TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T79062	5-HT 7 receptor	B03TRB	Chembl4174981	Investigative	2962174	C22H17F3N4O	410.4	C1=CC=C(C=C1)CN2C(=NC(C2=O)(C(F)(F)F)NC3=CC=CC=N3)C4=CC=CC=C4	Ki = 84500 nM	Poor binder
T79062	5-HT 7 receptor	B0MO6A	1-(1-Benzothiophen-3-yl)-3-[4-[4-nitro-2-(trifluoromethyl)phenyl]-1,4-diazepan-1-yl]propan-1-one	Investigative	52952201	C23H22F3N3O3S	477.5	C1CN(CCN(C1)C2=C(C=C(C=C2)[N+](=O)[O-])C(F)(F)F)CCC(=O)C3=CSC4=CC=CC=C43	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	B2O1UY	2a-[4-(4-Cyclohexylpiperazin-1-yl)butyl]-1,3,4,5-tetrahydrobenzo[cd]indol-2-one	Investigative	10668422	C25H37N3O	395.6	C1CCC(CC1)N2CCN(CC2)CCCCC34CCCC5=C3C(=CC=C5)NC4=O	Ki = 100000 nM	Poor binder
T79062	5-HT 7 receptor	B3R4KH	4-[(3S)-3-[[3-(1-Benzothiophen-3-yl)-3-oxopropyl]amino]pyrrolidin-1-yl]benzonitrile	Investigative	52952305	C22H21N3OS	375.5	C1CN(C[C@H]1NCCC(=O)C2=CSC3=CC=CC=C32)C4=CC=C(C=C4)C#N	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	B4CG5X	Ikonnikoside I	Investigative	10183148	C21H18O12	462.4	C1=CC=C(C(=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O)O	IC50 = 135000 nM	Poor binder
T79062	5-HT 7 receptor	B5GQC6	1-(5-Fluoro-1-benzothiophen-3-yl)-3-[4-(4-nitrophenyl)piperazin-1-yl]propan-1-one	Investigative	52952200	C21H20FN3O3S	413.5	C1CN(CCN1CCC(=O)C2=CSC3=C2C=C(C=C3)F)C4=CC=C(C=C4)[N+](=O)[O-]	Ki = 91201.08 nM	Poor binder
T79062	5-HT 7 receptor	B6M8EY	1-(Benzo[b]thiophene-3-yl)-3-[4-(4-nitrophenyl)piperazino]-1-propanone	Investigative	52952098	C21H21N3O3S	395.5	C1CN(CCN1CCC(=O)C2=CSC3=CC=CC=C32)C4=CC=C(C=C4)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	B71NXC	3-Butylidenephthalide	Investigative	642376	C12H12O2	188.22	CCC/C=C\\1/C2=CC=CC=C2C(=O)O1	IC50 = 126600 nM	Poor binder
T79062	5-HT 7 receptor	B7V4CA	1-(1-Benzothiophen-3-yl)-3-[[(3S)-1-[4-nitro-2-(trifluoromethyl)phenyl]pyrrolidin-3-yl]amino]propan-1-one	Investigative	52952304	C22H20F3N3O3S	463.5	C1CN(C[C@H]1NCCC(=O)C2=CSC3=CC=CC=C32)C4=C(C=C(C=C4)[N+](=O)[O-])C(F)(F)F	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	B8ZBW1	Chembl4166092	Investigative	145954503	C21H20F2N2O2	370.4	C1CN(CC2=C1ON=C2C3=CC(=C(C=C3)F)F)CC[C@H](C4=CC=CC=C4)O	Ki = 71200 nM	Poor binder
