TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B0A8LD	4-(4-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	17229016	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC=C(C=C2)Br	IC50 = 60100 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B0I5VC	3-Methyl-1-[[5-[3-(2-morpholin-4-ylethoxy)phenyl]-2-thiophen-2-ylthieno[2,3-d]pyrimidin-4-yl]amino]pyrrole-2,5-dione;hydrochloride	Investigative	24896725	C27H26ClN5O4S2	584.1	CC1=CC(=O)N(C1=O)NC2=C3C(=CSC3=NC(=N2)C4=CC=CS4)C5=CC(=CC=C5)OCCN6CCOCC6.Cl	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B0VRX8	Chembl4286561	Investigative	145990026	C17H17N3O	279.34	CC1=C(C(=NN1)N)C2=CC=C(C=C2)OCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B14GKR	4-[[4-[4-(2-Aminoethoxy)phenyl]pyrimidin-2-yl]amino]benzenesulfonamide	Investigative	134135188	C18H19N5O3S	385.4	C1=CC(=CC=C1C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)N)OCCN	IC50 = 65000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B1ECY3	4-(3-Chlorophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	12330558	C10H10ClN3	207.66	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B23AHI	[(4-Chloronaphthyl)sulfonyl](3-imidazolylpropyl)amine	Investigative	16004583	C16H16ClN3O2S	349.8	C1=CC=C2C(=C1)C(=CC=C2Cl)S(=O)(=O)NCCCN3C=CN=C3	IC50 = 64300 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B23JHS	Chembl4281464	Investigative	43157763	C10H9Cl2N3	242.1	CC1=C(NN=C1N)C2=CC(=C(C=C2)Cl)Cl	IC50 = 75700 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B26XDG	Chembl4280454	Investigative	62900145	C12H15N3	201.27	CC1=C(C=C(C=C1)C2=C(NN=C2N)C)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B28TJX	Chembl4292701	Investigative	145989643	C16H12Cl2N4O	347.2	CC1=C(C(=NN1C(=O)C2=CN=CC=C2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B2ET5J	Chembl4284888	Investigative	145991715	C13H13Cl2N3O	298.16	CCC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B2GND6	3-Methyl-4-(3-methylphenyl)-1H-pyrazol-5-amine	Investigative	25219675	C11H13N3	187.24	CC1=CC(=CC=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B2J7OE	Chembl4283909	Investigative	61992815	C10H9Cl2N3	242.1	CC1=C(C(=NN1)N)C2=CC(=C(C=C2)Cl)Cl	IC50 = 50900 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B2S8MW	5-(4-Chlorophenyl)thiophene-2-carboxamide	Investigative	613585	C11H8ClNOS	237.71	C1=CC(=CC=C1C2=CC=C(S2)C(=O)N)Cl	IC50 = 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B37ZTK	Chembl4166474	Investigative	145952913	C10H6F3N3O2S	289.24	C1=CC(=CC(=C1)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B3DZ2U	Chembl4282600	Investigative	145979309	C18H13N3O2S	335.4	C1=CC2=C/C(=C/C3=C(N=C(S3)NC4=CC=C(C=C4)O)O)/N=C2C=C1	IC50 = 97400 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B3O2SH	8-(Quinolin-7-ylsulfonylamino)-1-(4-sulfamoylphenyl)-4,5-dihydrobenzo[g]indazole-3-carboxamide	Investigative	10281571	C27H22N6O5S2	574.6	C1CC2=C(C3=C1C=CC(=C3)NS(=O)(=O)C4=CC5=C(C=CC=N5)C=C4)N(N=C2C(=O)N)C6=CC=C(C=C6)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B40RKW	5-Acetylenyl-3-thiophenecarboxamide, 1m	Investigative	25137999	C20H15N5O3S	405.4	C1=CC=NC(=C1)C(=O)NC2=CC=CC(=C2)C#CC3=CC(=C(S3)NC(=O)N)C(=O)N	IC50 = 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B4WN5H	3-Methyl-1-[(2-thiophen-2-ylthieno[2,3-d]pyrimidin-4-yl)amino]pyrrole-2,5-dione	Investigative	24898267	C15H10N4O2S2	342.4	CC1=CC(=O)N(C1=O)NC2=C3C=CSC3=NC(=N2)C4=CC=CS4	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B4XPM8	Chembl4284120	Investigative	145992355	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC(=CC=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B53QDN	Chembl4294749	Investigative	145993951	C12H7F6N3O2S	371.26	COC1=NSN=C1C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B56UAB	Tert-butyl N-[2-[4-[2-(4-sulfamoylanilino)pyrimidin-4-yl]phenoxy]ethyl]carbamate	Investigative	134150942	C23H27N5O5S	485.6	CC(C)(C)OC(=O)NCCOC1=CC=C(C=C1)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 138000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B58VNZ	4-[[4-(4-Cyanophenyl)pyrimidin-2-yl]amino]-N-(2-hydroxyethyl)benzenesulfonamide	Investigative	134130251	C19H17N5O3S	395.4	C1=CC(=CC=C1C#N)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)NCCO	IC50 = 111000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B5HDA2	Chembl4279494	Investigative	145980076	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NON=C2N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B61MIW	Chembl4288275	Investigative	145991182	C14H13Cl2N3O	310.