TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T78326 N-acylethanolamine-hydrolyzing acidamidase B06HWT 4-Cyclohexylbutyl N-[(2R,3S)-2-methyl-4-oxoazetidin-3-yl]carbamate Investigative 86281147 C15H26N2O3 282.38 C[C@@H]1[C@@H](C(=O)N1)NC(=O)OCCCCC2CCCCC2 IC50 ~ 50000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B07MJS N-Pentadecylnaphthalene-2-carboxamide Investigative 134130061 C26H39NO 381.6 CCCCCCCCCCCCCCCNC(=O)C1=CC2=CC=CC=C2C=C1 IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B0T7JH (Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide Investigative 118727546 C25H35NO5 429.5 C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@@H](CCC2=CC=CC=C2)O)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B1MO9P 4-Cyclohexylbutyl N-[(2S,3S)-2-methyl-1-[(2-methylpropan-2-yl)oxy]-4-oxoazetidin-3-yl]carbamate Investigative 137635002 C19H34N2O4 354.5 C[C@H]1[C@@H](C(=O)N1OC(C)(C)C)NC(=O)OCCCCC2CCCCC2 IC50 ~ 50000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B38RYJ 4-Cyclohexylbutyl N-[(2R,3S)-1-methoxy-2-methyl-4-oxoazetidin-3-yl]carbamate Investigative 137637829 C16H28N2O4 312.4 C[C@@H]1[C@@H](C(=O)N1OC)NC(=O)OCCCCC2CCCCC2 IC50 ~ 50000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B3U6QF (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-(3-hydroxypropyl)hept-5-enamide Investigative 118727550 C26H37NO5 443.6 C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCCO)/C=C/[C@H](CCC2=CC=CC=C2)O)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B4IQB8 3-Hydroxy-N-pentadecyl-propionamide Investigative 11055663 C18H37NO2 299.5 CCCCCCCCCCCCCCCNC(=O)CCO IC50 = 54000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B5RIM4 (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-[(2S)-1-hydroxypropan-2-yl]hept-5-enamide Investigative 118727549 C26H37NO5 443.6 C[C@@H](CO)NC(=O)CCC/C=C\\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](CCC2=CC=CC=C2)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase B8E1SV (Alphas)-N-Pentadecyl-alpha-hydroxybenzeneacetamide Investigative 132547274 C23H39NO2 361.6 CCCCCCCCCCCCCCCNC(=O)[C@H](C1=CC=CC=C1)O IC50 = 78000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BB9S6H (Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-(4-iodophenyl)pent-1-enyl]-5-oxocyclopentyl]hept-5-enamide Investigative 118727547 C25H34INO5 555.4 C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@H](CCC2=CC=C(C=C2)I)O)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BJB0W6 (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]-N-[(2R)-1-hydroxypropan-2-yl]hept-5-enamide Investigative 118727548 C26H37NO5 443.6 C[C@H](CO)NC(=O)CCC/C=C\\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](CCC2=CC=CC=C2)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BLU6C7 (Z)-N-(2-Hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide Investigative 118727545 C25H35NO5 429.5 C1[C@H]([C@@H]([C@H](C1=O)C/C=C\\CCCC(=O)NCCO)/C=C/[C@H](CCC2=CC=CC=C2)O)O IC50 ~ 100000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BPQ7L6 Hexadecyl propionate Investigative 80355 C19H38O2 298.5 CCCCCCCCCCCCCCCCOC(=O)CC IC50 = 54000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BS2O5J 4-Cyclohexylbutyl N-[(3S)-1-acetyl-2-oxoazetidin-3-yl]carbamate Investigative 137653979 C16H26N2O4 310.39 CC(=O)N1C[C@@H](C1=O)NC(=O)OCCCCC2CCCCC2 IC50 ~ 50000 nM Poor binder T78326 N-acylethanolamine-hydrolyzing acidamidase BW5S8P N-Pentadecylisonicotinamide Investigative 85872110 C21H36N2O 332.5 CCCCCCCCCCCCCCCNC(=O)C1=CC=NC=C1 IC50 = 98000 nM Poor binder