromethyl)phenyl]-2-hydroxyethanone	Investigative	44428836	C16H10F6O2	348.24	C1=CC(=CC(=C1)C(F)(F)F)C(C(=O)C2=CC(=CC=C2)C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BYM6S1	6-Chloro-7-methyl-1H-indole-2,3-dione	Investigative	4513067	C9H6ClNO2	195.6	CC1=C(C=CC2=C1NC(=O)C2=O)Cl	Ki = 55300 nM	Poor binder
T76369	Liver carboxylesterase	BYS3O2	Ethanedione, bis(4-hydroxy-3-nitrophenyl)-	Investigative	24825630	C14H8N2O8	332.22	C1=CC(=C(C=C1C(=O)C(=O)C2=CC(=C(C=C2)O)[N+](=O)[O-])[N+](=O)[O-])O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BYS96N	1-Piperidin-1-ylmethyl-1H-indole-2,3-dione	Investigative	262695	C14H16N2O2	244.29	C1CCN(CC1)CN2C3=CC=CC=C3C(=O)C2=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BZ1P0A	Acetylacetone	Investigative	31261	C5H8O2	100.12	CC(=O)CC(=O)C	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BZ3D6S	N,N''-(1,4-Phenylene)bis(3-bromobenzene sulfonamide)	Investigative	44157219	C18H14Br2N2O4S2	546.3	C1=CC(=CC(=C1)Br)S(=O)(=O)NC2=CC=C(C=C2)NS(=O)(=O)C3=CC(=CC=C3)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BZ6H5I	N,N''-(2,3,5,6-Tetrafluoro-1,4-phenylene)bis(4-bromobenzene sulfonamide)	Investigative	44157440	C18H10Br2F4N2O4S2	618.2	C1=CC(=CC=C1S(=O)(=O)NC2=C(C(=C(C(=C2F)F)NS(=O)(=O)C3=CC=C(C=C3)Br)F)F)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	BZG5L2	3-Bromo-N-(7-(3-bromophenylsulfonamido)-9H-fluoren-2-yl)benzenesulfurous acid	Investigative	44157443	C25H18Br2N2O4S2	634.4	C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC(=CC=C3)Br)C4=C1C=C(C=C4)NS(=O)(=O)C5=CC(=CC=C5)Br	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0C9FO	2-(7-phenylheptanoyl)oxazole-5-carboxylic acid	Investigative	11991892	C17H19NO4	301.34	C1=CC=C(C=C1)CCCCCCC(=O)C2=NC=C(O2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0CH0K	1-(5-(pyridin-2-yl)oxazol-2-yl)octadec-9-en-1-one	Investigative	11327355	C26H38N2O2	410.6	CCCCCCCC/C=C\\CCCCCCCC(=O)C1=NC=C(O1)C2=CC=CC=N2	IC50 = 50000 nM	Poor binder
T76369	Liver carboxylesterase	D0G2DQ	5-Nitro-1H-indole-2,3-dione	Investigative	4669250	C8H4N2O4	192.13	C1=CC2=C(C=C1[N+](=O)[O-])C(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0M2EM	BENZOQUINONE	Investigative	4650	C6H4O2	108.09	C1=CC(=O)C=CC1=O	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0M8AR	1-(5-phenyloxazol-2-yl)octadec-9-en-1-one	Investigative	11154099	C27H39NO2	409.6	CCCCCCCC/C=C\\CCCCCCCC(=O)C1=NC=C(O1)C2=CC=CC=C2	IC50 = 50000 nM	Poor binder
T76369	Liver carboxylesterase	D0S6TW	6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione	Investigative	1845	C8H4Cl2N2O2	231.03	C1=C2C(=CC(=C1Cl)Cl)NC(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0SP2O	1H-Indole-2,3-dione	Investigative	7054	C8H5NO2	147.13	C1=CC=C2C(=C1)C(=O)C(=O)N2	Ki ~ 100000 nM	Poor binder
T76369	Liver carboxylesterase	D0Y0XQ	2,3-dioxoindoline-7-carboxylic acid	Investigative	2779383	C9H5NO4	191.14	C1=CC2=C(C(=C1)C(=O)O)NC(=O)C2=O	Ki ~ 100000 nM	Poor binder