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CC3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B64GVF	Chembl4280373	Investigative	145979893	C14H15Cl2N3O	312.2	CCCC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B78IVK	4-[[4-(4-Cyanophenyl)pyrimidin-2-yl]amino]benzenesulfonamide	Investigative	11688891	C17H13N5O2S	351.4	C1=CC(=CC=C1C#N)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 58000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B7A8XY	Chembl4284415	Investigative	82482456	C11H11Cl2N3	256.13	CC1=C(C(=NN1C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B7YNI6	N-(2-Aminoethyl)-4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]-N-methylbenzamide	Investigative	73351886	C22H21N5OS	403.5	CN(CCN)C(=O)C1=CC=C(C=C1)NC2=NC=CC(=N2)C3=CC4=CC=CC=C4S3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B7ZYD1	3,4-Dichloro-2-ethoxy-N-(2,2,6,6-tetramethylpiperidin-4-yl)benzenesulfonamide	Investigative	1257937	C17H26Cl2N2O3S	409.4	CCOC1=C(C=CC(=C1Cl)Cl)S(=O)(=O)NC2CC(NC(C2)(C)C)(C)C	IC50 = 55800 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B8DQ3O	Chembl4286012	Investigative	145993088	C15H17Cl2N3O2	342.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)OC(C)(C)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B8OGN1	Unii-O5YT36mst0	Investigative	9885748	C19H15F2NO	311.3	C\\1NC/C(=C\\C2=CC=CC=C2F)/C(=O)/C1=C/C3=CC=CC=C3F	IC50 = 72000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B8V5MO	3-Ureido-thieno[2,3-b]pyridine-2-carboxylic acid amide	Investigative	11658724	C9H8N4O2S	236.25	C1=CC2=C(N=C1)SC(=C2NC(=O)N)C(=O)N	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B8WX4N	Chembl4284828	Investigative	145992596	C15H15Cl2N3O	324.2	CC1=C(C(=NN1C(=O)C2CCC2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B9RCI4	2-(2,6-Dichloro-phenylamino)-7-(3-diethylamino-propenyl)-1,6-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one	Investigative	9869943	C25H27Cl2N5O	484.4	CCN(CC)C/C=C/C1=C(C2=C(C3=C(C=C2)N=C(N3C)NC4=C(C=CC=C4Cl)Cl)C(=O)N1)C	IC50 = 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	B9T0GB	3-Methyl-4-phenyl-1H-pyrazol-5-amine	Investigative	599501	C10H11N3	173.21	CC1=C(C(=NN1)N)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BA62QX	4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	24766030	C24H21N5OS	427.5	CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BAWF21	Chembl4294725	Investigative	145993662	C13H12F3N3O	283.25	CC1=NN(C(=C1C2=CC(=CC=C2)C(F)(F)F)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BBW1V3	Chembl4287493	Investigative	145990918	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BC05LD	Chembl4294669	Investigative	145994056	C17H17Cl2NO5S	418.3	CCOC1=C(C=CC(=C1Cl)Cl)S(=O)(=O)NC2=CC=C(C=C2)C(=O)OCC	IC50 = 71300 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BD16SE	2-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)benzoic acid	Investigative	44406506	C19H13N3O2S	347.4	C1=CC=C2C(=C1)C=C(S2)C3=NC(=NC=C3)NC4=CC=CC=C4C(=O)O	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BE30YH	3-(7-(4-((1S,4S)-5-Methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol	Investigative	46880136	C29H26N6O	474.6	CN1C[C@@H]2C[C@H]1CN2C3=CC=C(C=C3)C4=CC=NC5=C(C(=NN45)C6=CC=NC=C6)C7=CC(=CC=C7)O	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BE6P2G	Chembl4290916	Investigative	145987124	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BESX34	Chembl4291313	Investigative	145988918	C13H13Cl2N3O	298.16	CCC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BF50KG	Chembl4280665	Investigative	145981483	C14H17N3O	243.3	CC1=C(C=C(C=C1)C2=C(N(N=C2C)C(=O)C)N)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BFKL29	