T79062	5-HT 7 receptor	BBJ4R9	1-(1-Benzothiophen-3-yl)-3-[[(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]amino]propan-1-one	Investigative	52952306	C21H21N3O3S	395.5	C1CN(C[C@@H]1NCCC(=O)C2=CSC3=CC=CC=C32)C4=CC=C(C=C4)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	BCQ79Y	1-(1-Benzothiophen-3-yl)-3-[(3R)-3-(4-nitroanilino)pyrrolidin-1-yl]propan-1-one	Investigative	52952203	C21H21N3O3S	395.5	C1CN(C[C@@H]1NC2=CC=C(C=C2)[N+](=O)[O-])CCC(=O)C3=CSC4=CC=CC=C43	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	BIA50K	(8S,9Z)-8-Hydroxy-1-methoxy-9-heptadecene-4,6-diyne-3-one	Investigative	44575261	C18H26O3	290.4	CCCCCCC/C=C\\[C@@H](C#CC#CC(=O)CCOC)O	IC50 ~ 150000 nM	Poor binder
T79062	5-HT 7 receptor	BJZ8A6	1-(1-Benzothiophen-3-yl)-3-[[(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]amino]propan-1-ol	Investigative	52952423	C21H23N3O3S	397.5	C1CN(C[C@@H]1NCCC(C2=CSC3=CC=CC=C32)O)C4=CC=C(C=C4)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	BP9BA1	1-(1-Benzothiophen-3-yl)-3-[[(3S)-1-(4-nitrophenyl)pyrrolidin-3-yl]amino]propan-1-one	Investigative	52952204	C21H21N3O3S	395.5	C1CN(C[C@H]1NCCC(=O)C2=CSC3=CC=CC=C32)C4=CC=C(C=C4)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T79062	5-HT 7 receptor	BPV3G2	1-(1-Benzothiophen-3-yl)-3-(4-morpholin-4-ylpiperidin-1-yl)propan-1-one	Investigative	52952419	C20H26N2O2S	358.5	C1CN(CCC1N2CCOCC2)CCC(=O)C3=CSC4=CC=CC=C43	Ki = 53703.18 nM	Poor binder
T79062	5-HT 7 receptor	BT9FC4	(9Z,11S,16R)-Dihydroxyoctadeca-9,17-dien-12,14-diyn-1-yl acetate	Investigative	11652871	C20H28O4	332.4	CC(=O)OCCCCCCCC/C=C\\[C@@H](C#CC#C[C@@H](C=C)O)O	IC50 = 118100 nM	Poor binder
T79062	5-HT 7 receptor	BU63LY	Scutellarin	Investigative	185617	C21H18O12	462.4	C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O)O	IC50 = 63400 nM	Poor binder
T79062	5-HT 7 receptor	BUHT16	Dihydrobaicalin	Investigative	14135325	C21H20O11	448.4	C1[C@H](OC2=CC(=C(C(=C2C1=O)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)C4=CC=CC=C4	IC50 = 179000 nM	Poor binder
T79062	5-HT 7 receptor	BUIE98	1-Phenyl-2,3,4,9-tetrahydro-1H-beta-carboline	Investigative	198967	C17H16N2	248.32	C1CNC(C2=C1C3=CC=CC=C3N2)C4=CC=CC=C4	Ki = 97000 nM	Poor binder
T79062	5-HT 7 receptor	BV76AM	(3S)-3-Methyl-1-[(3S)-3-methyl-4-naphthalen-1-ylsulfonylpentyl]piperidine	Investigative	44368373	C22H31NO2S	373.6	C[C@H]1CCCN(C1)CC[C@H](C)C(C)S(=O)(=O)C2=CC=CC3=CC=CC=C32	Ki = 100000 nM	Poor binder
T79062	5-HT 7 receptor	BZ34NU	Falcarindiol	Investigative	5281148	C17H24O2	260.399	CCCCCCC/C=C\\[C@@H](C#CC#C[C@@H](C=C)O)O	IC50 = 117500 nM	Poor binder
T79062	5-HT 7 receptor	BZND03	4-[4-[3-(1-Benzothiophen-3-yl)-3-oxopropyl]piperazin-1-yl]benzonitrile	Investigative	52952100	C22H21N3OS	375.5	C1CN(CCN1CCC(=O)C2=CSC3=CC=CC=C32)C4=CC=C(C=C4)C#N	Ki ~ 100000 nM	Poor binder