TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T78127	Multidrug and toxin extrusion protein 2	D05HSC	Tubocurarine	Approved	6000	C37H41N2O6+	609.7	CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C6[C@@H](CC7=CC(=C(C=C7)O)O3)[N+](CCC6=CC(=C5O)OC)(C)C)OC	IC50 = 55500 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D06ZUK	Imipramine	Approved	3696	C19H24N2	280.4	CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31	IC50 ~ 100000 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D07HOB	Irinotecan	Approved	60838	C33H38N4O6	586.7	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7	IC50 = 78600 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D0D9FV	Orphenadrine	Approved	4601	C18H23NO	269.4	CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C	IC50 ~ 100000 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D0E6YQ	Tacrine	Approved	1935	C13H14N2	198.26	C1CCC2=NC3=CC=CC=C3C(=C2C1)N	IC50 ~ 100000 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D0F9GE	Dipyridamole	Approved	3108	C24H40N8O4	504.6	C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO	IC50 = 74000 nM	Poor binder
T78127	Multidrug and toxin extrusion protein 2	D0M4YC	Disopyramide	Approved	3114	C21H29N3O	339.5	CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C	IC50 ~ 100000 nM	Poor binder