4-[[4-(4-Aminophenyl)pyrimidin-2-yl]amino]-N-(2-hydroxyethyl)benzenesulfonamide	Investigative	57446795	C18H19N5O3S	385.4	C1=CC(=CC=C1C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)NCCO)N	IC50 = 53000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BG51KO	Chembl4284710	Investigative	145991710	C11H5F6N3O2S	357.23	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BHWX34	Chembl4283382	Investigative	145990524	C12H8Cl2F3N3O	338.11	CC1=C(C(=NN1)NC(=O)C(F)(F)F)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BIO7T9	3-Amino-6-(3-aminopropoxy)-4-methylthieno[2,3-b]pyridine-2-carboxamide	Investigative	45485729	C12H16N4O2S	280.35	CC1=CC(=NC2=C1C(=C(S2)C(=O)N)N)OCCCN	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BJ4D0E	Chembl4290266	Investigative	145989760	C14H11F6N3O2	367.25	CC1=C(C(=O)NN1C)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BK2Z4I	3-Methyl-1-[(5-methyl-2-thiophen-2-ylthieno[2,3-d]pyrimidin-4-yl)amino]pyrrole-2,5-dione	Investigative	24898486	C16H12N4O2S2	356.4	CC1=CC(=O)N(C1=O)NC2=C3C(=CSC3=NC(=N2)C4=CC=CS4)C	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BK7CG0	4-(3-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	43560957	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Br	IC50 = 88000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BKJF41	Chembl4291690	Investigative	145987159	C16H17Cl2N3O	338.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCCC3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BKY2B1	Chembl4280067	Investigative	145981688	C12H8F6N4O2	354.21	CN1C(=C(N=N1)O)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BMEF20	Chembl4286341	Investigative	145992014	C17H13Cl2N3O	346.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BMY21P	[(4-Bromonaphthyl)sulfonyl](3-imidazolylpropyl)amine	Investigative	16004585	C16H16BrN3O2S	394.3	C1=CC=C2C(=C1)C(=CC=C2Br)S(=O)(=O)NCCCN3C=CN=C3	IC50 = 54700 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BN2IC3	4-Tert-Butyl-N-[2-Methyl-3-(6-{[4-(Morpholin-4-Ylcarbonyl)phenyl]amino}-7h-Purin-2-Yl)phenyl]benzamide	Investigative	53356518	C34H35N7O3	589.7	CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=NC4=C(C(=N3)NC5=CC=C(C=C5)C(=O)N6CCOCC6)NC=N4	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BNUA75	Chembl4291646	Investigative	61992242	C11H11Cl2N3	256.13	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BO6FJ9	1-(1,3-Benzodioxol-5-yl)-8-[(2,3-dichlorobenzoyl)amino]-4H-chromeno[4,3-c]pyrazole-3-carboxamide	Investigative	10165069	C25H16Cl2N4O5	523.299	C1C2=C(C3=C(O1)C=CC(=C3)NC(=O)C4=C(C(=CC=C4)Cl)Cl)N(N=C2C(=O)N)C5=CC6=C(C=C5)OCO6	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BO7XJ5	3-Methyl-4-(4-methylphenyl)-1H-pyrazol-5-amine	Investigative	24219848	C11H13N3	187.24	CC1=CC=C(C=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BPN6A8	4-(2H-1,3-Benzodioxol-5-yl)-5-methyl-1H-pyrazol-3-amine	Investigative	43157843	C11H11N3O2	217.22	CC1=C(C(=NN1)N)C2=CC3=C(C=C2)OCO3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BQ1V9G	4-[[4-[4-[2-(Dimethylamino)ethoxy]phenyl]pyrimidin-2-yl]amino]benzenesulfonamide	Investigative	134149926	C20H23N5O3S	413.5	CN(C)CCOC1=CC=C(C=C1)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 79000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BQ7SJ6	Chembl4278086	Investigative	145979124	C13H14Cl2N4O	313.18	CCNC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BS4G7P	Ethyl 2-[4-[(3-methyl-2,5-dioxopyrrol-1-yl)amino]-2-thiophen-2-ylthieno[2,3-d]pyrimidin-5-yl]acetate	Investigative	90644118	C19H16N4O4S2	428.5	CCOC(=O)CC1=CSC2=NC(=NC(=C12)NN3C(=O)C=C(C3=O)C)C4=CC=CS4	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BS9T2K	Chembl4283501	Investigative	145992122	C12H8F6N4O2	354.21	CN1NC(=O)C(=N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BT35HD	Chembl4286771	Investigative	145992036	C15H13Cl2NO5S	390.2	CCOC1=C(C=CC(=C1Cl)Cl)S(=O)(=O)NC2=CC=C(C=C2)C(=O)O	IC50 = 68000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BU63VJ	8-Nitro-1-(4-sulfamoylphenyl)-4,5-dihydrobenzo[g]indazole-3-carboxamide	Investigative	22291528	C18H15N5O5S	413.4	C1CC2=C(C3=C1C=CC(=C3)[N+](=O)[O-])N(N=C2C(=O)N)C4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BUA2G4	Chembl4282542	Investigative	1232489	C17H21NO3S	319.4	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)CO	IC50 = 98600 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BUMX85	4-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-N-isopentylbenzamide	Investigative	44406380	C24H24N4OS	416.5	CC(C)CCNC(=O)C1=CC=C(C=C1)NC2=NC=CC(=N2)C3=CC4=CC=CC=C4S3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BUNM27	Chembl4283080	Investigative	145981824	C13H9F6N3O2	353.22	CN1C=C(C(=O)N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BV56JS	Chembl4287399	Investigative	145990465	C17H19Cl2N3O	352.3	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCCCC3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BVD8E1	Chembl4283832	Investigative	145990988	C15H15Cl2N3O	324.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3CCC3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BVJ41C	Chembl4279585	Investigative	145980083	C14H14ClN3O	275.73	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C3CC3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BVT56Q	Chembl4277586	Investigative	145984375	C12H11Cl2N3O	284.14	CC1=C(C(=NN1C(=O)C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BW4N7G	Chembl4287256	Investigative	145991367	C11H5F6N3O3	341.17	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BW7J3F	Chembl4282760	Investigative	145979774	C11H10F3N3O	257.209	CC1=C(C(=NN1)N)C2=CC(=CC=C2)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BWH61I	1-[[5-[3-[2-(Dimethylamino)ethoxy]phenyl]-2-thiophen-2-ylthieno[2,3-d]pyrimidin-4-yl]amino]-3-methylpyrrole-2,5-dione;hydrochloride	Investigative	24896721	C25H24ClN5O3S2	542.1	CC1=CC(=O)N(C1=O)NC2=C3C(=CSC3=NC(=N2)C4=CC=CS4)C5=CC(=CC=C5)OCCN(C)C.Cl	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BX1O2L	3-(Carbamoylamino)-N-methyl-5-phenylthiophene-2-carboxamide	Investigative	73353353	C13H13N3O2S	275.33	CNC(=O)C1=C(C=C(S1)C2=CC=CC=C2)NC(=O)N	IC50 = 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BX2T9M	Chembl4281003	Investigative	145981500	C16H12Cl2N4O	347.2	CC1=C(C(=NN1)NC(=O)C2=CC=CC=N2)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BX4T7L	4-[4-(2-Aminophenoxy)phenyl]-N-(4-methylphenyl)pyrimidin-2-amine	Investigative	134138531	C23H20N4O	368.4	CC1=CC=C(C=C1)NC2=NC=CC(=N2)C3=CC=C(C=C3)OC4=CC=CC=C4N	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BXE71Z	3-(Benzylcarbamoylamino)-5-phenylthiophene-2-carboxamide	Investigative	73351880	C19H17N3O2S	351.4	C1=CC=C(C=C1)CNC(=O)NC2=C(SC(=C2)C3=CC=CC=C3)C(=O)N	IC50 = 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BXG7C1	Chembl4293673	Investigative	145987461	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NNNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BY41MV	3-Methyl-1-[(5-phenyl-2-thiophen-2-ylthieno[2,3-d]pyrimidin-4-yl)amino]pyrrole-2,5-dione	Investigative	24898709	C21H14N4O2S2	418.5	CC1=CC(=O)N(C1=O)NC2=C3C(=CSC3=NC(=N2)C4=CC=CS4)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BY63FM	4-[[4-(3-Cyanophenyl)pyrimidin-2-yl]amino]-N-(2-hydroxyethyl)benzenesulfonamide	Investigative	134149798	C19H17N5O3S	395.4	C1=CC(=CC(=C1)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)NCCO)C#N	IC50 = 190000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BZ4KV5	Chembl4177097	Investigative	145971744	C10H6F3N3O3	273.17	C1=CC(=CC(=C1)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	BZI24E	Chembl4283047	Investigative	145980681	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	D03MUZ	8-chloro-quinoline-3-carbonitrile	Investigative	17759555	C20H13Cl2FN6	427.3	C1=CC(=C(C=C1NC2=C3C=C(C=C(C3=NC=C2C#N)Cl)NCC4=CN=CN4)Cl)F	IC50 = 73000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	D04PEI	BMS-509744	Investigative	11467730	C32H41N5O4S2	623.8	CC1=CC(=C(C=C1SC2=CN=C(S2)NC(=O)C3=CC=C(C=C3)CNC(C)C(C)(C)C)C(=O)N4CCN(CC4)C(=O)C)OC	IC50 ~ 50000 nM	Poor binder
T78429	Inhibitor of nuclear factor kappa-B kinase beta	D0LE7J	PMID23374866C31	Investigative	58221375	C20H22N4O3	366.4	CC(C)(C#CC1=CC2=C(C=C1)NC=C2C3=NC(=NC=C3OCCOC)N)O	IC50 ~ 100000 nM	Poor binder